JP4727748B2 - 神経保護医薬組成物の製造のためのプロインスリンの使用、それを含む治療組成物、およびそれらの応用 - Google Patents

神経保護医薬組成物の製造のためのプロインスリンの使用、それを含む治療組成物、およびそれらの応用 Download PDF

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JP4727748B2
JP4727748B2 JP2009511534A JP2009511534A JP4727748B2 JP 4727748 B2 JP4727748 B2 JP 4727748B2 JP 2009511534 A JP2009511534 A JP 2009511534A JP 2009511534 A JP2009511534 A JP 2009511534A JP 4727748 B2 JP4727748 B2 JP 4727748B2
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Prior art keywords
proinsulin
nucleotide sequence
compound
human
seq
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JP2009511534A
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Japanese (ja)
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JP2009537612A5 (enExample
JP2009537612A (ja
Inventor
エンリケ、ホタ.デ、ラ、ロサ、カノ
マリア、フロラ、デ、パブロ、ダビラ
パトリシア、ボヤ、トレモレダ
シルビア、コロチャノ、サンチェス
ペドロ、デ、ラ、ビリャ、ポロ
リマ、バルオウム、タンノウス
ファティマ、ボッシュ、トゥベルト
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Consejo Superior de Investigaciones Cientificas CSIC
Universitat Autonoma de Barcelona UAB
Universidad de Alcala de Henares UAH
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Consejo Superior de Investigaciones Cientificas CSIC
Universitat Autonoma de Barcelona UAB
Universidad de Alcala de Henares UAH
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2009511534A 2006-05-22 2007-05-21 神経保護医薬組成物の製造のためのプロインスリンの使用、それを含む治療組成物、およびそれらの応用 Expired - Fee Related JP4727748B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP200601314 2006-05-22
ES200601314A ES2331342B1 (es) 2006-05-22 2006-05-22 Uso de la proinsulina para la elaboracion de una composicion farmaceutica neuroprotectora, composicion terapeutica que la contiene y sus aplicaciones.
PCT/ES2007/070097 WO2007135220A1 (es) 2006-05-22 2007-05-21 Uso de la proinsulina para la elaboración de una composición farmacéutica neuroprotectora, composición terapéutica que la contiene y sus aplicaciones

Publications (3)

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JP2009537612A JP2009537612A (ja) 2009-10-29
JP2009537612A5 JP2009537612A5 (enExample) 2010-02-12
JP4727748B2 true JP4727748B2 (ja) 2011-07-20

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JP2009511534A Expired - Fee Related JP4727748B2 (ja) 2006-05-22 2007-05-21 神経保護医薬組成物の製造のためのプロインスリンの使用、それを含む治療組成物、およびそれらの応用

Country Status (7)

Country Link
US (1) US20100330042A1 (enExample)
EP (1) EP2042189B1 (enExample)
JP (1) JP4727748B2 (enExample)
AU (1) AU2007253212B2 (enExample)
CA (1) CA2652983C (enExample)
ES (2) ES2331342B1 (enExample)
WO (1) WO2007135220A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110021974A1 (en) * 2010-10-05 2011-01-27 Shantha Totada R Retinitis pigmentosa treatment and prophalaxis
EP2872183B1 (en) 2012-07-11 2018-09-26 The Trustees Of The University Of Pennsylvania Aav-mediated gene therapy for rpgr x-linked retinal degeneration

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1176160A (en) * 1981-08-27 1984-10-16 Ronald E. Chance Human proinsulin pharmaceutical formulations
US5652214A (en) * 1989-06-05 1997-07-29 Cephalon, Inc. Treating disorders by application of insulin-like growth factors and analogs
US5667968A (en) * 1989-08-30 1997-09-16 Regeneron Pharmaceuticals, Inc. Prevention of retinal injury and degeneration by specific factors
EP0788512B1 (en) * 1994-07-08 1999-03-24 The Trustees Of Dartmouth College Proinsulin peptide compounds for detecting and treating type i diabetes
JP2003526321A (ja) * 1998-07-15 2003-09-09 ウイスコンシン アラムナイ リサーチ フオンデーシヨン 合成ベータ細胞による糖尿病の治療
DE10055857A1 (de) * 2000-11-10 2002-08-22 Creative Peptides Sweden Ab Dj Neue pharmazeutische Depotformulierung
US7312192B2 (en) * 2001-09-07 2007-12-25 Biocon Limited Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same
JP2005534650A (ja) * 2002-06-11 2005-11-17 ザ バーナム インスティテュート エリスロポイエチンおよびインスリン様増殖因子の神経保護的相乗作用

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Publication number Publication date
CA2652983C (en) 2016-07-19
ES2331342A1 (es) 2009-12-29
EP2042189B1 (en) 2013-06-26
WO2007135220A1 (es) 2007-11-29
CA2652983A1 (en) 2007-11-29
AU2007253212B2 (en) 2012-09-27
US20100330042A1 (en) 2010-12-30
EP2042189A1 (en) 2009-04-01
AU2007253212A1 (en) 2007-11-29
JP2009537612A (ja) 2009-10-29
ES2331342B1 (es) 2010-10-13
ES2433389T3 (es) 2013-12-10
EP2042189A4 (en) 2010-02-17

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