JP5335239B2 - ミオスタチンアイソフォーム - Google Patents

ミオスタチンアイソフォーム Download PDF

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Publication number
JP5335239B2
JP5335239B2 JP2007534532A JP2007534532A JP5335239B2 JP 5335239 B2 JP5335239 B2 JP 5335239B2 JP 2007534532 A JP2007534532 A JP 2007534532A JP 2007534532 A JP2007534532 A JP 2007534532A JP 5335239 B2 JP5335239 B2 JP 5335239B2
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JP
Japan
Prior art keywords
polynucleotide
seq
polypeptide
nos
sequence
Prior art date
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Expired - Fee Related
Application number
JP2007534532A
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English (en)
Japanese (ja)
Other versions
JP2008514227A (ja
JP2008514227A5 (enExample
Inventor
フェレンツ・ジーンプロング
クリストファー・デイビッド・マクマホン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Myopharm Ltd
Original Assignee
Myostin Therapeutics Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NZ53569604A external-priority patent/NZ535696A/en
Application filed by Myostin Therapeutics Pty Ltd filed Critical Myostin Therapeutics Pty Ltd
Publication of JP2008514227A publication Critical patent/JP2008514227A/ja
Publication of JP2008514227A5 publication Critical patent/JP2008514227A5/ja
Application granted granted Critical
Publication of JP5335239B2 publication Critical patent/JP5335239B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2007534532A 2004-09-30 2005-09-30 ミオスタチンアイソフォーム Expired - Fee Related JP5335239B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
NZ53569604A NZ535696A (en) 2004-09-30 2004-09-30 Myostatin splice variants ( MSV )
NZ535696 2004-09-30
NZ53839605 2005-02-22
NZ538396 2005-02-22
PCT/NZ2005/000250 WO2006036074A1 (en) 2004-09-30 2005-09-30 Myostatin isoform

Publications (3)

Publication Number Publication Date
JP2008514227A JP2008514227A (ja) 2008-05-08
JP2008514227A5 JP2008514227A5 (enExample) 2008-10-23
JP5335239B2 true JP5335239B2 (ja) 2013-11-06

Family

ID=36119161

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007534532A Expired - Fee Related JP5335239B2 (ja) 2004-09-30 2005-09-30 ミオスタチンアイソフォーム

Country Status (6)

Country Link
US (2) US20080118487A1 (enExample)
EP (1) EP1799709B1 (enExample)
JP (1) JP5335239B2 (enExample)
AT (1) ATE552272T1 (enExample)
CA (1) CA2582940A1 (enExample)
WO (1) WO2006036074A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100898149B1 (ko) 2007-04-05 2009-05-19 주식회사 에스엔피 제네틱스 소의 근내지방도와 연관되어 있는 티틴-캡 다형성
SG10201800800YA (en) 2013-05-06 2018-03-28 Scholar Rock Inc Compositions and methods for growth factor modulation
WO2019195679A1 (en) * 2018-04-06 2019-10-10 Intrexon Corporation Tilapia with enhanced growth characteristics
US12202869B2 (en) 2019-03-01 2025-01-21 Knc Laboratories Co., Ltd. Inhibition of myostatin signal by myostatin splice variant-derived protein and utilization thereof
CN115201474A (zh) * 2022-08-12 2022-10-18 万华普曼生物工程有限公司 一种新型冠状病毒抗体的快速检测试剂盒及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4487325A (en) 1982-07-06 1984-12-11 Owens-Illinois, Inc. Crown closures and containers
US7393682B1 (en) 1993-03-19 2008-07-01 The Johns Hopkins University School Of Medicine Polynucleotides encoding promyostatin polypeptides
US5874409A (en) * 1995-06-07 1999-02-23 La Jolla Pharmaceutical Company APL immunoreactive peptides, conjugates thereof and methods of treatment for APL antibody-mediated pathologies
WO1998033887A1 (en) 1997-02-05 1998-08-06 The Johns Hopkins University School Of Medicine Growth differentiation factor-8
US6656475B1 (en) * 1997-08-01 2003-12-02 The Johns Hopkins University School Of Medicine Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
US6369201B1 (en) * 1998-02-19 2002-04-09 Metamorphix International, Inc. Myostatin multimers
CN1384757A (zh) 1999-07-20 2002-12-11 法麦克萨有限公司 下调gdf-8活性的方法
AU782925B2 (en) 2000-01-18 2005-09-08 Orico Limited Myostatin and mimetics thereof
JP2005533855A (ja) 2002-07-24 2005-11-10 インターツェル・アクチェンゲゼルシャフト 病原性ウイルスからの別のリーディングフレームによりコードされる抗原
ATE461275T1 (de) * 2002-09-16 2010-04-15 Univ Johns Hopkins Metalloproteaseaktivierung von myostatin und verfahren zur modulation der myostatinaktivität
NZ529860A (en) * 2003-11-28 2006-10-27 Ovita Ltd Muscle growth regulator mighty and use in promoting muscle mass and treating muscle wasting diseases
WO2005066204A2 (en) * 2003-12-31 2005-07-21 Schering-Plough Ltd. Neutralizing epitope-based growth enhancing vaccine
NZ538097A (en) 2005-02-07 2006-07-28 Ovita Ltd Method and compositions for improving wound healing
US20070190056A1 (en) 2006-02-07 2007-08-16 Ravi Kambadur Muscle regeneration compositions and uses therefor
EP2054434B1 (en) * 2006-08-03 2017-03-15 Myostin Therapeutics Pty Ltd Myostatin antagonists

Also Published As

Publication number Publication date
EP1799709A1 (en) 2007-06-27
US20080118487A1 (en) 2008-05-22
US8455448B2 (en) 2013-06-04
WO2006036074A1 (en) 2006-04-06
EP1799709B1 (en) 2012-04-04
CA2582940A1 (en) 2006-04-06
ATE552272T1 (de) 2012-04-15
JP2008514227A (ja) 2008-05-08
US20110258712A1 (en) 2011-10-20
EP1799709A4 (en) 2008-11-12

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