ES2353835T3 - Biomarcadores para evaluar la función hepática. - Google Patents

Biomarcadores para evaluar la función hepática. Download PDF

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Publication number
ES2353835T3
ES2353835T3 ES07804163T ES07804163T ES2353835T3 ES 2353835 T3 ES2353835 T3 ES 2353835T3 ES 07804163 T ES07804163 T ES 07804163T ES 07804163 T ES07804163 T ES 07804163T ES 2353835 T3 ES2353835 T3 ES 2353835T3
Authority
ES
Spain
Prior art keywords
liver
individual
patients
liver disease
adma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07804163T
Other languages
English (en)
Spanish (es)
Inventor
Rajiv Jalan
Rajeshwar P Mookerjee
Nathan Davies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCL Business Ltd
Original Assignee
UCL Business Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCL Business Ltd filed Critical UCL Business Ltd
Application granted granted Critical
Publication of ES2353835T3 publication Critical patent/ES2353835T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/76Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
    • G01N2333/765Serum albumin, e.g. HSA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/08Hepato-biliairy disorders other than hepatitis
    • G01N2800/085Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES07804163T 2006-09-07 2007-09-07 Biomarcadores para evaluar la función hepática. Active ES2353835T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0617581 2006-09-07
GBGB0617581.4A GB0617581D0 (en) 2006-09-07 2006-09-07 Biomarkers for assessing liver function

Publications (1)

Publication Number Publication Date
ES2353835T3 true ES2353835T3 (es) 2011-03-07

Family

ID=37232490

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07804163T Active ES2353835T3 (es) 2006-09-07 2007-09-07 Biomarcadores para evaluar la función hepática.

Country Status (16)

Country Link
US (1) US8455220B2 (enExample)
EP (1) EP2059817B1 (enExample)
JP (1) JP4949473B2 (enExample)
KR (1) KR20090083335A (enExample)
AT (1) ATE488772T1 (enExample)
AU (1) AU2007293302A1 (enExample)
CA (1) CA2662597A1 (enExample)
DE (1) DE602007010644D1 (enExample)
EA (1) EA200970256A1 (enExample)
ES (1) ES2353835T3 (enExample)
GB (1) GB0617581D0 (enExample)
IL (1) IL197271A0 (enExample)
MX (1) MX2009002378A (enExample)
NO (1) NO20090993L (enExample)
WO (1) WO2008029145A1 (enExample)
ZA (1) ZA200901432B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2715346B1 (en) 2011-05-31 2020-07-15 The Regents of the University of Colorado, A Body Corporate Method for assessment of hepatic function and portal blood flow
CA2891281C (en) * 2012-11-12 2023-11-28 The Regents Of The University Of Colorado, A Body Corporate Disease severity index for assessment of chronic liver disease and method for diagnosis of three distinct subtypes of primary sclerosing cholangitis
WO2014190170A1 (en) * 2013-05-22 2014-11-27 The Regents Of The University Of California Biomarker composite test for hepatic vein pressure gradient and cirrhosis treatment
CN107206049B (zh) * 2014-10-24 2021-12-07 马林克罗特医疗产品知识产权公司 治疗患1型肝肾综合征的患者的方法
CN105181692A (zh) * 2015-09-30 2015-12-23 山东博科生物产业有限公司 一种缺血修饰白蛋白比色法检测试剂盒
WO2017081073A1 (en) * 2015-11-10 2017-05-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the survival time of patients with decompensated alcoholic cirrhosis
WO2020104458A1 (en) * 2018-11-20 2020-05-28 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for detecting liver dysfunction in a subject
CN121331222B (zh) * 2025-12-15 2026-03-10 北京大学 基于蛋白质组的慢性肝脏疾病发病预测的蛋白组合、预测模型及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2340397A (en) 1996-03-21 1997-10-10 Mayo Foundation For Medical Education And Research Use of nicotine to treat liver disease
EP1299398A1 (en) 2000-07-06 2003-04-09 Fal Diagnostics Methods and kits for the detection of arginine compounds
AU2002352959B2 (en) * 2001-11-26 2008-04-10 Ischemia Technologies, Inc. Electrochemical detection of ischemia
WO2004012686A2 (en) * 2002-08-06 2004-02-12 Nitromed, Inc. Nitrosated and/or nitrosylated ursodeoxycholic acid compounds, compositions and methods of use
AU2003290784A1 (en) 2002-11-15 2004-06-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for detecting asymmetric dimethylarginine in a biological sample
WO2005039598A1 (en) 2003-10-24 2005-05-06 Intermune, Inc. Method of treating alcoholic liver disease
DE10351238A1 (de) * 2003-11-03 2005-06-02 Roche Diagnostics Gmbh Diagnosestellung von akuten myokardialen, ischämischen Erkrankungen durch Kombination von Markern

Also Published As

Publication number Publication date
EA200970256A1 (ru) 2009-08-28
US8455220B2 (en) 2013-06-04
EP2059817A1 (en) 2009-05-20
ATE488772T1 (de) 2010-12-15
US20090280519A1 (en) 2009-11-12
WO2008029145A1 (en) 2008-03-13
JP2010502979A (ja) 2010-01-28
CA2662597A1 (en) 2008-03-13
NO20090993L (no) 2009-04-03
ZA200901432B (en) 2010-06-30
GB0617581D0 (en) 2006-10-18
MX2009002378A (es) 2009-03-20
DE602007010644D1 (de) 2010-12-30
EP2059817B1 (en) 2010-11-17
KR20090083335A (ko) 2009-08-03
JP4949473B2 (ja) 2012-06-06
AU2007293302A1 (en) 2008-03-13
IL197271A0 (en) 2009-12-24

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