JP4659041B2 - 血液尿素窒素(bun)センサ - Google Patents

血液尿素窒素(bun)センサ Download PDF

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JP4659041B2
JP4659041B2 JP2007530328A JP2007530328A JP4659041B2 JP 4659041 B2 JP4659041 B2 JP 4659041B2 JP 2007530328 A JP2007530328 A JP 2007530328A JP 2007530328 A JP2007530328 A JP 2007530328A JP 4659041 B2 JP4659041 B2 JP 4659041B2
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sensor
urease
urea
bun
layer
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Japanese (ja)
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JP2008511837A5 (https=
JP2008511837A (ja
Inventor
コリアー,ブルース,ジー.
ブラウワー,エリック
ウォン,アンジュリア
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アボット ポイント オブ ケア インコーポレイテッド
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/58Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving urea or urease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/005Enzyme electrodes involving specific analytes or enzymes

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP2007530328A 2004-09-02 2005-09-01 血液尿素窒素(bun)センサ Expired - Fee Related JP4659041B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60643604P 2004-09-02 2004-09-02
PCT/US2005/031048 WO2006028871A2 (en) 2004-09-02 2005-09-01 Blood urea nitrogen (bun) sensor

Publications (3)

Publication Number Publication Date
JP2008511837A JP2008511837A (ja) 2008-04-17
JP2008511837A5 JP2008511837A5 (https=) 2008-10-09
JP4659041B2 true JP4659041B2 (ja) 2011-03-30

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Family Applications (1)

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JP2007530328A Expired - Fee Related JP4659041B2 (ja) 2004-09-02 2005-09-01 血液尿素窒素(bun)センサ

Country Status (7)

Country Link
US (3) US7540948B2 (https=)
EP (1) EP1789796B1 (https=)
JP (1) JP4659041B2 (https=)
AT (1) ATE509118T1 (https=)
CA (1) CA2576272C (https=)
ES (1) ES2362790T3 (https=)
WO (1) WO2006028871A2 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214300B2 (en) * 2001-06-04 2007-05-08 Epocal Inc. Integrated electrokinetic devices and methods of manufacture
US6896778B2 (en) * 2001-06-04 2005-05-24 Epocal Inc. Electrode module
US7842234B2 (en) 2002-12-02 2010-11-30 Epocal Inc. Diagnostic devices incorporating fluidics and methods of manufacture
US7767068B2 (en) 2002-12-02 2010-08-03 Epocal Inc. Heterogeneous membrane electrodes
US7722817B2 (en) * 2003-08-28 2010-05-25 Epocal Inc. Lateral flow diagnostic devices with instrument controlled fluidics
EP1991113B1 (en) * 2006-02-27 2014-08-20 Edwards Lifesciences Corporation Flux limiting membrane for intravenous amperometric biosensor
US8268604B2 (en) * 2007-12-20 2012-09-18 Abbott Point Of Care Inc. Compositions for forming immobilized biological layers for sensing
US8241697B2 (en) * 2007-12-20 2012-08-14 Abbott Point Of Care Inc. Formation of immobilized biological layers for sensing
US8945936B2 (en) 2011-04-06 2015-02-03 Fresenius Medical Care Holdings, Inc. Measuring chemical properties of a sample fluid in dialysis systems
US8357293B1 (en) * 2011-07-11 2013-01-22 Gerhardt Van Drie Biological waste digester
US9670538B2 (en) 2011-08-05 2017-06-06 Ibis Biosciences, Inc. Nucleic acid sequencing by electrochemical detection
KR101772588B1 (ko) * 2011-08-22 2017-09-13 한국전자통신연구원 클리어 컴파운드 에폭시로 몰딩한 mit 소자 및 그것을 포함하는 화재 감지 장치
WO2013102093A1 (en) 2011-12-28 2013-07-04 Ibis Biosciences, Inc. Multiple- analyte assay device and system
CN105334250A (zh) * 2015-10-23 2016-02-17 吴国清 一种银/氯化银电极片及其制备工艺
DK4027137T3 (da) * 2015-12-18 2025-03-31 Radiometer Medical Aps Blandet ionofor ion-selektiv elektrode til forbedret detektion af urea i blod
US10753900B2 (en) 2016-06-30 2020-08-25 University Of Connecticut Real-time in situ sensing of water-related parameters using micro-electrode array
US10363245B2 (en) 2017-02-22 2019-07-30 The Board Of Regents Of The University Of Texas System Methods for treating CNS lesions
US11733197B2 (en) 2017-05-04 2023-08-22 Siemens Healthcare Diagnostics Inc. Biosensors produced from enzymes with reduced solubility and methods of production and use thereof
EP3537153A1 (en) * 2018-03-05 2019-09-11 Fuhrmann, Gerda Laura Means for the quantitative determination of an analyte concentration in a patient's urine sample
NO344627B1 (en) * 2018-04-30 2020-02-10 Sintef Tto As Hybrid polymer membrane
CN109946353A (zh) * 2018-11-08 2019-06-28 利多(香港)有限公司 电势型生物传感器和检测方法
CN109946352A (zh) * 2018-11-08 2019-06-28 利多(香港)有限公司 用于电势型生物传感器的反应试剂及其应用
JP7352497B2 (ja) * 2020-03-09 2023-09-28 日本特殊陶業株式会社 水質計測装置用の校正液、水質計測装置用の校正液入り容器、及び水質計測装置用の校正液を用いる校正方法。
CA3249940A1 (en) 2022-04-28 2023-11-02 Société des Produits Nestlé S.A. Methods of determining a health status of a cat based on one or more biomarkers, and methods of treating a mortality risk identified by the health status
CN121605196A (zh) * 2023-07-19 2026-03-03 美国西门子医学诊断股份有限公司 血液尿素氮(bun)传感器和感测生物样本中尿素氮的方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3116995A1 (de) * 1981-04-29 1982-11-25 Röhm GmbH, 6100 Darmstadt Latex zur immobilisierung von biologisch wirksamen substanzen
JPS61210939A (ja) * 1985-03-14 1986-09-19 Matsushita Electric Works Ltd 尿酸の測定法
JPS6264940A (ja) * 1985-09-18 1987-03-24 Fujitsu Ltd バイオセンサ−
JPS62144062A (ja) * 1985-12-18 1987-06-27 Fuji Electric Co Ltd 酵素センサ−
JPS636451A (ja) * 1986-06-27 1988-01-12 Terumo Corp 酵素センサ
US4713165A (en) * 1986-07-02 1987-12-15 Ilex Corporation Sensor having ion-selective electrodes
US4933048A (en) * 1988-02-16 1990-06-12 I-Stat Corporation Reference electrode, method of making and method of using same
US5096669A (en) * 1988-09-15 1992-03-17 I-Stat Corporation Disposable sensing device for real time fluid analysis
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5063081A (en) 1988-11-14 1991-11-05 I-Stat Corporation Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
US5081063A (en) * 1989-07-20 1992-01-14 Harris Corporation Method of making edge-connected integrated circuit structure
US5112455A (en) * 1990-07-20 1992-05-12 I Stat Corporation Method for analytically utilizing microfabricated sensors during wet-up
US5821399A (en) * 1993-07-16 1998-10-13 I-Stat Corporation Automatic test parameters compensation of a real time fluid analysis sensing device
AT401653B (de) * 1994-10-05 1996-11-25 Avl Verbrennungskraft Messtech Verfahren zur immobilisierung biologischer komponenten in einer polymermatrix sowie biosensoren unter verwendung derartiger immobilisate
WO1996040414A1 (en) * 1995-06-07 1996-12-19 Trachtenberg Michael C Enzyme systems for gas processing
US5858186A (en) * 1996-12-20 1999-01-12 The Regents Of The University Of California Urea biosensor for hemodialysis monitoring
US6030827A (en) * 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
JP3477511B2 (ja) * 1998-03-25 2003-12-10 国立身体障害者リハビリテーションセンター総長 金白金電極を用いたバイオセンサ
JP3901860B2 (ja) * 1998-11-02 2007-04-04 株式会社セロテック 複数の酵素を反応させる物質の定量方法及び酵素組成物
IT1307750B1 (it) * 1999-02-04 2001-11-19 Saicom S R L Biosensore amperometrico reattivo al ph.
US6291200B1 (en) * 1999-11-17 2001-09-18 Agentase, Llc Enzyme-containing polymeric sensors
JP4404433B2 (ja) * 2000-02-29 2010-01-27 株式会社テクノメデイカ 使い捨てbunセンサー及びその製造法

Also Published As

Publication number Publication date
ATE509118T1 (de) 2011-05-15
US8182663B2 (en) 2012-05-22
ES2362790T3 (es) 2011-07-13
US20090170140A1 (en) 2009-07-02
WO2006028871A3 (en) 2008-03-27
EP1789796B1 (en) 2011-05-11
CA2576272C (en) 2013-06-25
US20090159443A1 (en) 2009-06-25
CA2576272A1 (en) 2006-03-16
EP1789796A2 (en) 2007-05-30
US20060046275A1 (en) 2006-03-02
US7540948B2 (en) 2009-06-02
EP1789796A4 (en) 2008-11-12
WO2006028871A2 (en) 2006-03-16
JP2008511837A (ja) 2008-04-17
US8236517B2 (en) 2012-08-07
WO2006028871A9 (en) 2006-07-20

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