JP4940438B2 - 疎水性薬物検出法 - Google Patents

疎水性薬物検出法 Download PDF

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Publication number
JP4940438B2
JP4940438B2 JP2010538187A JP2010538187A JP4940438B2 JP 4940438 B2 JP4940438 B2 JP 4940438B2 JP 2010538187 A JP2010538187 A JP 2010538187A JP 2010538187 A JP2010538187 A JP 2010538187A JP 4940438 B2 JP4940438 B2 JP 4940438B2
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Prior art keywords
hydrophobic drug
drug
medium
antibody
hydrophobic
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Japanese (ja)
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JP2011506973A (ja
JP2011506973A5 (enExample
Inventor
ウェイ,ティエ・キュー
クレイグ,アラン
ポージー,エイミー
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シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493Immunosupressants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/962Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497Preparation composition [e.g., lysing or precipitation, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331Preservative, buffer, anticoagulant or diluent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125Digestion or removing interfering materials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2525Stabilizing or preserving
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25625Dilution

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2010538187A 2007-12-14 2008-12-12 疎水性薬物検出法 Active JP4940438B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/956,603 US7910378B2 (en) 2007-12-14 2007-12-14 Methods for detection of hydrophobic drugs
US11/956,603 2007-12-14
PCT/US2008/086602 WO2009079374A1 (en) 2007-12-14 2008-12-12 Methods for detection of hydrophobic drugs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012021160A Division JP5571108B2 (ja) 2007-12-14 2012-02-02 疎水性薬物検出法

Publications (3)

Publication Number Publication Date
JP2011506973A JP2011506973A (ja) 2011-03-03
JP2011506973A5 JP2011506973A5 (enExample) 2012-01-26
JP4940438B2 true JP4940438B2 (ja) 2012-05-30

Family

ID=40753794

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010538187A Active JP4940438B2 (ja) 2007-12-14 2008-12-12 疎水性薬物検出法
JP2012021160A Active JP5571108B2 (ja) 2007-12-14 2012-02-02 疎水性薬物検出法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012021160A Active JP5571108B2 (ja) 2007-12-14 2012-02-02 疎水性薬物検出法

Country Status (5)

Country Link
US (3) US7910378B2 (enExample)
EP (1) EP2217926B1 (enExample)
JP (2) JP4940438B2 (enExample)
ES (1) ES2605247T3 (enExample)
WO (1) WO2009079374A1 (enExample)

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US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
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US9121859B2 (en) * 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
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JP7143678B2 (ja) * 2018-08-24 2022-09-29 東ソー株式会社 標的細胞を検出する方法
ES2992864T3 (en) * 2018-11-02 2024-12-18 Siemens Healthcare Diagnostics Inc Binding competitors for use in macrophilin-binding pharmaceutical assays and methods of use thereof
CN114008457A (zh) * 2019-06-28 2022-02-01 美国西门子医学诊断股份有限公司 使用颗粒增强凝集检测的夹心免疫测定试剂及其生产和使用方法
US20210048436A1 (en) 2019-08-15 2021-02-18 Psychemedics Corporation Homogeneous enzyme immunoassay for keratinized structures
CN114964939B (zh) * 2021-12-20 2024-09-13 上海云泽生物科技有限公司 一种药物-蛋白解离组合物、含其的环孢霉素检测试剂盒及应用
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Also Published As

Publication number Publication date
US8334104B2 (en) 2012-12-18
US20090155929A1 (en) 2009-06-18
WO2009079374A1 (en) 2009-06-25
EP2217926A4 (en) 2011-04-06
JP2012112971A (ja) 2012-06-14
JP5571108B2 (ja) 2014-08-13
US20110136136A1 (en) 2011-06-09
US7910378B2 (en) 2011-03-22
JP2011506973A (ja) 2011-03-03
US20120064546A1 (en) 2012-03-15
ES2605247T3 (es) 2017-03-13
EP2217926B1 (en) 2016-10-05
US8071317B2 (en) 2011-12-06
EP2217926A1 (en) 2010-08-18

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