DE69940500D1 - Peptidschleifenmimetika - Google Patents

Peptidschleifenmimetika

Info

Publication number
DE69940500D1
DE69940500D1 DE69940500T DE69940500T DE69940500D1 DE 69940500 D1 DE69940500 D1 DE 69940500D1 DE 69940500 T DE69940500 T DE 69940500T DE 69940500 T DE69940500 T DE 69940500T DE 69940500 D1 DE69940500 D1 DE 69940500D1
Authority
DE
Germany
Prior art keywords
iii
sidechain
mimetics
peptide
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69940500T
Other languages
German (de)
English (en)
Inventor
Peter Joseph Cassidy
Peter Alan Hunt
Paul Francis Alewood
Tracie Elizabeth Ramsdale
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mimetica Pty Ltd
Original Assignee
Mimetica Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mimetica Pty Ltd filed Critical Mimetica Pty Ltd
Application granted granted Critical
Publication of DE69940500D1 publication Critical patent/DE69940500D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69940500T 1998-03-24 1999-03-24 Peptidschleifenmimetika Expired - Lifetime DE69940500D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPP2548A AUPP254898A0 (en) 1998-03-24 1998-03-24 Peptide turn mimetics
PCT/AU1999/000207 WO1999048913A1 (en) 1998-03-24 1999-03-24 Peptide turn mimetics

Publications (1)

Publication Number Publication Date
DE69940500D1 true DE69940500D1 (de) 2009-04-16

Family

ID=3806810

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69940500T Expired - Lifetime DE69940500D1 (de) 1998-03-24 1999-03-24 Peptidschleifenmimetika

Country Status (8)

Country Link
US (1) US20110040087A1 (https=)
EP (1) EP1064300B1 (https=)
JP (1) JP4801257B2 (https=)
AT (1) ATE424408T1 (https=)
AU (1) AUPP254898A0 (https=)
CA (1) CA2325937C (https=)
DE (1) DE69940500D1 (https=)
WO (1) WO1999048913A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2284459C (en) * 1999-10-04 2012-12-11 Neokimia Inc. Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery
FR2803594B1 (fr) * 2000-01-11 2002-07-19 Centre Nat Rech Scient Oligomeres de mimes contraints non peptidiques de dipeptides ou de tripeptides, et leurs utilisations
US8114844B2 (en) 2006-03-30 2012-02-14 Palatin Technologies, Inc. Linear and cyclic melanocortin receptor-specific peptidomimetics
US7964181B2 (en) 2006-03-30 2011-06-21 Palatin Technologies, Inc. Amino acid surrogates for peptidic constructs
EP2001518B1 (en) * 2006-03-30 2013-07-10 Palatin Technologies, Inc. Cyclic natriuretic peptide constructs
CN102007106B (zh) * 2008-02-29 2014-09-03 麦提卡公司 3-取代的-1，4-二氮杂卓-2-酮黑皮质素-5受体拮抗剂
US8343958B2 (en) 2008-02-29 2013-01-01 Mimetica Pty Ltd 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5-receptor antagonists
US8008291B2 (en) 2008-02-29 2011-08-30 Mimetica Pty Ltd 3-aminoalkyl-1,4-diazepan-2-one melanocortin-5 receptor antagonists
RU2555343C9 (ru) * 2008-02-29 2015-11-27 Миметика Пти Лтд Способы модулирования активности мс5 рецептора и лечение состояний, относящихся к данному рецептору
US8377925B2 (en) 2008-02-29 2013-02-19 Mimetica Pty Ltd Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor
WO2010096853A1 (en) * 2009-02-27 2010-09-02 Mimetica Pty Ltd Methods of modulating the activity of the mc1 receptor and treatment of conditions related to this receptor
WO2010096854A1 (en) * 2009-02-27 2010-09-02 Mimetica Pty Ltd Methods of modulating the activity of the mc3 and/or mc4 receptors and treatment of conditions related to these receptors
JP6801835B2 (ja) * 2015-07-09 2020-12-16 ミメトゲン ファーマシュウティカルズ インコーポレイテッドＭｉｍｅｔｏｇｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． β−ターンペプチド模倣環状塩の液相合成及び結晶化
WO2023119230A1 (en) 2021-12-22 2023-06-29 L'oreal Coagulation pathway and nicotinamide-adenine dinucleotide pathway modulating compositions and methods of their use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013878A2 (en) * 1991-02-07 1992-08-20 Board Of Trustees Of The University Of Illinois Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
US5693325A (en) * 1994-03-15 1997-12-02 Molecumetics, Ltd. Peptide vaccines and methods relating thereto
JPH10512570A (ja) * 1995-01-20 1998-12-02 モレキュメティックス リミテッド コンホメーション的に制限された逆ターンライブラリおよびそれらに関連する方法
US5929237A (en) * 1995-10-27 1999-07-27 Molecumetics Ltd. Reverse-turn mimetics and methods relating thereto
US6013458A (en) * 1995-10-27 2000-01-11 Molecumetics, Ltd. Reverse-turn mimetics and methods relating thereto
US20090275727A1 (en) * 1998-03-24 2009-11-05 Mimetica Pty Limited Peptide turn mimetics

Also Published As

Publication number Publication date
CA2325937A1 (en) 1999-09-30
ATE424408T1 (de) 2009-03-15
EP1064300A1 (en) 2001-01-03
EP1064300A4 (en) 2006-03-29
AUPP254898A0 (en) 1998-04-23
US20110040087A1 (en) 2011-02-17
WO1999048913A1 (en) 1999-09-30
JP4801257B2 (ja) 2011-10-26
EP1064300B1 (en) 2009-03-04
CA2325937C (en) 2011-02-15
JP2002507624A (ja) 2002-03-12

Similar Documents

Publication Publication Date Title
DE69940500D1 (de) Peptidschleifenmimetika
NO20034291L (no) 2-aminopropanolderivater
EA200101078A1 (ru) Получение биологически активных молекул
ES2139043T3 (es) Compuestos de azaciclohexapeptidos.
RU95116650A (ru) Гидрат кальпотриола и фармацевтическая композиция
PT934325E (pt) Trisanidridos biciclicos de tetrafosfonato
EP0735819A4 (en) NEW CRYPTOPHYCINE
CA2537373A1 (en) Selective synthesis of cf3-substituted pyrimidines
JO2243B1 (en) Prepare a 6.3-dicyl-6.5-dihydro-4 hydroxy-pyran-2-one compound
BR9610905A (pt) Derivados de sulfamato processo de fabricação de derivados de sulfamato e composições farmacêuticas
JO2249B1 (en) A compound of 6.3-dialkyl-6.5-dihydro-4-hydroxy-biran-2-one
CA2301175A1 (en) Collagen mimics
Magnus et al. Oxidation of L-Proline methyl ester derivatives with the iodosylbenzene/trimethylsilylazide reagent combination
AU3258197A (en) Peptides
Morita et al. Cycloleonuripeptide D, a new proline-rich cyclic decapeptide from Leonurus heterophyllus
Kakizawa et al. Histone H3 peptides incorporating modified lysine residues as lysine-specific demethylase 1 inhibitors
WO1999001551A3 (en) Novel inhibitor of cellular proliferation
ZA978503B (en) Vertebrate smoothened proteins
DE60043228D1 (de) Herstellungsverfahren von 2-cyanopyridinen
SE9800865D0 (sv) New Process
EA200300400A1 (ru) 17α-ФТОРАЛКИЛСТЕРОИДЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ И СОДЕРЖАЩИЕ ЭТИ СОЕДИНЕНИЯ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
ID27440A (id) Proses untuk menyiapkan penengah-penengah
EA200500224A1 (ru) МИКРОБИОЛОГИЧЕСКИЕ СПОСОБЫ ПОЛУЧЕНИЯ 7α-ЗАМЕЩЁННЫХ 11α-ГИДРОКСИСТЕРОИДОВ
ZA983231B (en) Substituted benzyloxyimino compounds.
IT1313624B1 (it) Procedimento per la sintesi del ritonavir

Legal Events

Date Code Title Description
8364 No opposition during term of opposition