JP4889642B2 - 粒子の処理方法 - Google Patents

粒子の処理方法 Download PDF

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Publication number
JP4889642B2
JP4889642B2 JP2007527430A JP2007527430A JP4889642B2 JP 4889642 B2 JP4889642 B2 JP 4889642B2 JP 2007527430 A JP2007527430 A JP 2007527430A JP 2007527430 A JP2007527430 A JP 2007527430A JP 4889642 B2 JP4889642 B2 JP 4889642B2
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Japan
Prior art keywords
particles
sample
elongated
liquid
particle
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Expired - Fee Related
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JP2007527430A
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English (en)
Japanese (ja)
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JP2007538259A (ja
JP2007538259A5 (enExample
Inventor
デビッド， ジェイ． レークストロー，
フィリップ， エイチ． ポール，
パトリック， ピー． レオン，
Original Assignee
エービー サイエックス エルエルシー
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Publication of JP2007538259A5 publication Critical patent/JP2007538259A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497—Particle shape
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00564—Handling or washing solid phase elements, e.g. beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2007527430A 2004-05-19 2005-05-18 粒子の処理方法 Expired - Fee Related JP4889642B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/849,715 US7175810B2 (en) 2002-11-15 2004-05-19 Processing of particles
US10/849,715 2004-05-19
PCT/US2005/017503 WO2005116642A2 (en) 2004-05-19 2005-05-18 Processing of particles

Publications (3)

Publication Number Publication Date
JP2007538259A JP2007538259A (ja) 2007-12-27
JP2007538259A5 JP2007538259A5 (enExample) 2008-09-11
JP4889642B2 true JP4889642B2 (ja) 2012-03-07

Family

ID=35451506

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007527430A Expired - Fee Related JP4889642B2 (ja) 2004-05-19 2005-05-18 粒子の処理方法

Country Status (4)

Country Link
US (1) US7175810B2 (enExample)
EP (1) EP1766366B1 (enExample)
JP (1) JP4889642B2 (enExample)
WO (1) WO2005116642A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124032B2 (en) * 2004-07-16 2012-02-28 Simon Fraser University Microfluidic device and method of using same
US20070037174A1 (en) * 2005-08-12 2007-02-15 Rampal Jang B Chemiluminescent generated fluorescent labeling
EP2203735A4 (en) * 2007-10-29 2012-03-21 Ca Nat Research Council METHOD AND DEVICE FOR DETECTING PARTICULARLY BONDED FLUOROPHORS IMPEDED BY PARTICULAR CASES
US8815177B2 (en) 2008-01-24 2014-08-26 Sandia Corporation Methods and devices for immobilization of single particles in a virtual channel in a hydrodynamic trap
US9245169B2 (en) * 2012-06-15 2016-01-26 Luminex Corporation Apparatus, system, and method for image normalization using a Gaussian residual of fit selection criteria
US20150362421A1 (en) * 2012-06-22 2015-12-17 Malvern Instruments Limited Particle characterization
US10509976B2 (en) 2012-06-22 2019-12-17 Malvern Panalytical Limited Heterogeneous fluid sample characterization
US9416777B2 (en) 2014-09-26 2016-08-16 Becton, Dickinson And Company Control circuits for electrochemical pump with E-valves
JP7074194B2 (ja) * 2018-07-31 2022-05-24 日本電気株式会社 情報処理装置、制御方法、及びプログラム

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA662714A (en) 1958-11-28 1963-05-07 Union Carbide Corporation Electro-osmotic cell
GB1122586A (en) 1964-09-02 1968-08-07 Mack Gordon Electro-hydraulic transducer
US3923426A (en) 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
WO1998053300A2 (en) * 1997-05-23 1998-11-26 Lynx Therapeutics, Inc. System and apparaus for sequential processing of analytes
US6277257B1 (en) 1997-06-25 2001-08-21 Sandia Corporation Electrokinetic high pressure hydraulic system
JP4209589B2 (ja) * 1997-12-24 2009-01-14 シーフィード 一体型流体操作カートリッジ
EP1115424A1 (de) 1998-08-28 2001-07-18 Febit Ferrarius Biotechnology GmbH Verfahren und messeinrichtung zur bestimmung einer vielzahl von analyten in einer probe
US6086243A (en) 1998-10-01 2000-07-11 Sandia Corporation Electrokinetic micro-fluid mixer
EP2177627B1 (en) * 1999-02-23 2012-05-02 Caliper Life Sciences, Inc. Manipulation of microparticles in microfluidic systems
CA2290731A1 (en) * 1999-11-26 2001-05-26 D. Jed Harrison Apparatus and method for trapping bead based reagents within microfluidic analysis system
SE0001768D0 (sv) 2000-05-12 2000-05-12 Helen Andersson Mikrofluidisk flödescell för manipulering av partiklar
WO2002023180A1 (en) * 2000-09-18 2002-03-21 Hitachi, Ltd. Extractor and chemical analyzer
JP3778041B2 (ja) * 2000-12-08 2006-05-24 コニカミノルタホールディングス株式会社 粒子分離機構及び粒子分離装置
JP3695431B2 (ja) * 2001-08-03 2005-09-14 日本電気株式会社 分離装置および分離装置の製造方法
US20030091475A1 (en) 2001-09-26 2003-05-15 Micralyne Inc. Bead trapping device
EP1499706A4 (en) 2002-04-01 2010-11-03 Fluidigm Corp MICROFLUIDIC PARTICLE ANALYSIS SYSTEMS
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
US7220592B2 (en) * 2002-11-15 2007-05-22 Eksigent Technologies, Llc Particulate processing system
DE10313201A1 (de) * 2003-03-21 2004-10-07 Steag Microparts Gmbh Mikrostrukturierte Trennvorrichtung und mikrofluidisches Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Flüssigkeit, die Partikel enthält

Also Published As

Publication number Publication date
WO2005116642A3 (en) 2006-01-26
US7175810B2 (en) 2007-02-13
JP2007538259A (ja) 2007-12-27
EP1766366A2 (en) 2007-03-28
WO2005116642A2 (en) 2005-12-08
EP1766366A4 (en) 2013-07-10
US20040235181A1 (en) 2004-11-25
EP1766366B1 (en) 2014-12-03

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