JP5281888B2 - 呼吸の神経制御を行うシステム - Google Patents

呼吸の神経制御を行うシステム Download PDF

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Publication number
JP5281888B2
JP5281888B2 JP2008516905A JP2008516905A JP5281888B2 JP 5281888 B2 JP5281888 B2 JP 5281888B2 JP 2008516905 A JP2008516905 A JP 2008516905A JP 2008516905 A JP2008516905 A JP 2008516905A JP 5281888 B2 JP5281888 B2 JP 5281888B2
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neural
sensor
respiratory disease
monitor
central respiratory
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JP2008543429A5 (enExample
JP2008543429A (ja
Inventor
キャパルソ，アンソニー・ヴイ
リバス，イマド
ブルック，エム・ジェイソン
リー，ケント
クウォック，ジョナサン
プ，ヤチュアン
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カーディアック ペースメイカーズ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3601—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114—Cardiac control, e.g. by vagal stimulation

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  • Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Electrical Control Of Air Or Fuel Supplied To Internal-Combustion Engine (AREA)
  • Feedback Control In General (AREA)
  • Control Of Eletrric Generators (AREA)
JP2008516905A 2005-06-13 2006-06-01 呼吸の神経制御を行うシステム Expired - Fee Related JP5281888B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/151,122 US8036750B2 (en) 2005-06-13 2005-06-13 System for neural control of respiration
US11/151,122 2005-06-13
PCT/US2006/021323 WO2006138069A1 (en) 2005-06-13 2006-06-01 System for neural control of respiration

Publications (3)

Publication Number Publication Date
JP2008543429A JP2008543429A (ja) 2008-12-04
JP2008543429A5 JP2008543429A5 (enExample) 2009-07-09
JP5281888B2 true JP5281888B2 (ja) 2013-09-04

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JP2008516905A Expired - Fee Related JP5281888B2 (ja) 2005-06-13 2006-06-01 呼吸の神経制御を行うシステム

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US (3) US8036750B2 (enExample)
EP (2) EP1899004B1 (enExample)
JP (1) JP5281888B2 (enExample)
AT (1) ATE501754T1 (enExample)
DE (1) DE602006020725D1 (enExample)
WO (1) WO2006138069A1 (enExample)

Families Citing this family (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
US8160711B2 (en) 2003-10-15 2012-04-17 Rmx, Llc Multimode device and method for controlling breathing
US9259573B2 (en) 2003-10-15 2016-02-16 Rmx, Llc Device and method for manipulating exhalation
US7979128B2 (en) 2003-10-15 2011-07-12 Rmx, Llc Device and method for gradually controlling breathing
US7970475B2 (en) 2003-10-15 2011-06-28 Rmx, Llc Device and method for biasing lung volume
US8467876B2 (en) 2003-10-15 2013-06-18 Rmx, Llc Breathing disorder detection and therapy delivery device and method
US8265759B2 (en) 2003-10-15 2012-09-11 Rmx, Llc Device and method for treating disorders of the cardiovascular system or heart
US8244358B2 (en) * 2003-10-15 2012-08-14 Rmx, Llc Device and method for treating obstructive sleep apnea
US8140164B2 (en) 2003-10-15 2012-03-20 Rmx, Llc Therapeutic diaphragm stimulation device and method
US7783353B2 (en) 2003-12-24 2010-08-24 Cardiac Pacemakers, Inc. Automatic neural stimulation modulation based on activity and circadian rhythm
US7460906B2 (en) 2003-12-24 2008-12-02 Cardiac Pacemakers, Inc. Baroreflex stimulation to treat acute myocardial infarction
US9020595B2 (en) 2003-12-24 2015-04-28 Cardiac Pacemakers, Inc. Baroreflex activation therapy with conditional shut off
US7486991B2 (en) 2003-12-24 2009-02-03 Cardiac Pacemakers, Inc. Baroreflex modulation to gradually decrease blood pressure
US7869881B2 (en) 2003-12-24 2011-01-11 Cardiac Pacemakers, Inc. Baroreflex stimulator with integrated pressure sensor
US8200331B2 (en) 2004-11-04 2012-06-12 Cardiac Pacemakers, Inc. System and method for filtering neural stimulation
US8126560B2 (en) 2003-12-24 2012-02-28 Cardiac Pacemakers, Inc. Stimulation lead for stimulating the baroreceptors in the pulmonary artery
US8024050B2 (en) 2003-12-24 2011-09-20 Cardiac Pacemakers, Inc. Lead for stimulating the baroreceptors in the pulmonary artery
US7706884B2 (en) 2003-12-24 2010-04-27 Cardiac Pacemakers, Inc. Baroreflex stimulation synchronized to circadian rhythm
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
EP2298410B1 (en) 2004-12-27 2013-10-09 The Feinstein Institute for Medical Research Treating inflammatory disorders by electrical vagus nerve stimulation
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
US7660628B2 (en) 2005-03-23 2010-02-09 Cardiac Pacemakers, Inc. System to provide myocardial and neural stimulation
US7499748B2 (en) 2005-04-11 2009-03-03 Cardiac Pacemakers, Inc. Transvascular neural stimulation device
US8036750B2 (en) 2005-06-13 2011-10-11 Cardiac Pacemakers, Inc. System for neural control of respiration
US20070044669A1 (en) * 2005-08-24 2007-03-01 Geise Gregory D Aluminum can compacting mechanism with improved actuation handle assembly
US9050005B2 (en) 2005-08-25 2015-06-09 Synapse Biomedical, Inc. Method and apparatus for transgastric neurostimulation
US7616990B2 (en) 2005-10-24 2009-11-10 Cardiac Pacemakers, Inc. Implantable and rechargeable neural stimulator
AU2006320444A1 (en) * 2005-12-02 2007-06-07 Synapse Biomedical, Inc. Transvisceral neurostimulation mapping device and method
US8676323B2 (en) 2006-03-09 2014-03-18 Synapse Biomedical, Inc. Ventilatory assist system and methods to improve respiratory function
US8457734B2 (en) 2006-08-29 2013-06-04 Cardiac Pacemakers, Inc. System and method for neural stimulation
US8121692B2 (en) 2006-08-30 2012-02-21 Cardiac Pacemakers, Inc. Method and apparatus for neural stimulation with respiratory feedback
US8050765B2 (en) 2006-08-30 2011-11-01 Cardiac Pacemakers, Inc. Method and apparatus for controlling neural stimulation during disordered breathing
US8280513B2 (en) 2006-12-22 2012-10-02 Rmx, Llc Device and method to treat flow limitations
ES2430613T3 (es) 2007-01-29 2013-11-21 Simon Fraser University Aparato de neuroestimulación transvascular
WO2008098001A2 (en) 2007-02-05 2008-08-14 Synapse Biomedical, Inc. Removable intramuscular electrode
WO2008123903A1 (en) * 2007-02-09 2008-10-16 Mayo Foundation For Medical Education And Research Peripheral oxistimulator apparatus and methods
US8406877B2 (en) * 2007-03-19 2013-03-26 Cardiac Pacemakers, Inc. Selective nerve stimulation with optionally closed-loop capabilities
US9820671B2 (en) 2007-05-17 2017-11-21 Synapse Biomedical, Inc. Devices and methods for assessing motor point electromyogram as a biomarker
US8983609B2 (en) 2007-05-30 2015-03-17 The Cleveland Clinic Foundation Apparatus and method for treating pulmonary conditions
US8630704B2 (en) 2007-06-25 2014-01-14 Cardiac Pacemakers, Inc. Neural stimulation with respiratory rhythm management
US8391970B2 (en) 2007-08-27 2013-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
US8478412B2 (en) 2007-10-30 2013-07-02 Synapse Biomedical, Inc. Method of improving sleep disordered breathing
US8428726B2 (en) 2007-10-30 2013-04-23 Synapse Biomedical, Inc. Device and method of neuromodulation to effect a functionally restorative adaption of the neuromuscular system
US8155744B2 (en) 2007-12-13 2012-04-10 The Cleveland Clinic Foundation Neuromodulatory methods for treating pulmonary disorders
US7848816B1 (en) * 2007-12-27 2010-12-07 Pacesetter, Inc. Acquiring nerve activity from carotid body and/or sinus
US7949398B1 (en) * 2007-12-27 2011-05-24 Pacesetter, Inc. Acquiring nerve activity from carotid body and/or sinus
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
WO2009146030A1 (en) 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of t-cell activity
US8579794B2 (en) * 2008-05-02 2013-11-12 Dymedix Corporation Agitator to stimulate the central nervous system
WO2010019481A1 (en) * 2008-08-11 2010-02-18 Conceptx Medical, Inc. Systems and methods for treating dyspnea, including via electrical afferent signal blocking
US8834347B2 (en) 2008-08-22 2014-09-16 Dymedix Corporation Anti-habituating sleep therapy for a closed loop neuromodulator
ES2452484T3 (es) 2008-11-18 2014-04-01 Setpoint Medical Corporation Dispositivos para optimizar la colocación de electrodos para la estimulación antiinflamatoria
WO2010059839A2 (en) * 2008-11-19 2010-05-27 Inspire Medical Systems, Inc. Method of treating sleep disordered breathing
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
CN102573986B (zh) 2009-06-09 2016-01-20 赛博恩特医疗器械公司 用于无导线刺激器的具有袋部的神经封套
US9072899B1 (en) 2009-09-04 2015-07-07 Todd Nickloes Diaphragm pacemaker
WO2014169145A1 (en) * 2013-04-10 2014-10-16 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
EP2515996B1 (en) 2009-12-23 2019-09-18 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
JP2011156175A (ja) * 2010-02-01 2011-08-18 Terumo Corp 電気刺激装置
JP2011160893A (ja) * 2010-02-05 2011-08-25 Terumo Corp 電気刺激装置
JP5769036B2 (ja) 2010-06-03 2015-08-26 カーディアック ペースメイカーズ， インコーポレイテッド 空間選択的迷走神経刺激のためのシステム
EP2661307A4 (en) 2011-01-03 2014-08-06 Univ California HIGH-DENSITY EPIDURAL STIMULATION TO FACILITATE MOVEMENTS, ATTACHMENTS, ARBITRARY MOVEMENTS AND RECOVERY OF AUTONOMIC, SEXUAL, VASOMOTORIC AND COGNITIVE FUNCTIONS AFTER NEUROLOGICAL INJURIES
EP2707094B1 (en) 2011-05-09 2016-02-03 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US12172017B2 (en) 2011-05-09 2024-12-24 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
US8983611B2 (en) 2011-09-27 2015-03-17 Cardiac Pacemakers, Inc. Neural control of central sleep apnea
CN104220128B (zh) 2011-11-11 2016-12-07 神经赋能科技公司 使运动功能、感觉功能、自主神经功能、性功能、血管舒缩功能和认知功能能够恢复的非侵入神经调节装置
ES2421055B1 (es) * 2012-01-24 2014-12-17 Tequir S.L. Sistema para el tratamiento de la escoliosis idiopática
AU2013230648B2 (en) 2012-03-05 2017-06-15 Lungpacer Medical Inc. Transvascular nerve stimulation apparatus and methods
AU2013230776B2 (en) 2012-03-08 2015-12-03 Medtronic Af Luxembourg S.A.R.L. Immune system neuromodulation and associated systems and methods
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
EP2840993A4 (en) 2012-04-24 2016-03-30 Cibiem Inc ENDOVASCULAR CATHETERS AND METHOD FOR CAROTID BODY ABLATION
WO2013181660A1 (en) 2012-06-01 2013-12-05 Cibiem, Inc. Methods and devices for cryogenic carotid body ablation
US9398930B2 (en) 2012-06-01 2016-07-26 Cibiem, Inc. Percutaneous methods and devices for carotid body ablation
US10736515B2 (en) * 2012-06-07 2020-08-11 Clarkson University Portable monitoring device for breath detection
EP4233953A3 (en) 2012-06-21 2023-11-01 Lungpacer Medical Inc. Transvascular diaphragm pacing systems
US9283033B2 (en) 2012-06-30 2016-03-15 Cibiem, Inc. Carotid body ablation via directed energy
WO2014144785A1 (en) 2013-03-15 2014-09-18 The Regents Of The University Of California Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion
US9610444B2 (en) 2013-03-15 2017-04-04 Pacesetter, Inc. Erythropoeitin production by electrical stimulation
EP3782698A1 (en) 2013-09-27 2021-02-24 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re- enable volitional control of hand function in tetraplegic subjects
EP3071285B1 (en) 2013-11-22 2020-06-03 Lungpacer Medical Inc. Apparatus for assisted breathing by transvascular nerve stimulation
EP3096835B1 (en) 2014-01-21 2019-08-07 Lungpacer Medical Inc. Systems for optimization of multi-electrode nerve pacing
WO2015138795A1 (en) 2014-03-12 2015-09-17 Cibiem, Inc. Carotid body ablation with a transvenous ultrasound imaging and ablation catheter
US9586048B2 (en) 2014-04-04 2017-03-07 Cardiac Pacemakers, Inc. Methods and apparatus for apnea therapy stimulation
US9402563B2 (en) 2014-04-04 2016-08-02 Cardiac Pacemakers, Inc. Discrimination of apnea type by medical device
WO2016033245A1 (en) 2014-08-26 2016-03-03 Rmx, Llc Devices and methods for reducing intrathoracic pressure
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
AU2015358385B2 (en) 2014-12-03 2020-09-03 Medtronic Ireland Manufacturing Unlimited Company Systems and methods for modulating nerves or other tissue
WO2016120074A1 (en) * 2015-01-28 2016-08-04 Koninklijke Philips N.V. Device and method for determining and/or monitoring the respiratory effort of a subject
WO2016126807A1 (en) 2015-02-03 2016-08-11 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
EP3322477B1 (en) * 2015-07-13 2025-12-10 The Regents of the University of California Accessing spinal network to enable respiratory function
CN108135535B (zh) 2015-08-11 2021-01-05 皇家飞利浦有限公司 用于处理与呼吸活动有关的肌电图信号的装置和方法
US11298533B2 (en) 2015-08-26 2022-04-12 The Regents Of The University Of California Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject
US11097122B2 (en) 2015-11-04 2021-08-24 The Regents Of The University Of California Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
EP3405255B1 (en) 2016-01-20 2025-12-31 Setpoint Medical Corporation IMPLANTABLE MICROSTIMULATORS AND INDUCTION CHARGING SYSTEMS
WO2017127756A1 (en) 2016-01-20 2017-07-27 Setpoint Medical Corporation Control of vagal stimulation
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US10524859B2 (en) 2016-06-07 2020-01-07 Metavention, Inc. Therapeutic tissue modulation devices and methods
US11399770B2 (en) * 2016-08-01 2022-08-02 Med-El Elektromedizinische Geraete Gmbh Respiratory triggered parasternal electromyographic recording in neurostimulators
EP4473909A3 (en) 2017-02-17 2025-01-29 The University of British Columbia Apparatus and methods for maintaining physiological functions
US12434068B2 (en) 2017-05-23 2025-10-07 The Regents Of The University Of California Accessing spinal networks to address sexual dysfunction
US10293164B2 (en) 2017-05-26 2019-05-21 Lungpacer Medical Inc. Apparatus and methods for assisted breathing by transvascular nerve stimulation
CN111163834A (zh) 2017-06-30 2020-05-15 隆佩瑟尔医疗公司 用于预防、减轻和/或治疗认知损伤的装置
EP3974021B1 (en) 2017-06-30 2023-06-14 ONWARD Medical N.V. A system for neuromodulation
US10195429B1 (en) 2017-08-02 2019-02-05 Lungpacer Medical Inc. Systems and methods for intravascular catheter positioning and/or nerve stimulation
US10940308B2 (en) 2017-08-04 2021-03-09 Lungpacer Medical Inc. Systems and methods for trans-esophageal sympathetic ganglion recruitment
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
KR102495358B1 (ko) 2017-09-25 2023-02-02 삼성전자주식회사 신경모방 자극 장치 및 그 방법
US12357828B2 (en) 2017-12-05 2025-07-15 Ecole Polytechnique Federale De Lausanne (Epfl) System for planning and/or providing neuromodulation
US11992684B2 (en) 2017-12-05 2024-05-28 Ecole Polytechnique Federale De Lausanne (Epfl) System for planning and/or providing neuromodulation
US20190175908A1 (en) 2017-12-11 2019-06-13 Lungpacer Medical Inc. Systems and methods for strengthening a respiratory muscle
WO2020041633A1 (en) 2018-08-23 2020-02-27 The Regents Of The University Of California Non-invasive spinal cord stimulation for nerve root palsy, cauda equina syndrome, and restoration of upper extremity function
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
WO2020097331A1 (en) 2018-11-08 2020-05-14 Lungpacer Medical Inc. Stimulation systems and related user interfaces
DE18205821T1 (de) 2018-11-13 2020-12-24 Gtx Medical B.V. Steuerungssystem zur bewegungsrekonstruktion und/oder wiederherstellung für einen patienten
US11471683B2 (en) 2019-01-29 2022-10-18 Synapse Biomedical, Inc. Systems and methods for treating sleep apnea using neuromodulation
EP3695878B1 (en) 2019-02-12 2023-04-19 ONWARD Medical N.V. A system for neuromodulation
WO2020210786A1 (en) 2019-04-12 2020-10-15 Setpoint Medical Corporation Vagus nerve stimulation to treat neurodegenerative disorders
WO2020232333A1 (en) 2019-05-16 2020-11-19 Lungpacer Medical Inc. Systems and methods for sensing and stimulation
CN114144226A (zh) 2019-05-22 2022-03-04 加利福尼亚大学董事会 经皮脊髓电神经调制器及其用途
US11771900B2 (en) 2019-06-12 2023-10-03 Lungpacer Medical Inc. Circuitry for medical stimulation systems
US11266838B1 (en) 2019-06-21 2022-03-08 Rmx, Llc Airway diagnostics utilizing phrenic nerve stimulation device and method
EP3824948A1 (en) 2019-11-19 2021-05-26 ONWARD Medical B.V. A planning and/or control system for a neuromodulation system
EP3827875B1 (en) 2019-11-27 2023-07-05 ONWARD Medical N.V. Neuromodulation system
DE19211698T1 (de) 2019-11-27 2021-09-02 Onward Medical B.V. Neuromodulation system
JP2023512447A (ja) 2020-01-13 2023-03-27 ザ ファインスタイン インスティチューツ フォー メディカル リサーチ 脾臓への高密度集束超音波刺激による出血及び出血性疾患の治療
KR20230012585A (ko) 2020-05-21 2023-01-26 더 파인스타인 인스티튜츠 포 메디칼 리서치 미주 신경 자극을 위한 시스템들 및 방법들
US12409328B1 (en) 2021-04-07 2025-09-09 Board Of Regents, The University Of Texas System Hypoglossal nerve stimulation
US12444497B2 (en) 2021-05-17 2025-10-14 Setpoint Medical Corporation Neurostimulation parameter authentication and expiration system for neurostimulation
US20240350805A1 (en) * 2021-08-25 2024-10-24 Vanderbilt University Systems and methods of improving sleep disordered breathing
US20250229086A1 (en) 2022-01-20 2025-07-17 Setpoint Medical Corporation Treatment of inflammatory disorders
US12649059B2 (en) 2022-08-05 2026-06-09 The Feinstein Institutes For Medical Research Methods for reducing bleeding in hemophilia by vagus nerve stimulation to prime platelets
US12623080B2 (en) 2023-06-21 2026-05-12 Onward Medical N.V. Neuromodulation system
WO2025245482A1 (en) * 2024-05-24 2025-11-27 Inspire Medical Systems, Inc. Stimulating target tissue among a set of target tissues for sleep disordered breathing (sdb) care

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5146918A (en) * 1991-03-19 1992-09-15 Medtronic, Inc. Demand apnea control of central and obstructive sleep apnea
US5546952A (en) 1994-09-21 1996-08-20 Medtronic, Inc. Method and apparatus for detection of a respiratory waveform
US5549655A (en) 1994-09-21 1996-08-27 Medtronic, Inc. Method and apparatus for synchronized treatment of obstructive sleep apnea
US5522862A (en) 1994-09-21 1996-06-04 Medtronic, Inc. Method and apparatus for treating obstructive sleep apnea
US5540733A (en) 1994-09-21 1996-07-30 Medtronic, Inc. Method and apparatus for detecting and treating obstructive sleep apnea
US5485851A (en) 1994-09-21 1996-01-23 Medtronic, Inc. Method and apparatus for arousal detection
US5483969A (en) 1994-09-21 1996-01-16 Medtronic, Inc. Method and apparatus for providing a respiratory effort waveform for the treatment of obstructive sleep apnea
US5540734A (en) * 1994-09-28 1996-07-30 Zabara; Jacob Cranial nerve stimulation treatments using neurocybernetic prosthesis
WO2000006249A2 (en) * 1998-07-27 2000-02-10 Case Western Reserve University Method and apparatus for closed-loop stimulation of the hypoglossal nerve in human patients to treat obstructive sleep apnea
US6748275B2 (en) 1999-05-05 2004-06-08 Respironics, Inc. Vestibular stimulation system and method
US6415183B1 (en) 1999-12-09 2002-07-02 Cardiac Pacemakers, Inc. Method and apparatus for diaphragmatic pacing
US6633779B1 (en) * 2000-11-27 2003-10-14 Science Medicus, Inc. Treatment of asthma and respiratory disease by means of electrical neuro-receptive waveforms
US20030195571A1 (en) * 2002-04-12 2003-10-16 Burnes John E. Method and apparatus for the treatment of central sleep apnea using biventricular pacing
US20030216789A1 (en) 2002-05-14 2003-11-20 The Foundry, Inc. Method and system for treating sleep apnea
SE0202537D0 (sv) 2002-08-28 2002-08-28 Siemens Elema Ab Nervstimuleringsapparat
US7092755B2 (en) * 2003-03-18 2006-08-15 Pacesetter, Inc. System and method of cardiac pacing during sleep apnea
US7155278B2 (en) * 2003-04-21 2006-12-26 Medtronic, Inc. Neurostimulation to treat effects of sleep apnea
US7591265B2 (en) 2003-09-18 2009-09-22 Cardiac Pacemakers, Inc. Coordinated use of respiratory and cardiac therapies for sleep disordered breathing
US7680537B2 (en) * 2003-08-18 2010-03-16 Cardiac Pacemakers, Inc. Therapy triggered by prediction of disordered breathing
US8140164B2 (en) * 2003-10-15 2012-03-20 Rmx, Llc Therapeutic diaphragm stimulation device and method
US8467876B2 (en) * 2003-10-15 2013-06-18 Rmx, Llc Breathing disorder detection and therapy delivery device and method
US7680538B2 (en) * 2005-03-31 2010-03-16 Case Western Reserve University Method of treating obstructive sleep apnea using electrical nerve stimulation
US8036750B2 (en) 2005-06-13 2011-10-11 Cardiac Pacemakers, Inc. System for neural control of respiration

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US8401651B2 (en) 2013-03-19
US8560072B2 (en) 2013-10-15
EP1899004B1 (en) 2011-03-16
DE602006020725D1 (de) 2011-04-28
US20060282131A1 (en) 2006-12-14
EP2277587A1 (en) 2011-01-26
US8036750B2 (en) 2011-10-11
US20110319959A1 (en) 2011-12-29
US20120323292A1 (en) 2012-12-20
ATE501754T1 (de) 2011-04-15
JP2008543429A (ja) 2008-12-04
WO2006138069A1 (en) 2006-12-28
EP1899004A1 (en) 2008-03-19

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