JP4949473B2 - 肝機能を評価するためのバイオマーカー - Google Patents

肝機能を評価するためのバイオマーカー Download PDF

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Publication number
JP4949473B2
JP4949473B2 JP2009527200A JP2009527200A JP4949473B2 JP 4949473 B2 JP4949473 B2 JP 4949473B2 JP 2009527200 A JP2009527200 A JP 2009527200A JP 2009527200 A JP2009527200 A JP 2009527200A JP 4949473 B2 JP4949473 B2 JP 4949473B2
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JP
Japan
Prior art keywords
liver
individual
patients
adma
liver disease
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JP2009527200A
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English (en)
Japanese (ja)
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JP2010502979A (ja
JP2010502979A5 (enExample
Inventor
ジャラン,ラジーヴ
ピー ムケルジー,ラジェシュワル
デーヴィス,ネイサン
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UCL Business Ltd
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UCL Biomedica PLC
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/76—Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
    • G01N2333/765—Serum albumin, e.g. HSA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/08—Hepato-biliairy disorders other than hepatitis
    • G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
JP2009527200A 2006-09-07 2007-09-07 肝機能を評価するためのバイオマーカー Active JP4949473B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0617581.4 2006-09-07
GBGB0617581.4A GB0617581D0 (en) 2006-09-07 2006-09-07 Biomarkers for assessing liver function
PCT/GB2007/003362 WO2008029145A1 (en) 2006-09-07 2007-09-07 Biqmarkers for assessing liver function

Publications (3)

Publication Number Publication Date
JP2010502979A JP2010502979A (ja) 2010-01-28
JP2010502979A5 JP2010502979A5 (enExample) 2010-10-21
JP4949473B2 true JP4949473B2 (ja) 2012-06-06

Family

ID=37232490

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009527200A Active JP4949473B2 (ja) 2006-09-07 2007-09-07 肝機能を評価するためのバイオマーカー

Country Status (16)

Country Link
US (1) US8455220B2 (enExample)
EP (1) EP2059817B1 (enExample)
JP (1) JP4949473B2 (enExample)
KR (1) KR20090083335A (enExample)
AT (1) ATE488772T1 (enExample)
AU (1) AU2007293302A1 (enExample)
CA (1) CA2662597A1 (enExample)
DE (1) DE602007010644D1 (enExample)
EA (1) EA200970256A1 (enExample)
ES (1) ES2353835T3 (enExample)
GB (1) GB0617581D0 (enExample)
IL (1) IL197271A0 (enExample)
MX (1) MX2009002378A (enExample)
NO (1) NO20090993L (enExample)
WO (1) WO2008029145A1 (enExample)
ZA (1) ZA200901432B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2823349T3 (es) 2011-05-31 2021-05-06 Univ Colorado Regents Procedimiento para evaluación de la función hepática y el flujo sanguíneo portal
CA2891281C (en) 2012-11-12 2023-11-28 The Regents Of The University Of Colorado, A Body Corporate Disease severity index for assessment of chronic liver disease and method for diagnosis of three distinct subtypes of primary sclerosing cholangitis
WO2014190170A1 (en) * 2013-05-22 2014-11-27 The Regents Of The University Of California Biomarker composite test for hepatic vein pressure gradient and cirrhosis treatment
AU2015335855A1 (en) * 2014-10-24 2017-05-18 Mallinckrodt Hospital Products IP Limited Method of treating patients with hepatorenal syndrome type 1
CN105181692A (zh) * 2015-09-30 2015-12-23 山东博科生物产业有限公司 一种缺血修饰白蛋白比色法检测试剂盒
WO2017081073A1 (en) * 2015-11-10 2017-05-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time of patients with decompensated alcoholic cirrhosis
US20220018852A1 (en) * 2018-11-20 2022-01-20 Inserm (Institute National De Ka Santé Et De La Recherche Médicale) Methods and kits for detecting liver dysfunction in a subject
CN121331222B (zh) * 2025-12-15 2026-03-10 北京大学 基于蛋白质组的慢性肝脏疾病发病预测的蛋白组合、预测模型及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2340397A (en) 1996-03-21 1997-10-10 Mayo Foundation For Medical Education And Research Use of nicotine to treat liver disease
WO2002004465A1 (en) 2000-07-06 2002-01-17 Fal Diagnostics Methods and kits for the detection of arginine compounds
US7063782B2 (en) * 2001-11-26 2006-06-20 Ischemia Technologies, Inc. Electrochemical detection of ischemia
AU2003261424A1 (en) * 2002-08-06 2004-02-23 Nitromed, Inc. Nitrosated and/or nitrosylated ursodeoxycholic acid compounds, compositions and methods of use
WO2004046314A2 (en) 2002-11-15 2004-06-03 The Board Of Trustees Of The Leland Stanford Junior University Methods for detecting asymmetric dimethylarginine in a biological sample
WO2005039598A1 (en) 2003-10-24 2005-05-06 Intermune, Inc. Method of treating alcoholic liver disease
DE10351238A1 (de) * 2003-11-03 2005-06-02 Roche Diagnostics Gmbh Diagnosestellung von akuten myokardialen, ischämischen Erkrankungen durch Kombination von Markern

Also Published As

Publication number Publication date
JP2010502979A (ja) 2010-01-28
IL197271A0 (en) 2009-12-24
EP2059817B1 (en) 2010-11-17
US20090280519A1 (en) 2009-11-12
DE602007010644D1 (de) 2010-12-30
CA2662597A1 (en) 2008-03-13
ZA200901432B (en) 2010-06-30
EP2059817A1 (en) 2009-05-20
KR20090083335A (ko) 2009-08-03
ES2353835T3 (es) 2011-03-07
MX2009002378A (es) 2009-03-20
AU2007293302A1 (en) 2008-03-13
NO20090993L (no) 2009-04-03
WO2008029145A1 (en) 2008-03-13
GB0617581D0 (en) 2006-10-18
EA200970256A1 (ru) 2009-08-28
ATE488772T1 (de) 2010-12-15
US8455220B2 (en) 2013-06-04

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