JP4511090B2 - Dnaプラスミドワクチン用アジュバンド及びその調製方法 - Google Patents
Dnaプラスミドワクチン用アジュバンド及びその調製方法 Download PDFInfo
- Publication number
- JP4511090B2 JP4511090B2 JP2001321828A JP2001321828A JP4511090B2 JP 4511090 B2 JP4511090 B2 JP 4511090B2 JP 2001321828 A JP2001321828 A JP 2001321828A JP 2001321828 A JP2001321828 A JP 2001321828A JP 4511090 B2 JP4511090 B2 JP 4511090B2
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- Prior art keywords
- pseudovirus
- cells
- plasmid
- mice
- virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20061—Methods of inactivation or attenuation
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cardiology (AREA)
- AIDS & HIV (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN01118003A CN1114690C (zh) | 2001-05-15 | 2001-05-15 | 乳头瘤假病毒及其制备方法 |
| CN01118003.X | 2001-05-15 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007124042A Division JP4472724B2 (ja) | 2001-05-15 | 2007-05-09 | パピロマウイルス偽ウイルス及びその調製方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003024058A JP2003024058A (ja) | 2003-01-28 |
| JP4511090B2 true JP4511090B2 (ja) | 2010-07-28 |
Family
ID=4662911
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001321828A Expired - Fee Related JP4511090B2 (ja) | 2001-05-15 | 2001-10-19 | Dnaプラスミドワクチン用アジュバンド及びその調製方法 |
| JP2007124042A Expired - Fee Related JP4472724B2 (ja) | 2001-05-15 | 2007-05-09 | パピロマウイルス偽ウイルス及びその調製方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007124042A Expired - Fee Related JP4472724B2 (ja) | 2001-05-15 | 2007-05-09 | パピロマウイルス偽ウイルス及びその調製方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US6878541B2 (enExample) |
| JP (2) | JP4511090B2 (enExample) |
| CN (1) | CN1114690C (enExample) |
| WO (1) | WO2002092796A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1114690C (zh) | 2001-05-15 | 2003-07-16 | 乔良 | 乳头瘤假病毒及其制备方法 |
| US20120164173A1 (en) * | 2001-05-15 | 2012-06-28 | Liang Qiao | Papilloma Pseudovirus and Preparation |
| EP1877087B1 (en) | 2005-04-15 | 2013-02-20 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Methods and compositions for producing an enhanced immune response to a human papillomavirus immunogen |
| CA2686990C (en) | 2007-05-08 | 2018-04-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Papillomavirus pseudoviruses for detection and therapy of tumors |
| ES2683352T3 (es) | 2009-04-13 | 2018-09-26 | Inserm - Institut National De La Santé Et De La Recherche Médicale | Partículas de HPV y usos de las mismas |
| WO2011039646A2 (en) | 2009-09-30 | 2011-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Papilloma virus -like particles for targeted gene delivery |
| WO2011053675A2 (en) | 2009-10-30 | 2011-05-05 | Cns Therapeutics, Inc. | Improved neurturin molecules |
| US9700639B2 (en) | 2012-02-07 | 2017-07-11 | Aura Biosciences, Inc. | Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells |
| CN104334196B (zh) | 2012-02-16 | 2018-04-10 | Atyr 医药公司 | 用于治疗自身免疫疾病和炎性疾病的组氨酰‑tRNA合成酶 |
| EP3517130B1 (en) | 2013-09-18 | 2022-03-30 | Aura Biosciences, Inc. | Method of producing photosensitive molecules |
| JP2018532801A (ja) | 2015-10-30 | 2018-11-08 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 標的化がん療法 |
| CN108602872A (zh) | 2015-10-30 | 2018-09-28 | 艾丽塔生物治疗剂公司 | 用于治疗癌症的组合物和方法 |
| CN108472365A (zh) | 2015-10-30 | 2018-08-31 | 艾丽塔生物治疗剂公司 | 用于肿瘤转导的组合物和方法 |
| US10751398B2 (en) * | 2016-10-07 | 2020-08-25 | Loyola University Chicago | Inflammasome activators and methods of use to treat tumors |
| US11285203B2 (en) | 2017-06-23 | 2022-03-29 | Verimmune Inc. | Chimeric virus-like particles and uses thereof as antigen-specific redirectors of immune responses |
| CN120392995A (zh) | 2017-11-06 | 2025-08-01 | 美利坚合众国,由健康及人类服务部部长代表 | 利用预先存在的微生物免疫的癌症治疗 |
| JP2021502822A (ja) | 2017-11-14 | 2021-02-04 | フラウンホファー ゲセルシャフト ツール フェールデルンク ダー アンゲヴァンテン フォルシュンク エー.ファオ. | in vitro及びin vivoでの遺伝子送達のための非ヒトパピローマウイルス |
| CA3125184A1 (en) | 2018-12-27 | 2020-07-02 | Verimmune Inc. | Conjugated virus-like particles and uses thereof as anti-tumor immune redirectors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19526752C2 (de) * | 1995-07-21 | 1997-08-07 | Lutz Prof Dr Gissmann | Hocheffiziente Bildung von Papillomavirusähnlichen Partikeln |
| FR2749323B1 (fr) * | 1996-06-04 | 1998-07-10 | Pasteur Merieux Serums Vacc | Pseudo-particules virales utiles en tant que vecteur de delivrance d'acide nucleique |
| AU732125B2 (en) * | 1996-07-17 | 2001-04-12 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Infectious papillomavirus pseudoviral particles |
| EP1015561B1 (en) * | 1997-09-05 | 2006-07-19 | Medimmune, Inc. | In vitro method for disassembly/reassembly of papillomavirus virus-like particles (vlps) |
| GB9806666D0 (en) * | 1998-03-27 | 1998-05-27 | Stanley Margaret | Antigen preparation and use |
| CN1241636A (zh) * | 1999-07-05 | 2000-01-19 | 第一军医大学珠江医院 | 抗hpv16e6核酶质粒及其在人乳头瘤病毒与肿瘤治疗中的应用 |
| GB0007231D0 (en) * | 2000-03-24 | 2000-05-17 | Chiron Spa | Modified rna for gene delivery |
| CN1114690C (zh) * | 2001-05-15 | 2003-07-16 | 乔良 | 乳头瘤假病毒及其制备方法 |
-
2001
- 2001-05-15 CN CN01118003A patent/CN1114690C/zh not_active Expired - Fee Related
- 2001-10-19 JP JP2001321828A patent/JP4511090B2/ja not_active Expired - Fee Related
-
2002
- 2002-03-22 WO PCT/CN2002/000187 patent/WO2002092796A1/zh not_active Ceased
- 2002-11-14 US US10/294,087 patent/US6878541B2/en not_active Expired - Lifetime
-
2005
- 2005-02-17 US US11/060,034 patent/US7205126B2/en not_active Expired - Fee Related
-
2007
- 2007-04-09 US US11/784,626 patent/US8129144B2/en not_active Expired - Fee Related
- 2007-05-09 JP JP2007124042A patent/JP4472724B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007211026A (ja) | 2007-08-23 |
| US20050142115A1 (en) | 2005-06-30 |
| US20100255027A1 (en) | 2010-10-07 |
| US8129144B2 (en) | 2012-03-06 |
| US6878541B2 (en) | 2005-04-12 |
| US7205126B2 (en) | 2007-04-17 |
| JP2003024058A (ja) | 2003-01-28 |
| CN1114690C (zh) | 2003-07-16 |
| WO2002092796A1 (en) | 2002-11-21 |
| JP4472724B2 (ja) | 2010-06-02 |
| US20030129728A1 (en) | 2003-07-10 |
| CN1333338A (zh) | 2002-01-30 |
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