JP5260873B2 - カラルマ抽出物の製造方法および使用 - Google Patents
カラルマ抽出物の製造方法および使用 Download PDFInfo
- Publication number
- JP5260873B2 JP5260873B2 JP2006508488A JP2006508488A JP5260873B2 JP 5260873 B2 JP5260873 B2 JP 5260873B2 JP 2006508488 A JP2006508488 A JP 2006508488A JP 2006508488 A JP2006508488 A JP 2006508488A JP 5260873 B2 JP5260873 B2 JP 5260873B2
- Authority
- JP
- Japan
- Prior art keywords
- extract
- solvent
- karaluma
- resin
- extraction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000284 extract Substances 0.000 title claims description 175
- 238000004519 manufacturing process Methods 0.000 title claims description 7
- 229930182470 glycoside Natural products 0.000 claims description 119
- 239000002904 solvent Substances 0.000 claims description 117
- 238000000034 method Methods 0.000 claims description 107
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 76
- 239000011347 resin Substances 0.000 claims description 69
- 229920005989 resin Polymers 0.000 claims description 69
- 239000000463 material Substances 0.000 claims description 68
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 60
- 230000008569 process Effects 0.000 claims description 60
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 52
- 241000894007 species Species 0.000 claims description 40
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- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 15
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- JWMFYGXQPXQEEM-WZBAXQLOSA-N pregnane group Chemical group [C@@H]12CC[C@H](CC)[C@@]1(C)CC[C@H]1[C@H]2CCC2CCCC[C@]12C JWMFYGXQPXQEEM-WZBAXQLOSA-N 0.000 description 2
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P33/00—Antiparasitic agents
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- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Cardiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Toxicology (AREA)
- Nutrition Science (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN451/MAS/2003 | 2003-06-04 | ||
| IN451CH2003 | 2003-06-04 | ||
| PCT/IN2004/000150 WO2004108148A1 (en) | 2003-06-04 | 2004-05-31 | Processes for making caralluma extracts and uses |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012256942A Division JP2013067638A (ja) | 2003-06-04 | 2012-11-22 | カラルマ抽出物の製造方法および使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006526615A JP2006526615A (ja) | 2006-11-24 |
| JP2006526615A5 JP2006526615A5 (enExample) | 2007-07-26 |
| JP5260873B2 true JP5260873B2 (ja) | 2013-08-14 |
Family
ID=36011983
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006508488A Expired - Lifetime JP5260873B2 (ja) | 2003-06-04 | 2004-05-31 | カラルマ抽出物の製造方法および使用 |
| JP2012256942A Pending JP2013067638A (ja) | 2003-06-04 | 2012-11-22 | カラルマ抽出物の製造方法および使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012256942A Pending JP2013067638A (ja) | 2003-06-04 | 2012-11-22 | カラルマ抽出物の製造方法および使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7060308B2 (enExample) |
| EP (1) | EP1644013A1 (enExample) |
| JP (2) | JP5260873B2 (enExample) |
| KR (2) | KR20060034229A (enExample) |
| CN (1) | CN1798566B (enExample) |
| AU (2) | AU2004244850B2 (enExample) |
| BR (1) | BRPI0411400A (enExample) |
| CA (1) | CA2527702C (enExample) |
| CO (1) | CO5660269A2 (enExample) |
| NZ (2) | NZ543995A (enExample) |
| WO (1) | WO2004108148A1 (enExample) |
| ZA (1) | ZA200509780B (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060083795A1 (en) * | 2004-10-19 | 2006-04-20 | Lima Shatkina | Meal replacement products having appetite suppressing qualities |
| KR101307999B1 (ko) * | 2004-12-01 | 2013-09-12 | 니폰 조키 세야쿠 가부시키가이샤 | 건조물 및 그 제조방법 |
| US20060159773A1 (en) * | 2005-01-20 | 2006-07-20 | Stephen Holt | Herbal compositions containing hoodia |
| WO2007022141A1 (en) * | 2005-08-17 | 2007-02-22 | Charles Tadlock | Delivery system for appetite suppressant |
| CN101505771A (zh) * | 2006-08-17 | 2009-08-12 | 荷兰联合利华有限公司 | 含有甾体糖苷的hoodia植物萃取物的制造方法 |
| WO2008107910A2 (en) * | 2007-03-05 | 2008-09-12 | Ramaswamy Rajendran | Use of caralluma extracts in the inhibition of adipogenesis and a method of inhibition for the same |
| ZA201000727B (en) * | 2009-01-30 | 2010-11-24 | Vishwas Sudhu Ghare | An improved process for the preparation of caralluma extract and a formulation prepared thereof |
| US20130122146A1 (en) * | 2011-11-16 | 2013-05-16 | Decas Botanical Synergies, Llc | Process for Spray Drying Botanical Food |
| US9456916B2 (en) | 2013-03-12 | 2016-10-04 | Medibotics Llc | Device for selectively reducing absorption of unhealthy food |
| US9011365B2 (en) | 2013-03-12 | 2015-04-21 | Medibotics Llc | Adjustable gastrointestinal bifurcation (AGB) for reduced absorption of unhealthy food |
| US9067070B2 (en) | 2013-03-12 | 2015-06-30 | Medibotics Llc | Dysgeusia-inducing neurostimulation for modifying consumption of a selected nutrient type |
| TWI687223B (zh) | 2013-04-30 | 2020-03-11 | 日商日本臟器製藥股份有限公司 | 萃取物及含有該萃取物的製劑 |
| EP2810565A1 (en) * | 2013-06-03 | 2014-12-10 | Dupont Nutrition Biosciences ApS | Antioxidant composition |
| CN103969393A (zh) * | 2014-04-25 | 2014-08-06 | 上海相宜本草化妆品股份有限公司 | 用于化妆品中糖苷类中草药化合物含量测试的前处理方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3960839A (en) * | 1973-02-09 | 1976-06-01 | Escuela Politecnica Nacional | Process for recovering and isolating solasodine and glycosides thereof |
| US5270457A (en) * | 1992-06-12 | 1993-12-14 | University Of Manitoba | Cardiac steriod glycosides |
| ATE502041T1 (de) | 1997-04-15 | 2011-04-15 | Csir | Nicht-therapeutische methode zur appetitunterdrückung |
| EP0931550B1 (en) * | 1998-01-26 | 2004-09-22 | National Research Development Corporation, a Government of India Undertaking | A process for the preparation of a spermicidal agent |
| US6703051B1 (en) | 1998-10-13 | 2004-03-09 | Solae, Llc | Process for separating and recovering protein and isoflavones from a plant material |
| US6124442A (en) * | 1999-03-24 | 2000-09-26 | Zhou; James H. | Process for extracting triterpene glycosides from botanical sources |
| US6224906B1 (en) * | 1999-08-31 | 2001-05-01 | Natreon Inc. | St. John's wort composition |
| US6635758B2 (en) * | 2000-09-25 | 2003-10-21 | Industrial Technology Research Institute | Process for extracting glycoside using an aqueous two-phase system |
| EP1994837A3 (en) * | 2001-11-16 | 2009-11-11 | Nestec S.A. | Plant derived or derivable material with appetite suppressant activity |
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2004
- 2004-05-04 US US10/837,613 patent/US7060308B2/en not_active Expired - Lifetime
- 2004-05-31 AU AU2004244850A patent/AU2004244850B2/en not_active Expired
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- 2004-05-31 EP EP04735495A patent/EP1644013A1/en not_active Ceased
- 2004-05-31 CN CN200480015265.3A patent/CN1798566B/zh not_active Expired - Lifetime
- 2004-05-31 JP JP2006508488A patent/JP5260873B2/ja not_active Expired - Lifetime
- 2004-05-31 KR KR1020057023343A patent/KR20060034229A/ko not_active Ceased
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- 2004-05-31 KR KR1020077024499A patent/KR100993487B1/ko not_active Expired - Lifetime
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- 2004-05-31 BR BRPI0411400-0A patent/BRPI0411400A/pt not_active Application Discontinuation
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- 2005-12-01 ZA ZA200509780A patent/ZA200509780B/en unknown
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| Publication number | Publication date |
|---|---|
| US7060308B2 (en) | 2006-06-13 |
| CN1798566B (zh) | 2014-03-12 |
| AU2004244850A1 (en) | 2004-12-16 |
| NZ543995A (en) | 2009-02-28 |
| NZ573614A (en) | 2011-02-25 |
| KR20060034229A (ko) | 2006-04-21 |
| JP2013067638A (ja) | 2013-04-18 |
| JP2006526615A (ja) | 2006-11-24 |
| CA2527702C (en) | 2016-03-08 |
| AU2004244850B2 (en) | 2009-01-08 |
| WO2004108148A1 (en) | 2004-12-16 |
| KR20070114833A (ko) | 2007-12-04 |
| AU2008255233B2 (en) | 2012-01-12 |
| CA2527702A1 (en) | 2004-12-16 |
| US7390516B2 (en) | 2008-06-24 |
| US20040247702A1 (en) | 2004-12-09 |
| BRPI0411400A (pt) | 2006-07-25 |
| ZA200509780B (en) | 2006-09-27 |
| EP1644013A1 (en) | 2006-04-12 |
| KR100993487B1 (ko) | 2010-11-10 |
| CN1798566A (zh) | 2006-07-05 |
| US20050163871A1 (en) | 2005-07-28 |
| AU2008255233A1 (en) | 2009-01-22 |
| AU2004244850A2 (en) | 2004-12-16 |
| CO5660269A2 (es) | 2006-07-31 |
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