JP5015606B2 - モレキュラーイメージング用の超音波造影剤 - Google Patents

モレキュラーイメージング用の超音波造影剤 Download PDF

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Publication number
JP5015606B2
JP5015606B2 JP2006548524A JP2006548524A JP5015606B2 JP 5015606 B2 JP5015606 B2 JP 5015606B2 JP 2006548524 A JP2006548524 A JP 2006548524A JP 2006548524 A JP2006548524 A JP 2006548524A JP 5015606 B2 JP5015606 B2 JP 5015606B2
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Prior art keywords
contrast agent
agent according
ultrasound contrast
metal
ultrasound
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JP2006548524A
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Japanese (ja)
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JP2007517858A (ja
JP2007517858A5 (enExample
Inventor
ボンメル ティース ファン
ニコラース ペトゥルス ウィラード
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Koninklijke Philips NV
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Koninklijke Philips NV
Koninklijke Philips Electronics NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/225—Microparticles, microcapsules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
JP2006548524A 2004-01-15 2005-01-06 モレキュラーイメージング用の超音波造影剤 Expired - Fee Related JP5015606B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04100117 2004-01-15
EP04100117.3 2004-01-15
PCT/IB2005/050075 WO2005070473A1 (en) 2004-01-15 2005-01-06 Ultrasound contrast agents for molecular imaging

Publications (3)

Publication Number Publication Date
JP2007517858A JP2007517858A (ja) 2007-07-05
JP2007517858A5 JP2007517858A5 (enExample) 2011-03-31
JP5015606B2 true JP5015606B2 (ja) 2012-08-29

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006548524A Expired - Fee Related JP5015606B2 (ja) 2004-01-15 2005-01-06 モレキュラーイメージング用の超音波造影剤

Country Status (5)

Country Link
US (1) US20070003482A1 (enExample)
EP (1) EP1711211A1 (enExample)
JP (1) JP5015606B2 (enExample)
CN (1) CN1909931B (enExample)
WO (1) WO2005070473A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090148385A1 (en) * 2004-11-19 2009-06-11 Koninklijke Philips Electronics, N.V. Ultrasound Contrast Agents For Molecular Imaging
NO20052429D0 (no) * 2005-05-20 2005-05-20 Amersham Health As Konstrastmidler
US9149545B2 (en) 2005-11-02 2015-10-06 General Electric Company Nanoparticle-based imaging agents for X-ray/computed tomography and methods for making same
WO2008101019A2 (en) * 2007-02-13 2008-08-21 Board Of Regents, The University Of Texas System Molecular specific photoacoustic imaging
JP5689416B2 (ja) * 2008-07-23 2015-03-25 コーニンクレッカ フィリップス エヌ ヴェ 超音波仲介による薬送達
WO2011097824A1 (zh) * 2010-02-12 2011-08-18 大连科林爱纳米科技有限公司 X射线或者ct造影剂用金纳米粒子的制造方法
RU2444296C2 (ru) * 2010-03-24 2012-03-10 Государственное образовательное учреждение высшего профессионального образования "Уральская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО УГМА Росздрава) Способ использования суспензий наночастиц оксидов металлов в качестве контрастных веществ для ультразвуковой визуализации сердца и сосудов
CN103083687B (zh) * 2013-01-16 2016-04-13 东南大学 一种银、铂纳米簇在肿瘤靶向成像的应用
CN103100093B (zh) * 2013-01-23 2015-05-06 中山大学附属第三医院 一种负载小干扰rna的纳米级脂质微泡超声造影剂及制备方法
JP7116563B2 (ja) * 2018-03-16 2022-08-10 株式会社日本触媒 複合粒子
TW202131955A (zh) * 2019-10-17 2021-09-01 中央研究院 用以增加超音波影像於診斷腫瘤的準確度或敏感度的方法
CN116650677B (zh) * 2023-04-06 2025-11-07 上海瑞凝生物科技有限公司 一种超声显影水凝胶及其制备方法和应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4572203A (en) * 1983-01-27 1986-02-25 Feinstein Steven B Contact agents for ultrasonic imaging
PT81498B (pt) 1984-11-23 1987-12-30 Schering Ag Processo para a preparacao de composicoes para diagnostico contendo particulas magneticas
US4904497A (en) 1987-03-16 1990-02-27 Olin Corporation Electromagnetic solder tinning method
US5310539A (en) * 1991-04-15 1994-05-10 Board Of Regents, The University Of Texas System Melanin-based agents for image enhancement
DE4117782C2 (de) * 1991-05-28 1997-07-17 Diagnostikforschung Inst Nanokristalline magnetische Eisenoxid-Partikel, Verfahren zu ihrer Herstellung sowie diagnostische und/oder therapeutische Mittel
DE4140900A1 (de) * 1991-12-12 1993-06-17 Basf Ag Als carrier fuer die elektrophotographie geeignete teilchen
US5411730A (en) * 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
US6818199B1 (en) * 1994-07-29 2004-11-16 James F. Hainfeld Media and methods for enhanced medical imaging
EP0941128B1 (en) * 1996-11-06 2004-10-13 STS Biopolymers, Inc. Echogenic coating containing gaseous spaces for ultrasonography
JPH10206403A (ja) * 1997-01-22 1998-08-07 Hitachi Constr Mach Co Ltd 試料表面処理法および試料表面処理剤
JPH10330288A (ja) * 1997-06-03 1998-12-15 Mitsubishi Chem Corp 金属微粒子複合体及びこれを利用した造影剤
US6165440A (en) * 1997-07-09 2000-12-26 Board Of Regents, The University Of Texas System Radiation and nanoparticles for enhancement of drug delivery in solid tumors
WO2000006244A2 (en) 1998-07-30 2000-02-10 Hainfeld James F Loading metal particles into cell membrane vesicles and metal particle use for imaging and therapy
US6254852B1 (en) * 1999-07-16 2001-07-03 Dupont Pharmaceuticals Company Porous inorganic targeted ultrasound contrast agents
US6530944B2 (en) * 2000-02-08 2003-03-11 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
DE10037832C2 (de) 2000-08-03 2003-08-21 Karlsruhe Forschzent Kontrastmittel für medizinische Diagnostik und dessen Verwendung
US6797257B2 (en) 2001-06-26 2004-09-28 The Board Of Trustees Of The University Of Illinois Paramagnetic polymerized protein microspheres and methods of preparation thereof
WO2003062372A2 (en) * 2001-10-02 2003-07-31 The Regents Of The University Of California Nanoparticle assembled hollow spheres
AU2002351240A1 (en) * 2002-03-08 2003-09-22 James Hainfeld Gold nanoparticles used for x-rays imaging
US7500953B2 (en) * 2003-01-25 2009-03-10 Seno Medical Instruments, Inc. High contrast optoacoustic imaging using nanoparticles
US20070081946A1 (en) * 2003-12-22 2007-04-12 Bracco Research S.A. Assembly of gas-filled microvesicle with active component for contrast imaging
WO2005113705A1 (en) * 2004-05-21 2005-12-01 Oxonica Limited Composite luminescent particles

Also Published As

Publication number Publication date
WO2005070473A1 (en) 2005-08-04
EP1711211A1 (en) 2006-10-18
JP2007517858A (ja) 2007-07-05
CN1909931B (zh) 2011-01-12
US20070003482A1 (en) 2007-01-04
CN1909931A (zh) 2007-02-07

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