JP4444506B2 - ヒトｉｌ−１エプシロンｄｎａおよびポリペプチド - Google Patents
ヒトｉｌ−１エプシロンｄｎａおよびポリペプチド Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- Bioinformatics & Cheminformatics (AREA)
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- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (7)
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| US9741398P | 1998-08-21 | 1998-08-21 | |
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| US9997498P | 1998-09-11 | 1998-09-11 | |
| US60/099,974 | 1998-09-11 | ||
| PCT/US1999/018771 WO2000011174A1 (en) | 1998-08-21 | 1999-08-20 | Human il-1 epsilon dna and polypeptides |
Publications (3)
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|---|---|
| JP2002523046A JP2002523046A (ja) | 2002-07-30 |
| JP2002523046A5 JP2002523046A5 (https=) | 2006-11-24 |
| JP4444506B2 true JP4444506B2 (ja) | 2010-03-31 |
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| EP (1) | EP1105485B1 (https=) |
| JP (1) | JP4444506B2 (https=) |
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| AU (1) | AU756913B2 (https=) |
| CA (1) | CA2340790C (https=) |
| CY (1) | CY1105226T1 (https=) |
| DE (1) | DE69932247T2 (https=) |
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| ES (1) | ES2263285T3 (https=) |
| NZ (1) | NZ510497A (https=) |
| PT (1) | PT1105485E (https=) |
| WO (1) | WO2000011174A1 (https=) |
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| CA2340790C (en) | 1998-08-21 | 2012-07-10 | Immunex Corporation | Human il-1 epsilon dna and polypeptides |
| CA2393532A1 (en) * | 1999-12-10 | 2001-06-14 | Frank J. Calzone | Interleukin-1 receptor antagonist-like molecules and uses thereof |
| WO2012048291A2 (en) | 2010-10-08 | 2012-04-12 | Proteapex Therapeutics Llc | Compositions and methods for inhibition of mmp:mmp-substrate interactions |
| US11884719B2 (en) | 2018-12-21 | 2024-01-30 | 23Andme, Inc. | Anti-IL-36 antibodies and methods of use thereof |
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| ZA811368B (en) | 1980-03-24 | 1982-04-28 | Genentech Inc | Bacterial polypedtide expression employing tryptophan promoter-operator |
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4411993A (en) | 1981-04-29 | 1983-10-25 | Steven Gillis | Hybridoma antibody which inhibits interleukin 2 activity |
| NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
| USRE32011E (en) | 1981-12-14 | 1985-10-22 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
| US4546082A (en) | 1982-06-17 | 1985-10-08 | Regents Of The Univ. Of California | E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins |
| US4737462A (en) | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
| US4543439A (en) | 1982-12-13 | 1985-09-24 | Massachusetts Institute Of Technology | Production and use of monoclonal antibodies to phosphotyrosine-containing proteins |
| US4518584A (en) | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
| US4902614A (en) | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
| US5071972A (en) | 1986-01-31 | 1991-12-10 | Genetics Institute, Inc. | DNA sequences encoding novel thrombolytic proteins |
| GB8628398D0 (en) | 1986-11-27 | 1986-12-31 | Central Blood Lab Authority | Pharmaceutically-active conjugates |
| US5011912A (en) | 1986-12-19 | 1991-04-30 | Immunex Corporation | Hybridoma and monoclonal antibody for use in an immunoaffinity purification system |
| US4965195A (en) | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
| US4968607A (en) | 1987-11-25 | 1990-11-06 | Immunex Corporation | Interleukin-1 receptors |
| CA1340772C (en) | 1987-12-30 | 1999-09-28 | Patricia Tekamp-Olson | Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences |
| WO1990005183A1 (en) | 1988-10-31 | 1990-05-17 | Immunex Corporation | Interleukin-4 receptors |
| EP0462145B1 (en) | 1989-03-07 | 1994-04-27 | Genentech, Inc. | Covalent conjugates of lipid and oligonucleotide |
| JP3205331B2 (ja) | 1989-03-14 | 2001-09-04 | 和光純薬工業株式会社 | アクロモバクタープロテアーゼｉ類遺伝子及びその遺伝子産物 |
| WO1990013641A1 (en) | 1989-05-10 | 1990-11-15 | Sloan-Kettering Institute For Cancer Research | Stably transformed eucaryotic cells comprising a foreign transcribable dna under the control of a pol iii promoter |
| WO1991004753A1 (en) | 1989-10-02 | 1991-04-18 | Cetus Corporation | Conjugates of antisense oligonucleotides and therapeutic uses thereof |
| WO1991006629A1 (en) | 1989-10-24 | 1991-05-16 | Gilead Sciences, Inc. | Oligonucleotide analogs with novel linkages |
| US5350683A (en) | 1990-06-05 | 1994-09-27 | Immunex Corporation | DNA encoding type II interleukin-1 receptors |
| AU651596B2 (en) | 1990-06-05 | 1994-07-28 | Immunex Corporation | Type II interleukin-1 receptors |
| US5262522A (en) | 1991-11-22 | 1993-11-16 | Immunex Corporation | Receptor for oncostatin M and leukemia inhibitory factor |
| US5449758A (en) * | 1993-12-02 | 1995-09-12 | Life Technologies, Inc. | Protein size marker ladder |
| US5783672A (en) | 1994-05-26 | 1998-07-21 | Immunex Corporation | Receptor for oncostatin M |
| US5863769A (en) * | 1997-01-28 | 1999-01-26 | Smithkline Beecham Corporation | DNA encoding interleukin-1 receptor antagonist (IL-1raβ) |
| US6197551B1 (en) | 1998-01-27 | 2001-03-06 | Millennium Pharmaceuticals, Inc. | Spoil-1 protein and nucleic acid molecules and uses therefor |
| WO1998047921A1 (en) * | 1997-04-21 | 1998-10-29 | Schering Corporation | Mammalian cytokines; related reagents and methods |
| EP1044271A1 (en) | 1998-01-09 | 2000-10-18 | Immunex Corporation | Il-1 delta dna and polypeptides |
| CA2340790C (en) | 1998-08-21 | 2012-07-10 | Immunex Corporation | Human il-1 epsilon dna and polypeptides |
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| PT1105485E (pt) | 2006-11-30 |
| AU756913B2 (en) | 2003-01-23 |
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| EP1105485B1 (en) | 2006-07-05 |
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