JP5420126B2 - ｐＨ非依存延長放出性医薬組成物 - Google Patents

ｐＨ非依存延長放出性医薬組成物 Download PDF

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Publication number
JP5420126B2
JP5420126B2 JP2000596913A JP2000596913A JP5420126B2 JP 5420126 B2 JP5420126 B2 JP 5420126B2 JP 2000596913 A JP2000596913 A JP 2000596913A JP 2000596913 A JP2000596913 A JP 2000596913A JP 5420126 B2 JP5420126 B2 JP 5420126B2
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Japan
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polymer
weight
acid
composition
water
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Expired - Lifetime
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JP2000596913A
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English (en)
Japanese (ja)
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JP2002536318A5 (https=
JP2002536318A (ja
Inventor
アン，ケビン・アール
チウ，イーホン
ラオ，ベンカトラマーナ
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Abbott Laboratories
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Abbott Laboratories
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000596913A 1999-02-04 2000-01-26 ｐＨ非依存延長放出性医薬組成物 Expired - Lifetime JP5420126B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24467899A 1999-02-04 1999-02-04
US09/244,678 1999-02-04
PCT/US2000/001954 WO2000045793A1 (en) 1999-02-04 2000-01-26 Ph independent extended release pharmaceutical formulation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011116089A Division JP5420590B2 (ja) 1999-02-04 2011-05-24 ｐＨ非依存延長放出性医薬組成物

Publications (3)

Publication Number Publication Date
JP2002536318A JP2002536318A (ja) 2002-10-29
JP2002536318A5 JP2002536318A5 (https=) 2013-11-14
JP5420126B2 true JP5420126B2 (ja) 2014-02-19

Family

ID=22923698

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000596913A Expired - Lifetime JP5420126B2 (ja) 1999-02-04 2000-01-26 ｐＨ非依存延長放出性医薬組成物
JP2011116089A Expired - Lifetime JP5420590B2 (ja) 1999-02-04 2011-05-24 ｐＨ非依存延長放出性医薬組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011116089A Expired - Lifetime JP5420590B2 (ja) 1999-02-04 2011-05-24 ｐＨ非依存延長放出性医薬組成物

Country Status (10)

Country Link
EP (1) EP1146864B1 (https=)
JP (2) JP5420126B2 (https=)
AT (1) ATE424191T1 (https=)
CA (1) CA2361496C (https=)
CY (1) CY1108863T1 (https=)
DE (1) DE60041691D1 (https=)
DK (1) DK1146864T3 (https=)
ES (1) ES2321908T3 (https=)
PT (1) PT1146864E (https=)
WO (1) WO2000045793A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6511678B2 (en) 1998-12-18 2003-01-28 Abbott Laboratories Controlled release formulation of divalproex sodium
US6713086B2 (en) 1998-12-18 2004-03-30 Abbott Laboratories Controlled release formulation of divalproex sodium
US6528090B2 (en) 1998-12-18 2003-03-04 Abbott Laboratories Controlled release formulation of divalproex sodium
US6419953B1 (en) 1998-12-18 2002-07-16 Abbott Laboratories Controlled release formulation of divalproex sodium
US20020025341A1 (en) * 1998-12-18 2002-02-28 Yihong Qiu Controlled release formulation of divalproex sodium
WO2002051402A1 (en) * 2000-12-22 2002-07-04 Abbott Laboratories Controlled release formulation of divalproex sodium
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US20040175423A1 (en) * 2003-02-05 2004-09-09 Daniella Licht Sustained release formulation of N- (2-propylpentanoyl) glycinamide and related compounds
WO2007036952A2 (en) 2005-07-01 2007-04-05 Rubicon Research Pvt Ltd. Novel sustained release dosage form
BRPI1013901A2 (pt) * 2009-04-29 2019-09-24 Rexahn Pharmaceuticals Inc formulação de clavulanato para neuroproteção e tratamento de distúrbios neurodegenerativos
CN107811985B (zh) * 2016-09-13 2021-05-28 四川科瑞德制药股份有限公司 一种抗癫痫缓释制剂及其制备方法与用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL72381A (en) * 1983-07-20 1988-03-31 Sanofi Sa Pharmaceutical composition based on valproic acid
US4792452A (en) * 1987-07-28 1988-12-20 E. R. Squibb & Sons, Inc. Controlled release formulation
DE3809764A1 (de) * 1988-03-23 1989-10-05 Knoll Ag Mischung aus alginaten und polyacrylaten und deren verwendung
FR2643556B1 (fr) * 1989-02-27 1993-03-05 Sanofi Sa Composition pharmaceutique a liberation prolongee d'acide valproique
US5102668A (en) * 1990-10-05 1992-04-07 Kingaform Technology, Inc. Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH
AU6824996A (en) * 1995-08-17 1997-03-12 Dyer, Alison Margaret Controlled release products
AUPN969796A0 (en) * 1996-05-07 1996-05-30 F.H. Faulding & Co. Limited Taste masked liquid suspensions
WO1998040060A1 (en) * 1997-03-11 1998-09-17 Hexal Ag Solid, non-deliquescent formulations of sodium valproate

Also Published As

Publication number Publication date
DK1146864T3 (da) 2009-05-11
ES2321908T3 (es) 2009-06-15
ATE424191T1 (de) 2009-03-15
CY1108863T1 (el) 2014-07-02
EP1146864A1 (en) 2001-10-24
EP1146864B1 (en) 2009-03-04
DE60041691D1 (de) 2009-04-16
PT1146864E (pt) 2009-03-20
JP5420590B2 (ja) 2014-02-19
JP2002536318A (ja) 2002-10-29
JP2011241218A (ja) 2011-12-01
WO2000045793A1 (en) 2000-08-10
CA2361496A1 (en) 2000-08-10
CA2361496C (en) 2011-06-07

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