JP4603263B2 - 腫瘍の処置における抗血管形成療法のためのヒアルロン酸に基づくバイオマテリアル - Google Patents

腫瘍の処置における抗血管形成療法のためのヒアルロン酸に基づくバイオマテリアル Download PDF

Info

Publication number
JP4603263B2
JP4603263B2 JP2003557561A JP2003557561A JP4603263B2 JP 4603263 B2 JP4603263 B2 JP 4603263B2 JP 2003557561 A JP2003557561 A JP 2003557561A JP 2003557561 A JP2003557561 A JP 2003557561A JP 4603263 B2 JP4603263 B2 JP 4603263B2
Authority
JP
Japan
Prior art keywords
use according
hyaluronic acid
synthetic
group
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2003557561A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005524619A5 (https=
JP2005524619A (ja
Inventor
フーゼニッヒ，ノルベルト・エー
シュタルク，ハンス−ユルゲン
ヴィルハウク，ミハエル
パヴェシオ，アレッサンドラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia Farmaceutici SpA
Deutsches Krebsforschungszentrum DKFZ
Original Assignee
Fidia Farmaceutici SpA
Deutsches Krebsforschungszentrum DKFZ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Farmaceutici SpA, Deutsches Krebsforschungszentrum DKFZ filed Critical Fidia Farmaceutici SpA
Publication of JP2005524619A publication Critical patent/JP2005524619A/ja
Publication of JP2005524619A5 publication Critical patent/JP2005524619A5/ja
Application granted granted Critical
Publication of JP4603263B2 publication Critical patent/JP4603263B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2003557561A 2002-01-11 2003-01-07 腫瘍の処置における抗血管形成療法のためのヒアルロン酸に基づくバイオマテリアル Expired - Lifetime JP4603263B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002PD000003A ITPD20020003A1 (it) 2002-01-11 2002-01-11 Biomateriali a base di acido ialuronico come terapia anti-angiogenicanella cura dei tumori.
PCT/EP2003/000078 WO2003057203A2 (en) 2002-01-11 2003-01-07 Biomaterials based on hyaluronic acid for the anti-angiogenic therapy in the treatment of tumours

Publications (3)

Publication Number Publication Date
JP2005524619A JP2005524619A (ja) 2005-08-18
JP2005524619A5 JP2005524619A5 (https=) 2006-02-23
JP4603263B2 true JP4603263B2 (ja) 2010-12-22

Family

ID=11452500

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003557561A Expired - Lifetime JP4603263B2 (ja) 2002-01-11 2003-01-07 腫瘍の処置における抗血管形成療法のためのヒアルロン酸に基づくバイオマテリアル

Country Status (12)

Country Link
US (1) US7838510B2 (https=)
EP (1) EP1463541B1 (https=)
JP (1) JP4603263B2 (https=)
AT (1) ATE448809T1 (https=)
AU (1) AU2003201618B2 (https=)
CA (1) CA2472880C (https=)
DE (1) DE60330113D1 (https=)
DK (1) DK1463541T3 (https=)
ES (1) ES2334497T3 (https=)
IT (1) ITPD20020003A1 (https=)
PT (1) PT1463541E (https=)
WO (1) WO2003057203A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD20040312A1 (it) * 2004-12-15 2005-03-15 Fidia Advanced Biopolymers Srl Protesi e o supporto per la sostituzione, riparazione, rigenerazione del menisco

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6117A (ja) * 1984-06-11 1986-01-06 Seikagaku Kogyo Co Ltd ムコ多糖系癌転移抑制剤
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1219587B (it) * 1988-05-13 1990-05-18 Fidia Farmaceutici Polisaccaridi carbossiilici autoreticolati
US5143724A (en) 1990-07-09 1992-09-01 Biomatrix, Inc. Biocompatible viscoelastic gel slurries, their preparation and use
IT1254704B (it) * 1991-12-18 1995-10-09 Mini Ricerca Scient Tecnolog Tessuto non tessuto essenzialmente costituito da derivati dell'acido ialuronico
CA2094203A1 (en) * 1993-04-16 1994-10-17 Derek A. Willoughby Inhibition of angiogenesis
ITPD940054A1 (it) * 1994-03-23 1995-09-23 Fidia Advanced Biopolymers Srl Polisaccaridi solfatati
SI9620106B (sl) * 1995-08-29 2005-12-31 Fidia Advanced Biopolymers Srl Bioloski materiali za preprecevanje post-kirurskih adhezij, ki se sestojijo iz derivatov hialuronske kisline
DE69809892T2 (de) * 1997-04-04 2003-08-28 Fidia Advanced Biopolymers S.R.L., Brindisi N-sulfatierte hyaluronsäureverbindungen, ihre derivate und verfahren zu ihrer herstellung
IT1293484B1 (it) * 1997-06-11 1999-03-01 Fidia Advanced Biopolymers Srl Materiale biologico comprendente una efficiente coltura di cellule e una matrice tridimensionale biocompatibile e biodegradabile
US6872819B1 (en) * 1998-05-27 2005-03-29 Fidia Advanced Biopolymers S.R.L. Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells
ITPD980169A1 (it) * 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6472379B1 (en) 1999-03-15 2002-10-29 Trustees Of Boston University Angiogenesis inhibition
ATE328603T1 (de) 1999-03-26 2006-06-15 Univ Texas Modulatoren von polysacchariden und deren verwendungen
IT1317359B1 (it) 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Polisaccaridi percarbossilati, quali l'acido ialuronico, processo perla loro preparazione e loro impiego in campo farmaceutico e
IT1317358B1 (it) * 2000-08-31 2003-06-16 Fidia Advanced Biopolymers Srl Derivati cross-linkati dell'acido ialuronico.
WO2002041877A1 (en) * 2000-10-24 2002-05-30 Clear Solutions Biotech, Inc. Sodium hyaluronate microspheres

Also Published As

Publication number Publication date
ES2334497T3 (es) 2010-03-11
US20050037049A1 (en) 2005-02-17
ITPD20020003A1 (it) 2003-07-11
PT1463541E (pt) 2010-01-07
DK1463541T3 (da) 2010-03-08
AU2003201618A1 (en) 2003-07-24
AU2003201618B2 (en) 2008-11-06
US7838510B2 (en) 2010-11-23
EP1463541B1 (en) 2009-11-18
JP2005524619A (ja) 2005-08-18
ATE448809T1 (de) 2009-12-15
CA2472880A1 (en) 2003-07-17
CA2472880C (en) 2011-08-16
WO2003057203A2 (en) 2003-07-17
WO2003057203A3 (en) 2003-12-31
DE60330113D1 (de) 2009-12-31
EP1463541A2 (en) 2004-10-06

Similar Documents

Publication Publication Date Title
Luo et al. 3D printing of hydrogel scaffolds for future application in photothermal therapy of breast cancer and tissue repair
Zhu et al. Hyaluronic acid and polyethylene glycol hybrid hydrogel encapsulating nanogel with hemostasis and sustainable antibacterial property for wound healing
Xu et al. Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer
Cui et al. Hyaluronic acid hydrogel immobilized with RGD peptides for brain tissue engineering
Jay et al. Controlled delivery of VEGF via modulation of alginate microparticle ionic crosslinking
Chen et al. Zero-order controlled release of BMP2-derived peptide P24 from the chitosan scaffold by chemical grafting modification technique for promotion of osteogenesis in vitro and enhancement of bone repair in vivo
JP3618736B2 (ja) トロンビン由来ペプチドを使用した治療法
JP2007515949A5 (https=)
Yu et al. Enhancement of VEGF-mediated angiogenesis by 2-N, 6-O-sulfated chitosan-coated hierarchical PLGA scaffolds
Shalaby et al. Polymers of biological and biomedical significance
Abed et al. Influence of polysaccharide composition on the biocompatibility of pullulan/dextran‐based hydrogels
Moore et al. Impact of composite scaffold degradation rate on neural stem cell persistence in the glioblastoma surgical resection cavity
JP4820057B2 (ja) 薬物送達粒子及び製造方法
JP4603263B2 (ja) 腫瘍の処置における抗血管形成療法のためのヒアルロン酸に基づくバイオマテリアル
Yuan et al. Substrate-independent polymer coating with stimuli-responsive dexamethasone release for on-demand fibrosis inhibition
KR102279913B1 (ko) 이중가교성 화합물을 이용한 동맥류 색전술용 조성물 및 그 제조방법
Luo et al. Layer‐by‐layer assembly of chitosan and platelet monoclonal antibody to improve biocompatibility and release character of PLLA coated stent
Wang et al. Sequential Delivery of BMP2‐Derived Peptide P24 by Thiolated Chitosan/Calcium Carbonate Composite Microspheres Scaffolds for Bone Regeneration
Augustine et al. Control Release and Diffusion-Reaction Kinetics of Genipin-Eluting Fibers Using an in Vitro Aneurysm Flow Model
Sutrisno Preparation of Composite Scaffolds of Biodegradable Polymers and Black Phosphorus Nanosheets for Biomedical Applications
Jeslin et al. IPN Systems for Cancer Therapy
Carrêlo Smart Hydrogel-Based Injectable Systems for Breast Cancer Theranostics
Qi et al. Photothermal Hydrogel with Gel–Sol Transition for Programmed Antibacterial and Wound Healing
Yazdi et al. Lorna Westwood1, 2, Iain J. Nixon3, Elaine Emmerson2 and Anthony Callanan1
Ma et al. Decellularized liver matrix-based bioactive beads induce host-vasculature integrated embolization

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060104

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060104

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090825

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091118

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091126

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091207

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100216

RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20100427

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100430

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100604

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20100907

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20101001

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20131008

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Ref document number: 4603263

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term