JP5329095B2 - 次亜ハロゲン酸と組み合わせる、ｎ−ハロゲン化アミノ酸およびｎ，ｎ−ジハロゲン化アミノ酸 - Google Patents

次亜ハロゲン酸と組み合わせる、ｎ−ハロゲン化アミノ酸およびｎ，ｎ−ジハロゲン化アミノ酸 Download PDF

Info

Publication number
JP5329095B2
JP5329095B2 JP2007553252A JP2007553252A JP5329095B2 JP 5329095 B2 JP5329095 B2 JP 5329095B2 JP 2007553252 A JP2007553252 A JP 2007553252A JP 2007553252 A JP2007553252 A JP 2007553252A JP 5329095 B2 JP5329095 B2 JP 5329095B2
Authority
JP
Japan
Prior art keywords
acid
group
pharmaceutical composition
derivative
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2007553252A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008531479A (ja
JP2008531479A5 (enExample
Inventor
ラミン・ナジャフィ
マンスール・バシリ
ワン・ル
ベーザド・コースロビ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novabay Pharmaceuticals Inc
Original Assignee
Novabay Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novabay Pharmaceuticals Inc filed Critical Novabay Pharmaceuticals Inc
Publication of JP2008531479A publication Critical patent/JP2008531479A/ja
Publication of JP2008531479A5 publication Critical patent/JP2008531479A5/ja
Application granted granted Critical
Publication of JP5329095B2 publication Critical patent/JP5329095B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/16—Fluorine compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2007553252A 2005-01-25 2006-01-25 次亜ハロゲン酸と組み合わせる、ｎ−ハロゲン化アミノ酸およびｎ，ｎ−ジハロゲン化アミノ酸 Expired - Fee Related JP5329095B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64736605P 2005-01-25 2005-01-25
US60/647,366 2005-01-25
PCT/US2006/002875 WO2006081392A1 (en) 2005-01-25 2006-01-25 N-halogenated amino acids and n, n-dihalogenated amino acids in combination with hypohalous acids

Publications (3)

Publication Number Publication Date
JP2008531479A JP2008531479A (ja) 2008-08-14
JP2008531479A5 JP2008531479A5 (enExample) 2009-03-05
JP5329095B2 true JP5329095B2 (ja) 2013-10-30

Family

ID=36441417

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007553252A Expired - Fee Related JP5329095B2 (ja) 2005-01-25 2006-01-25 次亜ハロゲン酸と組み合わせる、ｎ−ハロゲン化アミノ酸およびｎ，ｎ−ジハロゲン化アミノ酸

Country Status (14)

Country Link
US (1) US7846971B2 (enExample)
EP (1) EP1896001B1 (enExample)
JP (1) JP5329095B2 (enExample)
KR (1) KR20070098947A (enExample)
CN (1) CN101132785A (enExample)
AU (1) AU2006208046B2 (enExample)
BR (1) BRPI0607302A2 (enExample)
CA (1) CA2595889C (enExample)
ES (1) ES2421157T3 (enExample)
IL (1) IL184771A (enExample)
MX (1) MX2007008928A (enExample)
TW (1) TWI386201B (enExample)
WO (1) WO2006081392A1 (enExample)
ZA (1) ZA200706402B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8764638B2 (en) 2008-10-17 2014-07-01 Al Medical Devices, Inc. Endotracheal intubation device
US9888832B2 (en) 2010-09-24 2018-02-13 Blink Device LLC Endotracheal intubation device

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1656095E (pt) * 2003-08-18 2014-03-11 Novabay Pharmaceuticals Inc Aminoácidos n,n-dihalogenados e seus derivados
US8747882B2 (en) 2005-04-21 2014-06-10 Astra Tech Ab Catheter assembly with bactericidal effect
WO2007035911A1 (en) * 2005-09-21 2007-03-29 Novabay Pharmaceuticals, Inc. System and method for the prevention and treatment of bacterial and fungal infections including urinary tract infections (uti) using a hypohalous acid compositions
JP2009511493A (ja) * 2005-10-06 2009-03-19 ノバベイ・ファーマシューティカルズ・インコーポレイテッド Ｎ−ハロゲン化アミノ酸を使用する、尿路感染症（ｕｔｉ）を含む細菌感染症および真菌感染症の予防のためのシステムおよび方法
TW200843787A (en) * 2006-12-29 2008-11-16 Novabay Pharmaceuticals Inc N-halogenated amino compounds and derivatives; compositions and methods of using them
EP2111252A4 (en) * 2007-01-31 2010-12-01 Adam Heller MANAGEMENT OF PAIN BY ELECTROCHEMICAL PATHWAY
UY31056A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Fromulaciones aminocido n-halogenado y metodos de limpieza y desinfeccion
UY31058A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado con compuestos antiinflamatorios
UY31057A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado que contiene acido alifatico
UY31059A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado
UY31055A1 (es) * 2008-02-01 2008-10-31 Alcon Res Ltd Sales antimicrobianas de aminoacido n-halogenado
JP2011516578A (ja) * 2008-04-10 2011-05-26 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 気管支肺感染症の治療および予防のための組成物および方法
CA2723262A1 (en) * 2008-04-15 2009-10-22 Waldemar Gottardi Compositions and devices for antisepsis and anticoagulation
IL192262A (en) * 2008-06-17 2016-05-31 Z H T Eng Equipment And Tech Ltd A polymer that releases drugs into the animal body, a medicinal product containing it and a method for its preparation
WO2010017405A1 (en) * 2008-08-06 2010-02-11 Adam Heller Methods and compositions for the treatment of pain
AU2009281998A1 (en) * 2008-08-12 2010-02-18 Novabay Pharmaceuticals, Inc. Antimicrobial gel formulations
WO2010054009A1 (en) * 2008-11-07 2010-05-14 Novabay Pharmaceuticals, Inc. Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions
JP5599808B2 (ja) 2008-11-07 2014-10-01 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 抗菌性ｎ−塩素化組成物
US20100204181A1 (en) * 2009-02-06 2010-08-12 Alcon Research, Ltd. N-halogenated amino acid formulations comprising phosphine or amine oxides
AU2010226794A1 (en) * 2009-03-18 2011-10-27 Olatec Industries Llc Compounds for treating inflammation and pain
US20100272783A1 (en) * 2009-04-24 2010-10-28 Novabay Pharmaceuticals, Inc. Methods of Treating Infections of the Nail
US20110020474A1 (en) * 2009-07-27 2011-01-27 Novabay Pharmaceuticals, Inc. Methods of Treating Infections of the Nail or Skin Using Hypohalite
SG182621A1 (en) * 2010-02-04 2012-08-30 Novabay Pharmaceuticals Inc Polysaccharide based antimicrobial formulations
TWI407907B (zh) 2010-10-04 2013-09-11 Far Eastern New Century Corp An antibacterial agent with water solubility and biodegradability
EP2720665A2 (en) 2011-06-15 2014-04-23 Rls Global Ab Detection and removal of carious dentin tissue.
SE536581C2 (sv) 2012-07-24 2014-03-11 Rls Global Ab Ett kit för behandling av sår eller liknande och ett preparat och metoder därav
DK3469117T3 (da) 2016-06-09 2022-02-28 De Nora Holdings Us Inc Elektrolytisk fremstilling af organiske chloraminopløsninger
EP3745861A1 (en) * 2018-01-30 2020-12-09 Buckman Laboratories International, Inc. Synergistic combinations of monochloramine and organic acid, and methods of using the same for microbial control
CN113729039A (zh) * 2021-08-27 2021-12-03 上海罗克环控节能科技股份有限公司 一种绿色环保消毒液及其制造方法
US12251486B2 (en) 2021-09-09 2025-03-18 Toyota Motor North America, Inc. Vehicle sanitizing systems and methods for using the same

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998945A (en) * 1972-06-12 1976-12-21 National Patent Development Corporation Dental treatment
US3950536A (en) * 1974-02-01 1976-04-13 Sol Joseph Barer N,N-Dichloro substituted aminocarboxylic acids as bactericides and fungicides
US4015008A (en) * 1974-02-01 1977-03-29 National Patent Development Corporation N,N-dichloro substituted aminocarboxylic acids as microbiocides
US3966796A (en) * 1974-06-14 1976-06-29 Interx Research Corporation N-chloro-amino acid derivatives activity
US4045578A (en) * 1974-06-14 1977-08-30 Interx Research Corporation N-chloro-amino acid derivatives exhibiting antibacterial activity
US4386103A (en) * 1981-01-30 1983-05-31 Merck & Co., Inc. Dichloroamino acid derivatives useful as potent germicidal and fungicidal agents
US5096700A (en) * 1990-09-28 1992-03-17 The Procter & Gamble Company Halogenated aminohexanoates and aminobutyrates antimicrobial agents
DE4041703C2 (de) 1990-12-24 1993-10-21 Waldemar Dr Gottardi Alkalimetallsalze des N-Chlortaurins in kristalliner Form, Verfahren zu deren Herstellung und deren Verwendung
JP3759757B2 (ja) * 1994-01-13 2006-03-29 相互薬工株式会社 殺菌剤
US5753701A (en) * 1996-10-25 1998-05-19 University Of Kentucky N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters as novel safe agents for water disinfection
DE19712565A1 (de) * 1997-03-25 1998-10-01 Thomas W Dr Stief Arzneimittel auf der Basis eines Singulett-Sauerstoff erzeugenden Agenzes
DE19816102C1 (de) * 1998-04-10 1999-09-16 Waldemar Gottardi Verfahren zum Inaktivieren von Viren in Proteinlösungen, Verwendung von N-Chlortaurin in dem Verfahren sowie nach dem Verfahren hergestellte Proteinlösungen
CA2320556A1 (en) 1999-09-29 2001-03-29 Queen's University At Kingston N,n-dichlorinated omega amino acids and uses thereof
ES2276818T3 (es) 2000-09-14 2007-07-01 Waldemar Gottardi Agente que contiene n-clorotaurina, asi como su uso para el tratamiento de polipos de la mucosa.
FR2819723B1 (fr) * 2001-01-23 2006-11-17 Arnaud Mainnemare Composition halogene, son procede de preparation et ses utilisations
WO2004003702A2 (en) * 2002-06-27 2004-01-08 Geranio Nicholas L Integrated property database and search engine
PT1656095E (pt) 2003-08-18 2014-03-11 Novabay Pharmaceuticals Inc Aminoácidos n,n-dihalogenados e seus derivados
JP2007514782A (ja) * 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法
TW200843787A (en) 2006-12-29 2008-11-16 Novabay Pharmaceuticals Inc N-halogenated amino compounds and derivatives; compositions and methods of using them

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8764638B2 (en) 2008-10-17 2014-07-01 Al Medical Devices, Inc. Endotracheal intubation device
US9750913B2 (en) 2008-10-17 2017-09-05 Centurion Medical Products Corporation Endotracheal intubation device
US9888832B2 (en) 2010-09-24 2018-02-13 Blink Device LLC Endotracheal intubation device

Also Published As

Publication number Publication date
AU2006208046A1 (en) 2006-08-03
BRPI0607302A2 (pt) 2009-08-25
IL184771A (en) 2013-04-30
TW200640445A (en) 2006-12-01
TWI386201B (zh) 2013-02-21
EP1896001A1 (en) 2008-03-12
US20060247209A1 (en) 2006-11-02
MX2007008928A (es) 2007-12-10
AU2006208046B2 (en) 2011-03-24
AU2006208046A2 (en) 2006-08-03
CN101132785A (zh) 2008-02-27
ZA200706402B (en) 2011-12-28
US7846971B2 (en) 2010-12-07
CA2595889C (en) 2013-11-19
JP2008531479A (ja) 2008-08-14
KR20070098947A (ko) 2007-10-05
ES2421157T3 (es) 2013-08-29
CA2595889A1 (en) 2006-08-03
EP1896001B1 (en) 2013-06-19
WO2006081392A1 (en) 2006-08-03
IL184771A0 (en) 2007-12-03

Similar Documents

Publication Publication Date Title
TWI386201B (zh) Ｎ-鹵化胺基酸、ｎ，ｎ-二鹵化胺基酸與其衍生物；以及使用其之組合物與方法
JP4994033B2 (ja) Ｎ，ｎ−ジハロゲン化アミノ酸および誘導体
JP5564264B2 (ja) Ｎ−ハロゲン化アミノ化合物および誘導体
WO2015153258A1 (en) Stable compositions of uncomplexed iodine and methods of use
US20250000900A1 (en) High molecular iodine concentration compositions, pharmaceutical formulations, preparation and uses
HK1117748A (en) N-halogenated amino acids and n, n-dihalogenated amino acids in combination with hypohalous acids
HK1103713B (en) N,n-dihalogenated amino acids and derivatives
RU2232711C1 (ru) Способ получения дифторида ксенона, способ его очистки от взрывоопасных примесей и его использование
Stawarz-Janeczek et al. Disinfectants Used in Stomatology and

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090116

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20090116

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20111206

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120306

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120313

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20120328

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20120404

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120502

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130129

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130423

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20130716

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20130724

R150 Certificate of patent or registration of utility model

Ref document number: 5329095

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees