JP5208791B2 - Syringe assembly device - Google Patents

Description

  The present invention relates to a syringe assembly apparatus used for medical practice.

  In recent years, syringes for injecting medicinal solutions are often shipped in the form of prefilled syringes pre-filled with medicinal solutions. An example of the structure of a syringe composed of a barrel and a plunger is shown in FIGS.

  The barrel 101 is a cylindrical synthetic resin part, and a luer taper portion for attaching an injection needle is formed at one end. The luer taper portion is plugged with a sealing member 102 made of rubber or soft synthetic resin. A downward stepped portion in the middle of being narrowed down to the thickness of the luer tapered portion is a tapered portion 101a. A flange 103 is formed at the other end of the barrel 101. The flange 103 is for attaching a grip member (not shown) for hanging the index finger and the middle finger, and is not circular but has a shape having a major axis and a minor axis. FIG. 15A shows an example in which the flange 103 is a rounded rectangle, but other shapes such as an ellipse may be used.

  A gasket 104 made of rubber or soft synthetic resin is inserted into the barrel 101. On the end surface of the gasket 104 opposite to the end surface facing the luer taper portion, a threaded portion 105 is formed at a position overlapping the axial center of the barrel 101. The screw portion 105 is a right-handed female screw.

  A plunger rod 106 is combined with the gasket 104. The plunger rod 106 is a synthetic resin part having a cross-shaped cross section, and a knob 107 for receiving the belly of the thumb is formed at one end. The other end of the plunger rod 106 is formed with a threaded portion 108 that is screwed into the threaded portion 105 of the gasket 104 at the center of the axis. The screw part 108 is a right-handed male screw. By screwing and tightening the threaded portion 108 into the threaded portion 105 of the gasket 104 in the barrel 101, the gasket 104 and the plunger rod 106 are integrally connected to form a plunger 109 (see FIG. 16). 109 constitutes the syringe 100.

  After the syringe 100 is assembled, a label 110 is attached to the outer peripheral surface of the barrel 101 as shown in FIG. The label 110 displays information about the chemical solution that is the contents of the syringe 100 and a scale 111 of the chemical solution amount.

  An automated line is used to manufacture the syringe 100. Some automation lines include assembly equipment that performs the task of screwing the plunger rod into the gasket in the barrel. Examples of such assembling apparatuses can be seen in Patent Documents 1 and 2.

  In the syringe assembly device described in Patent Document 1, the plunger rod is screwed in by rotating the barrel while holding the plunger rod at a certain height so as not to rotate. The barrel is rotated by a belt mechanism provided obliquely on its side wall. In addition, labeling is performed while the barrel is conveyed by an array board (wheel).

  In the syringe assembly device described in Patent Document 2, the plunger rod is non-rotatably supported by a slider that moves up and down by the cam shape of the three-dimensional cam, and the plunger rod is screwed by rotating the barrel. The barrel is rotated by a belt.

JP 2002-95746 A JP 2004-195556 A

  A belt that frictionally contacts the barrel and transmits rotation also hinders free vertical movement of the barrel. In the case of the device described in Patent Document 1, it is necessary that the oblique arrangement angle of the belt and the lead angle of the screw be exactly the same. Otherwise, since the belt does not follow the rise of the barrel due to screwing, it may pass through the screwing station with insufficient rotation angle of screwing. In other words, every time the lead angle of the screw changes due to the difference in the type of syringe, the oblique arrangement angle of the belt must be adjusted.

  In the device described in Patent Document 2, it is necessary to lower the plunger rod in accordance with the rotation of the barrel. However, if there is a deviation in the position of the gasket, the screw portion of the gasket pulls down the plunger rod at the lead angle, and the three-dimensional cam As a result, wrinkles may occur during the lowering of the slider, and this may lead to passing through the screwing station with insufficient screw rotation angle.

  The present invention has been made in view of the above points, and an object of the present invention is to provide a syringe assembly apparatus that can reliably perform screwing to the end when a plunger rod is screwed into a gasket in a barrel.

In order to achieve the above object, the syringe assembly apparatus according to the present invention is configured such that when the plunger rod is screwed into the gasket in the barrel, the barrel is vertically oriented and the opening into which the plunger rod is inserted faces upward. A barrel support device that rotatably supports a predetermined height position, a chuck that sandwiches the plunger rod, and that is aligned on the opening of the barrel in a state where the axis is vertical, and is sandwiched by the chuck A plunger rod support device including a load applying device that applies a load to the plunger rod with its own mass; and a rotation applying device that rotates the barrel around an axis, and the tip is sandwiched between the chucks in the barrel. The load applying device applies a downward load in the axial direction to the plunger rod inserted into the Rolling imparting device, which gives a rotation direction in which the gasket and plunger rod of the screwing is performed in said barrel, said chuck, combined recesses were formed on the opposite surface to the cruciform cross-section of the plunger rod 1 A pair of fingers, wherein the pair of fingers firmly clamps the plunger rod from both sides to stop both rotation around the axis of the plunger rod and sliding in the axial direction; and The plunger rod support device can take a second clamping posture that stops a little while rotating the plunger rod around the axis but does not stop the sliding in the axial direction, and the plunger rod support device holds the plunger rod in the first clamping posture. First operation of lowering the sandwiched chuck and inserting the tip of the plunger rod into the barrel The chuck is placed in the second clamping position to perform a second operation in which the load applying device applies a downward load in the axial direction to the plunger rod, and the rotation applying device is configured such that the plunger rod supporting device is the second operation. When performing the above, the barrel is rotated .

According to this configuration, the load applying device that applies a load with the mass of the load applying device itself applies a downward load in the axial direction to the plunger rod, and rotates the barrel with the rotation applying device to screw the gasket and the plunger rod. As the screwing progresses, the plunger rod naturally lowers, and there is no wrinkle between the movement of the gasket thread pulling down the plunger rod at the lead angle and the actual movement of the plunger rod, ensuring the screwing to the end. Can be carried out.

In addition , when the chuck is in the second pinching position in which the plunger rod stops rotating around the axis of the plunger rod but does not stop the plunger rod in the axial direction, the load is applied while applying a downward load in the axial direction to the plunger rod. Since the barrel is rotated by the device to screw the gasket and the plunger rod, the screwing proceeds without hindering the lowering of the plunger rod.

  In the syringe assembly device, the barrel support device and the plunger rod support device may be arranged at equiangular intervals on a peripheral edge of a turret that rotates about a vertical axis. A solid cam arranged along a circular trajectory of a rod support device; and a chuck support shaft supported by the turret so as to be vertically movable and vertically moved along a cam shape of the solid cam. The turret, the rotary shuttle, and the rotation imparting device are driven by independent motors, respectively.

  According to this configuration, when parameters such as the barrel rotation angle and barrel outer diameter necessary to complete the screwing change, it can be easily dealt with by changing the motor control program of the rotation imparting device, Convenience is good.

  According to the present invention, even if there is an error in the gasket position in the barrel, it is possible to achieve the desired screwing of the gasket and the plunger rod.

It is a top view which shows typically schematic structure of the syringe assembly apparatus which concerns on this invention. It is a vertical sectional view of the barrel support device and the plunger rod support device. It is a top view of the chuck | zipper of a fully open posture. It is a top view of the chuck | zipper of the 1st clamping condition. It is a top view of the chuck | zipper of the 2nd clamping condition. It is a horizontal sectional view which shows schematic structure of a rotation provision apparatus. It is the 1st explanatory view of a syringe assembly process. It is the 2nd explanatory view of a syringe assembly process. It is the 3rd explanatory view of a syringe assembly process. It is a vertical sectional view explaining the composition of the conveyor which carries the assembled syringe to the label sticking step. It is sectional drawing of the bucket which comprises the conveyor of FIG. It is explanatory drawing which shows a label sticking process in the form of a top view. It is explanatory drawing which shows a label sticking process in the form of a front view. It is a figure which shows the structural example of a syringe, (a) is a vertical sectional view of a barrel, (b) is a side view of a plunger rod. It is a figure which shows the structural example of a syringe, (a) is an end elevation of a barrel, (b) is an end elevation of a plunger rod. It is a vertical sectional view of the syringe in an assembled state. It is a side view of the syringe which stuck the label.

  Embodiments of the present invention will be described below with reference to the drawings. A syringe assembly apparatus 1 schematically shown in FIG. 1 includes three turrets generally called star wheels. All of the three turrets are configured as rotating bodies that rotate around the vertical axis, and are set so that their peripheral speeds are equal to each other. Of the three turrets, the first one is the component receiving turret 10, the second is the syringe assembly turret 20, and the third is the relay turret 40. The syringe assembly turret 20 is combined with a rotary shuttle 50 that reciprocates on an arc track having the same center.

  The parts receiving turret 10 receives the plunger rod 106 shown in FIGS. 14 to 16 from the linear feeder 11 and the barrel 101 from the linear feeder 12 and supplies them to the syringe assembly turret 20 in the form of aligning them on the vertical axis. To do. While the syringe assembly turret 20 carries the barrel 101 and the plunger rod 106 to the relay turret 40, the rotation imparting device 60 mounted on the rotary shuttle 50 running along with the syringe assembly turret 20 gives rotation to the barrel 101, and The syringe rod 100 is assembled by screwing the plunger rod 106. This mechanism will be described in detail later. The assembled syringe 100 is delivered from the syringe assembly turret 20 to the relay turret 40, and further delivered from the relay turret 40 to the conveyor 70 of the labeling line.

  The component receiving turret 10 is driven by a motor 13, the syringe assembly turret 20 is driven by a motor 21, the rotary shuttle 50 is driven by a motor 51, the rotation applying device 60 is driven by a motor 61, and the relay turret 40 is driven by a motor 41. The sprocket 71 driven and provided at one end of the conveyor 70 is driven by a motor 72. The motors 51 and 61 are servo motors. The motors 13, 21, 41, 72 may be ordinary induction motors. Replace all or some combinations of motors 13, 21, 41, 72 with a single motor, and distribute the rotation of the single motor to the turret or conveyor by means of power transmission means such as a gear train or timing belt. May be.

  The motor 13 rotates the component receiving turret 10, the motor 21 rotates the syringe assembly turret 20, the motor 41 rotates the relay turret 40, and the motor 72 rotates the sprocket 71 continuously. The motor 51 reciprocates the rotary shuttle 50 along the circular arc track. As an example of a mechanism in which the motor 51 applies the reciprocating power to the rotary shuttle 50, a configuration in which an arc-shaped rack is fixed to the rotary shuttle 50 and a pinion engaged with the rack is driven by the motor 51 can be cited as an example. It is not limited to this.

  On the periphery of the syringe assembly turret 20, a total of 18 barrel support devices 22 shown in FIG. The barrel support device 22 can rotate around the axis at a predetermined height position with one barrel 101 set to a vertical position and the opening into which the plunger rod 106 is inserted is directed upward. To support.

  The barrel support device 22 includes a backup roller 23 that supports the side surface of the barrel 101. The backup roller 23 is supported so as to be able to rotate around the vertical axis, and forms a set of two as shown in FIG. When the flange 24 formed at the lower end of the backup roller 23 receives the tapered portion 101a of the barrel 101, the barrel 101 is held at the height.

  In the barrel 101, if the stepped portion transitioning to the thickness of the luer taper portion forms a surface perpendicular to the barrel axis direction, it can be said that the height of the barrel 101 is constant when it is received by the flange 24. However, when the tapered portion 101a is formed as in the embodiment, it is not determined which portion of the tapered surface the flange portion 24 hits. That is, the height of the barrel 101 must be varied. Therefore, if the label 110 is applied while the syringe assembly turret 20 conveys the barrel 101 according to Patent Document 1, it is inevitable that the application position of the label 110 varies. In view of this, the syringe assembly turret 20 is not provided with a label attaching means, and the label attaching means is disposed at a location described later.

  An arcuate fixed guide 25 is provided outside the syringe assembly turret 20, and this fixed guide 25 prevents the barrel 101 from falling off the backup roller 23. A clearance of about 0.5 mm is provided between the fixed guide 25 and the barrel 101.

  In the syringe assembly turret 20, a plunger rod support device 26 is arranged in a pair with the barrel support device 22. The plunger rod support device 26 includes two chuck support shafts 27a and 27b penetrating the syringe assembly turret 20 vertically and slidably up and down, a deck 28 supported by upper ends of the chuck support shafts 27a and 27b, and a deck. A chuck 29 supported by 28 is provided. The chuck 29 holds the plunger rod 106 in a state where the plunger rod 106 is perpendicular to the axis, and aligns the plunger rod 106 on the opening of the barrel 101 supported by the barrel support device 22.

  As shown in FIGS. 3 to 5, the chuck 29 includes a pair of fingers 30 a and 30 b, and the fingers 30 a and 30 b are closed to sandwich the plunger rod 106 from both sides. On the opposing surfaces of the fingers 30a and 30b, a recess is formed in accordance with the cross section of the plunger rod 106. When the cross section enters the recess as shown in FIG. Rotation is stopped.

  The chuck 29 takes three opening angles by a power source (not shown). The first is the fully open state shown in FIG. 3. At this time, the fingers 30 a and 30 b are separated from the plunger rod 106, and the plunger rod 106 can freely rotate and move in the axial direction with respect to the chuck 29. it can. The second is a first clamping posture shown in FIG. 4, and the fingers 30a and 30b firmly clamp the plunger rod 106 from both sides. At this time, the plunger rod 106 cannot stop rotating around the axis, and cannot slide in the axial direction with respect to the chuck 29. The third clamping posture shown in FIG. 5 is that the fingers 30a and 30b are slightly opened from the first clamping posture, and the plunger rod 106 still cannot rotate around the axis, but slides in the axial direction with respect to the chuck 29. It becomes possible.

  The plunger rod support device 26 is moved up and down by a three-dimensional cam 31 arranged along its orbit. The three-dimensional cam 31 is an annular member arranged coaxially with a rotation shaft (not shown) of the syringe assembly turret 20 and is attached to a table (not shown) that supports the syringe assembly turret 20. A cam groove 32 is formed on the outer peripheral surface of the three-dimensional cam 31, and a cam follower roller 33 attached to the lower end of the chuck support shaft 27a is engaged with the cam groove 32. A vertical movement according to the cam shape of the cam groove 32 is given to the chuck support shaft 27a. The three-dimensional cam 31 and the support shaft 27a constitute a chuck raising / lowering device 34.

  The plunger rod support device 26 includes a load applying device 35. The load applying device 35 includes a pressing shaft 36 that penetrates the deck 29 of the plunger rod support device 26 vertically and slidably, a disk-shaped pressing head 37 fixed to the lower end of the pressing shaft 36, and a pressing shaft. The cam follower roller 38 attached to the upper end of 36 is provided. A solid cam 39 (see FIG. 7) on which the cam follower roller 38 rides is provided on a part of the circular path of the load applying device 35, and the pressing shaft 36 has a cam surface (the upper surface of the solid cam 39). A vertical movement according to the undulations is given.

  The rotation imparting device 60 mounted on the rotary shuttle 50 includes three combinations of a motor 61 and a roller 62 rotated by the motor 61. The angular interval between the rollers 62 is equal to the angular interval between the barrel support devices 22. The roller 62 comes into contact with the outer peripheral surface of the barrel 101 supported by the barrel support device 22 and gives rotation to the barrel 101.

  The syringe assembly operation proceeds as follows. A pair of barrel support device 22 and plunger rod support device 26 arranged on the periphery of the syringe assembly turret 20 sequentially pass through a total of 18 angular positions (A0 to A17) set at equiangular intervals. The angle position A0 is a contact point between the syringe assembly turret 20 and the component receiving turret 10, and a contact point between the syringe assembly turret 20 and the relay turret 40 is between the angle position A15 and the angle position A16. The fixed guide 25 is arranged so as to cover a section extending from the angular position A0 to the angular position A15.

  As shown in FIG. 7, the chuck 29 of the plunger rod support device 26 is lifted high by the cam groove 32 at the angular position A0. The load applying device 35 that causes the cam follower roller 38 to ride on the three-dimensional cam 39 before the angular position A16 is also lifted high by the three-dimensional cam 39 at the angular position A0. In this position, the barrel support device 22 is handed over the barrel 101 from the component receiving turret 10 and the plunger rod support device 26 is handed over the plunger rod 106 from the component receiving turret 10. The chuck 29 is initially in the fully open state shown in FIG. 3, but as soon as the plunger rod 106 is inserted, it takes the first holding state shown in FIG. 4 and firmly holds the plunger rod 106.

  The chuck 29 sandwiching the plunger rod 106 in the first clamping posture is lowered in height as it moves from the angular position A0 → A1 → A2 → A3, and the plunger rod 106 has its tip (lower end) in the barrel 101 in the process. Inserted. This is the first operation of the plunger support device 26. At the angular position A2, the chuck 29 changes its posture from the first clamping posture to the second clamping posture. As a result, the plunger rod 106 cannot rotate around the axis, but can slide down from the chuck 29. Even if it becomes possible to slide down from the chuck 29, in many cases, the plunger rod 106 does not fall down to the point where the screw part 108 contacts the screw part 105 of the gasket 104, but the height to that point is reached. Stay on.

  Here, the load applying device 35 whose height has been lowered in accordance with the chuck 29 is detached from the solid cam 39 between the angular positions A2 and A3, and applies a downward load in the axial direction due to its own mass to the plunger rod 106. As a result, the plunger rod 106 is forcibly pushed down until the screw portion 108 contacts the screw portion 105. This is the second operation of the plunger support device 26. After the second operation, a gap h <b> 1 is generated between the lower surface of the knob 107 of the plunger rod 106 and the upper surface of the chuck 29.

  The barrel support device 22 remains at the original height, and the chuck 29 moves to the angular position A9 at the angular position A3 while maintaining the height given by the chuck lifting / lowering device 34. The rotation applying device 60 advances the rollers 62 toward the three barrels 101 existing at the angular positions A3, A4, and A5, respectively, and elastically presses the rollers 62 against the barrel 101 by a spring (not shown). In this state, the rotation applying device 60 drives the roller 62 by the motor 61 and rotates the barrel 101 while running alongside the syringe assembly turret 20. The rotation direction is a direction in which the screw portion 105 of the gasket 104 is screwed into the screw portion 108 of the plunger rod 106.

  As the screwing proceeds, the plunger rod 106 whose rotation about the axis is stopped by the chuck 29 is lowered. The situation is shown in FIG. In each of the three barrels 101, when the screw part 105 is screwed into the screw part 108 to the end, the screwing torque reaches the set torque value. The motors 61 that have reached the set torque value individually stop rotating. The torque when the motor 61 stops rotating, that is, the set torque value, is set to the maximum value in a range in which relative rotation is not caused between the barrel 101 and the gasket 104. For this reason, the gasket 104 is forcibly rotated and the outer peripheral surface is not worn due to friction with the inner surface of the barrel 101.

  In this way, the gasket 104 and the plunger rod 106 are screwed by rotating the barrel 101 with the rotation applying device 60 while applying a downward load in the axial direction to the plunger rod 106 with the load applying device 35 that applies the load with its own mass. Therefore, the plunger rod 106 naturally descends as the screwing progresses, and there is no wrinkle between the movement of the screw portion 105 of the gasket 104 pulling down the plunger rod 106 at the lead angle and the actual movement of the plunger rod 106. The screwing can be surely performed to the end.

  Further, when the chuck 29 is in the second clamping posture in which the plunger 29 stops rotating around the axis of the plunger rod 106 but does not stop the plunger rod 106 in the axial direction, the load applying device 35 causes the plunger rod 106 to face downward in the axial direction. Since the gasket 101 and the plunger rod 106 are screwed by rotating the barrel 101 with the rotation applying device 60 while applying a load, the screwing proceeds without hindering the lowering of the plunger rod 106.

  When the screw part 105 is screwed into the screw part 108 to the end, the barrel 101, the gasket 104, and the plunger rod 106 become the assembled syringe 100. Although the distance between the lower surface of the knob 107 and the upper surface of the chuck 29 is reduced to h2 (see FIG. 8), the knob 107 still does not contact the chuck 29. The gap h2 is a space, and variations in the insertion depth of the gasket 104 with respect to the barrel 101 can be absorbed.

  The rotary shuttle 50 reverses its movement immediately before the three barrels 101 that were originally positioned at the angular positions A3, A4, and A5 advance the angular position by three sections and reach A6, A7, and A8. It returns to the position where the barrel 101 arriving at the angular positions A3, A4, A5 is greeted. At this time, the roller 62 is pulled back to the retracted position against the force of the spring, and does not contact the barrel 101 and rotate it during the return.

  When parameters such as the rotation angle of the barrel 101 and the outer diameter of the barrel 101 that are necessary to complete the screwing change, it can be easily dealt with by changing the control program of the motor 61 of the rotation applying device 60.

  As shown in FIG. 9, when the chuck 29 reaches the angular position A10, the chuck 29 is fully opened. As the angular position moves from A10 → A11 → A12 → A13, the chuck 29 is lifted away from the syringe 100. When the chuck 29 is fully opened, the knob 107 of the plunger rod 106 is allowed to pass but the pressing head 37 is not allowed to pass, and the load applying device 35 is lifted by the chuck 29. The chuck 29 reaches the maximum height at the angular position A13, proceeds from the angular position A14 to A15 without changing the height, and causes the cam follower roller 38 to ride on the solid cam 39 at the angular position A16.

  The syringe 100 changes to the relay turret 40 after passing the angular position A15. The fixed guide similar to the fixed guide 25 prevents the syringe 100 from dropping from the relay turret 40. The relay turret 40 delivers the syringe 100 to the conveyor 70 at a point about a half turn from the syringe receiving point.

  The conveyor 70 is formed by connecting a plurality of buckets 73 shown in FIGS. 10 and 11 at regular intervals. Similar to the barrel support device 22, the bucket 73 includes two backup rollers 74 and rotatably supports the syringe 100.

  The axis of the sprocket 71 of the conveyor 70 is inclined by 45 °, and the bucket 73 has the axis of the backup roller 74 vertical as shown on the left side of FIG. 10 when receiving the syringe 100 from the relay turret 40. The posture changes as it goes around 71, and when it leaves the sprocket 71, the axis of the backup roller 74 becomes horizontal as shown on the right side of FIG. That is, the bucket 73 receives the syringe 100 in a vertical state, changes the posture thereof to a horizontal state, and carries the syringe 100 to a label attaching work unit described later. Until the syringe 100 becomes horizontal, the syringe 100 may drop from the bucket 73. Therefore, a fixed guide 75 similar to the fixed guide 25 of the syringe assembly turret 20 is provided around the sprocket 71 so that the syringe 100 is horizontal. Keep the syringe 100 from dropping from the bucket 73 until it is close to it.

  As shown in FIG. 13, a recess 76 that receives the flange 103 of the barrel 101 is formed on one side surface of the bucket 73. The hollow 76 is designed to receive the flange 103 of the syringe 100 in a horizontal state in a state where the long axis of the flange 103 is horizontal. Is prevented from rotating, that is, transported in such a way that the angle does not change. This is to make the label attachment position (angle) in the syringe 100 constant. At the time of receiving the syringe 100 from the relay turret 40, the bucket 73 has the side surface on the side where the recess 76 is provided facing upward, and the syringe 100 changes from the vertical state to the horizontal state with the flange 103 settled in the recess 76. And change posture.

  The bucket 73 that has left the sprocket 71 travels horizontally in a section of the conveyor 70 that includes the label pasting unit 77 shown in FIGS. 12 and 13. In this partial section, the bucket 73 can rotate the syringe 100 with the plunger rod 106 screwed into the gasket 104 in the barrel 101 around the axis line so that the axis line is horizontal and perpendicular to the traveling direction of the conveyor 70. To support. However, the rotation around the axis of the syringe 100 is stopped while the flange 103 is in the recess 76.

  Work positions S1 to S4 are set in the label attaching work section 77, and a fixed guide plate 78 that covers a section of the work positions S1 to S4 is arranged side by side with the bucket 73. The fixed guide plate 78 and the conveyor 70, and a label sticking means 81 to be described later constitute a label sticking device 83 to the syringe 100.

  The fixed guide plate 78 is located beside the bucket 73 on the side where the recess 76 exists. The fixed guide plate 78 is horizontally arranged such that the longitudinal direction is parallel to the traveling path of the bucket 73.

  The syringe 100 placed on the bucket 73 and arriving at the label attaching work unit 77 is changed in position with respect to the bucket 73 before the work position S1. That is, a guide surface 79 is formed at the distal end of the fixed guide plate 78 so as to cross obliquely with respect to the traveling direction of the syringe 100, and the knob 107 of the plunger rod 106 is engaged with this. When the bucket 73 advances to the left in FIG. 12, the syringe 100 is moved in the axial direction (downward in FIG. 12), and the flange 103 is pulled out from the recess 76. This means that the syringe 100 can be rotated with respect to the bucket 73.

  On the way from the work position S1 to the work position S2, the flange 103 is guided into the guide groove 80 formed in the fixed guide plate 78. The guide groove 80 extends in parallel with the traveling direction of the bucket 73, and the inlet portion widens in a tapered shape to receive the flange 103. The width of the guide groove 80 becomes narrower as it goes deeper, and narrows to a degree slightly wider than the width of the flange 103 around the work position S3. As a result, the syringe 100 is restricted in position in the axial direction by the flange 103 being sandwiched between the opposed inner walls of the guide groove 80 after the operation position S3.

  Since the flange 103 of the syringe 100 is guided into the guide groove 80 of the fixed guide plate 78 fixed to an immovable member such as an apparatus base, the position of the syringe 100 is less likely to fluctuate due to vibration accompanying conveyance, and the positioning accuracy of the label 110 is increased. Can be increased.

  As shown in FIG. 13, the depth of the guide groove 80 is not uniform, and is a shallow groove portion 80a around the work position S2. The depth of the shallow groove portion 80a is a depth indicating whether or not the flange 103 whose horizontal axis is horizontal touches the bottom. For this reason, the syringe 100 passes the work position S2 while keeping the long axis of the flange 100 horizontal.

  Until the flange 103 enters the guide groove 80 and the shallow groove portion is ready to advance while maintaining the long axis of the flange horizontally, the rotation of the syringe 100 around the axis line can be stopped by the recess 76 of the bucket 73. The syringe 100 does not rotate due to the vibration when moving, and the flange 103 can be fed into the guide groove 80 at a constant angle.

  The guide groove 80 becomes deeper from the front of the work position S3 and becomes a deep groove portion 80b at the work position S3. The depth of the deep groove portion 80b is such a depth that the flange 103 does not touch the bottom even when the flange 103 rotates around the barrel axis.

  The label sticking means 81 starts sticking the label 110 from the work position S3. The label affixing means 81 has a label adsorbing belt 82 that runs parallel to the conveyor 70 as a main component, and adsorbs the label 110 on the label adsorbing belt 82 with the adhesive surface facing outward. One end of the label 110 contacts the outer peripheral surface of the barrel 101 at the work position S3. Until then, the long axis of the flange 103 has been maintained horizontally by the shallow groove portion 80a of the guide groove 80, so that the label 110 starts to be applied from a fixed position on the outer periphery of the barrel 101. Thereby, the label 110 can be affixed stably at an angle that is easy for the user to see.

  The syringe 100 rolls the label 110 while rolling on the bucket 73. In the figure, the setting is such that the winding of the label 110 is completed at the work position S4. At that time, the flange 103 is in a state where the major axis is vertical. This setting is an example, and the present invention is not limited to this.

  Since the bucket 73 supports the syringe 100 with the two backup rollers 74, the syringe 100 can be rotated around the axis with little resistance, and the label 110 can be wound neatly.

  Since the flange 110 is guided into the narrow guide groove 80 and the label 110 is pasted, the label 110 is pasted with the barrel 101 positioned in the axial direction. As a result, the sticking position of the label 110 to the barrel 101 is accurate both in the angle and in the axial direction. Since the label 110 is often formed with a scale for the amount of the chemical solution, if the sticking position in the axial direction of the barrel 101 is accurate, the amount of the chemical solution can be known more accurately, which is useful for appropriate administration. .

  The main components of the label sticking means 81 are not limited to the label suction belt 82. It may be a drum. In short, it is only necessary that the application of the label 110 can be started from a certain position on the outer periphery of the barrel 101 at the work position S3.

  Although the embodiments of the present invention have been described above, the scope of the present invention is not limited to these embodiments, and various modifications can be made without departing from the spirit of the invention. Moreover, the quantity and numerical value which appear in this specification are an example to the last, and do not limit invention.

  The present invention is applicable to a prefilled syringe assembly apparatus.

DESCRIPTION OF SYMBOLS 1 Syringe assembly apparatus 20 Syringe assembly turret 21 Motor 22 Barrel support apparatus 26 Plunger rod support apparatus 27a, 27b Chuck support shaft 29 Chuck 31 Three-dimensional cam 34 Chuck up-and-down apparatus 35 Load application apparatus 50 Rotary shuttle 51 Motor 60 Rotation application apparatus 61 Motor 100 Syringe 101 Barrel 103 Flange 104 Gasket 105 Threaded portion 106 Plunger rod 107 Knob 108 Threaded portion

Claims (2)

In the syringe assembly device that screws the plunger rod into the gasket in the barrel,
A barrel support device that rotatably supports the barrel at a predetermined height position in a state where the axis is vertical and the opening into which the plunger rod is inserted faces upward;
A chuck that aligns on the opening of the barrel with the plunger rod sandwiched and the axis is vertical, and a load that applies a load to the plunger rod sandwiched between the chucks by the mass of the load applying device itself A plunger rod support device comprising an applicator device;
A rotation imparting device for rotating the barrel around an axis;
The load applying device applies a downward load in the axial direction to the plunger rod sandwiched between the chucks and having the tip inserted into the barrel. In this state, the rotation applying device is connected to the gasket and the plunger rod. Giving the barrel a rotation in the direction in which it is screwed ;
The chuck includes a pair of fingers formed on opposite surfaces with depressions matched to the cross-shaped cross section of the plunger rod, and the pair of fingers firmly holds the plunger rod from both sides around the axis of the plunger rod. A first clamping posture to stop both rotation and axial slip, and a second clamping posture in which the pair of fingers are slightly opened and rotation around the axis of the plunger rod is stopped but sliding in the axial direction is not stopped. Is what you get
The plunger rod supporting device lowers the chuck that sandwiches the plunger rod in the first clamping posture and inserts the tip of the plunger rod into the barrel, and the chucking posture in the second clamping posture. And performing the second operation of applying a downward load in the axial direction to the plunger rod with the load applying device,
The syringe assembly device according to claim 1, wherein the rotation imparting device imparts rotation to the barrel when the plunger rod support device performs the second operation . The barrel support device and the plunger rod support device are arranged at equiangular intervals on the periphery of the turret that rotates about a vertical axis.
The chuck lifting and lowering device includes a three-dimensional cam arranged along a circular locus of the plunger rod support device, and a chuck support shaft that is supported by the turret so as to be vertically movable and moves up and down along the cam shape of the three-dimensional cam.
The rotation imparting device is supported by a rotary shuttle that reciprocates on an arc orbit having the same center as the turret,
The syringe assembly apparatus according to claim 1, wherein the turret, the rotary shuttle, and the rotation imparting device are driven by independent motors .

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