JP4434357B2 - Automatic analyzer - Google Patents

Description

[0001]
BACKGROUND OF THE INVENTION
The present invention relates to an automatic analyzer that performs component analysis of a sample such as serum, and more particularly to management of various solutions or reagents used in the apparatus.
[0002]
[Prior art]
In an automatic analyzer that automatically analyzes the components of samples such as serum, take the sample (specimen) you want to measure in a cup or blood collection tube, place it in a sample rack where you can mount it, place it on a sampler, and measure it for each sample. Ingredients are registered in the device as requested items and are automatically measured.
[0003]
In the measurement, a diluted solution or a dedicated reagent (hereinafter, various solutions or reagents to be used are collectively referred to as “reagents”) is added to the target sample for each requested item, and after stirring, Based on a calibration curve obtained by measurement (calibration) of a sample (standard sample) whose concentration can be specified in advance, the concentration is obtained by absorbance measurement or potential measurement.
[0004]
Conventionally, with the function to recognize the installed reagent such as reagent barcode, the function to detect the remaining amount of reagent, the function to detect the environment (temperature, humidity, etc.) in the device, the function to manage the date and time (calendar), etc. Various controls have been automated in automated analyzers.
[0005]
In recent years, more and more samples have been handled in automatic analyzers, and accordingly, the speed of measurement processing has been required. In order to cope with this, for the measurement of the same measurement item, a plurality of reagent containers containing the same type of reagent are installed on the apparatus, and the remaining amount of the reagent in the reagent container in use becomes a predetermined value or less. When the specific condition is satisfied, control is performed such that the measurement of the same measurement item is not interrupted by using a reagent contained in another reagent container (crossing the reagent container). Here, the specific condition (that is, the condition across the reagent container) is, for example, as follows.
[0006]
(1) When the remaining amount of reagent in the container being used is exhausted or below the specified set value
(2) When the expiration date of the reagent in the container being used has expired
(3) When an operator's predetermined operation is performed for some reason
Furthermore, an operation control is performed in which alarms (warnings) indicating various states and conditions relating to the reagent are notified to the operator by screen display or sound, and in some cases, the measurement is automatically stopped. Examples of alarm types include the following.
(1) Alarm indicating that the remaining amount of reagent in the container in use has run out, or has fallen below a predetermined set value
(2) An alarm indicating that the remaining amount of reagent in the container being used has fallen below a preset warning (for alarm) value
(3) Alarm indicating that the expiration date of the reagent in the container being used has passed
(4) Alarm indicating that the reagent lot in the container being used has changed
(5) An alarm indicating that the container has been transferred to another container.
(6) An alarm indicating that the environmental conditions (temperature, humidity, etc.) in the reagent storage storing the container are out of control
By the way, in recent years, more items have been handled by automatic analyzers, and in accordance with this, preparation reagents and various types of reagents with special properties are mixed with common reagents and installed at the same time for measurement. There are a lot of cases to do. For example, a reagent that has an expiration date after the start of use corresponds to this.
[0007]
Here, with regard to reagent management, management items that have been implemented conventionally include lot management and expiration date management. For example, the reagent used for the measurement is assigned an identification number for each production lot (or container), and quality control (QC: Quality Control) based on these identification numbers is performed. In addition, a reagent provided in a container and provided by a supplier is usually given an expiration date. With conventional automatic analyzers, for example, the expiration date assigned to the container from the time of provision is managed and expired. The use of this reagent prevents the accuracy of component analysis from being reduced.
[0008]
[Problems to be solved by the invention]
However, the expiration date management of the reagent performed in the conventional apparatus is irrelevant to the presence or absence of the use of the reagent, and the expiration date (deterioration) management after the start of the reagent usage is not performed. In addition, the reagent after the start of use may be kept cold (maintain the storage environment) in a reagent warehouse that has been energized for 24 hours. It wasn't done. In other words, all of the reagent management related to these matters has been performed by the operator himself. For this reason, there is a possibility that mistakes may occur in reagent management such as deterioration and evaporation, and there is a problem that complete reagent management cannot be performed.
[0009]
The present invention has been made in view of such circumstances, and in addition to the expiration date assigned to the reagent from the beginning, it is more sophisticated by managing the effective period after use, storage temperature, storage humidity, etc. An object of the present invention is to provide an automatic analyzer that can perform accurate reagent management and reduce the operational burden on the operator.
[0010]
[Means for Solving the Problems]
In order to solve the above problems and achieve the object, the automatic analyzer of the present invention is configured as follows.
[0011]
An automatic analyzer according to one aspect of the present invention is: In an automatic analyzer that analyzes a measurement item of the test sample by dispensing the reagent into a reaction container in which the test sample is stored and reacting, and measuring the reaction result, the storage temperature control value of the reagent and Setting means for setting reagent information indicating an allowable period after the storage temperature of the reagent deviates from the storage temperature control value, detection means for detecting the start of use of the reagent, and detection of start of use detected by the detection means Temperature measuring means for measuring the storage temperature of the reagent after being deviated, and the storage temperature measured by the temperature measuring means deviates from the storage temperature management value indicated by the reagent information set by the setting means Time measuring means for measuring elapsed time, and detection for detecting whether the elapsed time measured by the time measuring means has exceeded an allowable period indicated by the reagent information set by the setting means Automatic analyzer characterized by comprising a stage, a It is.
[0027]
DETAILED DESCRIPTION OF THE INVENTION
Hereinafter, embodiments of the present invention will be described with reference to the drawings.
FIG. 1 is a perspective view showing an external appearance of an automatic analyzer according to an embodiment of the present invention. The disc-shaped reaction disk 1 in which a plurality of reaction cells are arranged on the circumference performs an intermittent rotation operation of rotating and stopping at a predetermined angle in a certain cycle. A sample disk 2 in which a sample container (test sample container (including a blood collection tube), not shown) in which a test sample is accommodated is set is disposed in the vicinity of the reaction disk 1 at a predetermined interval.
[0028]
The first reagent storage 3 in which reagent bins containing reagents that react with various components are set is arranged inside the reaction disk 1, and the reagent bin is set in the same manner as the first reagent storage 3. The second reagent storage 4 is arranged in the vicinity of the reaction disk 1 with a predetermined interval.
[0029]
The sample disk 2 rotates so that a designated sample container (blood collection tube) is positioned at a predetermined position. The first reagent storage 3 and the second reagent storage 4 also rotate so that the designated reagent container is positioned at a predetermined position.
[0030]
A sample arm 5 is disposed between the reaction disk 1 and the sample disk 2, and a sample probe 6 is attached to the tip thereof. The sample arm 5 positions the sample probe 6 on the sample container set at a predetermined position of the sample disk 2. Here, when the sample probe 6 is lowered into the sample container and the liquid level is detected, the sample probe 6 is further lowered by a predetermined amount to suck the test sample by a predetermined amount, and rises when this suction is completed.
[0031]
When the raising of the sample probe 6 is completed, the sample arm 5 rotates and positions the sample probe 6 on the sample dispensing position of the reaction disk 1. Here, the sample probe 6 dispenses a test sample by a preset amount to the reaction cell set at the sample dispensing position.
[0032]
A first reagent arm 8 is disposed in the vicinity of the outer periphery of the reaction disk 1, and a first reagent probe 9 is attached to the tip thereof. The first reagent arm 8 positions the first reagent probe 9 on the reagent bottle set at a predetermined position of the first reagent storage 3. Here, the first reagent probe 9 descends into the reagent bottle. When the liquid level is detected, the first reagent probe 9 further descends by a predetermined amount and sucks the reagent by a predetermined amount, and rises when the suction is completed.
[0033]
When the raising of the first reagent probe 9 is completed, the first reagent arm 8 rotates to place the first reagent probe 9 on the first reagent dispensing position of the reaction disk 1. Here, the first reagent probe 9 dispenses a predetermined amount of the reagent into the reaction cell set at the first reagent dispensing position.
[0034]
A second reagent arm 10 is disposed between the reaction disk 1 and the second reagent storage 4, and a second reagent probe 11 is attached to the tip of the second reagent arm 10. The second reagent arm 10 positions the second reagent probe 11 on the reagent bottle set at a predetermined position of the second reagent storage 4.
Here, the second reagent probe 11 descends into the reagent bottle. When the liquid level is detected, the second reagent probe 11 further descends by a predetermined amount and sucks the reagent by a predetermined amount, and rises when this aspiration is completed. When the raising of the second reagent probe 11 is completed, the second reagent arm 10 is rotated to position the second reagent probe 11 on the second reagent dispensing position of the reaction disk 1.
Here, the second reagent probe 11 dispenses a predetermined amount of reagent into the reaction cell set at the second reagent dispensing position.
[0035]
Further, a first stirring arm 12 and a second stirring arm 13 are arranged near the outer periphery of the reaction disk 1, and a stirring bar is attached to each tip. The first stirring arm 12 and the second stirring arm 13 stir the solution (test sample and reagent) in the reaction cell set at the first stirring position and the second stirring position of the reaction disk 1 with a stirring bar, respectively. To do.
[0036]
Further, a cleaning unit 14 is disposed in the vicinity of the outer periphery of the reaction disk 1, and a plurality of cleaning nozzles and a drying nozzle are attached to the cleaning unit 14. The cleaning unit 14 performs cleaning or drying with respect to each reaction cell set at the cleaning position of the reaction disk 1 by a cleaning nozzle or a drying nozzle.
In addition, an electrolyte unit 15 can be arranged as an option near the outer periphery of the reaction disk 1 so that the electrolyte can be analyzed.
[0037]
A photometric unit 16 is provided at one place on the reaction disk 1. The photometric unit 16 includes a light emitting unit, irradiates the reaction cell set at the photometric position of the reaction disk 1 with light from the light emitting unit, measures the amount of transmitted light, and samples the reaction cell. The amount of change due to these reagents is measured. Component analysis (quantitative analysis / qualitative analysis) of the test sample is performed based on the measured change amount.
[0038]
The reaction disk 1 has a thermostatic chamber structure in order to keep the temperature of the reaction cell at a preset temperature, and the first reagent container 3 and the second reagent container 4 have the reagent bottle (reagent) temperature set in advance. It has a cooling structure to maintain the set temperature.
[0039]
FIG. 2 is a block diagram illustrating a functional configuration of the automatic analyzer according to the present embodiment. As shown in the figure, a reagent information management function unit 37, a standard sample information management function unit 39, a dose information display function unit 41, an accuracy management information display function unit 43, an item parameter management function unit 44, and a calibration item setting function Unit 45, measurement sample (specimen) item (limited) function unit 49, date and time (calendar) function unit 51, and these functional units are realized as user interface software and a storage medium such as a memory or HDD. . These functional units can process setting input from a user through a console 53 including a display device 55 and an input device 57 to display various information.
[0040]
These functional units are connected via the control unit 20 to the reagent information reading means 21, the reagent amount detection means 23, the in-device environment detection means 25, the standard sample amount detection means 27, the sample measurement various means 29, the mechanism control means 31, The rack information detecting means 33 and the sample (sample) barcode reading means 35 are connected. These means are realized as various mechanisms, hardware, control software, etc. for realizing the component analysis (quantitative analysis / qualitative analysis) of the test sample described with reference to FIG.
[0041]
The control unit 20 is a control unit including a CPU and a memory, and controls operation of the entire automatic analyzer.
[0042]
In the automatic analyzer of the present embodiment, general operations / operations from setting of reagent information to calibration and measurement based on an inspection request are as follows (1) to (3), for example.
[0043]
(1) Reagent information, standard sample information, item parameter settings
With the functions of the reagent information management function unit 37, the standard sample information management function unit 39, and the item parameter management function unit 44, necessary parameters can be set / stored / displayed for various measurement items such as reagents, standard samples, and total protein TP. This is performed by an operator via the display device 55 and the input device 57. That is, here, in addition to settings related to identification names such as TP, concentration calculations, and calculation result management values, the standard samples used to set the reagents used and the doses used for concentration calculations, and the standard samples used for accuracy control Settings are made. For each standard sample, a sample name and a known concentration value are set for each item. For each reagent, a reagent name, a reagent type (such as “first reagent”, “second reagent”, and “detergent”), a reagent expiration date, a lot number, and the like are set.
[0044]
In addition, in the setting of the item parameter, an item parameter for automatically performing calibration and continuing sample measurement when a condition for crossing (moving) the reagent container occurs may be set.
[0045]
(2) Calibration
A predetermined standard sample and a reagent are arranged at a predetermined location in the apparatus, and the function of the calibration item setting function unit 45 instructs the apparatus to calibrate the predetermined item.
[0046]
The control unit 20 obtains various types of information from the rack information detection unit 31, the reagent amount detection unit 23, and the standard sample amount detection unit 27, and operates the sampling probe and the sampling arm by the mechanism control unit 31 so that the standard sample, the reagent, Is dispensed into a reaction tube and stirred. Further, the mechanism control means 31 is controlled to cause the sample tube various means 29 to perform real-time measurement (photometry, potential measurement) while moving the reaction tube at regular intervals, and the result is stored in the memory.
[0047]
During such a calibration operation, the reagent remaining amount, the temperature and humidity in the apparatus, and the standard sample remaining amount are detected by the reagent amount detection means 23, the apparatus internal environment detection means 25, and the standard sample amount detection means 27, respectively. . In addition, the expiration date of the reagent is also monitored by the date / time (calendar) function unit 51. If an error is detected here, the error display described in the section of the prior art is performed. In addition, reagent management unique to the present invention described later is also performed.
[0048]
During calibration, if the conditions for moving the reagent container are met or the standard sample is insufficient during the calibration, the calibration operation cannot be continued. Then, the measurement is finished after waiting for the result output of the sample already being measured, or other items are continuously measured.
[0049]
After such a calibration operation, the operator confirms the state of the apparatus (validity of the calibration curve) based on the result display displayed by the calibration curve information display function unit 43, and repeats the calibration operation if there is a problem. Instruct.
[0050]
(3) Specify the test request, measure the sample, and report the result
A sample is placed in a predetermined rack or installation position, an inspection request is designated by the operator in the measurement sample item setting function unit 47, and execution of the measurement operation is instructed to the apparatus. Along with the measurement related to the requested test, the quality control item setting function unit 49 instructs the quality control sample measurement before, during, or during the measurement of the sample.
[0051]
In the measurement based on the examination request, the control unit 20 controls the specimen barcode reading means 35 and the rack information detection means 33 to detect the presence of the specimen, and automatically searches for and obtains the requested information. Further, the measurement operation similar to the calibration is performed based on the obtained information, the concentration calculation is executed based on the calibration curve established by the calibration, and the result is stored in a memory or the like. The concentration calculation result is displayed on the display device 55 or output from the output means 36. The output by the output unit 36 is, for example, print output by a printer (not shown), and is transfer to a host computer or the like via a communication unit.
[0052]
During the measurement operation related to the inspection request, the reagent remaining amount, the temperature and humidity in the apparatus, and the standard sample remaining amount are detected by the reagent amount detecting means 23, the in-apparatus environment detecting means 25, and the standard sample amount detecting means 27, respectively. . In addition, the expiration date of the reagent is also monitored by the date / time (calendar) function unit 51. If an error is detected here, the error display described in the section of the prior art is performed. In addition, reagent management unique to the present invention described later is also performed.
[0053]
During the measurement operation related to the inspection request, the measurement operation cannot be continued if the conditions for moving the reagent container are satisfied or the standard sample is insufficient during the operation, so the measurement operation cannot be continued for this item. Display that it is possible and wait for the result output of the sample that is already being measured to end the measurement, or continue to measure other items.
[0054]
However, regarding the movement of the reagent container, if automatic calibration execution is designated, recalibration is automatically executed, and measurement is continued.
[0055]
In the automatic analyzer according to the present embodiment, the reagent information management function unit 37 can set reagent information for each reagent such as reagent recognition information (name, etc.), lot number, expiration date, and the like. In addition to information, it is possible to set the effective period (hours) after the start of use, the temperature management range (° C), the allowable period outside temperature management (minutes), the humidity management range (%), and the allowable period outside humidity management (minutes). The reagent management is performed after the use of the reagent is started.
[0056]
FIG. 3 is a diagram showing an example of a screen for the operator to set reagent information.
[0057]
For example, in this embodiment, the reagent ID “99010001”, reagent name “Ca”, reagent type “R-1”, bottle type “100 ml”, lot number “00001”, expiration date are displayed via this reagent information setting screen. “2000/1/1”, effective period after start of use “20 hours”, temperature management range “8 ° C. to 13 ° C.”, temperature management range permissible period “2 minutes”, humidity management range “40% to 70%” , It is assumed that the humidity management range is set to the allowable period “2 minutes”.
[0058]
Each reagent is affixed with a barcode that allows the reagent to be distinguished from other reagents, and when the barcode is read from the reagent information reading means 21, it is detected that the use of the reagent has started. In this configuration, the measurement of the reagent installation status, the temperature in the reagent storage, and the humidity by the internal environment detection means 25 are started. As described above, in addition to the method of detecting (judging) that the use of the reagent is started when the reagent barcode is read, the use is started when the reagent aspiration for measurement is first performed, The start of use of the reagent may be manually recognized based on the operation from.
[0059]
It should be noted that the effective period (hours), the temperature management range (° C.), the temperature management allowable period (minutes), the humidity management range (%), and the humidity management outside after the start of use of the reagent set by the reagent information management function unit 37 Information indicating the permissible period (minutes) may be recorded in advance in the barcode, and a configuration in which the setting by the reagent information management function unit 37 is unnecessary may be employed.
[0060]
With respect to the reagent that has been recognized to have started to be used, the check of the above five items, that is, the reagent management process after the start of reagent use is started. This reagent management process is continued until the reagent is removed from the apparatus, until the reagent is empty, or until the remaining amount of the reagent falls below a specified amount.
[0061]
More specifically, for example, error determination related to reagent management (see [Error Details] shown below) is performed after starting use every other minute. When an error is detected, the reagent installation position and reagent recognition information are displayed on the screen. An alarm (warning) is displayed on the screen together with a buzzer sound (warning sound). When an error having a high priority occurs, the container is passed to the same type of effective reagent in another container (that is, an error does not occur including the effective period). Note that the container may be crossed when an error occurs regardless of the priority order. If there is no effective reagent, the item is masked out and measurement is not performed even if requested (measurement is stopped). In this case, the fact that the measurement was not performed is displayed on the screen together with the sample information, and the operator is notified.
[0062]
In addition, even if an error with a high priority occurs, measurement is continued, and the fact that an error has occurred (for example, the following three-character error code) is displayed on the screen or printed. May be.
[0063]
[Error details]
Error (1): Valid period exceeded after start of use, priority: high, error code RTM
Error (2): Temperature management range deviation, priority: low
Error (3): Deviated temperature management range and the elapsed time exceeds the allowable period, priority: high, error code: RTO
Error (4): Humidity management range deviation, priority: low
Error (5): Deviation of humidity control range and the elapsed time exceeds the allowable period, priority: high, error code: RHO
FIG. 4 is a flowchart showing details of reagent management after the start of use according to the present invention.
[0064]
First, a variable representing the elapsed time after the start of use of the reagent (for example, reagent ID: 9900001, reagent name: Ca shown in FIG. 3) is incremented by 1 (step S1: measurement of usage time).
[0065]
This variable is initialized (= 0) when it is detected that the use of the reagent is started, and is incremented by 1 in step S1 every time the reagent management process is started after the start of use. For example, if the reagent management process is started every other minute after the start of use, for example, if it has already been started five times, the value of this variable is 5 and the elapsed time is counted as 5 minutes.
[0066]
Next, after converting this variable from minutes to hours, it is compared with an effective period after the start of use of the reagent (in this case, “20 hours”) to determine whether or not the effective period has been exceeded (step S2). ). If it exceeds, an error display (error (1)) indicating that in step S3.
[0067]
Next, the variable “temperature” representing the measured storage temperature of the reagent is compared with the temperature management range of the reagent (in this case, “8 ° C. to 13 ° C.”), and whether or not the temperature management range is deviated. Is determined (step S4). If it deviates, the variable a representing the elapsed time after deviating from the temperature management range is incremented by 1 (step S5). At this time, an error display (error (2)) may be performed. The variable a is used for counting the elapsed time in the same manner as the variable for the elapsed time after the start of use.
[0068]
In subsequent step S7, it is determined whether or not the variable a exceeds the allowable period (in this case, “2 minutes”) after deviating from the temperature management range of the reagent (step S7). If it exceeds, an error display (error (3)) indicating that in step S8.
[0069]
On the other hand, if it is determined in step S4 that the temperature of the reagent does not deviate from the temperature management range, a variable a representing the elapsed time after deviating from the temperature management range is initialized to 0 (step S6).
[0070]
Next, the variable “humidity” representing the measured storage humidity of the reagent is compared with the humidity management range of the reagent (in this case, “40% to 70%”), and whether or not the humidity management range is deviated. Is determined (step S9). When deviating, the variable b representing the elapsed time after deviating from the humidity management range is incremented by 1 (step S10). At this time, an error display (error (4)) may be performed. The variable b is used for counting the elapsed time in the same manner as the variable for the elapsed time after the start of use.
[0071]
In the subsequent step S12, it is determined whether or not the variable b has exceeded the allowable period (in this case, “2 minutes”) after deviating from the humidity management range of the reagent (step S12). If it exceeds, an error display (error (5)) indicating that in step S13.
[0072]
On the other hand, when it is determined in step S9 that the humidity of the reagent does not deviate from the humidity management range, a variable b representing an elapsed time after deviating from the humidity management range is initialized to 0 (step S11).
[0073]
Note that the date / time (calendar) function unit 51 included in the automatic analyzer of the present embodiment is backed up by an auxiliary power source and can continue time measurement even if a power failure occurs.
[0074]
According to the automatic analyzer of the present embodiment described above, the reagent deterioration is automatically determined by the reagent management after the start of use, and the operator is notified as an error display. Therefore, the work burden for managing the deterioration of the reagent, which has been performed by the operator himself, is greatly reduced or unnecessary. This makes it possible to operate a highly reliable device.
[0075]
The present invention is not limited to the above-described embodiment, and can be implemented with various modifications.
[0076]
【The invention's effect】
As described above, according to the present invention, in addition to the expiration date assigned to the reagent from the beginning, more advanced reagent management can be performed by managing the effective period after use, storage temperature, storage humidity, etc. An automatic analyzer that can reduce the operation burden on the operator can be provided.
[Brief description of the drawings]
FIG. 1 is a perspective view showing the appearance of an automatic analyzer according to an embodiment of the present invention.
FIG. 2 is a block diagram showing a functional configuration of the automatic analyzer according to the embodiment.
FIG. 3 is a diagram showing an example of a screen for an operator to set reagent information
FIG. 4 is a flowchart showing details of reagent management after start of use according to the present invention.
[Explanation of symbols]
20 ... Control unit
21 ... Reagent information reading means
23. Reagent amount detection means
25. In-device environment detection means
27 ... Standard sample amount detection means
29 ... Various means for sample measurement
31. Mechanism control means
33 ... Rack information detection means
35 ... Sample barcode reading means
36: Output means
37. Reagent information management function section
39 ... Standard sample information management function
41 ... Calibration curve information display function section
43 ... Quality control information display function section
44 ... Item parameter management function
45 ... Calibration item setting function section
47 ... Quality control item setting function section
49 ... Measurement sample (specimen) item (limited) function section
51 ... Date and time (calendar) function part
53 ... Console
55. Display device
57 ... Input device

Claims (10)

In an automatic analyzer that analyzes the measurement items of the test sample by dispensing the reagent into the reaction container in which the test sample is contained and reacting, and measuring the reaction result,
Setting means for setting reagent information indicating an allowable period after the storage temperature management value of the reagent and the storage temperature of the reagent deviate from the storage temperature management value;
Detecting means for detecting the start of use of the reagent;
Temperature measuring means for measuring the storage temperature of the reagent after the start of use is detected by the detecting means;
A time measuring means for measuring an elapsed time after the storage temperature measured by the temperature measuring means deviates from a storage temperature management value indicated by the reagent information set by the setting means;
An automatic analyzer comprising: detecting means for detecting whether or not an elapsed time measured by the time measuring means has exceeded an allowable period indicated by the reagent information set by the setting means. 2. The automatic analyzer according to claim 1 , further comprising warning means for displaying a warning screen or outputting a warning sound indicating that the elapsed time exceeds the allowable period. The detection means detects the use of the reagent by at least one of reading a barcode attached to the reagent, detecting the first suction of the reagent, and manually recognizing the start of use of the reagent based on an operation from an operator. The automatic analyzer according to claim 1 or 2 , which detects that it has been started. A barcode attached to the reagent, on which reagent information indicating at least a storage temperature management value of the reagent and a permissible period after the storage temperature of the reagent deviates from the storage temperature management value;
A reading means for reading the reagent information recorded in the bar code,
The time measuring unit measures an elapsed time after the storage temperature measured by the temperature measuring unit deviates from a storage temperature management value indicated by the reagent information read by the reading unit,
The detecting device, the elapsed time measured by said time measuring means, according to claim 1 to 3, characterized in that for detecting whether or not exceeded the permissible time indicated by the reagent information read by the reading means The automatic analyzer as described in any one of. When the elapsed time exceeds the allowable period, the reagent of the same type as the reagent contained in a reagent container different from the container containing the reagent is dispensed, or the measurement is stopped. The automatic analyzer according to any one of claims 1 to 3 , wherein warning information is given to the measurement result. In an automatic analyzer that analyzes the measurement items of the test sample by dispensing the reagent into the reaction container in which the test sample is contained and reacting, and measuring the reaction result,
Setting means for setting reagent information indicating an allowable period after the storage humidity management value of the reagent and the storage humidity of the reagent deviate from the storage humidity management value;
Detecting means for detecting the start of use of the reagent;
Humidity measuring means for measuring the storage humidity of the reagent after the start of use is detected by the detecting means;
A time measuring means for measuring an elapsed time after the storage humidity measured by the humidity measuring means deviates from a storage humidity management value indicated by the reagent information set by the setting means;
An automatic analyzer comprising: detecting means for detecting whether or not an elapsed time measured by the time measuring means has exceeded an allowable period indicated by the reagent information set by the setting means. 7. The automatic analyzer according to claim 6 , further comprising warning means for displaying a warning screen indicating the fact or outputting a warning sound when the elapsed time exceeds the allowable period. The detection means detects the use of the reagent by at least one of reading a barcode attached to the reagent, detecting the first suction of the reagent, and manually recognizing the start of use of the reagent based on an operation from an operator. The automatic analyzer according to claim 6 or 7 , which detects that it has been started. A barcode that is attached to the reagent and records reagent information indicating at least a storage humidity management value of the reagent and a permissible period after the storage humidity of the reagent deviates from the storage humidity management value;
A reading means for reading the reagent information recorded in the bar code,
The time measuring unit measures an elapsed time after the storage humidity measured by the humidity measuring unit deviates from a storage humidity management value indicated by the reagent information read by the reading unit,
The detecting device, the elapsed time measured by said time measuring means, according to claim 6 to 8, characterized in that detecting whether exceeded the permissible period indicated by the reagent information read by the reading means The automatic analyzer as described in any one of. When the elapsed time exceeds the allowable period, the reagent of the same type as the reagent contained in a reagent container different from the container containing the reagent is dispensed, or the measurement is stopped. Or an automatic analyzer according to any one of claims 6 to 8 , wherein warning information is added to a result of the measurement.

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