JP5394246B2 - 抗体及びイムノコンジュゲートとこれらの使用方法 - Google Patents
抗体及びイムノコンジュゲートとこれらの使用方法 Download PDFInfo
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- JP5394246B2 JP5394246B2 JP2009534901A JP2009534901A JP5394246B2 JP 5394246 B2 JP5394246 B2 JP 5394246B2 JP 2009534901 A JP2009534901 A JP 2009534901A JP 2009534901 A JP2009534901 A JP 2009534901A JP 5394246 B2 JP5394246 B2 JP 5394246B2
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| TWI882308B (zh) * | 2010-09-29 | 2025-05-01 | 美商艾澤西公司 | 與191p4d12蛋白結合之抗體藥物共軛物(adc) |
| KR20130133205A (ko) * | 2010-11-10 | 2013-12-06 | 제넨테크, 인크. | 신경계 질환 면역요법을 위한 방법 및 조성물 |
| KR101529810B1 (ko) * | 2011-04-01 | 2015-06-26 | 와이어쓰 엘엘씨 | 항체-약물 접합체 |
| EP2780039B9 (en) | 2011-11-17 | 2018-04-18 | Pfizer Inc | Cytotoxic peptides and antibody drug conjugates thereof |
| CN104067127A (zh) * | 2011-11-29 | 2014-09-24 | 霍夫曼-拉罗奇有限公司 | 用于前列腺癌分析的组合物和方法 |
| EP4458859A3 (en) * | 2012-04-04 | 2025-01-22 | Perseus Proteomics Inc. | Conjugate of anti-cdh3 (p-cadherin) antibody and drug |
| CN103566377A (zh) * | 2012-07-18 | 2014-02-12 | 上海博笛生物科技有限公司 | 癌症的靶向免疫治疗 |
| KR102306490B1 (ko) * | 2013-03-15 | 2021-09-28 | 리제너론 파아마슈티컬스, 인크. | 생물학적 활성 분자, 그의 접합체 및 치료 용도 |
| SG11201605296SA (en) * | 2014-01-10 | 2016-07-28 | Birdie Biopharmaceuticals Inc | Compounds and compositions for treating her2 positive tumors |
| EP3096797A1 (en) * | 2014-01-24 | 2016-11-30 | F. Hoffmann-La Roche AG | Methods of using anti-steap1 antibodies and immunoconjugates |
| CN110841074B (zh) * | 2014-03-21 | 2023-07-18 | 艾伯维公司 | 抗-egfr抗体及抗体药物偶联物 |
| CN106536540A (zh) | 2014-07-24 | 2017-03-22 | 基因泰克公司 | 将试剂缀合至含有至少一个三硫键的蛋白质中的巯基部分的方法 |
| EP3356409A2 (en) * | 2015-10-02 | 2018-08-08 | H. Hoffnabb-La Roche Ag | Bispecific t cell activating antigen binding molecules |
| CA3104386A1 (en) * | 2018-07-02 | 2020-01-09 | Amgen Inc. | Anti-steap1 antigen-binding protein |
| AU2019392090A1 (en) | 2018-12-03 | 2021-06-17 | Agensys, Inc. | Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof |
| JP2023511184A (ja) * | 2020-01-22 | 2023-03-16 | メドイミューン・リミテッド | 化合物及びその複合体 |
| CN111494645B (zh) * | 2020-05-20 | 2022-09-30 | 中国药科大学 | 抗人dll4人源化抗体与美登素生物碱dm1的偶联物及其制备方法与应用 |
| EP4346908A1 (en) * | 2021-05-24 | 2024-04-10 | RemeGen Co., Ltd. | Use of her2-targeting antibody-drug conjugate in treatment of her2-low expressing breast cancer |
| US20230270874A1 (en) * | 2021-07-19 | 2023-08-31 | Mabplex International Co., Ltd. | Antibody drug conjugate loaded with binary toxins and its application |
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| IL150018A0 (en) * | 1999-12-06 | 2002-12-01 | Agensys Inc | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof |
| US8008442B2 (en) * | 2004-04-22 | 2011-08-30 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
| CN101065151B (zh) * | 2004-09-23 | 2014-12-10 | 健泰科生物技术公司 | 半胱氨酸改造的抗体和偶联物 |
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| JP5837019B2 (ja) | 2015-12-24 |
| JP2014042522A (ja) | 2014-03-13 |
| JP2010523469A (ja) | 2010-07-15 |
| JP6185540B2 (ja) | 2017-08-23 |
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