JP4664595B2 - 活性成分の放出を制御する治療システム - Google Patents

活性成分の放出を制御する治療システム Download PDF

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Publication number
JP4664595B2
JP4664595B2 JP2003574172A JP2003574172A JP4664595B2 JP 4664595 B2 JP4664595 B2 JP 4664595B2 JP 2003574172 A JP2003574172 A JP 2003574172A JP 2003574172 A JP2003574172 A JP 2003574172A JP 4664595 B2 JP4664595 B2 JP 4664595B2
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coating
layer
tablet
release
film
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Japanese (ja)
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JP2005526757A (ja
JP2005526757A5 (https=
Inventor
ローレッタ マギー
ウバルド コンテ
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ヤゴテック アーゲー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2003574172A 2002-03-12 2003-03-12 活性成分の放出を制御する治療システム Expired - Fee Related JP4664595B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002MI000514A ITMI20020514A1 (it) 2002-03-12 2002-03-12 Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
PCT/EP2003/002536 WO2003075897A1 (en) 2002-03-12 2003-03-12 Therapeutic system for the controlled release of active ingredients

Publications (3)

Publication Number Publication Date
JP2005526757A JP2005526757A (ja) 2005-09-08
JP2005526757A5 JP2005526757A5 (https=) 2006-04-20
JP4664595B2 true JP4664595B2 (ja) 2011-04-06

Family

ID=11449490

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003574172A Expired - Fee Related JP4664595B2 (ja) 2002-03-12 2003-03-12 活性成分の放出を制御する治療システム

Country Status (12)

Country Link
US (1) US20050095295A1 (https=)
EP (1) EP1482915B1 (https=)
JP (1) JP4664595B2 (https=)
CN (1) CN100528146C (https=)
AT (1) ATE454887T1 (https=)
AU (1) AU2003239789A1 (https=)
CA (1) CA2478406C (https=)
DE (1) DE60330949D1 (https=)
DK (1) DK1482915T3 (https=)
ES (1) ES2339438T3 (https=)
IT (1) ITMI20020514A1 (https=)
WO (1) WO2003075897A1 (https=)

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EP1429744A1 (en) 2001-09-21 2004-06-23 Egalet A/S Morphine polymer release system
US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
GB0203296D0 (en) 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
US8637512B2 (en) 2002-07-29 2014-01-28 Glaxo Group Limited Formulations and method of treatment
WO2004084868A1 (en) 2003-03-26 2004-10-07 Egalet A/S Morphine controlled release system
KR101164881B1 (ko) * 2003-09-19 2012-07-23 썬 파마슈티컬 인더스트리스 리미티드 경구용 약물 전달 시스템
US10226428B2 (en) 2003-09-19 2019-03-12 Sun Pharma Advanced Research Company Ltd. Oral drug delivery system
US10213387B2 (en) 2003-09-19 2019-02-26 Sun Pharma Advanced Research Company Ltd. Oral drug delivery system
CA2607272A1 (en) * 2005-05-09 2006-11-16 Azur Pharma Limited Formulations of mast cell stabilizing agents for delivery to the colon
NZ563846A (en) * 2005-06-03 2010-03-26 Egalet As A drug delivery system for delivering active substances dispersed in a dispersion medium
US8231902B2 (en) * 2005-11-18 2012-07-31 Accu-Break Technologies, Inc. Segmented pharmaceutical dosage forms
MX2008016349A (es) * 2006-06-19 2009-01-28 Accu Break Technologies Inc Formas segmentadas de dosificacion farmaceutica.
US8821928B2 (en) 2007-06-04 2014-09-02 Egalet Ltd. Controlled release pharmaceutical compositions for prolonged effect
CN102026628A (zh) * 2008-02-15 2011-04-20 太阳医药高级研发有限公司 具有降低崩裂效果的口服控释片剂
AU2009308885A1 (en) * 2008-10-31 2010-05-06 Mcneil-Ppc, Inc. Osmotic tablet with a compressed outer coating
CA2751627A1 (en) 2009-02-06 2010-08-12 Egalet Ltd. Pharmaceutical compositions resistant to abuse
CA2751667C (en) 2009-02-06 2016-12-13 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
US9622979B2 (en) * 2011-06-29 2017-04-18 Sun Pharmaceutical Industries Limited Multilayered dosage form
AU2013285988A1 (en) 2012-07-06 2015-02-12 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
CN104490838B (zh) * 2014-11-20 2017-03-01 河北医科大学 一种骨架型缓控释片剂及其制备方法和应用
WO2017136617A1 (en) 2016-02-04 2017-08-10 Cinrx Pharma, Llc Deuterated domperidone compositions and methods for therapy of disorders
US11364226B2 (en) 2017-06-30 2022-06-21 Cinrx Pharma, Llc Deuterated domperidone compositions, methods, and preparation
CA3023278C (en) * 2016-05-05 2019-04-30 Triastek, Inc. Controlled release dosage form
EA201992116A1 (ru) 2017-03-08 2020-01-29 СИНРКС ФАРМА, ЭлЭлСи Фармацевтические составы флороглюцинола и триметилфлороглюцинола
US12478612B2 (en) 2017-06-30 2025-11-25 Cindome Pharma, Inc. Deuterated domperidone compositions, methods, and preparation
JP7034343B2 (ja) * 2018-06-27 2022-03-11 アムニール コンプレックス プロダクツ リサーチ エルエルシー 自己調節性の浸透性胃保持性薬物送達システム
WO2020027927A1 (en) * 2018-07-30 2020-02-06 Insta Therapeutics, Inc. Sublingual diltiazem and methods of use
CN113274363B (zh) * 2021-04-29 2023-02-10 珠海润都制药股份有限公司 一种吲达帕胺制剂

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GB1478759A (en) * 1974-11-18 1977-07-06 Alza Corp Process for forming outlet passageways in pills using a laser
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
IT1201136B (it) * 1987-01-13 1989-01-27 Resa Farma Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive
US4810502A (en) * 1987-02-27 1989-03-07 Alza Corporation Pseudoephedrine brompheniramine therapy
IT1237904B (it) * 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
US5256440A (en) * 1992-06-22 1993-10-26 Merck & Co., Inc. Process for producing a tablet core aperture
US5376771A (en) * 1992-07-07 1994-12-27 Merck & Co., Inc. High speed process for preparing orifices in pharmaceutical dosage forms
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
IT1264517B1 (it) * 1993-05-31 1996-09-24 Ekita Investments Nv Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati
CN2213539Y (zh) * 1994-04-29 1995-11-29 天津市激光技术研究所 包衣上带有小孔的缓释药片
IT1282576B1 (it) * 1996-02-06 1998-03-31 Jagotec Ag Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili
US5783793A (en) * 1996-02-29 1998-07-21 Merck & Co., Inc. Process for producing a plurality of holes in dosage forms using a laser beam deflected by an acousto-optic deflector
IL128043A (en) * 1997-05-30 2004-08-31 Osmotica Corp Multi-layered osmotic device for controlled delivery of active agents
US6004584A (en) * 1998-03-02 1999-12-21 The Procter & Gamble Company Highly absorbent body powders
CA2378829A1 (en) * 1999-07-20 2001-01-25 Merck & Co., Inc. Sustained release drug dispersion delivery device
AR026148A1 (es) * 2000-01-21 2003-01-29 Osmotica Argentina S A Dispositivo osmotico con pasaje preformado que aumenta de tamano
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento

Also Published As

Publication number Publication date
WO2003075897A1 (en) 2003-09-18
CA2478406C (en) 2011-02-08
JP2005526757A (ja) 2005-09-08
CN1649571A (zh) 2005-08-03
AU2003239789A1 (en) 2003-09-22
CA2478406A1 (en) 2003-09-18
US20050095295A1 (en) 2005-05-05
ES2339438T3 (es) 2010-05-20
EP1482915B1 (en) 2010-01-13
ATE454887T1 (de) 2010-01-15
DK1482915T3 (da) 2010-04-19
EP1482915A1 (en) 2004-12-08
CN100528146C (zh) 2009-08-19
ITMI20020514A1 (it) 2003-09-12
ITMI20020514A0 (it) 2002-03-12
DE60330949D1 (de) 2010-03-04

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