JP5433505B2 - ニトロカテコール誘導体の製造方法およびその製造中間体 - Google Patents
ニトロカテコール誘導体の製造方法およびその製造中間体 Download PDFInfo
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- JP5433505B2 JP5433505B2 JP2010137973A JP2010137973A JP5433505B2 JP 5433505 B2 JP5433505 B2 JP 5433505B2 JP 2010137973 A JP2010137973 A JP 2010137973A JP 2010137973 A JP2010137973 A JP 2010137973A JP 5433505 B2 JP5433505 B2 JP 5433505B2
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- lower alkyl
- alkyl group
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- 238000000034 method Methods 0.000 title claims description 15
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- 125000000217 alkyl group Chemical group 0.000 claims description 95
- 150000001875 compounds Chemical class 0.000 claims description 94
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- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 15
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 15
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- 125000006239 protecting group Chemical group 0.000 claims description 5
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- 125000000592 heterocycloalkyl group Chemical group 0.000 description 8
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- 125000001072 heteroaryl group Chemical group 0.000 description 7
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- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 description 6
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- YPJUNDFVDDCYIH-UHFFFAOYSA-N perfluorobutyric acid Chemical compound OC(=O)C(F)(F)C(F)(F)C(F)(F)F YPJUNDFVDDCYIH-UHFFFAOYSA-N 0.000 description 1
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Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| JP2010137973A JP5433505B2 (ja) | 2009-06-18 | 2010-06-17 | ニトロカテコール誘導体の製造方法およびその製造中間体 |
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| JP2009145084 | 2009-06-18 | ||
| JP2009145084 | 2009-06-18 | ||
| JP2010137973A JP5433505B2 (ja) | 2009-06-18 | 2010-06-17 | ニトロカテコール誘導体の製造方法およびその製造中間体 |
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| JP2011021009A JP2011021009A (ja) | 2011-02-03 |
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| JP2020158391A (ja) * | 2017-06-13 | 2020-10-01 | 株式会社富士薬品 | 新規ニトロカテコール誘導体 |
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| AR058439A1 (es) * | 2005-07-26 | 2008-02-06 | Portela & Ca Sa | Derivados de nitrocatecol como inhibidores de comt. procesos de obtencion y composiciones farmaceuticas. |
| JP2008308495A (ja) * | 2007-05-17 | 2008-12-25 | Kissei Pharmaceut Co Ltd | 新規なカテコール誘導体、それを含有する医薬組成物およびそれらの用途 |
| CA2708447C (en) * | 2007-12-25 | 2016-05-10 | Kissei Pharmaceutical Co., Ltd. | Novel catechol derivative, pharmaceutical composition containing the same, use of the catechol derivative, and use of the pharmaceutical composition |
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