JP5202334B2 - ソフトセグメントと均一長さのハードセグメントの両者を有する共重合体含有ポリマー領域を持つ治療薬送達用医療器具 - Google Patents

ソフトセグメントと均一長さのハードセグメントの両者を有する共重合体含有ポリマー領域を持つ治療薬送達用医療器具 Download PDF

Info

Publication number
JP5202334B2
JP5202334B2 JP2008553251A JP2008553251A JP5202334B2 JP 5202334 B2 JP5202334 B2 JP 5202334B2 JP 2008553251 A JP2008553251 A JP 2008553251A JP 2008553251 A JP2008553251 A JP 2008553251A JP 5202334 B2 JP5202334 B2 JP 5202334B2
Authority
JP
Japan
Prior art keywords
segment
medical device
uniform
polymer
polyether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2008553251A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009525125A5 (enExample
JP2009525125A (ja
Inventor
ロバート ワーナー,
マイケル, エス. アーニー,
リリアーナ アタナソスカ,
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Ltd Barbados
Original Assignee
Boston Scientific Ltd Barbados
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Scientific Ltd Barbados filed Critical Boston Scientific Ltd Barbados
Publication of JP2009525125A publication Critical patent/JP2009525125A/ja
Publication of JP2009525125A5 publication Critical patent/JP2009525125A5/ja
Application granted granted Critical
Publication of JP5202334B2 publication Critical patent/JP5202334B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow
    • A61L2300/604Biodegradation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
JP2008553251A 2006-01-31 2007-01-18 ソフトセグメントと均一長さのハードセグメントの両者を有する共重合体含有ポリマー領域を持つ治療薬送達用医療器具 Expired - Fee Related JP5202334B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/344,053 2006-01-31
US11/344,053 US8440214B2 (en) 2006-01-31 2006-01-31 Medical devices for therapeutic agent delivery with polymeric regions that contain copolymers having both soft segments and uniform length hard segments
PCT/US2007/001296 WO2007089435A2 (en) 2006-01-31 2007-01-18 Medical devices for therapeutic agent delivery

Publications (3)

Publication Number Publication Date
JP2009525125A JP2009525125A (ja) 2009-07-09
JP2009525125A5 JP2009525125A5 (enExample) 2010-03-04
JP5202334B2 true JP5202334B2 (ja) 2013-06-05

Family

ID=38229939

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008553251A Expired - Fee Related JP5202334B2 (ja) 2006-01-31 2007-01-18 ソフトセグメントと均一長さのハードセグメントの両者を有する共重合体含有ポリマー領域を持つ治療薬送達用医療器具

Country Status (5)

Country Link
US (2) US8440214B2 (enExample)
EP (1) EP1979014B1 (enExample)
JP (1) JP5202334B2 (enExample)
CA (1) CA2641457A1 (enExample)
WO (1) WO2007089435A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9028859B2 (en) * 2006-07-07 2015-05-12 Advanced Cardiovascular Systems, Inc. Phase-separated block copolymer coatings for implantable medical devices
JP2010512947A (ja) 2006-12-20 2010-04-30 ボストン サイエンティフィック リミテッド 治療薬を送達するためのコーティングを備えたステント
KR20120106880A (ko) 2007-01-21 2012-09-26 헤모텍 아게 체강의 협착 치료 및 급성 재협착 예방을 위한 의료 제품
US8202528B2 (en) * 2007-06-05 2012-06-19 Abbott Cardiovascular Systems Inc. Implantable medical devices with elastomeric block copolymer coatings
US8293260B2 (en) * 2007-06-05 2012-10-23 Abbott Cardiovascular Systems Inc. Elastomeric copolymer coatings containing poly (tetramethyl carbonate) for implantable medical devices
US20080306582A1 (en) * 2007-06-05 2008-12-11 Yunbing Wang Implantable medical devices with elastomeric copolymer coatings
US20090004243A1 (en) 2007-06-29 2009-01-01 Pacetti Stephen D Biodegradable triblock copolymers for implantable devices
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
EP2214736B1 (en) * 2007-10-29 2014-03-05 Zimmer, Inc. Medical implants and methods for delivering biologically active agents
CA2720864C (en) * 2008-04-07 2017-07-04 National Institute Of Immunology Compositions useful for the treatment of diabetes and other chronic disorder
US20090306769A1 (en) * 2008-06-06 2009-12-10 Boston Scientific Scimed, Inc. Medical balloon made with hybrid polymer-ceramic material and method of making and using the same
US8389083B2 (en) * 2008-10-17 2013-03-05 Boston Scientific Scimed, Inc. Polymer coatings with catalyst for medical devices
US20100131001A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Targeted Drug Delivery for Aneurysm Treatment
IT1394522B1 (it) 2009-01-09 2012-07-05 Invatec Technology Ct Gmbh Dispositivo medicale con rilascio di farmaco
WO2010124098A2 (en) * 2009-04-24 2010-10-28 Boston Scientific Scimed, Inc. Use of drug polymorphs to achieve controlled drug delivery from a coated medical device
EP2451496B1 (en) 2009-07-10 2015-07-22 Boston Scientific Scimed, Inc. Use of nanocrystals for a drug delivery balloon
WO2011008393A2 (en) * 2009-07-17 2011-01-20 Boston Scientific Scimed, Inc. Nucleation of drug delivery balloons to provide improved crystal size and density
WO2012031236A1 (en) 2010-09-02 2012-03-08 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
US8669360B2 (en) 2011-08-05 2014-03-11 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
US9056152B2 (en) 2011-08-25 2015-06-16 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
JP6307492B2 (ja) * 2013-04-01 2018-04-04 テルモ株式会社 薬剤投与バルーンカテーテル及びその製造方法
JP6315298B2 (ja) * 2013-08-30 2018-04-25 エルジー・ケム・リミテッド ブロック共重合体
WO2015030550A1 (ko) * 2013-08-30 2015-03-05 주식회사 엘지화학 블록 공중합체
CN116813803B (zh) * 2023-08-25 2023-11-28 北京科技大学 用于高效装载雷帕霉素的多肽纳米材料及制备方法和应用

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5614549A (en) 1992-08-21 1997-03-25 Enzon, Inc. High molecular weight polymer-based prodrugs
US6406457B1 (en) 1994-03-02 2002-06-18 Scimed Life Systems, Inc. Block copolymer elastomer catheter balloons
US6441025B2 (en) 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
AUPO251096A0 (en) * 1996-09-23 1996-10-17 Cardiac Crc Nominees Pty Limited Polysiloxane-containing polyurethane elastomeric compositions
EP1011744A2 (en) * 1997-09-17 2000-06-28 Advanced Cardiovascular Systems, Inc. Polyether block amide catheter balloons
TR200002450T2 (tr) * 1998-02-23 2001-01-22 Massachusetts Institute Of Technology Şekil belleği olan biyobozunur polimerler.
US6299980B1 (en) * 1998-09-29 2001-10-09 Medtronic Ave, Inc. One step lubricious coating
US6315790B1 (en) * 1999-06-07 2001-11-13 Scimed Life Systems, Inc. Radiopaque marker bands
US6620127B2 (en) * 1999-12-01 2003-09-16 Advanced Cardiovascular Systems, Inc. Medical device balloon
US6716444B1 (en) * 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
CA2438193A1 (en) 2001-02-26 2002-09-06 Duke University Novel dendritic polymers and their biomedical uses
US20020188314A1 (en) * 2001-06-07 2002-12-12 Microvena Corporation Radiopaque distal embolic protection device
US6585755B2 (en) * 2001-06-29 2003-07-01 Advanced Cardiovascular Polymeric stent suitable for imaging by MRI and fluoroscopy
US6765069B2 (en) * 2001-09-28 2004-07-20 Biosurface Engineering Technologies, Inc. Plasma cross-linked hydrophilic coating
US8133501B2 (en) 2002-02-08 2012-03-13 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled drug delivery
US20050234215A1 (en) * 2002-02-21 2005-10-20 Gaymans Reinoud J Segmented copoymer containing amide segments
US6835387B2 (en) * 2002-06-11 2004-12-28 Scimed Life Systems, Inc. Sustained release of superoxide dismutase mimics from implantable or insertable medical devices
US8211455B2 (en) 2002-06-19 2012-07-03 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled delivery of a therapeutic agent
WO2004005533A2 (en) * 2002-07-10 2004-01-15 University Of Florida Sol-gel derived bioactive glass polymer composite
AU2003258206A1 (en) 2002-08-13 2004-02-25 Medtronic, Inc. Active agent delivery system including a polyurethane, medical device, and method
US7491234B2 (en) * 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
DE10355318A1 (de) * 2003-11-27 2005-06-23 Wacker-Chemie Gmbh Verfahren zur Herstellung von organyloxysilylterminierten Polymeren
DE102004008202A1 (de) * 2004-02-18 2005-09-01 Basf Ag Komposites aus Thermoplasten mit monodispers verteilten Füllstoffen
JP4768736B2 (ja) * 2004-08-13 2011-09-07 レヴァ メディカル、 インコーポレイテッド 多重使用のための本質的に放射線不透過性の生体吸収性ポリマー
US7862835B2 (en) 2004-10-27 2011-01-04 Boston Scientific Scimed, Inc. Method of manufacturing a medical device having a porous coating thereon
US9125968B2 (en) 2005-03-30 2015-09-08 Boston Scientific Scimed, Inc. Polymeric/ceramic composite materials for use in medical devices
US7291166B2 (en) * 2005-05-18 2007-11-06 Advanced Cardiovascular Systems, Inc. Polymeric stent patterns

Also Published As

Publication number Publication date
CA2641457A1 (en) 2007-08-09
US8440214B2 (en) 2013-05-14
EP1979014A2 (en) 2008-10-15
EP1979014B1 (en) 2013-07-03
US20070178136A1 (en) 2007-08-02
WO2007089435A3 (en) 2008-08-21
WO2007089435A2 (en) 2007-08-09
US20130251778A1 (en) 2013-09-26
JP2009525125A (ja) 2009-07-09

Similar Documents

Publication Publication Date Title
JP5202334B2 (ja) ソフトセグメントと均一長さのハードセグメントの両者を有する共重合体含有ポリマー領域を持つ治療薬送達用医療器具
US9468707B2 (en) Biodegradable triblock copolymers for implantable devices
US9028859B2 (en) Phase-separated block copolymer coatings for implantable medical devices
US9125968B2 (en) Polymeric/ceramic composite materials for use in medical devices
EP1663331B1 (en) Implantable or insertable medical devices containing silicone copolymer for controlled delivery of therapeutic agents
US8952123B1 (en) Dioxanone-based copolymers for implantable devices
US20070207182A1 (en) Medical devices having electrically aligned elongated particles
US20060115449A1 (en) Bioabsorbable, biobeneficial, tyrosine-based polymers for use in drug eluting stent coatings
JP6080172B2 (ja) コーティング用置換ポリカプロラクトン
JP2009530040A (ja) ポリマーブラシを有する医療器具
JP2008528212A (ja) 制御された薬物送達および調節された生体適合性のための多孔質高分子領域を有する医療機器
JP2008526322A (ja) 多層を含む生分解性コーティング組成物
US7795467B1 (en) Bioabsorbable, biobeneficial polyurethanes for use in medical devices
CN103965455A (zh) 一种负载药物的可生物降解聚合物及其制备方法和应用
HK1188149A (en) Phase-separated block copolymer coatings for implantable medical devices

Legal Events

Date Code Title Description
RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20090728

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20090728

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100118

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100118

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120717

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20121017

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20121024

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20121119

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20121127

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20121217

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20130121

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20130212

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20160222

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees