JP4782701B2 - 液体クロマトグラフィーのための試料注入システム - Google Patents

液体クロマトグラフィーのための試料注入システム Download PDF

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JP4782701B2
JP4782701B2 JP2006551418A JP2006551418A JP4782701B2 JP 4782701 B2 JP4782701 B2 JP 4782701B2 JP 2006551418 A JP2006551418 A JP 2006551418A JP 2006551418 A JP2006551418 A JP 2006551418A JP 4782701 B2 JP4782701 B2 JP 4782701B2
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Japan
Prior art keywords
fluid
chamber
valve means
outlet
conduit
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JP2006551418A
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English (en)
Japanese (ja)
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JP2007519007A5 (https=
JP2007519007A (ja
Inventor
ゲルハルト，ジエフ・シー
ジヨージエンソン，ジエームズ・ダブリユ
フアドゲン，キース
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ウオーターズ・テクノロジーズ・コーポレイシヨン
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/22—Injection in high pressure liquid systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N2030/382—Flow patterns flow switching in a single column
    • G01N2030/385—Flow patterns flow switching in a single column by switching valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/36—Control of physical parameters of the fluid carrier in high pressure liquid systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

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  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Fluid Mechanics (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)
JP2006551418A 2004-01-23 2005-01-18 液体クロマトグラフィーのための試料注入システム Expired - Fee Related JP4782701B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53868304P 2004-01-23 2004-01-23
US60/538,683 2004-01-23
PCT/US2005/002401 WO2005071396A1 (en) 2004-01-23 2005-01-18 A sample injector system for liquid chromatography

Publications (3)

Publication Number Publication Date
JP2007519007A JP2007519007A (ja) 2007-07-12
JP2007519007A5 JP2007519007A5 (https=) 2008-02-21
JP4782701B2 true JP4782701B2 (ja) 2011-09-28

Family

ID=34807210

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006551418A Expired - Fee Related JP4782701B2 (ja) 2004-01-23 2005-01-18 液体クロマトグラフィーのための試料注入システム

Country Status (5)

Country Link
US (1) US8173070B2 (https=)
JP (1) JP4782701B2 (https=)
DE (1) DE112005000128B4 (https=)
GB (2) GB2426216B (https=)
WO (1) WO2005071396A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008006266B4 (de) 2008-01-25 2011-06-09 Dionex Softron Gmbh Probengeber für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie
US9151734B2 (en) * 2009-03-05 2015-10-06 Idex Health & Science Llc Connection assembly for ultra high pressure liquid chromatography
US20100224543A1 (en) 2009-03-05 2010-09-09 Ellis Scott J Connection assembly for ultra high pressure liquid chromatography
WO2010139359A1 (en) 2009-06-03 2010-12-09 Agilent Technologies, Inc. Sample injector with metering device balancing pressure differences in an intermediate valve state
US20120227470A1 (en) * 2009-06-26 2012-09-13 Waters Technologies Corporation Chromatography Apparatus Having An Integrated Core
US8541493B2 (en) * 2010-02-19 2013-09-24 Arch Chemicals, Inc. Synthesis of zinc acrylate copolymer from acid functional copolymer, zinc pyrithione, and copper compound
SG183177A1 (en) * 2010-02-26 2012-09-27 Perkinelmer Health Sci Inc Jet assembly for use in detectors and other devices
EP2539703B1 (en) * 2010-02-26 2021-01-20 PerkinElmer Health Sciences, Inc. Fluid chromatography injectors and injector inserts
US8569070B2 (en) 2010-07-16 2013-10-29 Idex Health & Science Llc Connection assembly for ultra high pressure liquid chromatography
JP5868977B2 (ja) 2010-08-10 2016-02-24 アイデックス ヘルス アンド サイエンス エルエルシー 液体クロマトグラフィシステム用の生体適合性管
US9188569B2 (en) 2011-03-01 2015-11-17 Idex Health & Science Llc High pressure fitting with self-releasing ferrule
US8931808B2 (en) 2011-03-01 2015-01-13 Idex Health & Science Llc High pressure fitting with self-releasing ferrule
EP2626697B1 (en) 2012-02-07 2018-10-31 King Saud University Liquid chromatography device
US9791080B2 (en) 2012-03-12 2017-10-17 Idex Health & Science Llc Microfluidic interconnect
WO2014074499A1 (en) 2012-11-06 2014-05-15 Idex Health & Science Llc Torque limiting tool and methods
TWI579553B (zh) 2013-11-24 2017-04-21 中央研究院 以紫外光－可見光檢測之高效能液相層析設備及方法
US10422452B2 (en) 2014-04-16 2019-09-24 IDEX Health & Sciences LLC High pressure fluidic connection assemblies
WO2015179430A1 (en) 2014-05-20 2015-11-26 Idex Health & Science Llc Frits for chromatography
JP6767973B2 (ja) 2014-10-23 2020-10-14 アイデックス ヘルス アンド サイエンス エルエルシー 面シール流体接続システム
US10012620B1 (en) 2015-04-07 2018-07-03 Sielc Technologies Corporation Chromatography sample introduction device
US10371672B1 (en) 2015-04-15 2019-08-06 Yury Zelechonok Integrated chromatography column injector detector device
DE202016100451U1 (de) 2015-06-25 2016-02-16 Dionex Softron Gmbh Probengeber für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie
US10520477B2 (en) 2016-12-09 2019-12-31 Idex Health & Science Llc High pressure valve with multi-piece stator assembly
US11054054B2 (en) 2016-12-09 2021-07-06 Idex Health & Science Llc High pressure valve with multi-piece stator assembly
US10384151B2 (en) 2016-12-09 2019-08-20 Idex Health & Science Llc High pressure valve with two-piece stator assembly
EP3561504B1 (en) 2018-04-25 2023-01-04 Idex Health & Science LLC High pressure valve with multi-piece stator assembly
US11085904B2 (en) 2018-09-28 2021-08-10 Idex Health And Science Llc Column having a compression-limited assembly

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0933502A (ja) * 1995-07-18 1997-02-07 Shimadzu Corp ガスクロマトグラフ装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US328910A (en) 1885-10-20 Corn and cane harvester
US3186234A (en) 1961-09-12 1965-06-01 Beckman Instruments Inc Sampling valve
US3621263A (en) * 1970-04-13 1971-11-16 Warren E Gilson Volumetric fraction supply apparatus
DE3865831D1 (de) 1988-02-11 1991-11-28 Hewlett Packard Gmbh Fluessigproben-injektionseinrichtung.
EP0701688B1 (en) * 1993-06-05 1997-09-03 Glaxo Group Limited Liquid flow management means
DE4447333A1 (de) * 1994-12-31 1996-07-04 Bayer Ernst Prof Dr Gradienten - Injektions - Modul für Kapillar-HPLC, Kapillarelektrophorese und Elektrochromatographie
EP0990899B1 (en) 1998-05-25 2005-11-23 Agilent Technologies, Inc. (a Delaware corporation) Sample injector for a high-pressure liquid chromatograph
US6387234B1 (en) * 1998-08-31 2002-05-14 Iowa State University Research Foundation, Inc. Integrated multiplexed capillary electrophoresis system
US6190550B1 (en) * 1999-09-30 2001-02-20 Cohesive Technologies, Inc. Monitoring high performance liquid chromatography
US6290909B1 (en) 2000-04-13 2001-09-18 Sandia Corporation Sample injector for high pressure liquid chromatography
US6557575B1 (en) 2001-11-19 2003-05-06 Waters Investments Limited Fluid flow control freeze/thaw valve for narrow bore capillaries or microfluidic devices
AU2003272397A1 (en) 2002-09-16 2004-04-30 Waters Investments Limited Freeze-thaw valve limiting cryogenic usage

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0933502A (ja) * 1995-07-18 1997-02-07 Shimadzu Corp ガスクロマトグラフ装置

Also Published As

Publication number Publication date
US8173070B2 (en) 2012-05-08
GB2426216B (en) 2010-05-26
DE112005000128B4 (de) 2024-12-19
GB2426216A (en) 2006-11-22
WO2005071396A1 (en) 2005-08-04
GB0615960D0 (en) 2006-09-27
JP2007519007A (ja) 2007-07-12
DE112005000128T5 (de) 2007-05-03
GB0615976D0 (en) 2006-09-20
US20070283746A1 (en) 2007-12-13

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