JP5339257B2 - 可変ピッチアレイスポッタ - Google Patents
可変ピッチアレイスポッタ Download PDFInfo
- Publication number
- JP5339257B2 JP5339257B2 JP2010267350A JP2010267350A JP5339257B2 JP 5339257 B2 JP5339257 B2 JP 5339257B2 JP 2010267350 A JP2010267350 A JP 2010267350A JP 2010267350 A JP2010267350 A JP 2010267350A JP 5339257 B2 JP5339257 B2 JP 5339257B2
- Authority
- JP
- Japan
- Prior art keywords
- dispensing
- pitch
- heads
- arrangement
- dispensing heads
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1067—Multiple transfer devices for transfer to or from containers having different spacing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0262—Drop counters; Drop formers using touch-off at substrate or container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
- B01J2219/00367—Pipettes capillary
- B01J2219/00369—Pipettes capillary in multiple or parallel arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00387—Applications using probes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/021—Adjust spacings in an array of wells, pipettes or holders, format transfer between arrays of different size or geometry
- B01L2200/022—Variable spacings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0838—Capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
- B01L2400/022—Drop detachment mechanisms of single droplets from nozzles or pins droplet contacts the surface of the receptacle
- B01L2400/025—Drop detachment mechanisms of single droplets from nozzles or pins droplet contacts the surface of the receptacle tapping tip on substrate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Description
2各格了点
3、15、25、46キャピラリー
4、5輪
6シャフト
7交点
8固定ロッド
9可動ロッド
10、27支柱
11、12、61軸
13ガイドロッド
14ホルダ
16貫通孔
17垂直孔
21、23孔
22、40上板
24、41下板
28モータ
29、45ギア
30、44ラックギア
32マイクロアレイ
33上ストッパ
34下ストッパ
35ばね
42開口溝
43、62モータ
47ガイドパイプ
48フランジ
50フレーム
51、52ガイド
60ガイドロッドホルダ
Claims (2)
- 先端部に注出部を有する複数の分注ヘッドを有する分注装置であって、該複数の分注ヘッドが縦m個、横n個のm×nのアレイ(m、n≧1、但し、m=1かつn=1の場合を除く)を形成し、該複数の分注ヘッドの縦方向および横方向の少なくとも一方の配列ピッチを変えることのできる機構を備え、
前記機構は、分注位置に対応する配列で孔を有する板と該配列に対して相似な配列で孔を有する板とを間隔をもって上下に配置し、該複数の分注ヘッドを該二枚の板の相似対称な位置関係にある孔を貫通することによって摺動自在に保持し、
該二枚の板の一方は、上下方向に延在する複数の支柱が挿入され、当該支柱に沿って上下方向に移動可能に案内され、該二枚の板の間隔を狭めたり拡げたりすることにより、前記複数の分注ヘッドの相対的な傾斜角度を変えて、前記注出口のピッチを変更する、ことを特徴とする分注装置。 - 前記分注ヘッドを注出口を含め全体を微細管で構成した、ことを特徴とする請求項1に記載の分注装置。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2010267350A JP5339257B2 (ja) | 2006-07-12 | 2010-11-30 | 可変ピッチアレイスポッタ |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006192000 | 2006-07-12 | ||
JP2006192000 | 2006-07-12 | ||
JP2007061165 | 2007-03-12 | ||
JP2007061165 | 2007-03-12 | ||
JP2010267350A JP5339257B2 (ja) | 2006-07-12 | 2010-11-30 | 可変ピッチアレイスポッタ |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008524754A Division JP4686769B2 (ja) | 2006-07-12 | 2007-06-27 | 可変ピッチアレイスポッタ |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2011043519A JP2011043519A (ja) | 2011-03-03 |
JP5339257B2 true JP5339257B2 (ja) | 2013-11-13 |
Family
ID=38923118
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008524754A Active JP4686769B2 (ja) | 2006-07-12 | 2007-06-27 | 可変ピッチアレイスポッタ |
JP2010267350A Active JP5339257B2 (ja) | 2006-07-12 | 2010-11-30 | 可変ピッチアレイスポッタ |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008524754A Active JP4686769B2 (ja) | 2006-07-12 | 2007-06-27 | 可変ピッチアレイスポッタ |
Country Status (3)
Country | Link |
---|---|
US (1) | US20090305910A1 (ja) |
JP (2) | JP4686769B2 (ja) |
WO (1) | WO2008007556A1 (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8808625B2 (en) | 2008-01-11 | 2014-08-19 | National Institute Of Advanced Industrial Science And Technology | Dispensing apparatus and a dispensing method |
WO2011157303A1 (en) * | 2010-06-18 | 2011-12-22 | Tecan Trading Ag | Spread sheare |
CN102539806B (zh) * | 2012-02-16 | 2013-05-08 | 哈尔滨工业大学(威海) | 一种多通道液体加样等量分距装置 |
KR101909470B1 (ko) * | 2016-12-23 | 2018-10-22 | (주)카스 인 바이오 | 웰 플레이트용 저출력 레이저 또는 led 조사 장치 |
JP2022011167A (ja) * | 2020-06-29 | 2022-01-17 | 澁谷工業株式会社 | 液体吸引排出装置 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS554523A (en) * | 1978-06-24 | 1980-01-14 | Nippon Tectron Co Ltd | Sample dispenser in automatic chemical analytical apparatus |
FR2583655B3 (fr) * | 1985-06-24 | 1987-09-11 | Bionova Sarl | Dispositif d'adaptation a diverses geometries de stations de pipetage a voies multiples |
US5061449A (en) * | 1989-07-25 | 1991-10-29 | Matrix Technologies, Corp. | Expandable multi-channel pipetter |
US5312757A (en) * | 1991-05-02 | 1994-05-17 | Olympus Optical Co., Ltd. | Sample distributing method |
JPH09318636A (ja) * | 1996-05-30 | 1997-12-12 | Suzuki Motor Corp | 分注装置 |
JPH1048100A (ja) * | 1996-08-06 | 1998-02-20 | Sony Corp | 分注装置 |
JP3423187B2 (ja) * | 1997-04-16 | 2003-07-07 | 三洋電機株式会社 | 分注装置 |
US6146594A (en) * | 1999-02-10 | 2000-11-14 | Robbins Scientific Corporation | Syringe array with adjustable needle spacing |
JP3723021B2 (ja) * | 1999-09-30 | 2005-12-07 | 富士写真フイルム株式会社 | マイクロアレイチップ製造装置 |
US6451263B1 (en) * | 1999-11-04 | 2002-09-17 | Helena Laboratories Corporation | Pipette adapter |
JP2001211873A (ja) * | 2000-02-03 | 2001-08-07 | Mitsubishi Chemicals Corp | スポッティングヘッド |
US20030223910A1 (en) * | 2002-02-12 | 2003-12-04 | Molecular Devices Corp. | Pipettor systems and components |
JP2003315352A (ja) * | 2002-04-17 | 2003-11-06 | Takabayashi Seisakusho:Kk | 液体分注装置 |
JP2005091339A (ja) * | 2003-09-18 | 2005-04-07 | Toru Hiramatsu | 液体分注装置 |
-
2007
- 2007-06-27 JP JP2008524754A patent/JP4686769B2/ja active Active
- 2007-06-27 WO PCT/JP2007/062926 patent/WO2008007556A1/ja active Application Filing
- 2007-06-27 US US12/309,072 patent/US20090305910A1/en not_active Abandoned
-
2010
- 2010-11-30 JP JP2010267350A patent/JP5339257B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
WO2008007556A1 (fr) | 2008-01-17 |
JPWO2008007556A1 (ja) | 2009-12-10 |
JP4686769B2 (ja) | 2011-05-25 |
JP2011043519A (ja) | 2011-03-03 |
US20090305910A1 (en) | 2009-12-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5339257B2 (ja) | 可変ピッチアレイスポッタ | |
US7575937B2 (en) | Device and method for disposing pipette syringes in a system used for manipulating liquid samples | |
US9120071B2 (en) | Variable pitch array spotter | |
EP1884781B1 (en) | High-speed automatic dispensing device with replaceable dispensing head and dispensing station | |
US8808625B2 (en) | Dispensing apparatus and a dispensing method | |
US6296702B1 (en) | Apparatus and method for spotting a substrate | |
EP1738179B1 (de) | Vorrichtung für das transportieren oder untersuchen von flüssigkeiten | |
EP2572786B1 (de) | Pipetiervorrichtung mit einem Pipetierkopf mit einer Vielzahl von in einem Anordnungsmuster angeordneten Pipetierkanälen | |
US6841130B2 (en) | Pipetting method and multichannel pipetting apparatus | |
US6759012B2 (en) | Pin holder for a microarraying apparatus | |
US20070092410A1 (en) | Device for pipetting solution from one plate format to a different plate platform using movable position pipette tips | |
JP2008507700A (ja) | 流体の分散によって希釈物を形成するための方法および装置 | |
JPS621459A (ja) | 多数ピペツト操作場所を異つた状態に適合する装置 | |
JP2001211873A (ja) | スポッティングヘッド | |
US20020176805A1 (en) | Spotting device for fabricating microarrays of biological samples and spotting pin inserted therein | |
CN112206843A (zh) | 一种转移液体的装置 | |
CN104962454A (zh) | 全自动核酸分子杂交仪 | |
CN107199062B (zh) | 一种超微量液体加样器 | |
CN114545012A (zh) | 适用于1至20毫升移液操作的多通道批量移液设备 | |
JP2008168251A (ja) | 連続液膜更新機能を有する気液接触機構 | |
CN115616235A (zh) | 一种1536孔板的自动化微量点样设备 | |
JP2007303985A (ja) | 創薬用チューブ手動式ピッキング装置 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20101209 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20120925 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20121126 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130430 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130628 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20130723 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20130729 |
|
R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 Ref document number: 5339257 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
S533 | Written request for registration of change of name |
Free format text: JAPANESE INTERMEDIATE CODE: R313533 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |