DE602006011736D1 - Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie - Google Patents

Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie

Info

Publication number
DE602006011736D1
DE602006011736D1 DE602006011736T DE602006011736T DE602006011736D1 DE 602006011736 D1 DE602006011736 D1 DE 602006011736D1 DE 602006011736 T DE602006011736 T DE 602006011736T DE 602006011736 T DE602006011736 T DE 602006011736T DE 602006011736 D1 DE602006011736 D1 DE 602006011736D1
Authority
DE
Germany
Prior art keywords
magnetic resonance
contrast agents
resonance tomography
cest contrast
contrast agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006011736T
Other languages
English (en)
Inventor
Rene T Wegh
Jeroen A Pikkemaat
Nicolaas P Willard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Philips Electronics NV filed Critical Koninklijke Philips Electronics NV
Publication of DE602006011736D1 publication Critical patent/DE602006011736D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4804—Spatially selective measurement of temperature or pH

Landscapes

  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE602006011736T 2005-04-26 2006-04-21 Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie Active DE602006011736D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05103355 2005-04-26
PCT/IB2006/051237 WO2006114739A2 (en) 2005-04-26 2006-04-21 Method for using cest contrast agents in mri

Publications (1)

Publication Number Publication Date
DE602006011736D1 true DE602006011736D1 (de) 2010-03-04

Family

ID=37215131

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006011736T Active DE602006011736D1 (de) 2005-04-26 2006-04-21 Verfahren zur verwendung von cest-kontrastmitteln bei der magnetresonanztomographie

Country Status (6)

Country Link
US (1) US7917188B2 (de)
EP (1) EP1889086B1 (de)
CN (1) CN101166987B (de)
AT (1) ATE455307T1 (de)
DE (1) DE602006011736D1 (de)
WO (1) WO2006114739A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7610077B2 (en) * 2005-12-08 2009-10-27 General Electric Compnay Quantitation of sample properties using contrast enhancement from saturation transfer
CN101466411B (zh) 2006-06-09 2014-12-24 皇家飞利浦电子股份有限公司 消除mri中的造影剂浓度依赖性
EP2199815A1 (de) * 2008-12-22 2010-06-23 Koninklijke Philips Electronics N.V. MR-Bildgebung mit CEST-Kontrastverstärkung
US9157976B2 (en) * 2010-07-20 2015-10-13 The Trustees Of The University Of Pennsylvania CEST MRI methods for imaging glutaminolysis in cancer
WO2012109363A2 (en) 2011-02-08 2012-08-16 The Johns Hopkins University Mucus penetrating gene carriers
EP2515138A1 (de) * 2011-04-19 2012-10-24 Koninklijke Philips Electronics N.V. Bewegungsausgelöste Magnetresonanzbildgebung mit APT/CEST
DE102011078680B3 (de) * 2011-07-05 2012-12-20 Siemens Aktiengesellschaft Magnetfeldunempfindliche CEST-Bildgebung
WO2014124006A1 (en) * 2013-02-05 2014-08-14 The Johns Hopkins University Nanoparticles for magnetic resonance imaging tracking and methods of making and using thereof
US10335500B2 (en) 2014-05-12 2019-07-02 The Johns Hopkins University Highly stable biodegradable gene vector platforms for overcoming biological barriers
JP6846351B2 (ja) 2015-01-27 2021-03-24 ザ・ジョンズ・ホプキンス・ユニバーシティー 粘膜表面における活性薬剤の増強された輸送のための低張ヒドロゲル製剤
CN108369266B (zh) * 2015-12-23 2021-08-06 伯拉考成像股份公司 比率计量的脉冲cest成像
CN105759233B (zh) * 2016-03-04 2018-09-25 深圳先进技术研究院 一种快速化学交换饱和转移成像方法和系统

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746662B1 (en) 1999-02-09 2004-06-08 Board Of Regents The University Of Texas System pH sensitive MRI contrast agents
WO2000066180A2 (en) 1999-04-21 2000-11-09 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The National Institutes Of Health Method for enhancing contrast produced by mri
WO2002043775A2 (en) 2000-11-20 2002-06-06 GODFREY, Cullen, M. Paramagnetic metal ion-based macrocyclic contrast agents
WO2003049604A2 (en) 2001-12-13 2003-06-19 The Johns Hopkins University School Of Medicine Method for mr/nmr imaging
EP1572639A4 (de) 2002-01-24 2006-08-09 Barnes Jewish Hospital Auf integrin zielende mittel zur bilddarstellung
EP1331012A1 (de) 2002-01-29 2003-07-30 BRACCO IMAGING S.p.A. Magnetisch beeinflussbare paramagnetische Kontrastmittel für Magnetresonanzbildgebung
JP4355144B2 (ja) 2003-01-21 2009-10-28 学校法人日本大学 新規含窒素環状化合物

Also Published As

Publication number Publication date
US7917188B2 (en) 2011-03-29
CN101166987A (zh) 2008-04-23
EP1889086B1 (de) 2010-01-13
EP1889086A2 (de) 2008-02-20
WO2006114739A2 (en) 2006-11-02
US20080188738A1 (en) 2008-08-07
CN101166987B (zh) 2011-01-12
ATE455307T1 (de) 2010-01-15
WO2006114739A3 (en) 2007-07-12

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Representative=s name: VOLMER, G., DIPL.-ING., PAT.-ANW., 52066 AACHEN

8364 No opposition during term of opposition