JP4502814B2 - 細胞性免疫応答を測定する診断アッセイ法 - Google Patents

細胞性免疫応答を測定する診断アッセイ法 Download PDF

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JP4502814B2
JP4502814B2 JP2004548932A JP2004548932A JP4502814B2 JP 4502814 B2 JP4502814 B2 JP 4502814B2 JP 2004548932 A JP2004548932 A JP 2004548932A JP 2004548932 A JP2004548932 A JP 2004548932A JP 4502814 B2 JP4502814 B2 JP 4502814B2
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antigen
immune effector
immune
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cells
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JP2006506609A5 (enExample
JP2006506609A (ja
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ジェイムス スチュアート ロゼル
スティーブン ポール． ワイルド
アンゲラ コスグリフ
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CELLESTIS PTY LTD
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
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  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Holo Graphy (AREA)
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JP2004548932A 2002-11-08 2003-11-06 細胞性免疫応答を測定する診断アッセイ法 Expired - Lifetime JP4502814B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2002952548A AU2002952548A0 (en) 2002-11-08 2002-11-08 Diagnostic assay
PCT/AU2003/001464 WO2004042396A1 (en) 2002-11-08 2003-11-06 Diagnostic assay for measuring a cell mediated immune response

Publications (3)

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JP2006506609A JP2006506609A (ja) 2006-02-23
JP2006506609A5 JP2006506609A5 (enExample) 2010-04-15
JP4502814B2 true JP4502814B2 (ja) 2010-07-14

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US (1) US7608392B2 (enExample)
EP (1) EP1561106B1 (enExample)
JP (1) JP4502814B2 (enExample)
AT (1) ATE429640T1 (enExample)
AU (1) AU2002952548A0 (enExample)
CA (1) CA2504829C (enExample)
DE (1) DE60327354D1 (enExample)
WO (1) WO2004042396A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12398176B2 (en) 2018-08-27 2025-08-26 Regeneron Pharmaceuticals, Inc. Use of Raman spectroscopy in downstream purification

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050164168A1 (en) * 2003-03-28 2005-07-28 Cullum Malford E. Method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines
JP2006189338A (ja) * 2005-01-06 2006-07-20 Sekisui Chem Co Ltd 炎症性腸疾患の治療前効果予測方法並びに治療効果の判定方法
GB0616238D0 (en) 2006-08-15 2006-09-27 Inst Animal Health Ltd Diagnostic Test
JP5805368B2 (ja) * 2006-09-05 2015-11-04 ステイテンス・セラム・インスティテュート Ｉｐ−１０に基づく免疫学的モニタリング
WO2008147426A2 (en) * 2006-10-04 2008-12-04 The Brigham And Women's Hospital, Inc. Methods and compositions for immunomodulation
AU2008229636B2 (en) * 2007-03-16 2014-08-14 Qiagen Sciences Llc A cell-mediated immune response assay and kits therefor
US20100196327A1 (en) * 2007-04-11 2010-08-05 Cell Science Systems Methods for diagnosing biological samples containing stem cells
US20090062237A1 (en) * 2007-06-15 2009-03-05 Mayo Foundation For Medical Education And Research Evaluating immune competence
US20100221755A1 (en) * 2007-06-15 2010-09-02 University Of Rochester Use of antibody secreting cell elispot to assess antibody responses following antigen exposure
EP3431987A1 (en) * 2008-07-25 2019-01-23 Cellestis Limited A diagnostic method
MX346450B (es) 2008-11-30 2017-03-17 Immusant Inc * Composiciones y métodos para el tratamiento de la enfermedad celíaca.
WO2010144800A1 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Methods and compositions for promoting a cell-mediated immune response
WO2010144794A1 (en) 2009-06-12 2010-12-16 Vaccine Technologies, Incorporated Baculovirus-expressed fusion polypeptide vaccines with enhanced immunogenicity and uses thereof
AU2010336016B2 (en) * 2009-12-23 2017-07-27 Qiagen Sciences Llc An assay for measuring cell-mediated immunoresponsiveness
US8771967B2 (en) 2010-11-16 2014-07-08 The Board Of Trustees Of The Leland Stanford Junior University Immunomodulation of functional T cell assays for diagnosis of infectious or autoimmune disorders
WO2012145786A1 (en) * 2011-04-29 2012-11-01 Cellestis Limited An assay of cell mediated immune responsiveness
US9678071B2 (en) 2012-01-12 2017-06-13 Mayo Foundation For Medical Education And Research Detecting latent tuberculosis infections
WO2013139972A1 (en) * 2012-03-23 2013-09-26 Laboratorios Del Dr. Esteve, S.A. Method for monitoring hiv specific t cell responses
CN102707052B (zh) * 2012-05-11 2015-03-11 中国农业科学院北京畜牧兽医研究所 含重组蛋白混合物的牛结核病检测试剂
ES3031233T3 (en) 2012-12-28 2025-07-07 Qiagen Sciences Llc A cell mediated immune response assay
JP6494527B2 (ja) 2013-02-07 2019-04-03 ザ チルドレンズ メディカル センター コーポレーション 肺炎球菌のコロニー形成および／または疾患からの保護を提供するタンパク質抗原
US10401360B2 (en) 2013-04-29 2019-09-03 Mayo Foundation For Medical Education And Research Flow cytometry assay methods
AU2014318889B2 (en) 2013-09-10 2020-02-20 Immusant, Inc. Dosage of a gluten peptide composition
CN103604933A (zh) * 2013-11-27 2014-02-26 华中科技大学同济医学院附属同济医院 基于抗原特异性TNF-α-ELISA检测活动性结核病的试剂盒及其应用
WO2016054038A1 (en) 2014-09-29 2016-04-07 Immusant, Inc. Use of hla genetic status to assess or select treatment of celiac disease
KR20170071507A (ko) 2014-10-23 2017-06-23 퀴아젠 사이언시스, 엘엘씨 펩티드 조성물 및 그의 용도
US10654923B2 (en) 2015-12-28 2020-05-19 Mayo Foundation For Medical Education And Research Methods for treating medical conditions by anti-type 2 therapy
KR20170110297A (ko) * 2016-03-23 2017-10-11 온틀협동조합 천연물 소재의 면역증강 검사법 및 상기 검사법을 활용한 맞춤형 식단 제공방법
KR101777256B1 (ko) 2016-07-07 2017-09-12 대한민국(농림축산식품부 농림축산검역본부장) T 세포의 병원체 감염 세포 독성능 평가 방법
KR101777252B1 (ko) 2016-07-07 2017-09-12 대한민국(농림축산식품부 농림축산검역본부장) T 세포의 prrsv 증식 억제능 평가 방법
WO2018111536A1 (en) 2016-12-14 2018-06-21 Becton, Dickinson And Company Methods and compositions for obtaining a tuberculosis assessment in a subject
WO2020014703A1 (en) * 2018-07-13 2020-01-16 Excision Biotherapeutics, Inc. Detection of bacterial proteins/immunoglobulins for gene editing therapy
US20230242591A1 (en) * 2020-02-14 2023-08-03 Epivax, Inc. Regulatory t cell epitopes and detolerized sars-cov-2 antigens
EP4179328A2 (en) * 2020-07-10 2023-05-17 Covid Diagnostics Ltd. Compositions, methods, and systems for detecting immune response
CN113466000A (zh) * 2021-05-12 2021-10-01 广州医科大学附属肿瘤医院 基于多维度纯化富集技术的恶性胸水检测方法
EP4537103A1 (en) * 2022-06-09 2025-04-16 The Regents of University of California Lymphocyte stimulation assay to quantify immune responses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018653A (en) 1971-10-29 1977-04-19 U.S. Packaging Corporation Instrument for the detection of Neisseria gonorrhoeae without culture
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4424279A (en) 1982-08-12 1984-01-03 Quidel Rapid plunger immunoassay method and apparatus
CA1299099C (en) * 1986-03-06 1992-04-21 Paul Richard Wood In vitro assay for detecting cell-mediated immune responses
FR2615622B1 (fr) * 1987-05-19 1994-05-06 Ire Medgenix Sa Dosage plasmatique de monokines
US5693500A (en) * 1988-03-31 1997-12-02 Commonwealth Scientific And Industrial Research Organisation Diagnosis of Mycobacterium bovis infection
FR2645878B1 (fr) * 1989-04-17 1994-02-25 Institut Nal Sante Recherc Medic Sequences nucleotidiques d'actinomycetales, applications a la synthese ou a la detection d'acides nucleiques, produits d'expression de ces sequences et application en tant que compositions immunogenes
US6410252B1 (en) * 1995-12-22 2002-06-25 Case Western Reserve University Methods for measuring T cell cytokines
US5885529A (en) * 1996-06-28 1999-03-23 Dpc Cirrus, Inc. Automated immunoassay analyzer
DE19835721A1 (de) * 1998-08-07 2000-02-10 Edi Experimentelle & Diagnosti Verfahren zur Bestimmung der Immunabwehr des Blutes sowie Testkit hierfür und Verwendung eines geeigneten Spritzenzylinders

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12398176B2 (en) 2018-08-27 2025-08-26 Regeneron Pharmaceuticals, Inc. Use of Raman spectroscopy in downstream purification

Also Published As

Publication number Publication date
US7608392B2 (en) 2009-10-27
EP1561106B1 (en) 2009-04-22
ATE429640T1 (de) 2009-05-15
AU2002952548A0 (en) 2002-11-21
WO2004042396A1 (en) 2004-05-21
EP1561106A4 (en) 2006-12-27
US20050014205A1 (en) 2005-01-20
EP1561106A1 (en) 2005-08-10
JP2006506609A (ja) 2006-02-23
CA2504829C (en) 2013-01-22
DE60327354D1 (de) 2009-06-04
CA2504829A1 (en) 2004-05-21

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