JP4931181B2 - １８ｆ標識フルオロベンゼン環を有する放射性リガンドの合成法 - Google Patents

１８ｆ標識フルオロベンゼン環を有する放射性リガンドの合成法 Download PDF

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Publication number
JP4931181B2
JP4931181B2 JP2006021967A JP2006021967A JP4931181B2 JP 4931181 B2 JP4931181 B2 JP 4931181B2 JP 2006021967 A JP2006021967 A JP 2006021967A JP 2006021967 A JP2006021967 A JP 2006021967A JP 4931181 B2 JP4931181 B2 JP 4931181B2
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JP
Japan
Prior art keywords
group
general formula
compound
synthesizing
radioligand
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Expired - Fee Related
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JP2006021967A
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English (en)
Japanese (ja)
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JP2007204383A (ja
JP2007204383A5 (enExample
Inventor
和年 鈴木
明栄 張
勝志 熊田
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National Institutes For Quantum Science and Technology
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National Institutes For Quantum Science and Technology
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Publication date
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Priority to JP2006021967A priority Critical patent/JP4931181B2/ja
Priority to US12/161,974 priority patent/US8067648B2/en
Priority to PCT/JP2006/323805 priority patent/WO2007088670A1/ja
Publication of JP2007204383A publication Critical patent/JP2007204383A/ja
Publication of JP2007204383A5 publication Critical patent/JP2007204383A5/ja
Application granted granted Critical
Publication of JP4931181B2 publication Critical patent/JP4931181B2/ja
Expired - Fee Related legal-status Critical Current
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/19—Halogen containing
    • Y10T436/196666—Carbon containing compound [e.g., vinylchloride, etc.]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2006021967A 2006-01-31 2006-01-31 １８ｆ標識フルオロベンゼン環を有する放射性リガンドの合成法 Expired - Fee Related JP4931181B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2006021967A JP4931181B2 (ja) 2006-01-31 2006-01-31 １８ｆ標識フルオロベンゼン環を有する放射性リガンドの合成法
US12/161,974 US8067648B2 (en) 2006-01-31 2006-11-29 Method for synthesizing radioactive ligand having 18F-labeled fluorobenzene ring
PCT/JP2006/323805 WO2007088670A1 (ja) 2006-01-31 2006-11-29 １８ｆ標識フルオロベンゼン環を有する放射性リガンドの合成法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006021967A JP4931181B2 (ja) 2006-01-31 2006-01-31 １８ｆ標識フルオロベンゼン環を有する放射性リガンドの合成法

Publications (3)

Publication Number Publication Date
JP2007204383A JP2007204383A (ja) 2007-08-16
JP2007204383A5 JP2007204383A5 (enExample) 2008-11-20
JP4931181B2 true JP4931181B2 (ja) 2012-05-16

Family

ID=38327254

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006021967A Expired - Fee Related JP4931181B2 (ja) 2006-01-31 2006-01-31 １８ｆ標識フルオロベンゼン環を有する放射性リガンドの合成法

Country Status (3)

Country Link
US (1) US8067648B2 (enExample)
JP (1) JP4931181B2 (enExample)
WO (1) WO2007088670A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8415510B2 (en) * 2008-02-28 2013-04-09 Ge Healthcare Limited Synthesis of a PEG-6 moiety from commercial low-cost chemicals
JP2009298725A (ja) * 2008-06-12 2009-12-24 Natl Inst Of Radiological Sciences 蛍光標識フェニルオキシアニリン誘導体及び蛍光標識プローブ
WO2010048170A2 (en) * 2008-10-21 2010-04-29 Board Of Regents Of The University Of Nebraska Fluorination of aromatic ring systems
GB201011408D0 (en) * 2010-07-06 2010-08-18 Isis Innovation Fluorine radiolabelling process
KR101441406B1 (ko) * 2011-05-25 2014-11-04 주식회사 바이오이미징코리아 디아릴이오도늄 염 전구체를 이용한 플로오린-18이 표지된 플루마제닐의 제조 방법
CN103841017B (zh) 2012-11-22 2017-07-14 华为技术有限公司 环网保护中标签自动分配的方法及设备
KR102137214B1 (ko) 2013-12-17 2020-07-23 스텔라파머 가부시키가이샤 2-플루오로-4-보로노-l-페닐알라닌의 제조 방법 및 2-플루오로-4-보로노-l-페닐알라닌의 전구체

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513137A (en) * 1981-04-09 1985-04-23 The University Of Akron Iodonium salts
US5073643A (en) * 1990-08-30 1991-12-17 Polyset Corporation High yield synthesis of hydroxyl-containing cationic photoinitiators
US7049266B2 (en) * 2003-03-31 2006-05-23 Indian Institute Of Chemical Technology Layered double hydroxides supported nanopalladium catalysts for Heck-, Suzuki, Sonogashira-, and Stille type coupling reactions of haloarenes

Also Published As

Publication number Publication date
US20090069592A1 (en) 2009-03-12
JP2007204383A (ja) 2007-08-16
US8067648B2 (en) 2011-11-29
WO2007088670A1 (ja) 2007-08-09

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