JP4708332B2 - 推進剤としてヒドロフルオロアルカンを用いる計量式吸入器のための調合物 - Google Patents

推進剤としてヒドロフルオロアルカンを用いる計量式吸入器のための調合物 Download PDF

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Publication number
JP4708332B2
JP4708332B2 JP2006507344A JP2006507344A JP4708332B2 JP 4708332 B2 JP4708332 B2 JP 4708332B2 JP 2006507344 A JP2006507344 A JP 2006507344A JP 2006507344 A JP2006507344 A JP 2006507344A JP 4708332 B2 JP4708332 B2 JP 4708332B2
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formulation
propellant
water
ethanol
mass
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Japanese (ja)
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JP2006520797A5 (enrdf_load_stackoverflow
JP2006520797A (ja
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ジョージ ディストファーノ
キャナヴォ リンダ ジーン ケラッシュ
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ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
JP2006507344A 2003-03-20 2004-03-19 推進剤としてヒドロフルオロアルカンを用いる計量式吸入器のための調合物 Expired - Lifetime JP4708332B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45611303P 2003-03-20 2003-03-20
US60/456,113 2003-03-20
PCT/US2004/008375 WO2004084858A2 (en) 2003-03-20 2004-03-19 Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants

Publications (3)

Publication Number Publication Date
JP2006520797A JP2006520797A (ja) 2006-09-14
JP2006520797A5 JP2006520797A5 (enrdf_load_stackoverflow) 2007-05-17
JP4708332B2 true JP4708332B2 (ja) 2011-06-22

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JP2006507344A Expired - Lifetime JP4708332B2 (ja) 2003-03-20 2004-03-19 推進剤としてヒドロフルオロアルカンを用いる計量式吸入器のための調合物

Country Status (28)

Country Link
US (1) US7914770B2 (enrdf_load_stackoverflow)
EP (1) EP1608336B1 (enrdf_load_stackoverflow)
JP (1) JP4708332B2 (enrdf_load_stackoverflow)
KR (1) KR101113003B1 (enrdf_load_stackoverflow)
CN (1) CN1761455A (enrdf_load_stackoverflow)
AT (1) ATE390125T1 (enrdf_load_stackoverflow)
AU (1) AU2004224367B2 (enrdf_load_stackoverflow)
BR (1) BRPI0408547A (enrdf_load_stackoverflow)
CA (1) CA2519523C (enrdf_load_stackoverflow)
CO (1) CO5640070A2 (enrdf_load_stackoverflow)
CY (1) CY1108137T1 (enrdf_load_stackoverflow)
DE (1) DE602004012718T2 (enrdf_load_stackoverflow)
DK (1) DK1608336T3 (enrdf_load_stackoverflow)
EA (1) EA009087B1 (enrdf_load_stackoverflow)
EC (1) ECSP056029A (enrdf_load_stackoverflow)
ES (1) ES2304616T3 (enrdf_load_stackoverflow)
HR (1) HRP20050822B1 (enrdf_load_stackoverflow)
ME (1) ME00420B (enrdf_load_stackoverflow)
MX (1) MXPA05009920A (enrdf_load_stackoverflow)
NO (1) NO336457B1 (enrdf_load_stackoverflow)
NZ (1) NZ542957A (enrdf_load_stackoverflow)
PL (1) PL1608336T3 (enrdf_load_stackoverflow)
PT (1) PT1608336E (enrdf_load_stackoverflow)
RS (1) RS51663B (enrdf_load_stackoverflow)
SI (1) SI1608336T1 (enrdf_load_stackoverflow)
UA (1) UA89751C2 (enrdf_load_stackoverflow)
WO (1) WO2004084858A2 (enrdf_load_stackoverflow)
ZA (1) ZA200506463B (enrdf_load_stackoverflow)

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US20060140873A1 (en) * 2004-12-27 2006-06-29 Chang Heng W Aerosol pharmaceutical compositions
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
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DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006014433A1 (de) * 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
WO2008047239A2 (en) * 2006-09-21 2008-04-24 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
WO2009026178A2 (en) * 2007-08-17 2009-02-26 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US8119694B2 (en) 2008-08-15 2012-02-21 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
JP5670421B2 (ja) 2009-03-31 2015-02-18 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング コンポーネント表面のコーティング方法
EP3508239B1 (de) 2009-05-18 2020-12-23 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
EP2504052B1 (en) 2009-11-25 2022-07-27 Boehringer Ingelheim International GmbH Nebulizer
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
US9943654B2 (en) 2010-06-24 2018-04-17 Boehringer Ingelheim International Gmbh Nebulizer
US20120204871A1 (en) * 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
CN102798044B (zh) * 2012-08-02 2014-09-10 深圳市华星光电技术有限公司 侧入式背光模组
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
LT3139982T (lt) 2014-05-07 2022-04-11 Boehringer Ingelheim International Gmbh Rūkinis purkštuvas
EP3139979B1 (en) 2014-05-07 2023-07-05 Boehringer Ingelheim International GmbH Unit, nebulizer and method
ES2874029T3 (es) 2014-05-07 2021-11-04 Boehringer Ingelheim Int Nebulizador
US20180071231A1 (en) * 2015-04-10 2018-03-15 3M Innovative Properties Company Formulation and aerosol canisters, inhalers, and the like containing the formulation
GB2573297A (en) * 2018-04-30 2019-11-06 Mexichem Fluor Sa De Cv Pharmaceutical composition
WO2021216779A1 (en) * 2020-04-21 2021-10-28 Amphastar Pharmaceuticals, Inc. Anti-viral pharmaceutical formulations administered via devices for lung targeted delivery

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US20030008369A1 (en) * 1999-03-03 2003-01-09 Board Of Regents, The University Of Texas System Genetic and epigenetic manipulation of ABC transporters and ecto-phosphatases
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Also Published As

Publication number Publication date
ECSP056029A (es) 2006-01-27
NZ542957A (en) 2008-09-26
ME00420B (me) 2011-12-20
CN1761455A (zh) 2006-04-19
HRP20050822B1 (hr) 2013-09-30
ZA200506463B (en) 2006-04-26
EP1608336A2 (en) 2005-12-28
CA2519523C (en) 2012-03-13
RS51663B (en) 2011-10-31
UA89751C2 (ru) 2010-03-10
NO336457B1 (no) 2015-08-31
EA009087B1 (ru) 2007-10-26
WO2004084858A3 (en) 2004-11-04
KR20050111382A (ko) 2005-11-24
CY1108137T1 (el) 2014-02-12
RS20050705A (sr) 2008-04-04
CO5640070A2 (es) 2006-05-31
MXPA05009920A (es) 2005-11-04
DE602004012718T2 (de) 2009-05-07
ATE390125T1 (de) 2008-04-15
EP1608336B1 (en) 2008-03-26
NO20054839L (no) 2005-10-19
US20040184994A1 (en) 2004-09-23
HRP20050822A2 (en) 2006-10-31
ES2304616T3 (es) 2008-10-16
KR101113003B1 (ko) 2012-02-24
US7914770B2 (en) 2011-03-29
DK1608336T3 (da) 2008-06-02
BRPI0408547A (pt) 2006-03-07
PT1608336E (pt) 2008-04-21
AU2004224367B2 (en) 2009-10-08
DE602004012718D1 (de) 2008-05-08
EA200501363A1 (ru) 2006-04-28
WO2004084858A2 (en) 2004-10-07
JP2006520797A (ja) 2006-09-14
AU2004224367A1 (en) 2004-10-07
SI1608336T1 (sl) 2008-08-31
CA2519523A1 (en) 2004-10-07
PL1608336T3 (pl) 2008-09-30

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