JP5416125B2 - 免疫アジュバントとして有用な糖脂質の類似体 - Google Patents

免疫アジュバントとして有用な糖脂質の類似体 Download PDF

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Publication number
JP5416125B2
JP5416125B2 JP2010528504A JP2010528504A JP5416125B2 JP 5416125 B2 JP5416125 B2 JP 5416125B2 JP 2010528504 A JP2010528504 A JP 2010528504A JP 2010528504 A JP2010528504 A JP 2010528504A JP 5416125 B2 JP5416125 B2 JP 5416125B2
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alkyl
composition
groups
compound
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JP2010528504A
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Japanese (ja)
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JP2011510910A (ja
JP2011510910A5 (enExample
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ルイジ パンツァ，
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2010528504A 2007-10-12 2008-10-10 免疫アジュバントとして有用な糖脂質の類似体 Expired - Fee Related JP5416125B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97978507P 2007-10-12 2007-10-12
US60/979,785 2007-10-12
PCT/IB2008/003263 WO2009060305A2 (en) 2007-10-12 2008-10-10 Analogues of glycolipids useful as immunoadjuvants

Publications (3)

Publication Number Publication Date
JP2011510910A JP2011510910A (ja) 2011-04-07
JP2011510910A5 JP2011510910A5 (enExample) 2012-11-22
JP5416125B2 true JP5416125B2 (ja) 2014-02-12

Family

ID=40626266

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010528504A Expired - Fee Related JP5416125B2 (ja) 2007-10-12 2008-10-10 免疫アジュバントとして有用な糖脂質の類似体

Country Status (8)

Country Link
US (1) US8697659B2 (enExample)
EP (1) EP2483287B1 (enExample)
JP (1) JP5416125B2 (enExample)
CN (1) CN102066394B (enExample)
AU (1) AU2008326138B2 (enExample)
CA (1) CA2702344C (enExample)
ES (1) ES2574825T3 (enExample)
WO (1) WO2009060305A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5640079B2 (ja) 2009-05-18 2014-12-10 シグモイド・ファーマ・リミテッドＳｉｇｍｏｉｄ Ｐｈａｒｍａ Ｌｉｍｉｔｅｄ 油滴含有組成物
CN102573802A (zh) * 2009-08-12 2012-07-11 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
AU2013237497B2 (en) * 2012-03-19 2016-05-12 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Carbohydrate-glycolipid conjugate vaccines
GB201212010D0 (en) 2012-07-05 2012-08-22 Sigmoid Pharma Ltd Formulations
PT3215127T (pt) 2014-11-07 2021-02-10 Sublimity Therapeutics Ltd Composições que compreendem ciclosporina
WO2022256467A1 (en) * 2021-06-02 2022-12-08 The Charlotte Mecklenburg Hospital Authority D/B/A Atrium Health Compositions and methods comprising deoxy-pentitols

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW261533B (enExample) * 1992-07-16 1995-11-01 Kirin Brewery
EP1437358B1 (en) 2001-08-16 2006-10-18 Daiichi Asubio Pharma Co., Ltd. Novel glycolipid and remedial agent for autoimmune disease containing the same as active ingredient
GB0314682D0 (en) * 2003-06-24 2003-07-30 Isis Innovation Materials and methods relating to the modulation of T cell response to soluble antigen
EP1784196B1 (en) 2004-08-27 2016-12-21 Albert Einstein College Of Medicine Of Yeshiva University Ceramide derivatives as modulators of immunity and autoimmunity
US7923013B2 (en) * 2004-12-28 2011-04-12 The Rockefeller University Glycolipids and analogues thereof as antigens for NKT cells
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions

Also Published As

Publication number Publication date
CN102066394A (zh) 2011-05-18
US8697659B2 (en) 2014-04-15
EP2483287B1 (en) 2016-03-16
WO2009060305A2 (en) 2009-05-14
CN102066394B (zh) 2015-04-01
US20110033485A1 (en) 2011-02-10
CA2702344C (en) 2016-09-27
CA2702344A1 (en) 2009-05-14
AU2008326138B2 (en) 2013-10-17
ES2574825T3 (es) 2016-06-22
WO2009060305A3 (en) 2013-05-23
EP2483287A2 (en) 2012-08-08
AU2008326138A1 (en) 2009-05-14
JP2011510910A (ja) 2011-04-07

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