JP4994570B2 - 胃保持制御ドラッグデリバリーシステム - Google Patents

胃保持制御ドラッグデリバリーシステム Download PDF

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Publication number
JP4994570B2
JP4994570B2 JP2003516487A JP2003516487A JP4994570B2 JP 4994570 B2 JP4994570 B2 JP 4994570B2 JP 2003516487 A JP2003516487 A JP 2003516487A JP 2003516487 A JP2003516487 A JP 2003516487A JP 4994570 B2 JP4994570 B2 JP 4994570B2
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Prior art keywords
delivery system
drug delivery
gastric retention
core
controlled drug
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Japanese (ja)
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JP2004538301A (ja
JP2004538301A5 (enExample
Inventor
カムレシュ・モハンラル・ドゥダラ
ニティン・バラチャンドラ・ダルマディカリ
ヴァイシャリ・ヴィジャイ・ダヴセ
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サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2003516487A 2001-07-04 2002-07-04 胃保持制御ドラッグデリバリーシステム Expired - Fee Related JP4994570B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN612/MUM/2001 2001-07-04
IN612MU2001 2001-07-04
PCT/IN2002/000144 WO2003011255A1 (en) 2001-07-04 2002-07-04 Gastric retention controlled drug delivery system

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009281402A Division JP2010090161A (ja) 2001-07-04 2009-12-11 胃保持制御ドラッグデリバリーシステム

Publications (3)

Publication Number Publication Date
JP2004538301A JP2004538301A (ja) 2004-12-24
JP2004538301A5 JP2004538301A5 (enExample) 2006-01-05
JP4994570B2 true JP4994570B2 (ja) 2012-08-08

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Family Applications (2)

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JP2003516487A Expired - Fee Related JP4994570B2 (ja) 2001-07-04 2002-07-04 胃保持制御ドラッグデリバリーシステム
JP2009281402A Pending JP2010090161A (ja) 2001-07-04 2009-12-11 胃保持制御ドラッグデリバリーシステム

Family Applications After (1)

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JP2009281402A Pending JP2010090161A (ja) 2001-07-04 2009-12-11 胃保持制御ドラッグデリバリーシステム

Country Status (17)

Country Link
US (2) US7776345B2 (enExample)
EP (2) EP2238975B1 (enExample)
JP (2) JP4994570B2 (enExample)
KR (1) KR20040018394A (enExample)
CN (1) CN1520286B (enExample)
AT (1) ATE477795T1 (enExample)
AU (1) AU2002355686B2 (enExample)
BR (1) BR0211317A (enExample)
CA (1) CA2452738C (enExample)
DE (1) DE60237372D1 (enExample)
ES (1) ES2398348T3 (enExample)
HU (1) HUP0500795A3 (enExample)
MX (1) MXPA03012041A (enExample)
PL (1) PL370793A1 (enExample)
RU (1) RU2325152C2 (enExample)
WO (1) WO2003011255A1 (enExample)
ZA (1) ZA200400799B (enExample)

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RU2325152C2 (ru) 2008-05-27
BR0211317A (pt) 2004-12-14
ZA200400799B (en) 2005-07-27
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