DE3865831D1 - Fluessigproben-injektionseinrichtung. - Google Patents

Fluessigproben-injektionseinrichtung.

Info

Publication number
DE3865831D1
DE3865831D1 DE8888102007T DE3865831T DE3865831D1 DE 3865831 D1 DE3865831 D1 DE 3865831D1 DE 8888102007 T DE8888102007 T DE 8888102007T DE 3865831 T DE3865831 T DE 3865831T DE 3865831 D1 DE3865831 D1 DE 3865831D1
Authority
DE
Germany
Prior art keywords
port
piston
sample
unit
injection device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888102007T
Other languages
English (en)
Inventor
Fred Strohmeier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agilent Technologies Deutschland GmbH
Original Assignee
Hewlett Packard GmbH Germany
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hewlett Packard GmbH Germany filed Critical Hewlett Packard GmbH Germany
Application granted granted Critical
Publication of DE3865831D1 publication Critical patent/DE3865831D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/16Injection
    • G01N30/22Injection in high pressure liquid systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/36Control of physical parameters of the fluid carrier in high pressure liquid systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/24Automatic injection systems
DE8888102007T 1988-02-11 1988-02-11 Fluessigproben-injektionseinrichtung. Expired - Fee Related DE3865831D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88102007A EP0327658B1 (de) 1988-02-11 1988-02-11 Flüssigproben-Injektionseinrichtung

Publications (1)

Publication Number Publication Date
DE3865831D1 true DE3865831D1 (de) 1991-11-28

Family

ID=8198715

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888102007T Expired - Fee Related DE3865831D1 (de) 1988-02-11 1988-02-11 Fluessigproben-injektionseinrichtung.

Country Status (4)

Country Link
US (1) US4939943A (de)
EP (1) EP0327658B1 (de)
JP (1) JP2730951B2 (de)
DE (1) DE3865831D1 (de)

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EP0990899B1 (de) * 1998-05-25 2005-11-23 Agilent Technologies, Inc. (a Delaware corporation) Probeninjektionsvorrichtung für ein Hochleistungs-Flüssigkeitschromatograph
US6410914B1 (en) * 1999-03-05 2002-06-25 Bruker Daltonics Inc. Ionization chamber for atmospheric pressure ionization mass spectrometry
US6257052B1 (en) * 1999-07-06 2001-07-10 Digichrom, Inc Pump, sample feed and valving for high performance liquid chromatography (HPLC)
US6464849B1 (en) 1999-10-07 2002-10-15 Pepex Biomedical, L.L.C. Sensor for measuring a bioanalyte such as lactate
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WO2005071396A1 (en) * 2004-01-23 2005-08-04 Waters Investments Limited A sample injector system for liquid chromatography
US7596988B2 (en) * 2004-03-05 2009-10-06 Waters Technologies Corporation High performance liquid chromatography sample introduction optimized with bubble detection
US20060045810A1 (en) * 2004-08-27 2006-03-02 Konstantin Choikhet Sample injector for liquid analysis
US7563410B2 (en) * 2004-10-19 2009-07-21 Agilent Technologies, Inc. Solid phase extraction apparatus and method
US8881582B2 (en) 2005-01-31 2014-11-11 Waters Technologies Corporation Method and apparatus for sample injection in liquid chromatography
JP5070062B2 (ja) * 2005-01-31 2012-11-07 ウオーターズ・テクノロジーズ・コーポレイシヨン 液体クロマトグラフィにおけるサンプル注入のための方法および装置
JP4720305B2 (ja) * 2005-06-10 2011-07-13 株式会社島津製作所 オートサンプラ
JP4955342B2 (ja) * 2006-08-28 2012-06-20 株式会社日立ハイテクノロジーズ 液体クロマトグラフ装置及び試料導入装置
US20090126467A1 (en) * 2006-09-06 2009-05-21 Thermo Electron S.P.A. Washing device for liquid chromatography injectors
US7823468B2 (en) * 2007-01-26 2010-11-02 Teledyne Isco, Inc. Valve
US9044178B2 (en) 2007-08-30 2015-06-02 Pepex Biomedical, Llc Electrochemical sensor and method for manufacturing
WO2009032760A2 (en) 2007-08-30 2009-03-12 Pepex Biomedical Llc Electrochmical sensor and method for manufacturing
CN101680823B (zh) * 2007-09-28 2012-07-25 株式会社岛津制作所 进样方法
DE102007059651B4 (de) 2007-12-10 2017-05-24 Dionex Softron Gmbh Probengeber für die Hochleistungsflüssigkeitschromatographie
DE102008006266B4 (de) 2008-01-25 2011-06-09 Dionex Softron Gmbh Probengeber für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie
US8951377B2 (en) 2008-11-14 2015-02-10 Pepex Biomedical, Inc. Manufacturing electrochemical sensor module
WO2010056878A2 (en) 2008-11-14 2010-05-20 Pepex Biomedical, Llc Electrochemical sensor module
US8506740B2 (en) 2008-11-14 2013-08-13 Pepex Biomedical, Llc Manufacturing electrochemical sensor module
DE102009026640A1 (de) 2009-06-02 2009-10-15 Agilent Technologies Inc., Santa Clara Rückspülung eines Sitzes für einen Probeninjektor
JP5492985B2 (ja) 2009-06-03 2014-05-14 アジレント・テクノロジーズ・インク 中間バルブ状態における圧力差を均衡させる計量デバイスを有するサンプルインジェクター
JP5111476B2 (ja) 2009-10-26 2013-01-09 株式会社日立ハイテクノロジーズ 液体試料分析装置及び液体試料導入装置
JP2012117945A (ja) 2010-12-02 2012-06-21 Hitachi High-Technologies Corp 液体クロマトグラフ,液体クロマトグラフ用試料導入装置、および液体クロマトグラフ用試料導入装置の洗浄方法
GB2490148B (en) * 2011-04-20 2017-12-20 Agilent Technologies Inc Metering device with cartridge design to safely change metering head
DE102011075146A1 (de) 2011-05-03 2012-11-08 Legal Department, Ip Practice Group Agilent Technologies, Inc. Kapillarende als sitz für einen probeninjektor
WO2012159040A2 (en) 2011-05-19 2012-11-22 Pepex Biomedical Inc. Fluid management and patient monitoring system
WO2012162151A2 (en) 2011-05-20 2012-11-29 Pepex Biomedical, Inc. Manufacturing electrochemical sensor modules
US8800352B2 (en) 2011-07-15 2014-08-12 Thermo Finnigan Llc Method for automatic optimization of liquid chromatography autosampler
CH706929A1 (de) * 2012-09-11 2014-03-14 Werner Doebelin Ultra-Hochdruck-Spritzenpumpensystem für den Gradienten Betrieb im Bereich der HPLC.
DE102012217848A1 (de) 2012-09-28 2014-04-03 Agilent Technologies, Inc. - A Delaware Corporation - Injektionsventil zur Steuerung der Probenzufuhr an zwei Probenmesseinrichtungen
US11224367B2 (en) 2012-12-03 2022-01-18 Pepex Biomedical, Inc. Sensor module and method of using a sensor module
DE102013215065A1 (de) 2013-07-31 2015-02-05 Agilent Technologies Inc. Fluidventil mit ringförmiger Kanalstruktur
GB2540307B (en) 2014-03-31 2020-08-19 Agilent Technologies Inc Sealing moving with piston in a high-pressure pump
DE102014106551A1 (de) 2014-05-09 2015-11-12 Agilent Technologies, Inc. - A Delaware Corporation - In Probentrennen integriertes Spülen unter Wiederverwenden geförderten Fluids als Spülfluid
US11045124B2 (en) 2014-06-04 2021-06-29 Pepex Biomedical, Inc. Electrochemical sensors and methods for making electrochemical sensors using advanced printing technology
DE102014109551A1 (de) 2014-07-08 2016-01-14 Agilent Technologies, Inc. - A Delaware Corporation - Injektor mit in analytischen Pfad wahlweise hinein- oder herausschaltbarer Dosierpumpe
DE102014115087B4 (de) 2014-10-16 2017-03-30 Dionex Softron Gmbh Verfahren für einen Chromatographielauf in der Flüssigkeitschromatographie
GB2538103B (en) * 2015-05-08 2021-09-15 Agilent Technologies Inc Correcting sample metering inaccuracy due to thermally induced volume change in sample separation apparatus
DE202016100451U1 (de) 2015-06-25 2016-02-16 Dionex Softron Gmbh Probengeber für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie
DE102016101658B4 (de) 2016-01-29 2018-04-05 Dionex Softron Gmbh Probenvorkompressionsventil für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie
US10371141B1 (en) 2016-07-25 2019-08-06 Yury Zelechonok Gradient high pressure syringe pump
DE102016121515A1 (de) 2016-11-10 2018-05-17 Dionex Softron Gmbh Verfahren zum Einführen einer Probe in eine Trennsäule und entsprechendes System
DE102016121512A1 (de) 2016-11-10 2018-05-17 Dionex Softron Gmbh System, Verfahren und Verwendung der Flüssigkeitschromatografie
DE102017125486A1 (de) 2017-10-30 2018-01-04 Agilent Technologies, Inc. - A Delaware Corporation - Injektor mit Fluidzuführung und Mobilphasenabführung
DE102020107910A1 (de) 2019-04-04 2020-10-08 Dionex Softron Gmbh Flüssigkeitschromatografieverfahren, System und Verwendung zur Probennahme
US11835496B2 (en) 2019-12-23 2023-12-05 Waters Technologies Corporation Sample metering and injection for liquid chromatography
DE102020133427A1 (de) 2020-12-14 2022-06-15 Agilent Technologies, Inc. - A Delaware Corporation - Fluidisches Rotationsventil
CN117153659B (zh) * 2023-10-26 2023-12-26 常州磐诺仪器有限公司 一种液质联用质谱仪辅助进样装置

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AT286684B (de) * 1965-05-19 1970-12-28 Ceskoslovenska Akademie Ved Einrichtung zur Probenahme für automatische, physikalisch-chemische Analysatoren
US3831618A (en) * 1972-12-22 1974-08-27 Abbott Lab Apparatus for the precision metering of fluids
US3960003A (en) * 1974-11-11 1976-06-01 The Upjohn Company Automatic system for high pressure liquid chromatography
JPS5330390A (en) * 1976-09-02 1978-03-22 Nippon Bunko Kogyo Kk Liquid chromatograph
US4059009A (en) * 1976-09-10 1977-11-22 Micromeritics Instrument Corporation Liquid chromatography system
USRE31608E (en) * 1977-01-21 1984-06-19 Altex Scientific, Inc. Fluid pump mechanism
US4117727A (en) * 1977-12-12 1978-10-03 Friswell David R Bubble sensor and method
US4242909A (en) * 1979-04-19 1981-01-06 Rheodyne Incorporated Sample injector
US4347131A (en) * 1981-04-28 1982-08-31 Robert Brownlee Liquid chromatographic pump module
US4476734A (en) * 1983-03-07 1984-10-16 International Business Machines Corporation Wet needle sampler for use with a gas chromatograph
JPS6176955A (ja) * 1984-09-21 1986-04-19 Hitachi Ltd 液体試料注入装置
US4812183A (en) * 1985-12-30 1989-03-14 Aluminum Company Of America Coated sheet stock
US4713974A (en) * 1986-04-18 1987-12-22 Varian Associates, Inc./Scientific Systems, Inc. Autosampler

Also Published As

Publication number Publication date
EP0327658B1 (de) 1991-10-23
US4939943A (en) 1990-07-10
JP2730951B2 (ja) 1998-03-25
JPH01248055A (ja) 1989-10-03
EP0327658A1 (de) 1989-08-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AGILENT TECHNOLOGIES DEUTSCHLAND GMBH, 71034 BOEBL

8339 Ceased/non-payment of the annual fee