ATE455307T1 - Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie - Google Patents

Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie

Info

Publication number
ATE455307T1
ATE455307T1 AT06727996T AT06727996T ATE455307T1 AT E455307 T1 ATE455307 T1 AT E455307T1 AT 06727996 T AT06727996 T AT 06727996T AT 06727996 T AT06727996 T AT 06727996T AT E455307 T1 ATE455307 T1 AT E455307T1
Authority
AT
Austria
Prior art keywords
magnetic resonance
contrast agents
resonance tomography
cest contrast
contrast agent
Prior art date
Application number
AT06727996T
Other languages
English (en)
Inventor
Rene Wegh
Jeroen Pikkemaat
Nicolaas Willard
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Application granted granted Critical
Publication of ATE455307T1 publication Critical patent/ATE455307T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4804—Spatially selective measurement of temperature or pH

Landscapes

  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT06727996T 2005-04-26 2006-04-21 Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie ATE455307T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05103355 2005-04-26
PCT/IB2006/051237 WO2006114739A2 (en) 2005-04-26 2006-04-21 Method for using cest contrast agents in mri

Publications (1)

Publication Number Publication Date
ATE455307T1 true ATE455307T1 (de) 2010-01-15

Family

ID=37215131

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06727996T ATE455307T1 (de) 2005-04-26 2006-04-21 Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie

Country Status (6)

Country Link
US (1) US7917188B2 (de)
EP (1) EP1889086B1 (de)
CN (1) CN101166987B (de)
AT (1) ATE455307T1 (de)
DE (1) DE602006011736D1 (de)
WO (1) WO2006114739A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7610077B2 (en) * 2005-12-08 2009-10-27 General Electric Compnay Quantitation of sample properties using contrast enhancement from saturation transfer
JP5371748B2 (ja) 2006-06-09 2013-12-18 コーニンクレッカ フィリップス エヌ ヴェ Ｍｒｉにおける造影剤濃度依存性の除去
EP2199815A1 (de) * 2008-12-22 2010-06-23 Koninklijke Philips Electronics N.V. MR-Bildgebung mit CEST-Kontrastverstärkung
US9157976B2 (en) * 2010-07-20 2015-10-13 The Trustees Of The University Of Pennsylvania CEST MRI methods for imaging glutaminolysis in cancer
US9327037B2 (en) 2011-02-08 2016-05-03 The Johns Hopkins University Mucus penetrating gene carriers
EP2515138A1 (de) * 2011-04-19 2012-10-24 Koninklijke Philips Electronics N.V. Bewegungsausgelöste Magnetresonanzbildgebung mit APT/CEST
DE102011078680B3 (de) * 2011-07-05 2012-12-20 Siemens Aktiengesellschaft Magnetfeldunempfindliche CEST-Bildgebung
WO2014124006A1 (en) * 2013-02-05 2014-08-14 The Johns Hopkins University Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof
US10335500B2 (en) 2014-05-12 2019-07-02 The Johns Hopkins University Highly stable biodegradable gene vector platforms for overcoming biological barriers
WO2016123125A1 (en) 2015-01-27 2016-08-04 The Johns Hopkins University Hypotonic hydrogel formulations for enhanced transport of active agents at mucosal surfaces
CN108369266B (zh) * 2015-12-23 2021-08-06 伯拉考成像股份公司 比率计量的脉冲cest成像
CN105759233B (zh) * 2016-03-04 2018-09-25 深圳先进技术研究院 一种快速化学交换饱和转移成像方法和系统

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746662B1 (en) 1999-02-09 2004-06-08 Board Of Regents The University Of Texas System pH sensitive MRI contrast agents
EP1178837A2 (de) * 1999-04-21 2002-02-13 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Verfahren zur verbesserung von kontrast mit mri
WO2002043775A2 (en) 2000-11-20 2002-06-06 GODFREY, Cullen, M. Paramagnetic metal ion-based macrocyclic contrast agents
US20040030239A1 (en) 2001-12-13 2004-02-12 The Johns Hopkins University School Of Medicine Method for MR/NMR imaging
AU2003209392B2 (en) 2002-01-24 2008-10-09 Barnes Jewish Hospital Integrin targeted imaging agents
EP1331012A1 (de) * 2002-01-29 2003-07-30 BRACCO IMAGING S.p.A. Magnetisch beeinflussbare paramagnetische Kontrastmittel für Magnetresonanzbildgebung
JP4355144B2 (ja) 2003-01-21 2009-10-28 学校法人日本大学 新規含窒素環状化合物

Also Published As

Publication number Publication date
US20080188738A1 (en) 2008-08-07
WO2006114739A2 (en) 2006-11-02
EP1889086B1 (de) 2010-01-13
EP1889086A2 (de) 2008-02-20
DE602006011736D1 (de) 2010-03-04
WO2006114739A3 (en) 2007-07-12
CN101166987A (zh) 2008-04-23
CN101166987B (zh) 2011-01-12
US7917188B2 (en) 2011-03-29

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