JP4664499B2 - 共溶媒処方物 - Google Patents

共溶媒処方物 Download PDF

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Publication number
JP4664499B2
JP4664499B2 JP2000542041A JP2000542041A JP4664499B2 JP 4664499 B2 JP4664499 B2 JP 4664499B2 JP 2000542041 A JP2000542041 A JP 2000542041A JP 2000542041 A JP2000542041 A JP 2000542041A JP 4664499 B2 JP4664499 B2 JP 4664499B2
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JP
Japan
Prior art keywords
ethanol
paracalcin
propylene glycol
composition
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2000542041A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002510652A (ja
JP2002510652A5 (enExample
Inventor
リー，ルクチユ
ペツク，エドワード・エイ
ロビンソン，ダニエル・エイチ
ステイーブンズ，デニス・エイ
ジヤンツイ，キヤシー
メイ，トーマス・ビイ
オーバデイア，ジヨン・ピー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22008769&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4664499(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JP2002510652A publication Critical patent/JP2002510652A/ja
Publication of JP2002510652A5 publication Critical patent/JP2002510652A5/ja
Application granted granted Critical
Publication of JP4664499B2 publication Critical patent/JP4664499B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000542041A 1998-04-08 1999-03-22 共溶媒処方物 Expired - Lifetime JP4664499B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/057,143 1998-04-08
US09/057,143 US6136799A (en) 1998-04-08 1998-04-08 Cosolvent formulations
PCT/US1999/006196 WO1999051271A2 (en) 1998-04-08 1999-03-22 Compositions comprising glycol derivatives and alcohols

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010207684A Division JP5548079B2 (ja) 1998-04-08 2010-09-16 共溶媒処方物

Publications (3)

Publication Number Publication Date
JP2002510652A JP2002510652A (ja) 2002-04-09
JP2002510652A5 JP2002510652A5 (enExample) 2010-11-18
JP4664499B2 true JP4664499B2 (ja) 2011-04-06

Family

ID=22008769

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2000542041A Expired - Lifetime JP4664499B2 (ja) 1998-04-08 1999-03-22 共溶媒処方物
JP2010207684A Expired - Lifetime JP5548079B2 (ja) 1998-04-08 2010-09-16 共溶媒処方物
JP2014016658A Expired - Lifetime JP5887368B2 (ja) 1998-04-08 2014-01-31 共溶媒処方物
JP2015204318A Pending JP2016053046A (ja) 1998-04-08 2015-10-16 共溶媒処方物

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2010207684A Expired - Lifetime JP5548079B2 (ja) 1998-04-08 2010-09-16 共溶媒処方物
JP2014016658A Expired - Lifetime JP5887368B2 (ja) 1998-04-08 2014-01-31 共溶媒処方物
JP2015204318A Pending JP2016053046A (ja) 1998-04-08 2015-10-16 共溶媒処方物

Country Status (11)

Country Link
US (2) US6136799A (enExample)
EP (1) EP1073467B1 (enExample)
JP (4) JP4664499B2 (enExample)
AT (1) ATE275974T1 (enExample)
AU (1) AU758989B2 (enExample)
CA (1) CA2326198C (enExample)
DE (1) DE69920201T2 (enExample)
DK (1) DK1073467T3 (enExample)
ES (1) ES2229693T3 (enExample)
PT (1) PT1073467E (enExample)
WO (1) WO1999051271A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011037860A (ja) * 1998-04-08 2011-02-24 Abbott Lab 共溶媒処方物

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
JP2004533807A (ja) * 2000-11-07 2004-11-11 ノース・キャロライナ・ステイト・ユニヴァーシティ プトレッシン−ｎ−メチルトランスフェラーゼプロモーター
EA008072B1 (ru) * 2001-12-03 2007-02-27 Новацея, Инк. Фармацевтические составы, содержащие соединения активного витамина d
DE60325459D1 (de) 2002-02-19 2009-02-05 Resolution Chemicals Ltd Auf lösungsmitteln basierende sterilisation von steroiden
US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
US20050026877A1 (en) * 2002-12-03 2005-02-03 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
US20060189586A1 (en) * 2003-06-11 2006-08-24 Cleland Jeffrey L Pharmaceutical compositions comprising active vitamin D compounds
US20050020546A1 (en) * 2003-06-11 2005-01-27 Novacea, Inc. Pharmaceutical compositions comprising active vitamin D compounds
US20050148557A1 (en) * 2003-07-29 2005-07-07 Jin Tian Use of Vitamin Ds to treat kidney disease
US20060009425A1 (en) * 2004-05-28 2006-01-12 Leticia Delgado-Herrera Oral formulations of paricalcitol
CN101223135A (zh) * 2005-07-18 2008-07-16 特瓦制药工业有限公司 帕立骨化醇的制备
US20070166187A1 (en) * 2006-01-18 2007-07-19 Song Jing F Stabilization of paricalcitol using chlorobutyl or chlorinated butyl stoppers
MX2008014418A (es) * 2006-05-15 2008-11-27 Wisconsin Alumni Res Found Administracion pulmonar de la 1 alfa, 25-dihidroxivitamina d3 y co-administracion de la homona paratiroidea o calcitonina.
US20100075933A1 (en) * 2008-07-28 2010-03-25 Sunita Vijay Shelke Injectable compositions of vitamin d compounds
US20110033529A1 (en) * 2009-08-06 2011-02-10 Durga Prasad Samantaray Oral pharmaceutical paricalcitol formulations
EP2545940A1 (de) * 2011-07-14 2013-01-16 hameln rds gmbh Parenterale Zusammensetzungen
MY172886A (en) 2012-06-29 2019-12-13 Wisconsin Alumni Res Found Use of 2-methylene-19-nor-(20s)-1?25-dihydroxyvitamin d3 to treat secondary hyperparathyroidism
ES2698403T3 (es) * 2012-12-27 2019-02-04 Pharmathen Sa Composición farmacéutica inyectable estable de agonista de receptor de vitamina D y proceso para su preparación
US9539264B2 (en) 2014-12-30 2017-01-10 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat secondary hyperparathyroidism in patients previously treated with calcimimetics
US10369161B2 (en) 2014-12-30 2019-08-06 Wisconsin Alumni Research Foundation Use of 2-methylene-19-NOR-(20S)-1-alpha,25-dihydroxyvitamin D3 to treat primary hyperparathyroidism
CN106265492B (zh) * 2015-06-04 2020-12-11 成都国为生物医药有限公司 一种含有帕立骨化醇的药物组合物及其制备方法
US10105375B2 (en) 2016-08-30 2018-10-23 Wisconsin Alumni Research Foundation Combination of low dose 2-methylene-19-nor-(20S)1α, 25-dihydroxyvitamin D3 and calcimimetics to treat secondary hyperparathyroidism

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198391A (en) * 1973-07-20 1980-04-15 R. P. Scherer Ltd. Pharmaceutical compositions
US4212886A (en) * 1978-11-01 1980-07-15 Survival Technology, Inc. Stabilized benactyzine hydrochloride
US4308264A (en) * 1981-01-28 1981-12-29 Abbott Laboratories Stabilized, dilute aqueous preparation of 1α,25-dihydroxycholecalciferol for neonatal administration
DE3316510A1 (de) * 1983-05-06 1984-11-08 Bayer Ag Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
US4588528A (en) * 1984-05-31 1986-05-13 Wisconsin Alumni Research Foundation 1,24-dihydroxy-Δ22 -vitamin D3 and process for preparing same
DE3437232A1 (de) * 1984-10-10 1986-04-17 Mack Chem Pharm Stabilisierte injektionsloesungen von piroxicam
US4594340A (en) * 1984-11-29 1986-06-10 Hoffmann-La Roche Inc. 25,26-dehydro-1α,24R-dihydroxycholecalciferol and 25,26-dehydro-1α,24S-dihydroxycholecalciferol and the epimeric mixture
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US5098899A (en) * 1989-03-06 1992-03-24 Trustees Of Boston University Method for therapeutically treating psoriatic arthritis using vitamin D analogues and metabolites
DK191889D0 (da) * 1989-04-20 1989-04-20 Bukh Meditec Kosmetisk middel
AU649057B2 (en) * 1990-08-24 1994-05-12 Wisconsin Alumni Research Foundation Methods and compositions containing vitamin D compounds for improvement of skin conditions
US5502224A (en) * 1991-06-04 1996-03-26 Marigen, S.A. Biotenside esters and phosphatides with vitamin-D and vitamin-E compounds
FR2677884B1 (fr) * 1991-06-20 1993-07-09 Oreal Composition pour freiner la chute des cheveux a base de pyrimidines n-oxyde trisubstitues ou leurs derives sulfoconjugues, nouveaux composes pyrimidines n-oxyde ou leurs derives sulfoconjugues.
PT100638B (pt) * 1991-06-28 1999-09-30 Univ Miami Metodo para evitar e tratar a alopecia induzida por quimioterapia
GB9201920D0 (en) * 1992-01-29 1992-03-18 Leo Pharm Prod Ltd Novel treatment i
JPH05246891A (ja) * 1992-03-09 1993-09-24 Kobayashi Seiyaku Kogyo Kk 安定な抗膵炎用注射液
KR960013798B1 (ko) * 1992-04-24 1996-10-10 재단법인 한국전자통신연구소 평면 도파로형 공간 스위치
WO1996036340A1 (en) * 1995-05-19 1996-11-21 Abbott Laboratories STABLE AQUEOUS FORMULATIONS OF 1α,25-DIHYDROXYCHOLECALCIFEROL FOR PARENTERAL ADMINISTRATION
US5597815A (en) * 1995-07-13 1997-01-28 Wisconsin Alumni Research Foundation Prevention of hyperphosphatemia in kidney disorder patients
ES2188932T3 (es) * 1996-04-04 2003-07-01 Cilag Ag Formulacion topica de vitamina d a base de liposomas.
DK0893121T3 (da) * 1997-06-27 2002-06-17 Akzo Nobel Nv Flydende oral medicinopløsning
CA2211949A1 (en) * 1997-07-21 1999-01-29 David Farley Johnson Nonaqueous compositions for parenteral administration
US6136799A (en) * 1998-04-08 2000-10-24 Abbott Laboratories Cosolvent formulations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011037860A (ja) * 1998-04-08 2011-02-24 Abbott Lab 共溶媒処方物

Also Published As

Publication number Publication date
JP2011037860A (ja) 2011-02-24
DE69920201D1 (de) 2004-10-21
JP2014129360A (ja) 2014-07-10
DE69920201T2 (de) 2005-09-29
WO1999051271A3 (en) 1999-11-18
WO1999051271A2 (en) 1999-10-14
US6361758B1 (en) 2002-03-26
ATE275974T1 (de) 2004-10-15
DK1073467T3 (da) 2005-01-03
JP5887368B2 (ja) 2016-03-16
AU758989B2 (en) 2003-04-03
CA2326198A1 (en) 1999-10-14
PT1073467E (pt) 2004-12-31
JP2002510652A (ja) 2002-04-09
JP2016053046A (ja) 2016-04-14
EP1073467B1 (en) 2004-09-15
US6136799A (en) 2000-10-24
JP5548079B2 (ja) 2014-07-16
EP1073467A2 (en) 2001-02-07
ES2229693T3 (es) 2005-04-16
CA2326198C (en) 2009-06-09
AU3359899A (en) 1999-10-25

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