AU2006208046B2 - N-halogenated amino acids and N, N-dihalogenated amino acids in combination with hypohalous acids - Google Patents

N-halogenated amino acids and N, N-dihalogenated amino acids in combination with hypohalous acids Download PDF

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Publication number
AU2006208046B2
AU2006208046B2 AU2006208046A AU2006208046A AU2006208046B2 AU 2006208046 B2 AU2006208046 B2 AU 2006208046B2 AU 2006208046 A AU2006208046 A AU 2006208046A AU 2006208046 A AU2006208046 A AU 2006208046A AU 2006208046 B2 AU2006208046 B2 AU 2006208046B2
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AU
Australia
Prior art keywords
acid
group
lower alkyl
derivative
hydrogen
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006208046A
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English (en)
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AU2006208046A1 (en
AU2006208046A2 (en
Inventor
Mansour Bassiri
Behzad Khosrovi
Ramin Najafi
Lu Wang
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Novabay Pharmaceuticals Inc
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Novabay Pharmaceuticals Inc
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Publication of AU2006208046A1 publication Critical patent/AU2006208046A1/en
Publication of AU2006208046A2 publication Critical patent/AU2006208046A2/en
Application granted granted Critical
Publication of AU2006208046B2 publication Critical patent/AU2006208046B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/16—Fluorine compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2006208046A 2005-01-25 2006-01-25 N-halogenated amino acids and N, N-dihalogenated amino acids in combination with hypohalous acids Ceased AU2006208046B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64736605P 2005-01-25 2005-01-25
US60/647,366 2005-01-25
PCT/US2006/002875 WO2006081392A1 (en) 2005-01-25 2006-01-25 N-halogenated amino acids and n, n-dihalogenated amino acids in combination with hypohalous acids

Publications (3)

Publication Number Publication Date
AU2006208046A1 AU2006208046A1 (en) 2006-08-03
AU2006208046A2 AU2006208046A2 (en) 2006-08-03
AU2006208046B2 true AU2006208046B2 (en) 2011-03-24

Family

ID=36441417

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006208046A Ceased AU2006208046B2 (en) 2005-01-25 2006-01-25 N-halogenated amino acids and N, N-dihalogenated amino acids in combination with hypohalous acids

Country Status (14)

Country Link
US (1) US7846971B2 (enExample)
EP (1) EP1896001B1 (enExample)
JP (1) JP5329095B2 (enExample)
KR (1) KR20070098947A (enExample)
CN (1) CN101132785A (enExample)
AU (1) AU2006208046B2 (enExample)
BR (1) BRPI0607302A2 (enExample)
CA (1) CA2595889C (enExample)
ES (1) ES2421157T3 (enExample)
IL (1) IL184771A (enExample)
MX (1) MX2007008928A (enExample)
TW (1) TWI386201B (enExample)
WO (1) WO2006081392A1 (enExample)
ZA (1) ZA200706402B (enExample)

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WO2007035911A1 (en) * 2005-09-21 2007-03-29 Novabay Pharmaceuticals, Inc. System and method for the prevention and treatment of bacterial and fungal infections including urinary tract infections (uti) using a hypohalous acid compositions
JP2009511493A (ja) * 2005-10-06 2009-03-19 ノバベイ・ファーマシューティカルズ・インコーポレイテッド Ｎ−ハロゲン化アミノ酸を使用する、尿路感染症（ｕｔｉ）を含む細菌感染症および真菌感染症の予防のためのシステムおよび方法
TW200843787A (en) * 2006-12-29 2008-11-16 Novabay Pharmaceuticals Inc N-halogenated amino compounds and derivatives; compositions and methods of using them
EP2111252A4 (en) * 2007-01-31 2010-12-01 Adam Heller MANAGEMENT OF PAIN BY ELECTROCHEMICAL PATHWAY
UY31056A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Fromulaciones aminocido n-halogenado y metodos de limpieza y desinfeccion
UY31058A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado con compuestos antiinflamatorios
UY31057A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado que contiene acido alifatico
UY31059A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado
UY31055A1 (es) * 2008-02-01 2008-10-31 Alcon Res Ltd Sales antimicrobianas de aminoacido n-halogenado
JP2011516578A (ja) * 2008-04-10 2011-05-26 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 気管支肺感染症の治療および予防のための組成物および方法
CA2723262A1 (en) * 2008-04-15 2009-10-22 Waldemar Gottardi Compositions and devices for antisepsis and anticoagulation
IL192262A (en) * 2008-06-17 2016-05-31 Z H T Eng Equipment And Tech Ltd A polymer that releases drugs into the animal body, a medicinal product containing it and a method for its preparation
WO2010017405A1 (en) * 2008-08-06 2010-02-11 Adam Heller Methods and compositions for the treatment of pain
AU2009281998A1 (en) * 2008-08-12 2010-02-18 Novabay Pharmaceuticals, Inc. Antimicrobial gel formulations
WO2010044862A1 (en) 2008-10-17 2010-04-22 Ai Medical Devices, Inc. Endotracheal intubation device
WO2010054009A1 (en) * 2008-11-07 2010-05-14 Novabay Pharmaceuticals, Inc. Antimicrobial oxazolidinone, hydantoin and imidazolidinone compositions
JP5599808B2 (ja) 2008-11-07 2014-10-01 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 抗菌性ｎ−塩素化組成物
US20100204181A1 (en) * 2009-02-06 2010-08-12 Alcon Research, Ltd. N-halogenated amino acid formulations comprising phosphine or amine oxides
AU2010226794A1 (en) * 2009-03-18 2011-10-27 Olatec Industries Llc Compounds for treating inflammation and pain
US20100272783A1 (en) * 2009-04-24 2010-10-28 Novabay Pharmaceuticals, Inc. Methods of Treating Infections of the Nail
US20110020474A1 (en) * 2009-07-27 2011-01-27 Novabay Pharmaceuticals, Inc. Methods of Treating Infections of the Nail or Skin Using Hypohalite
SG182621A1 (en) * 2010-02-04 2012-08-30 Novabay Pharmaceuticals Inc Polysaccharide based antimicrobial formulations
US9888832B2 (en) 2010-09-24 2018-02-13 Blink Device LLC Endotracheal intubation device
TWI407907B (zh) 2010-10-04 2013-09-11 Far Eastern New Century Corp An antibacterial agent with water solubility and biodegradability
EP2720665A2 (en) 2011-06-15 2014-04-23 Rls Global Ab Detection and removal of carious dentin tissue.
SE536581C2 (sv) 2012-07-24 2014-03-11 Rls Global Ab Ett kit för behandling av sår eller liknande och ett preparat och metoder därav
DK3469117T3 (da) 2016-06-09 2022-02-28 De Nora Holdings Us Inc Elektrolytisk fremstilling af organiske chloraminopløsninger
EP3745861A1 (en) * 2018-01-30 2020-12-09 Buckman Laboratories International, Inc. Synergistic combinations of monochloramine and organic acid, and methods of using the same for microbial control
CN113729039A (zh) * 2021-08-27 2021-12-03 上海罗克环控节能科技股份有限公司 一种绿色环保消毒液及其制造方法
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US3998945A (en) * 1972-06-12 1976-12-21 National Patent Development Corporation Dental treatment
DE4041703A1 (de) * 1990-12-24 1992-07-02 Waldemar Dr Gottardi Neue alkalisalze des n-chlortaurins
JPH07206609A (ja) * 1994-01-13 1995-08-08 Sogo Yatsukou Kk 殺菌剤
DE19712565A1 (de) * 1997-03-25 1998-10-01 Thomas W Dr Stief Arzneimittel auf der Basis eines Singulett-Sauerstoff erzeugenden Agenzes
DE19816102C1 (de) * 1998-04-10 1999-09-16 Waldemar Gottardi Verfahren zum Inaktivieren von Viren in Proteinlösungen, Verwendung von N-Chlortaurin in dem Verfahren sowie nach dem Verfahren hergestellte Proteinlösungen
WO2002058692A2 (fr) * 2001-01-23 2002-08-01 Arnaud Mainnemare Composition halogenee de hypohalites avec n-chloramine taurine, procede de preparation et ses utilisations
US20040002871A1 (en) * 2002-06-27 2004-01-01 Geranio Nicholas L. Integrated property database and search engine

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PT1656095E (pt) 2003-08-18 2014-03-11 Novabay Pharmaceuticals Inc Aminoácidos n,n-dihalogenados e seus derivados
JP2007514782A (ja) * 2003-12-17 2007-06-07 リブ−エックス ファーマシューティカルズ，インコーポレイテッド ハロゲン化ビアリール複素環式化合物ならびにその作製方法および使用方法
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US3998945A (en) * 1972-06-12 1976-12-21 National Patent Development Corporation Dental treatment
DE4041703A1 (de) * 1990-12-24 1992-07-02 Waldemar Dr Gottardi Neue alkalisalze des n-chlortaurins
JPH07206609A (ja) * 1994-01-13 1995-08-08 Sogo Yatsukou Kk 殺菌剤
DE19712565A1 (de) * 1997-03-25 1998-10-01 Thomas W Dr Stief Arzneimittel auf der Basis eines Singulett-Sauerstoff erzeugenden Agenzes
DE19816102C1 (de) * 1998-04-10 1999-09-16 Waldemar Gottardi Verfahren zum Inaktivieren von Viren in Proteinlösungen, Verwendung von N-Chlortaurin in dem Verfahren sowie nach dem Verfahren hergestellte Proteinlösungen
WO2002058692A2 (fr) * 2001-01-23 2002-08-01 Arnaud Mainnemare Composition halogenee de hypohalites avec n-chloramine taurine, procede de preparation et ses utilisations
US20040002871A1 (en) * 2002-06-27 2004-01-01 Geranio Nicholas L. Integrated property database and search engine

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Martineigh et al. J. Phys. Chem A 1998, 102, pp 9838-9846 *

Also Published As

Publication number Publication date
AU2006208046A1 (en) 2006-08-03
BRPI0607302A2 (pt) 2009-08-25
IL184771A (en) 2013-04-30
TW200640445A (en) 2006-12-01
JP5329095B2 (ja) 2013-10-30
TWI386201B (zh) 2013-02-21
EP1896001A1 (en) 2008-03-12
US20060247209A1 (en) 2006-11-02
MX2007008928A (es) 2007-12-10
AU2006208046A2 (en) 2006-08-03
CN101132785A (zh) 2008-02-27
ZA200706402B (en) 2011-12-28
US7846971B2 (en) 2010-12-07
CA2595889C (en) 2013-11-19
JP2008531479A (ja) 2008-08-14
KR20070098947A (ko) 2007-10-05
ES2421157T3 (es) 2013-08-29
CA2595889A1 (en) 2006-08-03
EP1896001B1 (en) 2013-06-19
WO2006081392A1 (en) 2006-08-03
IL184771A0 (en) 2007-12-03

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