JP4806630B2 - 多軸統合を用いて三次元対象物の光学的画像データを取得する方法 - Google Patents

多軸統合を用いて三次元対象物の光学的画像データを取得する方法 Download PDF

Info

Publication number
JP4806630B2
JP4806630B2 JP2006507044A JP2006507044A JP4806630B2 JP 4806630 B2 JP4806630 B2 JP 4806630B2 JP 2006507044 A JP2006507044 A JP 2006507044A JP 2006507044 A JP2006507044 A JP 2006507044A JP 4806630 B2 JP4806630 B2 JP 4806630B2
Authority
JP
Japan
Prior art keywords
image
scan
image data
optical
integration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2006507044A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006520473A (ja
Inventor
スティーブン エー． リース，
カール エス． ブラウン，
ポール シー． グッドウィン，
Original Assignee
アプライド プリシジョン， エルエルシー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アプライド プリシジョン， エルエルシー filed Critical アプライド プリシジョン， エルエルシー
Publication of JP2006520473A publication Critical patent/JP2006520473A/ja
Application granted granted Critical
Publication of JP4806630B2 publication Critical patent/JP4806630B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T1/00—General purpose image data processing
    • G06T1/0007—Image acquisition
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N25/00—Circuitry of solid-state image sensors [SSIS]; Control thereof
    • H04N25/48—Increasing resolution by shifting the sensor relative to the scene
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N25/00—Circuitry of solid-state image sensors [SSIS]; Control thereof
    • H04N25/70—SSIS architectures; Circuits associated therewith
    • H04N25/71—Charge-coupled device [CCD] sensors; Charge-transfer registers specially adapted for CCD sensors
    • H04N25/711—Time delay and integration [TDI] registers; TDI shift registers
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N25/00—Circuitry of solid-state image sensors [SSIS]; Control thereof
    • H04N25/70—SSIS architectures; Circuits associated therewith
    • H04N25/76—Addressed sensors, e.g. MOS or CMOS sensors
    • H04N25/768—Addressed sensors, e.g. MOS or CMOS sensors for time delay and integration [TDI]

Landscapes

  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Physics & Mathematics (AREA)
  • Signal Processing (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Microscoopes, Condenser (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Image Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2006507044A 2003-03-13 2004-03-12 多軸統合を用いて三次元対象物の光学的画像データを取得する方法 Expired - Fee Related JP4806630B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/389,269 2003-03-13
US10/389,269 US7283253B2 (en) 2002-03-13 2003-03-13 Multi-axis integration system and method
PCT/US2004/007323 WO2004083832A1 (en) 2003-03-13 2004-03-12 Multi-axis integration system and method

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010269818A Division JP2011085594A (ja) 2003-03-13 2010-12-02 多軸統合システムおよび方法

Publications (2)

Publication Number Publication Date
JP2006520473A JP2006520473A (ja) 2006-09-07
JP4806630B2 true JP4806630B2 (ja) 2011-11-02

Family

ID=33029658

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006507044A Expired - Fee Related JP4806630B2 (ja) 2003-03-13 2004-03-12 多軸統合を用いて三次元対象物の光学的画像データを取得する方法
JP2010269818A Pending JP2011085594A (ja) 2003-03-13 2010-12-02 多軸統合システムおよび方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010269818A Pending JP2011085594A (ja) 2003-03-13 2010-12-02 多軸統合システムおよび方法

Country Status (4)

Country Link
US (3) US7283253B2 (enExample)
EP (1) EP1606609A1 (enExample)
JP (2) JP4806630B2 (enExample)
WO (1) WO2004083832A1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7668362B2 (en) 2000-05-03 2010-02-23 Aperio Technologies, Inc. System and method for assessing virtual slide image quality
US7907765B2 (en) 2001-03-28 2011-03-15 University Of Washington Focal plane tracking for optical microtomography
US20060023219A1 (en) * 2001-03-28 2006-02-02 Meyer Michael G Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification
US7811825B2 (en) * 2002-04-19 2010-10-12 University Of Washington System and method for processing specimens and images for optical tomography
US7738945B2 (en) * 2002-04-19 2010-06-15 University Of Washington Method and apparatus for pseudo-projection formation for optical tomography
US20050085708A1 (en) * 2002-04-19 2005-04-21 University Of Washington System and method for preparation of cells for 3D image acquisition
US7260253B2 (en) * 2002-04-19 2007-08-21 Visiongate, Inc. Method for correction of relative object-detector motion between successive views
US7408176B2 (en) 2003-06-19 2008-08-05 Applied Precision, Llc System and method employing photokinetic techniques in cell biology imaging applications
JP3803673B2 (ja) * 2004-02-02 2006-08-02 オリンパス株式会社 測定方法及び測定装置
EP1756750A4 (en) * 2004-05-27 2010-10-20 Aperio Technologies Inc SYSTEMS AND METHOD FOR PRODUCING AND LOOKING AT THREE-DIMENSIONAL VIRTUAL FOILS
US20060018013A1 (en) * 2004-07-07 2006-01-26 Yoshimasa Suzuki Microscope imaging apparatus and biological-specimen examination system
US20060096358A1 (en) * 2004-10-28 2006-05-11 University Of Washington Optical projection tomography microscope
JP4634868B2 (ja) * 2005-06-03 2011-02-16 株式会社ミツトヨ 画像測定方法及びシステム
US8164622B2 (en) 2005-07-01 2012-04-24 Aperio Technologies, Inc. System and method for single optical axis multi-detector microscope slide scanner
JP2008058133A (ja) * 2006-08-31 2008-03-13 Tohoku Univ 長尺工具エッジの曲率半径の計測装置および長尺工具エッジの曲率半径の計測方法
SE530789C2 (sv) * 2007-01-17 2008-09-09 Hemocue Ab Apparat och metod för positionsbestämning av objekt vilka inryms i ett prov
WO2008088249A1 (en) * 2007-01-17 2008-07-24 Hemocue Ab Apparatus for determining positions of objects contained in a sample
US8717426B2 (en) * 2007-05-17 2014-05-06 M-I Llc Liquid and solids analysis of drilling fluids using fractionation and imaging
US7835561B2 (en) 2007-05-18 2010-11-16 Visiongate, Inc. Method for image processing and reconstruction of images for optical tomography
US7787112B2 (en) 2007-10-22 2010-08-31 Visiongate, Inc. Depth of field extension for optical tomography
US8143600B2 (en) * 2008-02-18 2012-03-27 Visiongate, Inc. 3D imaging of live cells with ultraviolet radiation
US8743195B2 (en) * 2008-10-24 2014-06-03 Leica Biosystems Imaging, Inc. Whole slide fluorescence scanner
US8254023B2 (en) 2009-02-23 2012-08-28 Visiongate, Inc. Optical tomography system with high-speed scanner
US8717417B2 (en) 2009-04-16 2014-05-06 Primesense Ltd. Three-dimensional mapping and imaging
US9030528B2 (en) * 2011-04-04 2015-05-12 Apple Inc. Multi-zone imaging sensor and lens array
US9742993B2 (en) 2012-02-16 2017-08-22 University Of Washington Through Its Center For Commercialization Extended depth of focus for high-resolution optical image scanning
US9404869B2 (en) * 2012-10-09 2016-08-02 Howard Hughes Medical Institute Multiview light-sheet microscopy
JP2014164004A (ja) * 2013-02-22 2014-09-08 Hitachi High-Technologies Corp 蛍光顕微鏡
CN103398669A (zh) * 2013-07-30 2013-11-20 深圳市大族激光科技股份有限公司 一种用于测量自由曲面的多轴联动视觉检测方法和设备
WO2016022359A1 (en) * 2014-08-06 2016-02-11 Cellomics, Inc. Image-based laser autofocus system
EP3213139B1 (en) * 2014-10-29 2021-11-24 Molecular Devices, LLC Apparatus and method for generating in-focus images using parallel imaging in a microscopy system
US10690897B2 (en) * 2015-04-20 2020-06-23 Canon Kabushiki Kaisha Laser scanning microscope apparatus
US11069054B2 (en) 2015-12-30 2021-07-20 Visiongate, Inc. System and method for automated detection and monitoring of dysplasia and administration of immunotherapy and chemotherapy
US10623627B2 (en) * 2016-02-22 2020-04-14 Koninklijke Philips N.V. System for generating a synthetic 2D image with an enhanced depth of field of a biological sample
US20210149170A1 (en) * 2019-11-15 2021-05-20 Scopio Labs Ltd. Method and apparatus for z-stack acquisition for microscopic slide scanner
KR102799293B1 (ko) * 2021-11-18 2025-04-29 한국광기술원 Z축 스캐닝을 포함하는 전체 슬라이드 이미지 생성 장치 및 방법

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01309478A (ja) * 1988-02-23 1989-12-13 Olympus Optical Co Ltd 画像入出力装置
JPH06259533A (ja) * 1993-03-05 1994-09-16 Olympus Optical Co Ltd 光学像再構成装置
JPH08241396A (ja) * 1995-03-07 1996-09-17 Olympus Optical Co Ltd 光学像再構成装置
JPH09149895A (ja) * 1995-11-30 1997-06-10 Hitachi Medical Corp Ｘ線画像作成方法およびその装置
JPH09298682A (ja) * 1996-04-30 1997-11-18 Olympus Optical Co Ltd 焦点深度伸長装置
JP2002535717A (ja) * 1999-01-22 2002-10-22 キュー・スリー・ディ・エム・リミテッド・ライアビリティ・カンパニー 高解像度顕微鏡法における連続画像収集に対する自動オン・ザ・フライ焦点合わせ
WO2003014400A1 (en) * 2001-08-08 2003-02-20 Applied Precision, Llc Time-delay integration imaging of biological specimens

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383327A (en) * 1980-12-01 1983-05-10 University Of Utah Radiographic systems employing multi-linear arrays of electronic radiation detectors
GB8317407D0 (en) * 1983-06-27 1983-07-27 Rca Corp Image transform techniques
US4584704A (en) * 1984-03-01 1986-04-22 Bran Ferren Spatial imaging system
US5141609A (en) * 1990-11-16 1992-08-25 The Trustees Of The Leland Stanford Junior University Method and device employing time-delayed integration for detecting sample components after separation
US5201899A (en) * 1991-06-28 1993-04-13 A-Dec, Inc. Control system for dental handpieces
US5231443A (en) * 1991-12-16 1993-07-27 The Research Foundation Of State University Of New York Automatic ranging and automatic focusing
JP3568286B2 (ja) * 1995-08-29 2004-09-22 オリンパス株式会社 共焦点走査型光学顕微鏡及びこの顕微鏡を使用した測定方法
SE9601229D0 (sv) * 1996-03-07 1996-03-29 B Ulf Skoglund Apparatus and method for providing reconstruction
US5889582A (en) * 1997-03-10 1999-03-30 Virtek Vision Corporation Image-directed active range finding system
US6603103B1 (en) * 1998-07-08 2003-08-05 Ppt Vision, Inc. Circuit for machine-vision system
US6081577A (en) * 1998-07-24 2000-06-27 Wake Forest University Method and system for creating task-dependent three-dimensional images
US6320979B1 (en) * 1998-10-06 2001-11-20 Canon Kabushiki Kaisha Depth of field enhancement
US6201899B1 (en) * 1998-10-09 2001-03-13 Sarnoff Corporation Method and apparatus for extended depth of field imaging
US20020001089A1 (en) * 2000-04-18 2002-01-03 Price Jeffrey H. Multiparallel three dimensional optical microscopy system
US6711283B1 (en) * 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US6856390B2 (en) * 2001-07-25 2005-02-15 Applera Corporation Time-delay integration in electrophoretic detection systems
WO2003079664A2 (en) 2002-03-13 2003-09-25 Applied Precision, Llc Multi-axis integration system and method

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01309478A (ja) * 1988-02-23 1989-12-13 Olympus Optical Co Ltd 画像入出力装置
JPH06259533A (ja) * 1993-03-05 1994-09-16 Olympus Optical Co Ltd 光学像再構成装置
JPH08241396A (ja) * 1995-03-07 1996-09-17 Olympus Optical Co Ltd 光学像再構成装置
JPH09149895A (ja) * 1995-11-30 1997-06-10 Hitachi Medical Corp Ｘ線画像作成方法およびその装置
JPH09298682A (ja) * 1996-04-30 1997-11-18 Olympus Optical Co Ltd 焦点深度伸長装置
JP2002535717A (ja) * 1999-01-22 2002-10-22 キュー・スリー・ディ・エム・リミテッド・ライアビリティ・カンパニー 高解像度顕微鏡法における連続画像収集に対する自動オン・ザ・フライ焦点合わせ
WO2003014400A1 (en) * 2001-08-08 2003-02-20 Applied Precision, Llc Time-delay integration imaging of biological specimens

Also Published As

Publication number Publication date
US20030222197A1 (en) 2003-12-04
US20060039010A1 (en) 2006-02-23
WO2004083832A1 (en) 2004-09-30
EP1606609A1 (en) 2005-12-21
JP2011085594A (ja) 2011-04-28
JP2006520473A (ja) 2006-09-07
US7283253B2 (en) 2007-10-16
US20080245953A1 (en) 2008-10-09

Similar Documents

Publication Publication Date Title
JP4806630B2 (ja) 多軸統合を用いて三次元対象物の光学的画像データを取得する方法
US10944896B2 (en) Single-frame autofocusing using multi-LED illumination
JP7252190B2 (ja) 生物試料の向上された被写界深度の合成２ｄ画像を生成するシステム
US8019136B2 (en) Optical sectioning microscopy
JP6503221B2 (ja) ３次元情報取得装置、及び、３次元情報取得方法
KR102419163B1 (ko) 실시간 오토포커스 포커싱 알고리즘
WO2007067999A2 (en) Extended depth of field imaging for high speed object analysis
JP2002531840A (ja) コンピュータを使用した適応画像形成装置及び方法
KR20140045331A (ko) 현미경 이미징에서의 빠른 오토-포커스
CN102053355A (zh) 用于具有增强景深的成像的系统和方法
CN102053356A (zh) 用于具有增强景深的成像的系统和方法
JP6940696B2 (ja) 二次元および三次元の固定式ｚ走査
CN111164484A (zh) 双程微距图像
JP2020525848A (ja) 異なるサイズのスライド用の調整可能なスライドステージ
JP7119085B2 (ja) 衝撃再走査システム
US20230247276A1 (en) Re-imaging microscopy with micro-camera array
JP2025530978A (ja) 体積画像化のためのコンピュータ顕微鏡法およびシステム
JP2006317261A (ja) 走査型サイトメータの画像処理方法及び装置
WO2003079664A2 (en) Multi-axis integration system and method
CN111279242B (zh) 双处理器图像处理
WO2025165589A1 (en) Fast scanning and image processing in a line scanning system
WO2025166175A1 (en) Systems and methods for image processing and adaptive control in microscope systems
WO2021174200A1 (en) Systems and methods for composing high dimensional microscopy images in subpixel resolution

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070202

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20091002

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091229

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100106

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100112

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100114

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100329

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100602

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100901

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100908

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100929

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20101006

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20101021

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20101028

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101202

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110407

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110623

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110725

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110815

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140819

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140819

Year of fee payment: 3

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140819

Year of fee payment: 3

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140819

Year of fee payment: 3

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: R3D02

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313111

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees