JP4801257B2 - ペプチドターン模倣構造体 - Google Patents

ペプチドターン模倣構造体 Download PDF

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Publication number
JP4801257B2
JP4801257B2 JP2000537895A JP2000537895A JP4801257B2 JP 4801257 B2 JP4801257 B2 JP 4801257B2 JP 2000537895 A JP2000537895 A JP 2000537895A JP 2000537895 A JP2000537895 A JP 2000537895A JP 4801257 B2 JP4801257 B2 JP 4801257B2
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JP
Japan
Prior art keywords
compound
group
mimetic
boc
nmr
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Expired - Lifetime
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JP2000537895A
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English (en)
Japanese (ja)
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JP2002507624A5 (https=
JP2002507624A (ja
Inventor
ヨセフ キャシディ、ピーター
アラン ハント、ピーター
フランシス アレウッド、ポール
エリザベス ラムズデール、トレーシー
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Mimetica Pty Ltd
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Mimetica Pty Ltd
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Application filed by Mimetica Pty Ltd filed Critical Mimetica Pty Ltd
Publication of JP2002507624A publication Critical patent/JP2002507624A/ja
Publication of JP2002507624A5 publication Critical patent/JP2002507624A5/ja
Application granted granted Critical
Publication of JP4801257B2 publication Critical patent/JP4801257B2/ja
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Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2000537895A 1998-03-24 1999-03-24 ペプチドターン模倣構造体 Expired - Lifetime JP4801257B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2548 1998-03-24
AUPP2548A AUPP254898A0 (en) 1998-03-24 1998-03-24 Peptide turn mimetics
AUPP2548 1998-03-24
PCT/AU1999/000207 WO1999048913A1 (en) 1998-03-24 1999-03-24 Peptide turn mimetics

Publications (3)

Publication Number Publication Date
JP2002507624A JP2002507624A (ja) 2002-03-12
JP2002507624A5 JP2002507624A5 (https=) 2006-05-25
JP4801257B2 true JP4801257B2 (ja) 2011-10-26

Family

ID=3806810

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000537895A Expired - Lifetime JP4801257B2 (ja) 1998-03-24 1999-03-24 ペプチドターン模倣構造体

Country Status (8)

Country Link
US (1) US20110040087A1 (https=)
EP (1) EP1064300B1 (https=)
JP (1) JP4801257B2 (https=)
AT (1) ATE424408T1 (https=)
AU (1) AUPP254898A0 (https=)
CA (1) CA2325937C (https=)
DE (1) DE69940500D1 (https=)
WO (1) WO1999048913A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2284459C (en) * 1999-10-04 2012-12-11 Neokimia Inc. Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery
FR2803594B1 (fr) * 2000-01-11 2002-07-19 Centre Nat Rech Scient Oligomeres de mimes contraints non peptidiques de dipeptides ou de tripeptides, et leurs utilisations
US8114844B2 (en) 2006-03-30 2012-02-14 Palatin Technologies, Inc. Linear and cyclic melanocortin receptor-specific peptidomimetics
US7964181B2 (en) 2006-03-30 2011-06-21 Palatin Technologies, Inc. Amino acid surrogates for peptidic constructs
EP2001518B1 (en) * 2006-03-30 2013-07-10 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs
CN102007106B (zh) * 2008-02-29 2014-09-03 麦提卡公司 3-取代的-1，4-二氮杂卓-2-酮黑皮质素-5受体拮抗剂
US8343958B2 (en) 2008-02-29 2013-01-01 Mimetica Pty Ltd 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5-receptor antagonists
US8008291B2 (en) 2008-02-29 2011-08-30 Mimetica Pty Ltd 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5 receptor antagonists
RU2555343C9 (ru) * 2008-02-29 2015-11-27 Миметика Пти Лтд Способы модулирования активности мс5 рецептора и лечение состояний, относящихся к данному рецептору
US8377925B2 (en) 2008-02-29 2013-02-19 Mimetica Pty Ltd Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor
WO2010096853A1 (en) * 2009-02-27 2010-09-02 Mimetica Pty Ltd Methods of modulating the activity of the mc1 receptor and treatment of conditions related to this receptor
WO2010096854A1 (en) * 2009-02-27 2010-09-02 Mimetica Pty Ltd Methods of modulating the activity of the mc3 and/or mc4 receptors and treatment of conditions related to these receptors
JP6801835B2 (ja) * 2015-07-09 2020-12-16 ミメトゲン ファーマシュウティカルズ インコーポレイテッドＭｉｍｅｔｏｇｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． β−ターンペプチド模倣環状塩の液相合成及び結晶化
WO2023119230A1 (en) 2021-12-22 2023-06-29 L'oreal Coagulation pathway and nicotinamide-adenine dinucleotide pathway modulating compositions and methods of their use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013878A2 (en) * 1991-02-07 1992-08-20 Board Of Trustees Of The University Of Illinois Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
US5693325A (en) * 1994-03-15 1997-12-02 Molecumetics, Ltd. Peptide vaccines and methods relating thereto
JPH10512570A (ja) * 1995-01-20 1998-12-02 モレキュメティックス リミテッド コンホメーション的に制限された逆ターンライブラリおよびそれらに関連する方法
US5929237A (en) * 1995-10-27 1999-07-27 Molecumetics Ltd. Reverse-turn mimetics and methods relating thereto
US6013458A (en) * 1995-10-27 2000-01-11 Molecumetics, Ltd. Reverse-turn mimetics and methods relating thereto
US20090275727A1 (en) * 1998-03-24 2009-11-05 Mimetica Pty Limited Peptide turn mimetics

Also Published As

Publication number Publication date
CA2325937A1 (en) 1999-09-30
ATE424408T1 (de) 2009-03-15
EP1064300A1 (en) 2001-01-03
EP1064300A4 (en) 2006-03-29
AUPP254898A0 (en) 1998-04-23
US20110040087A1 (en) 2011-02-17
WO1999048913A1 (en) 1999-09-30
DE69940500D1 (de) 2009-04-16
EP1064300B1 (en) 2009-03-04
CA2325937C (en) 2011-02-15
JP2002507624A (ja) 2002-03-12

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