JP5193460B2 - 飽和移転からのコントラスト強調を用いた試料特性の定量化 - Google Patents

飽和移転からのコントラスト強調を用いた試料特性の定量化 Download PDF

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JP5193460B2
JP5193460B2 JP2006332426A JP2006332426A JP5193460B2 JP 5193460 B2 JP5193460 B2 JP 5193460B2 JP 2006332426 A JP2006332426 A JP 2006332426A JP 2006332426 A JP2006332426 A JP 2006332426A JP 5193460 B2 JP5193460 B2 JP 5193460B2
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Japan
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cest
resonance
magnetization
intensity
pulse
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JP2006332426A
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Japanese (ja)
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JP2007152128A (ja
JP2007152128A5 (enExample
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ダブリュー・トーマス・ディクソン
イリーナ・ハンクー
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General Electric Co
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General Electric Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4804—Spatially selective measurement of temperature or pH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5605—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by transferring coherence or polarization from a spin species to another, e.g. creating magnetization transfer contrast [MTC], polarization transfer using nuclear Overhauser enhancement [NOE]

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  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2006332426A 2005-12-08 2006-12-08 飽和移転からのコントラスト強調を用いた試料特性の定量化 Expired - Fee Related JP5193460B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/297,263 US7610077B2 (en) 2005-12-08 2005-12-08 Quantitation of sample properties using contrast enhancement from saturation transfer
US11/297,263 2005-12-08

Publications (3)

Publication Number Publication Date
JP2007152128A JP2007152128A (ja) 2007-06-21
JP2007152128A5 JP2007152128A5 (enExample) 2011-01-27
JP5193460B2 true JP5193460B2 (ja) 2013-05-08

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Family Applications (1)

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JP2006332426A Expired - Fee Related JP5193460B2 (ja) 2005-12-08 2006-12-08 飽和移転からのコントラスト強調を用いた試料特性の定量化

Country Status (4)

Country Link
US (1) US7610077B2 (enExample)
JP (1) JP5193460B2 (enExample)
DE (1) DE102006058424A1 (enExample)
NL (1) NL1033025C2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0712326A2 (pt) * 2006-06-09 2012-01-10 Koninkl Philips Electronics Nv método para a obtenção de informação relativa ao parámetro fìsico-quìmico através da formação de imagens mri depois da administração a um paciente de um agente de contraste, produto de programa de computador, dispositivo de armazenagem dos dados legìveis por máquina, sistema para formação de imagem mri para uso com agente de contraste, agente de contraste, e, preparação
EP2205986B1 (en) * 2007-09-26 2013-07-03 The Johns Hopkins University Frequency referencing for chemical exchange saturation transfer (cest) mri
US8278925B2 (en) * 2008-03-26 2012-10-02 The General Hospital Corporation Method for relaxation-compensated fast multi-slice chemical exchange saturation transfer MRI
WO2009126289A2 (en) * 2008-04-09 2009-10-15 Beth Israel Deaconess Medical Center, Inc. Positive magnetic resonance imaging contrast methods and apparatus using chemical exchange saturation transfer
WO2010023132A1 (en) * 2008-08-26 2010-03-04 Bracco Imaging S.P.A. Mri-cest diagnostic technique based on non-punctual analysis
US8686727B2 (en) * 2010-07-20 2014-04-01 The Trustees Of The University Of Pennsylvania CEST MRI methods for imaging of metabolites and the use of same as biomarkers
WO2013082137A1 (en) * 2011-11-28 2013-06-06 New York University Apparatus, system, method and computer-readable medium for isolating chemical exchange saturation transfer contrast from magnetization transfer asymmetry under two-frequency rf irradiation
US9335393B2 (en) 2012-09-13 2016-05-10 Siemens Medical Solutions Usa, Inc. MR parallel imaging system reducing imaging time
WO2014165766A1 (en) * 2013-04-05 2014-10-09 The Trustees Of The University Of Pennsylvania Quantification of in vivo metabolite
US10267881B2 (en) 2014-12-18 2019-04-23 The Johns Hopkins University Multi-echo parametric variation saturation (MePaVARS CEST imaging and other MR imaging
JP7038671B2 (ja) * 2016-06-08 2022-03-18 シーダーズ－サイナイ メディカル センター 定量的化学交換飽和移動（ｑＣＥＳＴ）を用いた非侵襲性のｐＨ依存的イメージング
CN111722167B (zh) * 2019-03-19 2021-07-30 浙江大学 化学交换饱和转移-磁共振成像cest-mri序列生成方法、装置及可读存储介质

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4656400A (en) * 1999-04-21 2000-11-17 Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The Method for enhancing contrast produced by mri
EP1331012A1 (en) * 2002-01-29 2003-07-30 BRACCO IMAGING S.p.A. Responsive paramagnetic MRI contrast agents
US8639542B2 (en) * 2002-06-27 2014-01-28 Siebel Systems, Inc. Method and apparatus to facilitate development of a customer-specific business process model
US20070292354A1 (en) * 2004-09-23 2007-12-20 Guerbet Contrast Agents Encapsulating Systems for Cest Imaging
ATE455307T1 (de) * 2005-04-26 2010-01-15 Koninkl Philips Electronics Nv Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie
US8306603B2 (en) * 2005-04-26 2012-11-06 Koninklijke Philips Electronics N.V. MRI involving contrast agent with time modulated contrast enhancement

Also Published As

Publication number Publication date
US7610077B2 (en) 2009-10-27
JP2007152128A (ja) 2007-06-21
US20070134159A1 (en) 2007-06-14
NL1033025C2 (nl) 2010-05-21
NL1033025A1 (nl) 2007-06-11
DE102006058424A1 (de) 2007-07-19

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