DE3865831D1 - Fluessigproben-injektionseinrichtung. - Google Patents
Fluessigproben-injektionseinrichtung.Info
- Publication number
- DE3865831D1 DE3865831D1 DE8888102007T DE3865831T DE3865831D1 DE 3865831 D1 DE3865831 D1 DE 3865831D1 DE 8888102007 T DE8888102007 T DE 8888102007T DE 3865831 T DE3865831 T DE 3865831T DE 3865831 D1 DE3865831 D1 DE 3865831D1
- Authority
- DE
- Germany
- Prior art keywords
- port
- piston
- sample
- unit
- injection device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
- G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/22—Injection in high pressure liquid systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/36—Control of physical parameters of the fluid carrier in high pressure liquid systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/24—Automatic injection systems
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Fluid Mechanics (AREA)
- Sampling And Sample Adjustment (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Reciprocating Pumps (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88102007A EP0327658B1 (de) | 1988-02-11 | 1988-02-11 | Flüssigproben-Injektionseinrichtung |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3865831D1 true DE3865831D1 (de) | 1991-11-28 |
Family
ID=8198715
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888102007T Expired - Fee Related DE3865831D1 (de) | 1988-02-11 | 1988-02-11 | Fluessigproben-injektionseinrichtung. |
Country Status (4)
Country | Link |
---|---|
US (1) | US4939943A (de) |
EP (1) | EP0327658B1 (de) |
JP (1) | JP2730951B2 (de) |
DE (1) | DE3865831D1 (de) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3934699A1 (de) * | 1989-10-18 | 1991-04-25 | Bodenseewerk Perkin Elmer Co | Dosiereinrichtung fuer analysengeraete |
US5814742A (en) * | 1996-10-11 | 1998-09-29 | L C Packings, Nederland B.V. | Fully automated micro-autosampler for micro, capillary and nano high performance liquid chromatography |
ES2128243B1 (es) * | 1996-11-11 | 2000-04-01 | Tinto Moliner Antonio | Jeringa de estanqueidad constante. |
US5920006A (en) * | 1997-06-16 | 1999-07-06 | Digichrom, Inc. | Liquid chromatographic pump and valve assembly |
US6117290A (en) * | 1997-09-26 | 2000-09-12 | Pepex Biomedical, Llc | System and method for measuring a bioanalyte such as lactate |
EP0990899B1 (de) * | 1998-05-25 | 2005-11-23 | Agilent Technologies, Inc. (a Delaware corporation) | Probeninjektionsvorrichtung für ein Hochleistungs-Flüssigkeitschromatograph |
US6410914B1 (en) * | 1999-03-05 | 2002-06-25 | Bruker Daltonics Inc. | Ionization chamber for atmospheric pressure ionization mass spectrometry |
US6257052B1 (en) * | 1999-07-06 | 2001-07-10 | Digichrom, Inc | Pump, sample feed and valving for high performance liquid chromatography (HPLC) |
US6464849B1 (en) | 1999-10-07 | 2002-10-15 | Pepex Biomedical, L.L.C. | Sensor for measuring a bioanalyte such as lactate |
US6802228B2 (en) * | 2001-03-29 | 2004-10-12 | Dong C. Liang | Microsample analysis system using syringe pump and injection port |
US6382035B1 (en) | 2001-04-02 | 2002-05-07 | Rheodyne, Lp | Multi-valving sample injection apparatus |
WO2005071396A1 (en) * | 2004-01-23 | 2005-08-04 | Waters Investments Limited | A sample injector system for liquid chromatography |
WO2005091936A2 (en) * | 2004-03-05 | 2005-10-06 | Waters Investments Limited | High performance liquid chromatography sample introduction optimized with bubble detection |
US20060045810A1 (en) * | 2004-08-27 | 2006-03-02 | Konstantin Choikhet | Sample injector for liquid analysis |
US7563410B2 (en) * | 2004-10-19 | 2009-07-21 | Agilent Technologies, Inc. | Solid phase extraction apparatus and method |
JP5070062B2 (ja) * | 2005-01-31 | 2012-11-07 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 液体クロマトグラフィにおけるサンプル注入のための方法および装置 |
US8881582B2 (en) | 2005-01-31 | 2014-11-11 | Waters Technologies Corporation | Method and apparatus for sample injection in liquid chromatography |
JP4720305B2 (ja) * | 2005-06-10 | 2011-07-13 | 株式会社島津製作所 | オートサンプラ |
JP4955342B2 (ja) * | 2006-08-28 | 2012-06-20 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフ装置及び試料導入装置 |
WO2008029422A1 (en) * | 2006-09-06 | 2008-03-13 | Thermo Electon S.P.A. | Washing device for liquid chromatography injectors |
US7823468B2 (en) * | 2007-01-26 | 2010-11-02 | Teledyne Isco, Inc. | Valve |
US8702932B2 (en) | 2007-08-30 | 2014-04-22 | Pepex Biomedical, Inc. | Electrochemical sensor and method for manufacturing |
WO2009051901A2 (en) | 2007-08-30 | 2009-04-23 | Pepex Biomedical, Llc | Electrochemical sensor and method for manufacturing |
US8234939B2 (en) * | 2007-09-28 | 2012-08-07 | Shimadzu Corporation | Sample introduction method |
DE102007059651B4 (de) | 2007-12-10 | 2017-05-24 | Dionex Softron Gmbh | Probengeber für die Hochleistungsflüssigkeitschromatographie |
DE102008006266B4 (de) | 2008-01-25 | 2011-06-09 | Dionex Softron Gmbh | Probengeber für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie |
WO2010056878A2 (en) | 2008-11-14 | 2010-05-20 | Pepex Biomedical, Llc | Electrochemical sensor module |
US8951377B2 (en) | 2008-11-14 | 2015-02-10 | Pepex Biomedical, Inc. | Manufacturing electrochemical sensor module |
US8506740B2 (en) | 2008-11-14 | 2013-08-13 | Pepex Biomedical, Llc | Manufacturing electrochemical sensor module |
DE102009026640A1 (de) | 2009-06-02 | 2009-10-15 | Agilent Technologies Inc., Santa Clara | Rückspülung eines Sitzes für einen Probeninjektor |
CN102460145B (zh) * | 2009-06-03 | 2015-04-29 | 安捷伦科技有限公司 | 使中间阀状态的压力差平衡的计量装置的样品注射器 |
JP5111476B2 (ja) | 2009-10-26 | 2013-01-09 | 株式会社日立ハイテクノロジーズ | 液体試料分析装置及び液体試料導入装置 |
JP2012117945A (ja) | 2010-12-02 | 2012-06-21 | Hitachi High-Technologies Corp | 液体クロマトグラフ,液体クロマトグラフ用試料導入装置、および液体クロマトグラフ用試料導入装置の洗浄方法 |
GB2490148B (en) * | 2011-04-20 | 2017-12-20 | Agilent Technologies Inc | Metering device with cartridge design to safely change metering head |
DE102011075146A1 (de) | 2011-05-03 | 2012-11-08 | Legal Department, Ip Practice Group Agilent Technologies, Inc. | Kapillarende als sitz für einen probeninjektor |
WO2012159040A2 (en) | 2011-05-19 | 2012-11-22 | Pepex Biomedical Inc. | Fluid management and patient monitoring system |
US9504162B2 (en) | 2011-05-20 | 2016-11-22 | Pepex Biomedical, Inc. | Manufacturing electrochemical sensor modules |
US8800352B2 (en) | 2011-07-15 | 2014-08-12 | Thermo Finnigan Llc | Method for automatic optimization of liquid chromatography autosampler |
CH706929A1 (de) * | 2012-09-11 | 2014-03-14 | Werner Doebelin | Ultra-Hochdruck-Spritzenpumpensystem für den Gradienten Betrieb im Bereich der HPLC. |
DE102012217848A1 (de) | 2012-09-28 | 2014-04-03 | Agilent Technologies, Inc. - A Delaware Corporation - | Injektionsventil zur Steuerung der Probenzufuhr an zwei Probenmesseinrichtungen |
BR112015012958B1 (pt) | 2012-12-03 | 2022-03-15 | Pepex Biomedical, Inc | Módulo sensor para detectar um analito em uma amostra de sangue |
DE102013215065A1 (de) | 2013-07-31 | 2015-02-05 | Agilent Technologies Inc. | Fluidventil mit ringförmiger Kanalstruktur |
WO2015150863A1 (en) | 2014-03-31 | 2015-10-08 | Agilent Technologies, Inc. | Sealing moving with piston in a high-pressure pump |
DE102014106551A1 (de) | 2014-05-09 | 2015-11-12 | Agilent Technologies, Inc. - A Delaware Corporation - | In Probentrennen integriertes Spülen unter Wiederverwenden geförderten Fluids als Spülfluid |
WO2015187959A1 (en) | 2014-06-04 | 2015-12-10 | Pepex Biomedical, Inc. | Electrochemical sensors and methods for making electrochemical sensors using advanced printing technology |
DE102014109551A1 (de) | 2014-07-08 | 2016-01-14 | Agilent Technologies, Inc. - A Delaware Corporation - | Injektor mit in analytischen Pfad wahlweise hinein- oder herausschaltbarer Dosierpumpe |
DE102014115087B4 (de) | 2014-10-16 | 2017-03-30 | Dionex Softron Gmbh | Verfahren für einen Chromatographielauf in der Flüssigkeitschromatographie |
GB2538103B (en) * | 2015-05-08 | 2021-09-15 | Agilent Technologies Inc | Correcting sample metering inaccuracy due to thermally induced volume change in sample separation apparatus |
DE202016100451U1 (de) | 2015-06-25 | 2016-02-16 | Dionex Softron Gmbh | Probengeber für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie |
DE102016101658B4 (de) | 2016-01-29 | 2018-04-05 | Dionex Softron Gmbh | Probenvorkompressionsventil für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie |
US10371141B1 (en) | 2016-07-25 | 2019-08-06 | Yury Zelechonok | Gradient high pressure syringe pump |
DE102016121512A1 (de) | 2016-11-10 | 2018-05-17 | Dionex Softron Gmbh | System, Verfahren und Verwendung der Flüssigkeitschromatografie |
DE102016121515A1 (de) | 2016-11-10 | 2018-05-17 | Dionex Softron Gmbh | Verfahren zum Einführen einer Probe in eine Trennsäule und entsprechendes System |
DE102017125486A1 (de) | 2017-10-30 | 2018-01-04 | Agilent Technologies, Inc. - A Delaware Corporation - | Injektor mit Fluidzuführung und Mobilphasenabführung |
CN109126203A (zh) * | 2018-10-15 | 2019-01-04 | 上海昂鹭生物技术有限公司 | 一种用于有机溶液的自动过膜装置 |
DE102020107910A1 (de) | 2019-04-04 | 2020-10-08 | Dionex Softron Gmbh | Flüssigkeitschromatografieverfahren, System und Verwendung zur Probennahme |
EP4081795A1 (de) | 2019-12-23 | 2022-11-02 | Waters Technologies Corporation | Probendosierung und injektion für flüssigchromatografie |
DE102020133427A1 (de) | 2020-12-14 | 2022-06-15 | Agilent Technologies, Inc. - A Delaware Corporation - | Fluidisches Rotationsventil |
CN117153659B (zh) * | 2023-10-26 | 2023-12-26 | 常州磐诺仪器有限公司 | 一种液质联用质谱仪辅助进样装置 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT286684B (de) * | 1965-05-19 | 1970-12-28 | Ceskoslovenska Akademie Ved | Einrichtung zur Probenahme für automatische, physikalisch-chemische Analysatoren |
US3831618A (en) * | 1972-12-22 | 1974-08-27 | Abbott Lab | Apparatus for the precision metering of fluids |
US3960003A (en) * | 1974-11-11 | 1976-06-01 | The Upjohn Company | Automatic system for high pressure liquid chromatography |
JPS5330390A (en) * | 1976-09-02 | 1978-03-22 | Nippon Bunko Kogyo Kk | Liquid chromatograph |
US4059009A (en) * | 1976-09-10 | 1977-11-22 | Micromeritics Instrument Corporation | Liquid chromatography system |
USRE31608E (en) * | 1977-01-21 | 1984-06-19 | Altex Scientific, Inc. | Fluid pump mechanism |
US4117727A (en) * | 1977-12-12 | 1978-10-03 | Friswell David R | Bubble sensor and method |
US4242909A (en) * | 1979-04-19 | 1981-01-06 | Rheodyne Incorporated | Sample injector |
US4347131A (en) * | 1981-04-28 | 1982-08-31 | Robert Brownlee | Liquid chromatographic pump module |
US4476734A (en) * | 1983-03-07 | 1984-10-16 | International Business Machines Corporation | Wet needle sampler for use with a gas chromatograph |
JPS6176955A (ja) * | 1984-09-21 | 1986-04-19 | Hitachi Ltd | 液体試料注入装置 |
US4812183A (en) * | 1985-12-30 | 1989-03-14 | Aluminum Company Of America | Coated sheet stock |
US4713974A (en) * | 1986-04-18 | 1987-12-22 | Varian Associates, Inc./Scientific Systems, Inc. | Autosampler |
-
1988
- 1988-02-11 DE DE8888102007T patent/DE3865831D1/de not_active Expired - Fee Related
- 1988-02-11 EP EP88102007A patent/EP0327658B1/de not_active Expired - Lifetime
-
1989
- 1989-02-02 US US07/305,888 patent/US4939943A/en not_active Expired - Lifetime
- 1989-02-10 JP JP1032548A patent/JP2730951B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0327658B1 (de) | 1991-10-23 |
JPH01248055A (ja) | 1989-10-03 |
US4939943A (en) | 1990-07-10 |
JP2730951B2 (ja) | 1998-03-25 |
EP0327658A1 (de) | 1989-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: AGILENT TECHNOLOGIES DEUTSCHLAND GMBH, 71034 BOEBL |
|
8339 | Ceased/non-payment of the annual fee |