JP4917201B2 - 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。 - Google Patents

臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。 Download PDF

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JP4917201B2
JP4917201B2 JP2000368287A JP2000368287A JP4917201B2 JP 4917201 B2 JP4917201 B2 JP 4917201B2 JP 2000368287 A JP2000368287 A JP 2000368287A JP 2000368287 A JP2000368287 A JP 2000368287A JP 4917201 B2 JP4917201 B2 JP 4917201B2
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cord blood
umbilical cord
transplantation
engraftment
cells
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JP2002171966A (ja
JP2002171966A5 (enExample
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暉彬 関根
仁也 伊藤
則夫 清水
憲三 馬場
智宏 山口
保幸 黒岩
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Lymphotec Inc
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Lymphotec Inc
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Priority to JP2000368287A priority Critical patent/JP4917201B2/ja
Priority to EP01310091A priority patent/EP1211311A3/en
Priority to CN01140404A priority patent/CN1363681A/zh
Priority to US10/003,539 priority patent/US6692958B2/en
Publication of JP2002171966A publication Critical patent/JP2002171966A/ja
Publication of JP2002171966A5 publication Critical patent/JP2002171966A5/ja
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50Cell markers; Cell surface determinants
    • C12N2501/515CD3, T-cell receptor complex

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
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  • Biotechnology (AREA)
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  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000368287A 2000-12-04 2000-12-04 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。 Expired - Fee Related JP4917201B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000368287A JP4917201B2 (ja) 2000-12-04 2000-12-04 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。
EP01310091A EP1211311A3 (en) 2000-12-04 2001-12-03 Cord blood-derived activated lymphocytes and preparations containing said lymphocytes
CN01140404A CN1363681A (zh) 2000-12-04 2001-12-04 源于脐带血的活化淋巴细胞、含有所述淋巴细胞作为主要成分的制剂和制备所述制剂的方法与成套器具
US10/003,539 US6692958B2 (en) 2000-12-04 2001-12-04 Cord blood-derived activated lymphocytes, preparations containing said lymphocytes as main ingredient and method and kit for producing said preparations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000368287A JP4917201B2 (ja) 2000-12-04 2000-12-04 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。

Publications (3)

Publication Number Publication Date
JP2002171966A JP2002171966A (ja) 2002-06-18
JP2002171966A5 JP2002171966A5 (enExample) 2008-01-17
JP4917201B2 true JP4917201B2 (ja) 2012-04-18

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Application Number Title Priority Date Filing Date
JP2000368287A Expired - Fee Related JP4917201B2 (ja) 2000-12-04 2000-12-04 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。

Country Status (4)

Country Link
US (1) US6692958B2 (enExample)
EP (1) EP1211311A3 (enExample)
JP (1) JP4917201B2 (enExample)
CN (1) CN1363681A (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572631B2 (en) 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
JP4562353B2 (ja) * 2002-04-08 2010-10-13 株式会社リンフォテック Hla一致他人由来活性化リンパ球を含有してなる腫瘍・感染症および自己免疫疾患の予防・治療用製剤
US20070025961A1 (en) 2003-06-03 2007-02-01 Kenzo Bamba Composition for stabilizing survival of transplanted hematopoietic stem cell, kit for obtaining the composition, method of stabilizing survival of transplanted hematopoietic stem cell, human monoclonal antibody or human polyclonal antibody and method of producing the same, gene encoding human monoclonal antibody and transf
WO2005090977A1 (en) 2004-03-12 2005-09-29 Exelixis, Inc C20orf23 as modifier of the igfr pathway and methods of use
US20080267972A1 (en) * 2005-02-10 2008-10-30 Invitrogen Corporation Donor Lymphocyte Infusion of T Cells For the Treatment of Cancer
JP2007055906A (ja) * 2005-08-22 2007-03-08 Lymphotec:Kk 腫瘍犬の治療法、その治療用製剤、腫瘍犬治療用細胞の凍結保存方法
RU2462511C2 (ru) * 2006-08-01 2012-09-27 Ариджен Фармасьютикалз, Инк. Способ пролиферации клеток lak
JP5596007B2 (ja) * 2011-12-09 2014-09-24 保幸 黒岩 細胞培養方法および培養装置
JP6142142B2 (ja) * 2012-04-10 2017-06-07 株式会社リンフォテック メモリーt細胞を主成分とするリンパ球細胞群の製造方法
CN113952475B (zh) * 2021-09-27 2025-03-11 中国人民解放军陆军军医大学 淋巴细胞和介导crispr系统的纳米复合物联合在制备治疗宫颈癌药物中的应用
CN114438027A (zh) * 2022-02-28 2022-05-06 浙江卫未生物医药科技有限公司 一种脐带血淋巴细胞制剂的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1001034B (el) * 1989-07-21 1993-03-31 Ortho Pharma Corp Μεθοδος διεγερσης του πολλαπλασιασμου λεμφοκυτταρων περιφερειακου αιματος.
IL112969A (en) * 1994-03-17 2001-05-20 Baxter Int Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator
US5773224A (en) * 1996-02-12 1998-06-30 Grandics; Peter Immunoselection system for cell elution
DE69738997D1 (de) * 1996-07-15 2008-10-30 Lymphotec Inc Mittel zur heilung bzw. vorbeugung viraler infektionen, verfahren zu deren herstellung sowie verfahren zur vorbeugung bzw. heilung viraler infektionen
JP4389039B2 (ja) * 1998-04-09 2009-12-24 株式会社リンフォテック アロジェニックな活性化cd4陽性細胞を主成分とする医薬組成物、およびその製造方法、ならびに該医薬組成物調製用キット

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Publication number Publication date
JP2002171966A (ja) 2002-06-18
EP1211311A3 (en) 2003-11-05
CN1363681A (zh) 2002-08-14
EP1211311A2 (en) 2002-06-05
US20020086063A1 (en) 2002-07-04
US6692958B2 (en) 2004-02-17

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