JP5323014B2 - 液体試料の処理ユニットおよびその処理方法 - Google Patents
液体試料の処理ユニットおよびその処理方法 Download PDFInfo
- Publication number
- JP5323014B2 JP5323014B2 JP2010176299A JP2010176299A JP5323014B2 JP 5323014 B2 JP5323014 B2 JP 5323014B2 JP 2010176299 A JP2010176299 A JP 2010176299A JP 2010176299 A JP2010176299 A JP 2010176299A JP 5323014 B2 JP5323014 B2 JP 5323014B2
- Authority
- JP
- Japan
- Prior art keywords
- valve
- sample
- reagent
- path
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000012545 processing Methods 0.000 title claims abstract description 266
- 239000007788 liquid Substances 0.000 title claims abstract description 116
- 238000003672 processing method Methods 0.000 title description 2
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 462
- 238000006243 chemical reaction Methods 0.000 claims abstract description 179
- 239000012530 fluid Substances 0.000 claims description 189
- 238000002156 mixing Methods 0.000 claims description 85
- 238000004458 analytical method Methods 0.000 claims description 83
- 238000010790 dilution Methods 0.000 claims description 44
- 239000012895 dilution Substances 0.000 claims description 44
- 239000007795 chemical reaction product Substances 0.000 claims description 31
- 238000004891 communication Methods 0.000 claims description 12
- 238000007865 diluting Methods 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 35
- 239000000523 sample Substances 0.000 description 443
- 238000009826 distribution Methods 0.000 description 84
- 239000000203 mixture Substances 0.000 description 49
- 238000004140 cleaning Methods 0.000 description 36
- 210000004027 cell Anatomy 0.000 description 18
- 238000010586 diagram Methods 0.000 description 13
- 238000011534 incubation Methods 0.000 description 11
- 238000011068 loading method Methods 0.000 description 7
- 230000007246 mechanism Effects 0.000 description 7
- 239000011541 reaction mixture Substances 0.000 description 6
- 230000037361 pathway Effects 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 230000003252 repetitive effect Effects 0.000 description 5
- 239000003570 air Substances 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- 239000003085 diluting agent Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 238000010257 thawing Methods 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000002405 diagnostic procedure Methods 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 206010013710 Drug interaction Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 230000005679 Peltier effect Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000012080 ambient air Substances 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000003891 environmental analysis Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 230000037452 priming Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- 238000002562 urinalysis Methods 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1072—Multiple transfer devices with provision for selective pipetting of individual channels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/087—Multiple sequential chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/14—Means for pressure control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09167521.5 | 2009-08-07 | ||
| EP09167521A EP2311563A1 (en) | 2009-08-07 | 2009-08-07 | Processing units and methods for the processing of liquid samples |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011039051A JP2011039051A (ja) | 2011-02-24 |
| JP2011039051A5 JP2011039051A5 (https=) | 2012-10-18 |
| JP5323014B2 true JP5323014B2 (ja) | 2013-10-23 |
Family
ID=41667552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010176299A Expired - Fee Related JP5323014B2 (ja) | 2009-08-07 | 2010-08-05 | 液体試料の処理ユニットおよびその処理方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8778696B2 (https=) |
| EP (1) | EP2311563A1 (https=) |
| JP (1) | JP5323014B2 (https=) |
| CN (1) | CN101995479A (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2447875T3 (es) | 2007-10-02 | 2014-03-13 | Theranos, Inc. | Dispositivos modulares para punto de cuidados y usos de los mismos |
| EP3151015A1 (en) * | 2010-11-15 | 2017-04-05 | F. Hoffmann-La Roche AG | Instrument and method for the automated thermal treatment of liquid samples |
| EP4024029A3 (en) | 2011-01-21 | 2022-09-14 | Labrador Diagnostics LLC | Systems and methods for sample use maximization |
| US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
| US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
| US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
| US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
| US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
| EP2758510A4 (en) * | 2011-09-25 | 2015-05-06 | Theranos Inc | SYSTEMS AND METHOD FOR MULTILAYER ANALYSIS |
| US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
| US8663583B2 (en) * | 2011-12-27 | 2014-03-04 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
| RU2688746C2 (ru) * | 2014-06-05 | 2019-05-22 | Иллумина, Инк. | Системы и способы с использованием поворотного клапана для по меньшей мере одного из приготовления образца или анализа образца |
| GB201414247D0 (en) * | 2014-08-12 | 2014-09-24 | Cambsolv Ltd | Modular microfluidic device |
| GB2546233A (en) * | 2015-08-19 | 2017-07-19 | Cambsolv Ltd | Modular microfluidic device for analytical bioassay |
| CN105651767B (zh) * | 2015-12-29 | 2018-06-05 | 厦门大学 | 一种使用3d打印模具制备的即吸即测液体检测装置 |
| AU2017220028B2 (en) | 2016-02-17 | 2022-04-28 | Becton, Dickinson And Company | Automated sample preparation system for diagnostic testing of same |
| CA3019789C (en) | 2016-04-22 | 2025-11-18 | Becton, Dickinson And Company | AUTOMATED DIAGNOSTIC ANALYZER AND ITS OPERATING PROCESS |
| CN109073664B (zh) | 2016-04-22 | 2022-12-06 | 贝克顿·迪金森公司 | 自动诊断分析仪及其操作方法 |
| US11470908B2 (en) | 2017-02-27 | 2022-10-18 | Kornit Digital Technologies Ltd. | Articles of footwear and apparel having a three-dimensionally printed feature |
| US20190037961A1 (en) | 2017-02-27 | 2019-02-07 | Voxel8, Inc. | 3d-printed articles of footwear with property gradients |
| US11857023B2 (en) | 2017-02-27 | 2024-01-02 | Kornit Digital Technologies Ltd. | Digital molding and associated articles and methods |
| US11701813B2 (en) | 2017-02-27 | 2023-07-18 | Kornit Digital Technologies Ltd. | Methods for three-dimensionally printing and associated multi-input print heads and systems |
| EP3585620B1 (en) * | 2017-02-27 | 2024-05-15 | Kornit Digital Technologies Ltd. | 3d printing devices including mixing nozzles |
| US11904614B2 (en) | 2017-02-27 | 2024-02-20 | Kornit Digital Technologies Ltd. | Multi-input print heads for three-dimensionally printing and associated systems and methods |
| CN110106072B (zh) * | 2019-04-25 | 2022-05-13 | 珠海迪尔生物工程股份有限公司 | 一种微生物样品测试卡加样装置及加样方法 |
| WO2020227855A1 (zh) * | 2019-05-10 | 2020-11-19 | 深圳迈瑞生物医疗电子股份有限公司 | 样本检测装置和样本检测装置的运行方法 |
| CN111569967B (zh) * | 2020-06-24 | 2025-03-04 | 深圳市国赛生物技术有限公司 | 微流控芯片 |
| CN111830266B (zh) * | 2020-08-06 | 2024-12-17 | 浙江弘瑞医疗科技有限公司 | 一种试剂自动分配装置 |
| CN113390693A (zh) * | 2021-07-15 | 2021-09-14 | 北京凤栖桐科技有限公司 | 一种快速食品检测系统及其食品检测方法 |
| US12455227B2 (en) * | 2023-01-19 | 2025-10-28 | International Business Machines Corporation | Enclosed, multi-chamber metering and mixing system used for urinalysis |
| EP4616948A1 (en) * | 2024-03-14 | 2025-09-17 | Leica Microsystems CMS GmbH | Fluid dispenser for supplying a fluid to a microfluidic system and fluid container |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5159635A (en) * | 1990-07-09 | 1992-10-27 | Symbol Technologies, Inc. | System for encoding data in machine readable graphic form |
| US5638986A (en) | 1992-11-06 | 1997-06-17 | Fluilogic Systems Oy | Method and equipment for dosing small amounts of liquid quantitatively |
| JP2948069B2 (ja) * | 1993-09-20 | 1999-09-13 | 株式会社日立製作所 | 化学分析装置 |
| DK1179585T3 (da) * | 1997-12-24 | 2008-11-10 | Cepheid | Indretning og fremgangsmåde til lysis |
| US6290908B1 (en) | 1998-03-30 | 2001-09-18 | Hitachi, Ltd. | Water quality meter and water monitoring system |
| FI981432A7 (fi) | 1998-06-22 | 2000-01-14 | Niilo Kaartinen | Jäähana |
| US6878540B2 (en) * | 1999-06-25 | 2005-04-12 | Cepheid | Device for lysing cells, spores, or microorganisms |
| US20030091477A1 (en) * | 1999-12-22 | 2003-05-15 | Paul Eric A. | Flow-thru chip cartridge, chip holder, system & method thereof |
| DE10041853C1 (de) * | 2000-08-25 | 2002-02-28 | Gmd Gmbh | Konfigurierbares Mikroreaktornetzwerk |
| JP2002214241A (ja) * | 2000-11-20 | 2002-07-31 | Minolta Co Ltd | マイクロチップ |
| JP2002236131A (ja) * | 2000-12-08 | 2002-08-23 | Minolta Co Ltd | マイクロチップ |
| JP3538777B2 (ja) | 2001-03-26 | 2004-06-14 | 独立行政法人産業技術総合研究所 | 微小化学反応装置 |
| US6557575B1 (en) * | 2001-11-19 | 2003-05-06 | Waters Investments Limited | Fluid flow control freeze/thaw valve for narrow bore capillaries or microfluidic devices |
| JP2003190751A (ja) * | 2001-12-25 | 2003-07-08 | Minolta Co Ltd | 混合方法、混合装置、及び該混合装置を用いた検査装置 |
| US7244961B2 (en) * | 2002-08-02 | 2007-07-17 | Silicon Valley Scientific | Integrated system with modular microfluidic components |
| DE10322942A1 (de) * | 2003-05-19 | 2004-12-09 | Hans-Knöll-Institut für Naturstoff-Forschung e.V. | Vorrichtung zum Positionieren und Ausschleusen von in Separationsmedium eingebetteten Fluidkompartimenten |
| US20050095602A1 (en) | 2003-11-04 | 2005-05-05 | West Jason A. | Microfluidic integrated microarrays for biological detection |
| JP4455014B2 (ja) * | 2003-11-07 | 2010-04-21 | セイコーインスツル株式会社 | 検査用マイクロチップおよび検査装置と検査方法 |
| JP4344859B2 (ja) * | 2004-01-09 | 2009-10-14 | 東亜ディーケーケー株式会社 | 液体供給モジュール及びこれを用いた分析装置 |
| US7887750B2 (en) * | 2004-05-05 | 2011-02-15 | Bayer Healthcare Llc | Analytical systems, devices, and cartridges therefor |
| JP4701757B2 (ja) | 2005-03-10 | 2011-06-15 | 凸版印刷株式会社 | マイクロチャネルチップ |
| WO2006110097A1 (en) | 2005-04-14 | 2006-10-19 | Gyros Patent Ab | Separation structure |
| US20080131327A1 (en) | 2006-09-28 | 2008-06-05 | California Institute Of Technology | System and method for interfacing with a microfluidic chip |
| JP2008151770A (ja) * | 2006-11-22 | 2008-07-03 | Fujifilm Corp | マイクロ流路チップ |
| WO2008089767A1 (en) | 2007-01-26 | 2008-07-31 | Diramo A/S | Stacking of optic sensor and microfluidic-chips with optically communication through windows |
| KR101278154B1 (ko) | 2007-04-16 | 2013-06-27 | 삼성전자주식회사 | 원심력 기반의 미세유동 장치, 이를 구비한 미세유동시스템 및, 상기 미세유동 장치의 홈 위치 결정 방법 |
-
2009
- 2009-08-07 EP EP09167521A patent/EP2311563A1/en not_active Withdrawn
-
2010
- 2010-08-05 US US12/850,949 patent/US8778696B2/en not_active Expired - Fee Related
- 2010-08-05 JP JP2010176299A patent/JP5323014B2/ja not_active Expired - Fee Related
- 2010-08-06 CN CN2010102492233A patent/CN101995479A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2311563A1 (en) | 2011-04-20 |
| US20110189785A1 (en) | 2011-08-04 |
| US8778696B2 (en) | 2014-07-15 |
| CN101995479A (zh) | 2011-03-30 |
| JP2011039051A (ja) | 2011-02-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5323014B2 (ja) | 液体試料の処理ユニットおよびその処理方法 | |
| JP5395011B2 (ja) | 液体試料の分析システム | |
| CN108704677B (zh) | 一种微流控芯片及含其的分析仪器 | |
| CN108519373B (zh) | 一种化学发光微流控芯片及含其的分析仪器 | |
| CN108139418B (zh) | 受试体处理芯片、受试体处理装置及受试体处理方法 | |
| US20020071788A1 (en) | Microchip | |
| US9592509B2 (en) | Flow passage device and method of transporting liquid using the same | |
| CN108761055B (zh) | 一种微流控芯片及具有该微流控芯片的分析仪器 | |
| JPH03135768A (ja) | 分析法及び自動分析装置 | |
| JPH0437952B2 (https=) | ||
| WO2006132211A1 (ja) | 自動分析装置 | |
| JPWO2017061620A1 (ja) | 検体処理チップ、検体処理装置および検体処理方法 | |
| CN108716938B (zh) | 一种液体定量装置及其应用 | |
| CN106226540A (zh) | 全自动蛋白质芯片分析仪 | |
| CN111948409B (zh) | 一种微流控测试卡、测试卡组件、设备及控制方法 | |
| JP2009097999A (ja) | 検査装置 | |
| JP2009222479A (ja) | 検査装置 | |
| CN111812343B (zh) | 一种基于免疫比浊法测量的液路系统及其控制方法 | |
| JP2005318834A (ja) | オンライン化学反応装置 | |
| WO2009113487A1 (ja) | マイクロ検査チップおよびマイクロ検査チップの液体分割方法 | |
| KR101614333B1 (ko) | 미세유체 혼합장치 | |
| US20230143259A1 (en) | Automatic analyzing apparatus | |
| JP5182368B2 (ja) | マイクロ検査チップ、検査装置およびマイクロ検査チップの駆動方法 | |
| CN119534881A (zh) | 样本分析系统及方法 | |
| JP2006284322A (ja) | マイクロ総合分析システム |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20120903 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20120903 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20130117 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130129 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130426 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20130604 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20130612 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20130702 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20130716 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |