JP4489351B2 - ヒト免疫不全ウイルスに対するモノクローナル抗体およびその用途 - Google Patents
ヒト免疫不全ウイルスに対するモノクローナル抗体およびその用途 Download PDFInfo
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
- C07K14/155—Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
- C07K14/16—HIV-1 ; HIV-2
- C07K14/161—HIV-1 ; HIV-2 gag-pol, e.g. p55, p24/25, p17/18, p7, p6, p66/68, p51/52, p31/34, p32, p40
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/731,126 US6818392B2 (en) | 2000-12-06 | 2000-12-06 | Monoclonal antibodies to human immunodeficiency virus and uses thereof |
| PCT/US2001/043179 WO2002064615A2 (en) | 2000-12-06 | 2001-12-05 | Monoclonal antibodies to human immunodeficiency virus and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004536568A JP2004536568A (ja) | 2004-12-09 |
| JP2004536568A5 JP2004536568A5 (enExample) | 2009-01-15 |
| JP4489351B2 true JP4489351B2 (ja) | 2010-06-23 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002564544A Expired - Lifetime JP4489351B2 (ja) | 2000-12-06 | 2001-12-05 | ヒト免疫不全ウイルスに対するモノクローナル抗体およびその用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (10) | US6818392B2 (enExample) |
| EP (2) | EP1341820A2 (enExample) |
| JP (1) | JP4489351B2 (enExample) |
| CA (1) | CA2431321C (enExample) |
| ES (1) | ES2619370T3 (enExample) |
| WO (1) | WO2002064615A2 (enExample) |
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| US6818392B2 (en) * | 2000-12-06 | 2004-11-16 | Abbott Laboratories | Monoclonal antibodies to human immunodeficiency virus and uses thereof |
| US20040063220A1 (en) * | 2002-02-27 | 2004-04-01 | Lebrun Stewart J. | Substrate chemistry for protein immobilization on a rigid support |
| US20050054118A1 (en) * | 2002-02-27 | 2005-03-10 | Lebrun Stewart J. | High throughput screening method |
| US8101431B2 (en) | 2004-02-27 | 2012-01-24 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems |
| US8105849B2 (en) | 2004-02-27 | 2012-01-31 | Board Of Regents, The University Of Texas System | Integration of fluids and reagents into self-contained cartridges containing sensor elements |
| US8377398B2 (en) | 2005-05-31 | 2013-02-19 | The Board Of Regents Of The University Of Texas System | Methods and compositions related to determination and use of white blood cell counts |
| WO2008059553A1 (en) * | 2006-11-13 | 2008-05-22 | Masami Moriyama | Method for detecting hiv-1 without being affected by anti-mouse protein antibody existing in human and kit to be used for the same |
| FI120376B (fi) * | 2007-01-17 | 2009-09-30 | Next Biomed Technologies Nbt O | Menetelmä biomuokatun, korkean affiniteetin polypeptidin valmistamiseksi |
| US20090181359A1 (en) | 2007-10-25 | 2009-07-16 | Lou Sheng C | Method of performing ultra-sensitive immunoassays |
| US8222048B2 (en) | 2007-11-05 | 2012-07-17 | Abbott Laboratories | Automated analyzer for clinical laboratory |
| CN102076355B (zh) | 2008-04-29 | 2014-05-07 | Abbvie公司 | 双重可变结构域免疫球蛋白及其用途 |
| AU2009256246B2 (en) | 2008-06-03 | 2013-07-18 | Abbvie Inc. | Dual variable domain immunoglobulins and uses thereof |
| SG191639A1 (en) | 2008-06-03 | 2013-07-31 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| AU2009268585C1 (en) | 2008-07-08 | 2014-10-02 | Abbvie Inc. | Prostaglandin E2 dual variable domain immunoglobulins and uses thereof |
| US20110236373A1 (en) * | 2008-09-25 | 2011-09-29 | Georgia Tomaras | Method of detecting antibodies and antibody-hiv virion complexes |
| US8916154B2 (en) * | 2009-04-27 | 2014-12-23 | Abbott Laboratories | Antibodies against delta-5 desaturase and uses thereof |
| JP2012525441A (ja) * | 2009-05-01 | 2012-10-22 | アボット・ラボラトリーズ | 二重可変ドメイン免疫グロブリンおよびこの使用 |
| US20100297778A1 (en) * | 2009-05-20 | 2010-11-25 | Abbott Laboratories | Conjugate Having Cleavable Linking Agent |
| DK2478364T3 (da) | 2009-09-15 | 2017-11-13 | Gemini Res Limited | Påvisning af autoantistoffer mod nukleære antigener |
| UY32948A (es) * | 2009-10-15 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| CA2793959C (en) | 2010-03-25 | 2019-06-04 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| TW201206473A (en) | 2010-08-03 | 2012-02-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| CA2809363A1 (en) * | 2010-08-24 | 2012-03-01 | Abbott Laboratories | Hiv core protein specific antibodies and uses thereof |
| CN103260639A (zh) | 2010-08-26 | 2013-08-21 | Abbvie公司 | 双重可变结构域免疫球蛋白及其用途 |
| PT2691530T (pt) | 2011-06-10 | 2018-05-10 | Univ Oregon Health & Science | Glicoproteínas e vectores recombinantes cmv |
| US20130064811A1 (en) * | 2011-09-09 | 2013-03-14 | International Business Machines Corporation | Methods to Enhance Cancer Treatment |
| EP2568289A3 (en) | 2011-09-12 | 2013-04-03 | International AIDS Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| EP2586461A1 (en) | 2011-10-27 | 2013-05-01 | Christopher L. Parks | Viral particles derived from an enveloped virus |
| WO2013102042A2 (en) | 2011-12-30 | 2013-07-04 | Abbvie Inc. | Dual specific binding proteins directed against il-13 and/or il-17 |
| ES2631608T3 (es) | 2012-06-27 | 2017-09-01 | International Aids Vaccine Initiative | Variante de la glicoproteína Env del VIH-1 |
| HK1212359A1 (en) | 2012-11-01 | 2016-06-10 | Abbvie Inc. | Anti-vegf/dll4 dual variable domain immunoglobulins and uses thereof |
| JP2016522793A (ja) | 2013-03-15 | 2016-08-04 | アッヴィ・インコーポレイテッド | ＩＬ−１βおよび／またはＩＬ−１７に対して指向された二重特異的結合タンパク質 |
| US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
| EP2873423B1 (en) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
| US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白 |
| CN105929157A (zh) * | 2016-05-25 | 2016-09-07 | 苏州新波生物技术有限公司 | 一种联合检测hiv抗原抗体的诊断试剂盒及其制备方法 |
| WO2018133038A1 (zh) * | 2017-01-20 | 2018-07-26 | 深圳市新产业生物医学工程股份有限公司 | 标记复合物及其制备方法、试剂盒、应用和检测系统 |
| IL280880B2 (en) | 2018-08-27 | 2025-04-01 | Regeneron Pharma | Using Raman Spectroscopy in Downstream Purification |
| CN115812078A (zh) * | 2020-07-13 | 2023-03-17 | 盖立复诊断解决方案公司 | 抗人类免疫缺陷病毒-1抗体及其使用方法 |
| CN119390828A (zh) * | 2024-12-31 | 2025-02-07 | 天津龙晟生物科技有限公司 | 人类免疫缺陷病毒hiv抗体及其应用和其检测产品 |
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| DE4236189A1 (de) | 1992-10-27 | 1994-04-28 | Boehringer Mannheim Gmbh | Verfahren zur simultanen Bestimmung von Antigenen und Antikörpern |
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| US6818392B2 (en) * | 2000-12-06 | 2004-11-16 | Abbott Laboratories | Monoclonal antibodies to human immunodeficiency virus and uses thereof |
| CA2809363A1 (en) * | 2010-08-24 | 2012-03-01 | Abbott Laboratories | Hiv core protein specific antibodies and uses thereof |
-
2000
- 2000-12-06 US US09/731,126 patent/US6818392B2/en not_active Expired - Lifetime
-
2001
- 2001-12-05 JP JP2002564544A patent/JP4489351B2/ja not_active Expired - Lifetime
- 2001-12-05 EP EP01273730A patent/EP1341820A2/en not_active Ceased
- 2001-12-05 EP EP10179020.2A patent/EP2336175B1/en not_active Expired - Lifetime
- 2001-12-05 ES ES10179020.2T patent/ES2619370T3/es not_active Expired - Lifetime
- 2001-12-05 CA CA2431321A patent/CA2431321C/en not_active Expired - Lifetime
- 2001-12-05 WO PCT/US2001/043179 patent/WO2002064615A2/en not_active Ceased
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2003
- 2003-11-17 US US10/714,689 patent/US7897332B2/en not_active Expired - Fee Related
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2004
- 2004-09-14 US US10/940,392 patent/US7531642B2/en not_active Expired - Fee Related
- 2004-09-14 US US10/940,237 patent/US7531638B2/en not_active Expired - Fee Related
- 2004-09-14 US US10/940,262 patent/US7531640B2/en not_active Expired - Fee Related
- 2004-09-14 US US10/940,162 patent/US7528238B2/en not_active Expired - Fee Related
- 2004-09-14 US US10/940,261 patent/US7531639B2/en not_active Expired - Lifetime
- 2004-09-14 US US10/940,344 patent/US7531641B2/en not_active Expired - Fee Related
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2011
- 2011-02-09 US US13/024,093 patent/US20120100632A1/en not_active Abandoned
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2012
- 2012-10-09 US US13/647,735 patent/US9115189B2/en not_active Expired - Fee Related
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| JP2004536568A (ja) | 2004-12-09 |
| US20050031624A1 (en) | 2005-02-10 |
| US7531639B2 (en) | 2009-05-12 |
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| US20050053924A1 (en) | 2005-03-10 |
| ES2619370T3 (es) | 2017-06-26 |
| US6818392B2 (en) | 2004-11-16 |
| US20040101831A1 (en) | 2004-05-27 |
| US20120100632A1 (en) | 2012-04-26 |
| US7531642B2 (en) | 2009-05-12 |
| US9115189B2 (en) | 2015-08-25 |
| US20050058994A1 (en) | 2005-03-17 |
| EP2336175B1 (en) | 2017-01-18 |
| CA2431321A1 (en) | 2002-08-22 |
| US20130130233A1 (en) | 2013-05-23 |
| US7531638B2 (en) | 2009-05-12 |
| WO2002064615A3 (en) | 2003-04-17 |
| EP2336175A1 (en) | 2011-06-22 |
| US7531641B2 (en) | 2009-05-12 |
| US7897332B2 (en) | 2011-03-01 |
| EP1341820A2 (en) | 2003-09-10 |
| US20020106636A1 (en) | 2002-08-08 |
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