JP2007515949A5 - - Google Patents

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Publication number
JP2007515949A5
JP2007515949A5 JP2006539632A JP2006539632A JP2007515949A5 JP 2007515949 A5 JP2007515949 A5 JP 2007515949A5 JP 2006539632 A JP2006539632 A JP 2006539632A JP 2006539632 A JP2006539632 A JP 2006539632A JP 2007515949 A5 JP2007515949 A5 JP 2007515949A5
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JP
Japan
Prior art keywords
tgf
antagonist
cancer
tumor
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2006539632A
Other languages
English (en)
Japanese (ja)
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JP2007515949A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/036651 external-priority patent/WO2005050200A2/en
Publication of JP2007515949A publication Critical patent/JP2007515949A/ja
Publication of JP2007515949A5 publication Critical patent/JP2007515949A5/ja
Withdrawn legal-status Critical Current

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JP2006539632A 2003-11-13 2004-11-04 スクリーニングアッセイ及び腫瘍治療の方法 Withdrawn JP2007515949A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52039803P 2003-11-13 2003-11-13
US55795104P 2004-03-31 2004-03-31
PCT/US2004/036651 WO2005050200A2 (en) 2003-11-13 2004-11-04 Screening assays and methods of tumor treatment

Publications (2)

Publication Number Publication Date
JP2007515949A JP2007515949A (ja) 2007-06-21
JP2007515949A5 true JP2007515949A5 (https=) 2007-12-20

Family

ID=34623132

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006539632A Withdrawn JP2007515949A (ja) 2003-11-13 2004-11-04 スクリーニングアッセイ及び腫瘍治療の方法

Country Status (13)

Country Link
US (1) US20060015952A1 (https=)
EP (1) EP1682890A2 (https=)
JP (1) JP2007515949A (https=)
KR (1) KR20060127409A (https=)
AR (1) AR046832A1 (https=)
AU (1) AU2004292180A1 (https=)
BR (1) BRPI0416305A (https=)
CA (1) CA2542215A1 (https=)
IL (1) IL174916A0 (https=)
NO (1) NO20062715L (https=)
RU (1) RU2006120483A (https=)
TW (1) TW200526957A (https=)
WO (1) WO2005050200A2 (https=)

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* Cited by examiner, † Cited by third party
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US7649013B2 (en) * 2003-11-26 2010-01-19 Arqule, Inc. Methods of protecting against radiation injury
EP1740615B1 (en) * 2004-03-31 2014-11-05 Genentech, Inc. Humanized anti-tgf-beta antibodies
US7412026B2 (en) * 2004-07-02 2008-08-12 The Board Of Regents Of The University Of Oklahoma Phase-contrast x-ray imaging systems and methods
US7853626B2 (en) 2006-09-29 2010-12-14 The Invention Science Fund I, Llc Computational systems for biomedical data
US10546652B2 (en) * 2006-09-29 2020-01-28 Gearbox Llc Computational systems for biomedical data
US20080082583A1 (en) * 2006-09-29 2008-04-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US20080082359A1 (en) * 2006-09-29 2008-04-03 Searete Llc, A Limited Liability Corporation Of State Of Delaware Computational systems for biomedical data
US20080082367A1 (en) * 2006-09-29 2008-04-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US10095836B2 (en) * 2006-09-29 2018-10-09 Gearbox Llc Computational systems for biomedical data
US10503872B2 (en) 2006-09-29 2019-12-10 Gearbox Llc Computational systems for biomedical data
US10068303B2 (en) 2006-09-29 2018-09-04 Gearbox Llc Computational systems for biomedical data
US8122073B2 (en) 2006-09-29 2012-02-21 The Invention Science Fund I Computational systems for biomedical data
US20080091730A1 (en) * 2006-09-29 2008-04-17 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US20080109484A1 (en) * 2006-09-29 2008-05-08 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US8491890B2 (en) * 2008-07-09 2013-07-23 Board Of Regents Of The University Of Nebraska Methods and compositions for inhibiting diseases of the central nervous system
BRPI0923155A2 (pt) 2008-12-05 2018-10-23 Abraxis Bioscience Llc scfcs de ligação a sparc
WO2010124276A2 (en) 2009-04-24 2010-10-28 Vanderbilt Universtiy Anti-tgf-beta induction of bone cell function and bone growth
US8476246B2 (en) * 2009-07-30 2013-07-02 Antisense Pharma Gmbh Combination of a chemotherapeutic agent and an inhibitor of the TGF-beta system
US20120208209A1 (en) * 2009-10-30 2012-08-16 Marina Ichetovkin Pcsk9 immunoassay
SI2835053T1 (sl) 2010-03-12 2016-09-30 Genzyme Corporation Kombinirana terapija za zdravljenje raka dojke
WO2013054320A1 (en) 2011-10-11 2013-04-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
US12156912B2 (en) 2012-05-18 2024-12-03 Board Of Regents Of The University Of Nebraska Methods and compositions for inhibiting diseases of the central nervous system
KR101479543B1 (ko) * 2013-03-15 2015-01-07 서강대학교산학협력단 Tfg-tec 융합 컨스트럭트를 이용한 종양 질환의 예방 또는 치료용 물질의 스크리닝 방법 및 이의 용도
US10550196B2 (en) 2014-04-27 2020-02-04 Famewave Ltd. Humanized antibodies against CEACAM1
US11427647B2 (en) 2014-04-27 2022-08-30 Famewave Ltd. Polynucleotides encoding humanized antibodies against CEACAM1
EP3234120B1 (en) 2014-12-15 2025-09-03 The Regents of the University of California Cytotoxic molecules responsive to intracellular ligands for selective t cell mediated killing
FI3240805T3 (fi) 2014-12-15 2025-02-17 Univ California Cd19- ja cd20-vasteellinen bispesifinen tai-veräjän kimeerinen antigeenireseptori
AU2016331081B2 (en) 2015-10-02 2021-04-29 Wake Forest University Health Sciences Methods and apparatus for modeling cancer metastasis in vitro
PL3368571T3 (pl) * 2015-10-30 2023-05-02 The Regents Of The University Of California Polipeptydy odpowiadające na transformujący czynnik wzrostu beta i sposoby ich zastosowania
US9758786B2 (en) 2016-02-09 2017-09-12 Autotelic, Llc Compositions and methods for treating pancreatic cancer
US12038432B2 (en) 2018-02-02 2024-07-16 Wake Forest University Health Sciences Organoids related to immunotherapy and methods of preparing and using the same
CN112566936B (zh) 2018-08-21 2024-07-12 阿尔伯特爱因斯坦医学院 针对人tim-3的单克隆抗体
WO2020124084A1 (en) * 2018-12-15 2020-06-18 The Brigham And Women's Hospital, Inc. Augmented digital microscopy for lesion analysis
CN111088227A (zh) * 2019-12-31 2020-05-01 广州航华生物医药科技有限公司 一种细胞分离培养液和t细胞分离培养的方法

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WO2000001410A1 (en) * 1998-07-06 2000-01-13 Beth Israel Deaconess Medical Center Methods of inhibiting proliferative diseases by inhibiting tgf-beta mediated angiogenesis
WO2001057061A1 (en) * 2000-02-04 2001-08-09 California Pacific Medical Center Research Institute Novel use of ribozymes to block gene expression
US20010046502A1 (en) * 2000-02-04 2001-11-29 The Board Of Trustees Of The University Of Illinois Animal model for testing immunotherapies of spontaneous metastatic disease
CA2298737A1 (en) * 2000-02-10 2001-08-10 Manikkam Suthanthiran 2167334tgf-.beta. antagonists to inhibit tumor cell formation or progression
US6632979B2 (en) * 2000-03-16 2003-10-14 Genentech, Inc. Rodent HER2 tumor model
US6767541B2 (en) * 2000-03-20 2004-07-27 The Regents Of The University Of California HER-2/neu overexpression abrogates growth inhibitory pathways
US20030125251A1 (en) * 2001-06-21 2003-07-03 Wakefield Lalage M. Transforming growth factor beta (TGF-beta) antagonist selectively neutralizes "pathological" TGF-beta

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