CN1909931B - 用于分子成像的超声造影剂 - Google Patents

用于分子成像的超声造影剂 Download PDF

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Publication number
CN1909931B
CN1909931B CN2005800023483A CN200580002348A CN1909931B CN 1909931 B CN1909931 B CN 1909931B CN 2005800023483 A CN2005800023483 A CN 2005800023483A CN 200580002348 A CN200580002348 A CN 200580002348A CN 1909931 B CN1909931 B CN 1909931B
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China
Prior art keywords
metal
use according
metal nanoparticles
nanoparticles
layer
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Expired - Fee Related
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CN2005800023483A
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English (en)
Chinese (zh)
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CN1909931A (zh
Inventor
T·范博梅尔
N·P·威拉德
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Koninklijke Philips NV
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Koninklijke Philips Electronics NV
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/225—Microparticles, microcapsules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
CN2005800023483A 2004-01-15 2005-01-06 用于分子成像的超声造影剂 Expired - Fee Related CN1909931B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04100117 2004-01-15
EP04100117.3 2004-01-15
PCT/IB2005/050075 WO2005070473A1 (en) 2004-01-15 2005-01-06 Ultrasound contrast agents for molecular imaging

Publications (2)

Publication Number Publication Date
CN1909931A CN1909931A (zh) 2007-02-07
CN1909931B true CN1909931B (zh) 2011-01-12

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Family Applications (1)

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CN2005800023483A Expired - Fee Related CN1909931B (zh) 2004-01-15 2005-01-06 用于分子成像的超声造影剂

Country Status (5)

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US (1) US20070003482A1 (enExample)
EP (1) EP1711211A1 (enExample)
JP (1) JP5015606B2 (enExample)
CN (1) CN1909931B (enExample)
WO (1) WO2005070473A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090148385A1 (en) * 2004-11-19 2009-06-11 Koninklijke Philips Electronics, N.V. Ultrasound Contrast Agents For Molecular Imaging
NO20052429D0 (no) * 2005-05-20 2005-05-20 Amersham Health As Konstrastmidler
US9149545B2 (en) 2005-11-02 2015-10-06 General Electric Company Nanoparticle-based imaging agents for X-ray/computed tomography and methods for making same
WO2008101019A2 (en) * 2007-02-13 2008-08-21 Board Of Regents, The University Of Texas System Molecular specific photoacoustic imaging
JP5689416B2 (ja) * 2008-07-23 2015-03-25 コーニンクレッカ フィリップス エヌ ヴェ 超音波仲介による薬送達
WO2011097824A1 (zh) * 2010-02-12 2011-08-18 大连科林爱纳米科技有限公司 X射线或者ct造影剂用金纳米粒子的制造方法
RU2444296C2 (ru) * 2010-03-24 2012-03-10 Государственное образовательное учреждение высшего профессионального образования "Уральская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО УГМА Росздрава) Способ использования суспензий наночастиц оксидов металлов в качестве контрастных веществ для ультразвуковой визуализации сердца и сосудов
CN103083687B (zh) * 2013-01-16 2016-04-13 东南大学 一种银、铂纳米簇在肿瘤靶向成像的应用
CN103100093B (zh) * 2013-01-23 2015-05-06 中山大学附属第三医院 一种负载小干扰rna的纳米级脂质微泡超声造影剂及制备方法
JP7116563B2 (ja) * 2018-03-16 2022-08-10 株式会社日本触媒 複合粒子
TW202131955A (zh) * 2019-10-17 2021-09-01 中央研究院 用以增加超音波影像於診斷腫瘤的準確度或敏感度的方法
CN116650677B (zh) * 2023-04-06 2025-11-07 上海瑞凝生物科技有限公司 一种超声显影水凝胶及其制备方法和应用

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DE4117782C2 (de) * 1991-05-28 1997-07-17 Diagnostikforschung Inst Nanokristalline magnetische Eisenoxid-Partikel, Verfahren zu ihrer Herstellung sowie diagnostische und/oder therapeutische Mittel
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US5411730A (en) * 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
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EP0941128B1 (en) * 1996-11-06 2004-10-13 STS Biopolymers, Inc. Echogenic coating containing gaseous spaces for ultrasonography
JPH10206403A (ja) * 1997-01-22 1998-08-07 Hitachi Constr Mach Co Ltd 試料表面処理法および試料表面処理剤
JPH10330288A (ja) * 1997-06-03 1998-12-15 Mitsubishi Chem Corp 金属微粒子複合体及びこれを利用した造影剤
US6165440A (en) * 1997-07-09 2000-12-26 Board Of Regents, The University Of Texas System Radiation and nanoparticles for enhancement of drug delivery in solid tumors
WO2000006244A2 (en) 1998-07-30 2000-02-10 Hainfeld James F Loading metal particles into cell membrane vesicles and metal particle use for imaging and therapy
US6254852B1 (en) * 1999-07-16 2001-07-03 Dupont Pharmaceuticals Company Porous inorganic targeted ultrasound contrast agents
US6530944B2 (en) * 2000-02-08 2003-03-11 Rice University Optically-active nanoparticles for use in therapeutic and diagnostic methods
DE10037832C2 (de) 2000-08-03 2003-08-21 Karlsruhe Forschzent Kontrastmittel für medizinische Diagnostik und dessen Verwendung
US6797257B2 (en) 2001-06-26 2004-09-28 The Board Of Trustees Of The University Of Illinois Paramagnetic polymerized protein microspheres and methods of preparation thereof
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Title
WEITSCHIES W et al.Partikulaere kontrastmittel zur intravasalen applikation.PHARMAZEUTISCHE ZEITUNG, FRANKFURT, DE140 38.1995,140(38),9-16.
WEITSCHIES W et al.Partikulaere kontrastmittel zur intravasalen applikation.PHARMAZEUTISCHE ZEITUNG, FRANKFURT, DE140 38.1995,140(38),9-16. *

Also Published As

Publication number Publication date
WO2005070473A1 (en) 2005-08-04
EP1711211A1 (en) 2006-10-18
JP2007517858A (ja) 2007-07-05
US20070003482A1 (en) 2007-01-04
CN1909931A (zh) 2007-02-07
JP5015606B2 (ja) 2012-08-29

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