JP4503180B2 - 視覚および記憶障害のための組成物および使用法 - Google Patents
視覚および記憶障害のための組成物および使用法 Download PDFInfo
- Publication number
- JP4503180B2 JP4503180B2 JP2000564611A JP2000564611A JP4503180B2 JP 4503180 B2 JP4503180 B2 JP 4503180B2 JP 2000564611 A JP2000564611 A JP 2000564611A JP 2000564611 A JP2000564611 A JP 2000564611A JP 4503180 B2 JP4503180 B2 JP 4503180B2
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- JP
- Japan
- Prior art keywords
- linear
- alkenyl
- alkyl
- group
- branched
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 CCC(C)(C)C(C(*(CCC1)[C@@]1C(CC)=O)=O)=O Chemical compound CCC(C)(C)C(C(*(CCC1)[C@@]1C(CC)=O)=O)=O 0.000 description 4
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13442298A | 1998-08-14 | 1998-08-14 | |
US09/134,422 | 1998-08-14 | ||
PCT/US1999/018241 WO2000009108A2 (fr) | 1998-08-14 | 1999-08-12 | Compositions destinees a des troubles de la vision et de la memoire, et leurs utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2002522484A JP2002522484A (ja) | 2002-07-23 |
JP4503180B2 true JP4503180B2 (ja) | 2010-07-14 |
Family
ID=22463332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000564611A Expired - Fee Related JP4503180B2 (ja) | 1998-08-14 | 1999-08-12 | 視覚および記憶障害のための組成物および使用法 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1105112A2 (fr) |
JP (1) | JP4503180B2 (fr) |
AU (1) | AU5555699A (fr) |
CA (1) | CA2335815A1 (fr) |
WO (1) | WO2000009108A2 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6218424B1 (en) * | 1996-09-25 | 2001-04-17 | Gpi Nil Holdings, Inc. | Heterocyclic ketone and thioester compounds and uses |
CA2379993A1 (fr) * | 1999-07-30 | 2001-02-08 | Vertex Pharmaceuticals Incorporated | Derives d'amines acycliques et cycliques |
AR034103A1 (es) * | 1999-11-12 | 2004-02-04 | Alcon Inc | Composicion farmaceutica que comprende ligandos de neurofilina para el tratamiento de condiciones oculares |
CN1240691C (zh) * | 2001-12-06 | 2006-02-08 | 中国人民解放军军事医学科学院毒物药物研究所 | 取代五元氮杂环类化合物及其预防和治疗神经退行性疾病的用途 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5192773A (en) * | 1990-07-02 | 1993-03-09 | Vertex Pharmaceuticals, Inc. | Immunosuppressive compounds |
WO1992019593A1 (fr) * | 1991-05-09 | 1992-11-12 | Vertex Pharmaceuticals Incorporated | Nouveaux composes immunosuppresseurs |
US5696135A (en) * | 1995-06-07 | 1997-12-09 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth |
US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
US6037370A (en) * | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
US5801197A (en) * | 1995-10-31 | 1998-09-01 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
WO1997031020A1 (fr) * | 1996-02-22 | 1997-08-28 | The General Hospital Corporation | PROCEDES ET COMPOSITIONS POUR AMELIORER LA REPONSE CELLULAIRE AUX LIGANDS DE TGF-$g(b) |
US5801187A (en) * | 1996-09-25 | 1998-09-01 | Gpi-Nil Holdings, Inc. | Heterocyclic esters and amides |
US5786378A (en) * | 1996-09-25 | 1998-07-28 | Gpi Nil Holdings, Inc. | Heterocyclic thioesters |
US5846979A (en) * | 1997-02-28 | 1998-12-08 | Gpi Nil Holdings, Inc. | N-oxides of heterocyclic esters, amides, thioesters, and ketones |
WO1998048784A2 (fr) * | 1997-04-28 | 1998-11-05 | The University Of British Columbia | Methodes et composition de modulation de l'amyloidose |
US6121280A (en) * | 1998-03-24 | 2000-09-19 | Pfizer Inc. | Azabicyclic rotomase inhibitors |
-
1999
- 1999-08-12 AU AU55556/99A patent/AU5555699A/en not_active Abandoned
- 1999-08-12 EP EP99942108A patent/EP1105112A2/fr not_active Withdrawn
- 1999-08-12 JP JP2000564611A patent/JP4503180B2/ja not_active Expired - Fee Related
- 1999-08-12 WO PCT/US1999/018241 patent/WO2000009108A2/fr not_active Application Discontinuation
- 1999-08-12 CA CA002335815A patent/CA2335815A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2000009108A3 (fr) | 2000-05-18 |
CA2335815A1 (fr) | 2000-02-24 |
EP1105112A2 (fr) | 2001-06-13 |
AU5555699A (en) | 2000-03-06 |
JP2002522484A (ja) | 2002-07-23 |
WO2000009108A2 (fr) | 2000-02-24 |
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