JP4954378B2 - ４，５−ジアミノシキミ酸誘導体の調製方法 - Google Patents

４，５−ジアミノシキミ酸誘導体の調製方法 Download PDF

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Publication number
JP4954378B2
JP4954378B2 JP2001039289A JP2001039289A JP4954378B2 JP 4954378 B2 JP4954378 B2 JP 4954378B2 JP 2001039289 A JP2001039289 A JP 2001039289A JP 2001039289 A JP2001039289 A JP 2001039289A JP 4954378 B2 JP4954378 B2 JP 4954378B2
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JP
Japan
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formula
compound
acid
azide
ethyl
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Expired - Fee Related
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English (en)
Japanese (ja)
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JP2001288152A (ja
Inventor
シュテファン・アブレヒト
マルチン・カルプ
レネ・トリュサルディ
ビート・ヴィルツ
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/52—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/26—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
JP2001039289A 2000-02-22 2001-02-16 ４，５−ジアミノシキミ酸誘導体の調製方法 Expired - Fee Related JP4954378B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00103673.0 2000-02-22
EP00103673 2000-02-22

Publications (2)

Publication Number Publication Date
JP2001288152A JP2001288152A (ja) 2001-10-16
JP4954378B2 true JP4954378B2 (ja) 2012-06-13

Family

ID=8167922

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001039289A Expired - Fee Related JP4954378B2 (ja) 2000-02-22 2001-02-16 ４，５−ジアミノシキミ酸誘導体の調製方法

Country Status (13)

Country Link
US (1) US6403824B2 (enExample)
EP (1) EP1127872B1 (enExample)
JP (1) JP4954378B2 (enExample)
KR (1) KR100743305B1 (enExample)
CN (1) CN1280258C (enExample)
AT (1) ATE316952T1 (enExample)
CA (1) CA2337452C (enExample)
DE (1) DE60116909T2 (enExample)
DK (1) DK1127872T3 (enExample)
ES (1) ES2256096T3 (enExample)
IN (1) IN192890B (enExample)
JO (1) JO2251B1 (enExample)
PT (1) PT1127872E (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6518048B2 (en) * 2000-04-10 2003-02-11 Hoffmann-La Roche Inc. Stereo-specific synthesis of shimikic acid derivatives with improved efficiency
US7122684B2 (en) 2003-03-13 2006-10-17 Roche Colorado Corporation Process for preparing 1,2-diamino compounds
EP1602730A3 (en) * 2004-06-04 2006-01-25 DSM IP Assets B.V. Biosynthetic production of 4-amino-4-deoxychorismate (ADC) and [3R,4R]-4-amino-3-hydroxycyclohexa-1,5-diene-1-carboxylic acid (3,4-CHA)
DK1791808T3 (da) * 2004-09-02 2010-08-09 Hoffmann La Roche Fremgangsmåde til fremstilling af 4,5-diaminoshikiminsyre
US7977077B2 (en) 2006-01-30 2011-07-12 Board Of Trustees Of Michigan State University Synthesis of intermediates of oseltamivir carboxylates
US20080009639A1 (en) * 2006-07-10 2008-01-10 Apotex Pharmachem Inc. Preparation of oseltamivir phosphate (Tamiflu) and intermediates starting from D-glucose or D-xylose
WO2008077809A1 (en) * 2006-12-22 2008-07-03 F. Hoffmann-La Roche Ag Process for the manufacture of 7-oxa-bicyclo derivatives
CN101801914B (zh) 2007-09-18 2013-06-05 弗·哈夫曼-拉罗切有限公司 从莽草酸生成磷酸奥司他韦的方法
KR101049475B1 (ko) * 2008-12-22 2011-07-15 (주)팜스웰바이오 아자-바이사이클로[2.2.1]헵텐 유도체, 이의 제조방법 및 이를 이용한 오셀타미비르의 중간체의 제조방법
JP5796762B2 (ja) * 2010-10-18 2015-10-21 国立大学法人豊橋技術科学大学 光学活性なシクロヘキセン誘導体の製造方法
CN102464596A (zh) * 2010-11-10 2012-05-23 南开大学 “一锅法”获得达菲合成反应的关键中间体
US9834796B2 (en) 2011-09-07 2017-12-05 Shinshu University Method for producing useful metabolite from filamentous fungus
CN105801445B (zh) * 2016-04-13 2017-08-25 福建师范大学 一种具有抗菌活性的非蛋白质氨基酸及其制备方法
US10385010B1 (en) * 2018-03-28 2019-08-20 Georgia State University Research Foundation, Inc. Expedient synthesis of oseltamivir and related compounds via direct olefin diazidation-diamidation reaction

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69711395T2 (de) 1996-08-23 2002-11-07 Gilead Sciences, Inc. Verfahren zur herstellung von cyclohexen-carboxylatderivate
CN1272105A (zh) 1997-09-17 2000-11-01 吉里德科学公司 含六元环的化合物,其制备方法及其作为药物的用途
BR0010525A (pt) 1999-10-19 2002-11-26 Abbott Lab cido 1-ciclo-hexeno-1-carboxìlico e 1-ciclo-hexeno-1carboxilatos como inibidores de neuraminidase

Also Published As

Publication number Publication date
KR100743305B1 (ko) 2007-07-26
CN1280258C (zh) 2006-10-18
US6403824B2 (en) 2002-06-11
DK1127872T3 (da) 2006-06-12
EP1127872B1 (en) 2006-02-01
JP2001288152A (ja) 2001-10-16
EP1127872A1 (en) 2001-08-29
KR20010083189A (ko) 2001-08-31
IN192890B (enExample) 2004-05-29
DE60116909T2 (de) 2006-09-28
DE60116909D1 (de) 2006-04-13
CA2337452C (en) 2008-04-15
JO2251B1 (en) 2004-10-07
ATE316952T1 (de) 2006-02-15
ES2256096T3 (es) 2006-07-16
PT1127872E (pt) 2006-06-30
CA2337452A1 (en) 2001-08-22
US20020006960A1 (en) 2002-01-17
CN1310170A (zh) 2001-08-29

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