CA2340790C - Human il-1 epsilon dna and polypeptides - Google Patents

Human il-1 epsilon dna and polypeptides Download PDF

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Publication number
CA2340790C
CA2340790C CA2340790A CA2340790A CA2340790C CA 2340790 C CA2340790 C CA 2340790C CA 2340790 A CA2340790 A CA 2340790A CA 2340790 A CA2340790 A CA 2340790A CA 2340790 C CA2340790 C CA 2340790C
Authority
CA
Canada
Prior art keywords
polypeptide
seq
epsilon
biological activity
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2340790A
Other languages
English (en)
French (fr)
Other versions
CA2340790A1 (en
Inventor
John E. Sims
Dirk E. Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of CA2340790A1 publication Critical patent/CA2340790A1/en
Application granted granted Critical
Publication of CA2340790C publication Critical patent/CA2340790C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/545IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2340790A 1998-08-21 1999-08-20 Human il-1 epsilon dna and polypeptides Expired - Fee Related CA2340790C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US9741398P 1998-08-21 1998-08-21
US60/097,413 1998-08-21
US9859598P 1998-08-31 1998-08-31
US60/098,595 1998-08-31
US9997498P 1998-09-11 1998-09-11
US60/099,974 1998-09-11
PCT/US1999/018771 WO2000011174A1 (en) 1998-08-21 1999-08-20 Human il-1 epsilon dna and polypeptides

Publications (2)

Publication Number Publication Date
CA2340790A1 CA2340790A1 (en) 2000-03-02
CA2340790C true CA2340790C (en) 2012-07-10

Family

ID=27378375

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2340790A Expired - Fee Related CA2340790C (en) 1998-08-21 1999-08-20 Human il-1 epsilon dna and polypeptides

Country Status (13)

Country Link
US (1) US7659375B2 (https=)
EP (1) EP1105485B1 (https=)
JP (1) JP4444506B2 (https=)
AT (1) ATE332373T1 (https=)
AU (1) AU756913B2 (https=)
CA (1) CA2340790C (https=)
CY (1) CY1105226T1 (https=)
DE (1) DE69932247T2 (https=)
DK (1) DK1105485T3 (https=)
ES (1) ES2263285T3 (https=)
NZ (1) NZ510497A (https=)
PT (1) PT1105485E (https=)
WO (1) WO2000011174A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2340790C (en) 1998-08-21 2012-07-10 Immunex Corporation Human il-1 epsilon dna and polypeptides
CA2393532A1 (en) * 1999-12-10 2001-06-14 Frank J. Calzone Interleukin-1 receptor antagonist-like molecules and uses thereof
WO2012048291A2 (en) 2010-10-08 2012-04-12 Proteapex Therapeutics Llc Compositions and methods for inhibition of mmp:mmp-substrate interactions
US11884719B2 (en) 2018-12-21 2024-01-30 23Andme, Inc. Anti-IL-36 antibodies and methods of use thereof

Family Cites Families (33)

* Cited by examiner, † Cited by third party
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ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4411993A (en) 1981-04-29 1983-10-25 Steven Gillis Hybridoma antibody which inhibits interleukin 2 activity
NZ201705A (en) 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
USRE32011E (en) 1981-12-14 1985-10-22 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4546082A (en) 1982-06-17 1985-10-08 Regents Of The Univ. Of California E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins
US4737462A (en) 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4543439A (en) 1982-12-13 1985-09-24 Massachusetts Institute Of Technology Production and use of monoclonal antibodies to phosphotyrosine-containing proteins
US4518584A (en) 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4902614A (en) 1984-12-03 1990-02-20 Teijin Limited Monoclonal antibody to human protein C
US5071972A (en) 1986-01-31 1991-12-10 Genetics Institute, Inc. DNA sequences encoding novel thrombolytic proteins
GB8628398D0 (en) 1986-11-27 1986-12-31 Central Blood Lab Authority Pharmaceutically-active conjugates
US5011912A (en) 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
US4965195A (en) 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4968607A (en) 1987-11-25 1990-11-06 Immunex Corporation Interleukin-1 receptors
CA1340772C (en) 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
WO1990005183A1 (en) 1988-10-31 1990-05-17 Immunex Corporation Interleukin-4 receptors
EP0462145B1 (en) 1989-03-07 1994-04-27 Genentech, Inc. Covalent conjugates of lipid and oligonucleotide
JP3205331B2 (ja) 1989-03-14 2001-09-04 和光純薬工業株式会社 アクロモバクタープロテアーゼi類遺伝子及びその遺伝子産物
WO1990013641A1 (en) 1989-05-10 1990-11-15 Sloan-Kettering Institute For Cancer Research Stably transformed eucaryotic cells comprising a foreign transcribable dna under the control of a pol iii promoter
WO1991004753A1 (en) 1989-10-02 1991-04-18 Cetus Corporation Conjugates of antisense oligonucleotides and therapeutic uses thereof
WO1991006629A1 (en) 1989-10-24 1991-05-16 Gilead Sciences, Inc. Oligonucleotide analogs with novel linkages
US5350683A (en) 1990-06-05 1994-09-27 Immunex Corporation DNA encoding type II interleukin-1 receptors
AU651596B2 (en) 1990-06-05 1994-07-28 Immunex Corporation Type II interleukin-1 receptors
US5262522A (en) 1991-11-22 1993-11-16 Immunex Corporation Receptor for oncostatin M and leukemia inhibitory factor
US5449758A (en) * 1993-12-02 1995-09-12 Life Technologies, Inc. Protein size marker ladder
US5783672A (en) 1994-05-26 1998-07-21 Immunex Corporation Receptor for oncostatin M
US5863769A (en) * 1997-01-28 1999-01-26 Smithkline Beecham Corporation DNA encoding interleukin-1 receptor antagonist (IL-1raβ)
US6197551B1 (en) 1998-01-27 2001-03-06 Millennium Pharmaceuticals, Inc. Spoil-1 protein and nucleic acid molecules and uses therefor
WO1998047921A1 (en) * 1997-04-21 1998-10-29 Schering Corporation Mammalian cytokines; related reagents and methods
EP1044271A1 (en) 1998-01-09 2000-10-18 Immunex Corporation Il-1 delta dna and polypeptides
CA2340790C (en) 1998-08-21 2012-07-10 Immunex Corporation Human il-1 epsilon dna and polypeptides

Also Published As

Publication number Publication date
AU5777799A (en) 2000-03-14
US20080108796A1 (en) 2008-05-08
DK1105485T3 (da) 2006-10-30
CY1105226T1 (el) 2010-03-03
ES2263285T3 (es) 2006-12-01
DE69932247T2 (de) 2007-05-31
ATE332373T1 (de) 2006-07-15
JP4444506B2 (ja) 2010-03-31
EP1105485A1 (en) 2001-06-13
PT1105485E (pt) 2006-11-30
AU756913B2 (en) 2003-01-23
JP2002523046A (ja) 2002-07-30
DE69932247D1 (de) 2006-08-17
WO2000011174A1 (en) 2000-03-02
US7659375B2 (en) 2010-02-09
NZ510497A (en) 2003-09-26
EP1105485B1 (en) 2006-07-05
CA2340790A1 (en) 2000-03-02

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20150820