JP4662556B2 - 治療薬デリバリー制御に関する相溶性ポリマーブレンド含有埋め込み又は挿入可能医療器具 - Google Patents
治療薬デリバリー制御に関する相溶性ポリマーブレンド含有埋め込み又は挿入可能医療器具 Download PDFInfo
- Publication number
- JP4662556B2 JP4662556B2 JP2006509193A JP2006509193A JP4662556B2 JP 4662556 B2 JP4662556 B2 JP 4662556B2 JP 2006509193 A JP2006509193 A JP 2006509193A JP 2006509193 A JP2006509193 A JP 2006509193A JP 4662556 B2 JP4662556 B2 JP 4662556B2
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- poly
- polymer
- therapeutic
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Prostheses (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/382,552 US8313759B2 (en) | 2003-03-06 | 2003-03-06 | Implantable or insertable medical devices containing miscible polymer blends for controlled delivery of a therapeutic agent |
| PCT/US2004/006853 WO2004080397A2 (en) | 2003-03-06 | 2004-03-05 | Implantable or insertable medical devices containing miscible polymer blends for controlled delivery of a therapeutic agent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006520673A JP2006520673A (ja) | 2006-09-14 |
| JP2006520673A5 JP2006520673A5 (enExample) | 2010-08-12 |
| JP4662556B2 true JP4662556B2 (ja) | 2011-03-30 |
Family
ID=32926917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509193A Expired - Fee Related JP4662556B2 (ja) | 2003-03-06 | 2004-03-05 | 治療薬デリバリー制御に関する相溶性ポリマーブレンド含有埋め込み又は挿入可能医療器具 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8313759B2 (enExample) |
| EP (1) | EP1599229A2 (enExample) |
| JP (1) | JP4662556B2 (enExample) |
| WO (1) | WO2004080397A2 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020188037A1 (en) * | 1999-04-15 | 2002-12-12 | Chudzik Stephen J. | Method and system for providing bioactive agent release coating |
| ATE466603T1 (de) | 1998-04-27 | 2010-05-15 | Surmodics Inc | Bioaktive wirkstoffe freisetzende beschichtungen |
| US7097850B2 (en) | 2002-06-18 | 2006-08-29 | Surmodics, Inc. | Bioactive agent release coating and controlled humidity method |
| US8211455B2 (en) * | 2002-06-19 | 2012-07-03 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled delivery of a therapeutic agent |
| US9114199B2 (en) * | 2003-07-31 | 2015-08-25 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices containing acrylic copolymer for controlled delivery of therapeutic agent |
| US7541048B2 (en) | 2004-04-06 | 2009-06-02 | Surmodics, Inc. | Coating compositions for bioactive agents |
| EP2594259A1 (en) | 2004-08-04 | 2013-05-22 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
| JP2006068378A (ja) * | 2004-09-03 | 2006-03-16 | Terumo Corp | 血管内留置物 |
| US7919110B2 (en) | 2005-01-25 | 2011-04-05 | Boston Scientific Scimed, Inc. | Medical device drug release regions containing non-covalently bound polymers |
| US7988987B2 (en) | 2005-01-25 | 2011-08-02 | Boston Scientific Scimed, Inc. | Medical devices containing crazed polymeric release regions for drug delivery |
| US9125968B2 (en) * | 2005-03-30 | 2015-09-08 | Boston Scientific Scimed, Inc. | Polymeric/ceramic composite materials for use in medical devices |
| US7517914B2 (en) | 2005-04-04 | 2009-04-14 | Boston Scientificscimed, Inc. | Controlled degradation materials for therapeutic agent delivery |
| US8008395B2 (en) * | 2005-09-27 | 2011-08-30 | Boston Scientific Scimed, Inc. | Organic-inorganic hybrid particle material and polymer compositions containing same |
| US8034874B2 (en) * | 2005-11-23 | 2011-10-11 | Boston Scientific Scimed, Inc. | Medical devices having polymeric regions that contain fluorocarbon-containing block copolymers |
| US7713637B2 (en) * | 2006-03-03 | 2010-05-11 | Advanced Cardiovascular Systems, Inc. | Coating containing PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid polymer |
| NZ588816A (en) | 2007-01-21 | 2011-11-25 | Hemoteq Ag | Medical device for the treatment of stenoses of corporal lumina and for the prevention of impending restenoses |
| US9192697B2 (en) | 2007-07-03 | 2015-11-24 | Hemoteq Ag | Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis |
| US7956100B2 (en) * | 2007-09-28 | 2011-06-07 | Abbott Cardiovascular Systems Inc. | Implantable medical devices fabricated from block copolymers |
| US8728528B2 (en) | 2007-12-20 | 2014-05-20 | Evonik Corporation | Process for preparing microparticles having a low residual solvent volume |
| US20090306769A1 (en) * | 2008-06-06 | 2009-12-10 | Boston Scientific Scimed, Inc. | Medical balloon made with hybrid polymer-ceramic material and method of making and using the same |
| US8128951B2 (en) | 2008-09-15 | 2012-03-06 | Cv Ingenuity Corp. | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US8257722B2 (en) | 2008-09-15 | 2012-09-04 | Cv Ingenuity Corp. | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US9198968B2 (en) * | 2008-09-15 | 2015-12-01 | The Spectranetics Corporation | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US8114429B2 (en) | 2008-09-15 | 2012-02-14 | Cv Ingenuity Corp. | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US8815971B2 (en) | 2008-12-22 | 2014-08-26 | ATRP Solutions, Inc. | Control over controlled radical polymerization processes |
| US8822610B2 (en) | 2008-12-22 | 2014-09-02 | ATRP Solutions, Inc. | Control over controlled radical polymerization processes |
| US9783628B2 (en) | 2009-04-23 | 2017-10-10 | ATRP Solutions, Inc. | Dual-mechanism thickening agents for hydraulic fracturing fluids |
| US8173750B2 (en) | 2009-04-23 | 2012-05-08 | ATRP Solutions, Inc. | Star macromolecules for personal and home care |
| WO2010123574A1 (en) | 2009-04-23 | 2010-10-28 | Atrp Solutions Inc | Star macromolecules for personal and home care |
| US10369256B2 (en) | 2009-07-10 | 2019-08-06 | Boston Scientific Scimed, Inc. | Use of nanocrystals for drug delivery from a balloon |
| EP2453938B1 (en) | 2009-07-17 | 2015-08-19 | Boston Scientific Scimed, Inc. | Nucleation of drug delivery balloons to provide improved crystal size and density |
| US20110097368A1 (en) * | 2009-10-23 | 2011-04-28 | Cao Group, Inc. | Treatment Varnish Compositions for Teeth Surfaces |
| US8889211B2 (en) | 2010-09-02 | 2014-11-18 | Boston Scientific Scimed, Inc. | Coating process for drug delivery balloons using heat-induced rewrap memory |
| WO2014121188A1 (en) | 2013-02-04 | 2014-08-07 | ATRP Solutions, Inc. | Salt-tolerant star macromolecules |
| US9587064B2 (en) | 2010-12-08 | 2017-03-07 | ATRP Solutions, Inc. | Salt-tolerant star macromolecules |
| US8669360B2 (en) | 2011-08-05 | 2014-03-11 | Boston Scientific Scimed, Inc. | Methods of converting amorphous drug substance into crystalline form |
| WO2013028208A1 (en) | 2011-08-25 | 2013-02-28 | Boston Scientific Scimed, Inc. | Medical device with crystalline drug coating |
| US9956385B2 (en) | 2012-06-28 | 2018-05-01 | The Spectranetics Corporation | Post-processing of a medical device to control morphology and mechanical properties |
| CA2882832C (en) | 2012-08-30 | 2021-08-24 | ATRP Solutions, Inc. | Dual mechanism thickening agents for hydraulic fracturing fluids |
| US20150025608A1 (en) | 2013-07-22 | 2015-01-22 | Cardiac Pacemakers, Inc. | Lubricious, biocompatible hydrophilic thermoset coating using interpenetrating hydrogel networks |
| US10525171B2 (en) | 2014-01-24 | 2020-01-07 | The Spectranetics Corporation | Coatings for medical devices |
| US10336848B2 (en) | 2014-07-03 | 2019-07-02 | Pilot Polymer Technologies, Inc. | Surfactant-compatible star macromolecules |
| EP3325084B1 (en) | 2015-07-25 | 2019-08-21 | Cardiac Pacemakers, Inc. | Medical electrical lead with biostable pvdf-based materials |
| CN110325224B (zh) | 2016-12-27 | 2023-01-31 | 波士顿科学国际有限公司 | 用于电纺的可降解支架 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US45706A (en) * | 1865-01-03 | Improvement in apparatus for aerating dough | ||
| US4847324A (en) * | 1988-04-25 | 1989-07-11 | Hydromer, Inc. | Hydrophilic polyvinylbutyral alloys |
| US4946899A (en) * | 1988-12-16 | 1990-08-07 | The University Of Akron | Thermoplastic elastomers of isobutylene and process of preparation |
| US5674192A (en) * | 1990-12-28 | 1997-10-07 | Boston Scientific Corporation | Drug delivery |
| US5304121A (en) * | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| US5258020A (en) * | 1990-09-14 | 1993-11-02 | Michael Froix | Method of using expandable polymeric stent with memory |
| US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5464650A (en) * | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
| US5994341A (en) * | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
| AU7476894A (en) * | 1993-07-29 | 1995-02-28 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Method of treating atherosclerosis or restenosis using microtubule stabilizing agent |
| US5502092A (en) * | 1994-02-18 | 1996-03-26 | Minnesota Mining And Manufacturing Company | Biocompatible porous matrix of bioabsorbable material |
| KR19990007865A (ko) * | 1995-04-19 | 1999-01-25 | 스피겔알렌제이 | 약물 방출용 피복 스텐트 |
| US6099562A (en) * | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| US5741331A (en) * | 1996-07-29 | 1998-04-21 | Corvita Corporation | Biostable elastomeric polymers having quaternary carbons |
| US5879697A (en) * | 1997-04-30 | 1999-03-09 | Schneider Usa Inc | Drug-releasing coatings for medical devices |
| WO1998056312A1 (en) | 1997-06-13 | 1998-12-17 | Scimed Life Systems, Inc. | Stents having multiple layers of biodegradable polymeric composition |
| US6110483A (en) * | 1997-06-23 | 2000-08-29 | Sts Biopolymers, Inc. | Adherent, flexible hydrogel and medicated coatings |
| JP2001514936A (ja) * | 1997-08-13 | 2001-09-18 | ボストン サイエンティフィック コーポレイション | 水不溶性薬剤の装填および放出 |
| US6306166B1 (en) | 1997-08-13 | 2001-10-23 | Scimed Life Systems, Inc. | Loading and release of water-insoluble drugs |
| US6997885B2 (en) * | 1998-04-08 | 2006-02-14 | Senorx, Inc. | Dilation devices and methods for removing tissue specimens |
| US6280411B1 (en) * | 1998-05-18 | 2001-08-28 | Scimed Life Systems, Inc. | Localized delivery of drug agents |
| US6335029B1 (en) | 1998-08-28 | 2002-01-01 | Scimed Life Systems, Inc. | Polymeric coatings for controlled delivery of active agents |
| US20020045706A1 (en) | 1998-09-22 | 2002-04-18 | Houston Michael R. | Biomedical molding materials from semi-solid precursors |
| US6443980B1 (en) * | 1999-03-22 | 2002-09-03 | Scimed Life Systems, Inc. | End sleeve coating for stent delivery |
| US6306419B1 (en) * | 2000-02-23 | 2001-10-23 | Aegis Biosciences, Llc | Medical uses of styrene sulfonate polymers |
| ES2329973T3 (es) * | 2000-11-30 | 2009-12-03 | Kabushiki Kaisha Kyoto Iryo Sekkei | Stent para vaso sanguineo y material para stent para vaso sanguineo. |
| US6545097B2 (en) * | 2000-12-12 | 2003-04-08 | Scimed Life Systems, Inc. | Drug delivery compositions and medical devices containing block copolymer |
| US7175873B1 (en) * | 2001-06-27 | 2007-02-13 | Advanced Cardiovascular Systems, Inc. | Rate limiting barriers for implantable devices and methods for fabrication thereof |
| SE523216C2 (sv) | 2001-07-27 | 2004-04-06 | Zoucas Kirurgkonsult Ab | Heparinstent |
| US20030236513A1 (en) | 2002-06-19 | 2003-12-25 | Scimed Life Systems, Inc. | Implantable or insertable medical devices for controlled delivery of a therapeutic agent |
| US7396539B1 (en) * | 2002-06-21 | 2008-07-08 | Advanced Cardiovascular Systems, Inc. | Stent coatings with engineered drug release rate |
| US20040033251A1 (en) * | 2002-08-13 | 2004-02-19 | Medtronic, Inc. | Active agent delivery system including a polyurethane, medical device, and method |
| DE60331552D1 (de) * | 2002-08-13 | 2010-04-15 | Medtronic Inc | Darreichungssysteme von wirkstoffen mit poly(ethylene-co(meth)akrylate, medizinische vorrichtung und verfahren |
-
2003
- 2003-03-06 US US10/382,552 patent/US8313759B2/en not_active Expired - Fee Related
-
2004
- 2004-03-05 EP EP04718104A patent/EP1599229A2/en not_active Withdrawn
- 2004-03-05 WO PCT/US2004/006853 patent/WO2004080397A2/en not_active Ceased
- 2004-03-05 JP JP2006509193A patent/JP4662556B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1599229A2 (en) | 2005-11-30 |
| WO2004080397A3 (en) | 2004-12-02 |
| JP2006520673A (ja) | 2006-09-14 |
| WO2004080397A2 (en) | 2004-09-23 |
| US8313759B2 (en) | 2012-11-20 |
| US20040175406A1 (en) | 2004-09-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4662556B2 (ja) | 治療薬デリバリー制御に関する相溶性ポリマーブレンド含有埋め込み又は挿入可能医療器具 | |
| JP5013862B2 (ja) | 治療薬を制御して送達する放射線架橋されたポリマーを含有する埋め込み可能又は挿入可能な医療装置 | |
| JP5270617B2 (ja) | ブロックコポリマを含む薬物送達構成体及び医療器具 | |
| JP5340913B2 (ja) | 生分解性ポリマー領域を有する医療デバイス | |
| EP1838361B1 (en) | Medical devices having vapor deposited nanoporous coatings for controlled therapeutic agent delivery | |
| JP5475950B2 (ja) | 制御された薬物送達および調節された生体適合性のための多孔質高分子領域を有する医療機器 | |
| JP5134013B2 (ja) | スチレンイソブチレン共重合体に基づくポリマー領域を有する医療デバイス | |
| JP5001005B2 (ja) | 治療薬デリバリー制御のためのグラフトコポリマー含有埋め込み可能又は挿入可能な医療器具 | |
| US7914805B2 (en) | Implantable or insertable medical devices containing radiation-treated polymer for improved delivery of therapeutic agent | |
| EP1786487B1 (en) | Medical devices having self-forming rate-controlling barrier for drug release | |
| US20090263445A1 (en) | Medical devices comprising spray dried microparticles | |
| CA2534332A1 (en) | Implantable or insertable medical devices containing acrylic copolymer for controlled delivery of therapeutic agent | |
| JP2007513643A5 (enExample) | ||
| EP2205292B1 (en) | Therapeutic agent-eluting medical devices having textured polymeric surfaces | |
| JP2008528120A (ja) | 薬物送達のための、ひび割れた高分子放出領域を含む医療機器 | |
| US7964209B2 (en) | Orienting polymer domains for controlled drug delivery | |
| JP2008532698A (ja) | 医療機器用の多環構造含有ポリマー含有薬剤放出領域 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060602 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070301 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20090629 |
|
| RD02 | Notification of acceptance of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7422 Effective date: 20090629 |
|
| RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20090710 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20091224 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20100323 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20100325 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20100330 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20100519 |
|
| A524 | Written submission of copy of amendment under article 19 pct |
Free format text: JAPANESE INTERMEDIATE CODE: A524 Effective date: 20100624 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20101210 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20101229 |
|
| R150 | Certificate of patent or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140114 Year of fee payment: 3 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |