JP2007322393A - Autoanalyzer, precision control method thereof, and program for precision control - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To perform accurate and precise precision control while reducing the load of a worker and suppressing cost low. <P>SOLUTION: This autoanalyzer includes a sample vial housing a predetermined sample and having a data code recording part for recording the data code obtained by encoding discrimination data for discriminating the sample; a vial holding part for holding the sample vial in a thermostatic state; a data code reading part for reading the data code recorded by the data code recording part of the sample vial held by the vial holding part; a transmission and reception part connected to a plurality of autoanalyzers through a communication network and storing the analytic data necessary when the sample is analyzed and performing the transmission and reception of data with respect to a control system for totalizing the analytical results transmitted from the respective autoanalyzers; and a control part for controlling the reaction of the sample corresponding to the data code with a predetermined reagent using the analytical data received from the control system and performing operation for analyzing the component of the sample on the basis of the reaction result. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to an automatic analyzer that automatically analyzes a sample such as blood or body fluid, an accuracy management method of the automatic analyzer, and an accuracy management program.

  Conventionally, an automatic analyzer is known as a device for biochemically or immunologically analyzing a specimen such as blood or body fluid. This automatic analyzer performs accuracy management for ensuring the accuracy and precision of analysis. There are two types of quality control. Internal quality control is performed regularly several times a day inside the facility where the automatic analyzer is installed, and it is held several times a year and measured at other facilities. There is external quality control that compares the analysis results.

  Among these, quality control samples are used for internal quality control. In this case, the quality control sample is transferred from the vial to a specified sample cup and placed at a predetermined position of the automatic analyzer. A predetermined amount of the quality control sample transferred to the sample cup is dispensed into a reaction container held by the automatic analyzer. In this reaction container, a reagent corresponding to the inspection item is also dispensed, the reaction occurring between this reagent and the quality control sample is optically measured, and the components of the quality control sample are analyzed using the measurement result.

  The information required for analysis of the quality control sample may change depending on the lot. Therefore, if the quality control sample of a different lot is used, the information required for the analysis is automatically analyzed. Need to be re-entered. Such information is generally input manually by an operator (operator) using an input means such as a keyboard (see, for example, Patent Document 1). However, since there is an enormous amount of information that needs to be input, there is a problem that it takes time for an operator to input and an input error tends to occur.

  In order to solve this problem, a container provided with a one-dimensional barcode for recording a sample identification code and a lot number, and a reagent bottle provided with a two-dimensional barcode for recording more detailed information about the sample are provided. A technique has been disclosed that eliminates the labor of complicated input work by an operator (see, for example, Patent Document 2).

JP-A-11-211731 JP-A-8-94626

  However, in the conventional techniques described above, it is necessary to move the quality control sample to a sample container such as a test tube or a sample cup in any case. For this reason, in order to perform accurate measurement, the operator must correctly recognize the installation position of the sample and install it so that there is no mistake, and this sample installation work may be a burden on the operator. It was.

  In addition, when transferring a quality control sample to a sample container, the operator tends to move a slightly larger amount of the sample than necessary, so that a sample that has not been used for the actual measurement is the sample. There is a problem in that it remains in the container and is costly due to waste of an expensive quality control sample.

  Furthermore, in the case of the technique disclosed in Patent Document 2, it is necessary to install reading means having a function of reading a one-dimensional barcode and a two-dimensional barcode, and by providing such a function. There was a problem that the automatic analyzer became expensive.

  In addition to these internal quality control problems, external quality control is held only a few times a year as described above, so even if there are significant differences between the measurement results and the population, It was difficult to grasp the facts immediately.

  The present invention has been made in view of the above, an automatic analyzer that can perform accurate and precise accuracy management while reducing the burden on the operator and keeping the cost low, an accuracy management method of the automatic analyzer, It is another object of the present invention to provide a quality control program.

  In order to solve the above-mentioned problems and achieve the object, the invention according to claim 1 is an automatic analyzer for analyzing the components of the sample by reacting the sample with a predetermined reagent, the predetermined sample A sample vial having an information code recording unit that records an information code in which identification information for identifying the sample is encoded, a vial holding unit that holds the sample vial in a constant temperature state, and the vial holding unit holds An information code reading unit that reads an information code recorded by an information code recording unit of a sample vial that is connected to a plurality of automatic analyzers via a communication network, and stores analysis information necessary for analyzing a sample A transmission / reception unit that transmits / receives information to / from a management system that aggregates analysis results transmitted from each automatic analyzer, and the transmission / reception unit includes the management system An operation for controlling the reaction between the sample corresponding to the information code read by the information code reading unit and the predetermined reagent using the analysis information received from the system and analyzing the components of the sample based on the result of the reaction And a control unit for performing the above.

  The invention according to claim 2 further includes a storage unit that stores at least one of the information code, the analysis information, the analysis result, and the aggregation result in the invention according to claim 1, wherein the information When the information code read by the code reading unit is not stored in the storage unit, the management system is requested to transmit analysis information of the sample corresponding to the read information code.

  The invention according to claim 3 is the invention according to claim 1 or 2, wherein the transmitting / receiving unit transmits an analysis result of the sample to the management system, while a plurality of analysis results including the analysis result are transmitted to the management system. The tabulation results collected by the server are received from the management system.

  According to a fourth aspect of the present invention, in the invention according to any one of the first to third aspects, the identification information includes a name and a lot number of a sample corresponding to the identification information.

  The invention according to claim 5 is the invention according to any one of claims 1 to 4, characterized in that the sample is one of a quality control sample and a calibration curve creation sample.

  According to a sixth aspect of the present invention, an automatic analyzer that analyzes a component of the sample by reacting the sample with a predetermined reagent is connected to a plurality of automatic analyzers via a communication network, and the analysis of the quality control sample is performed. Of the automatic analyzer for managing the accuracy of the automatic analyzer by storing the analysis information necessary for performing the analysis and communicating with the management system for collecting the analysis results transmitted from each automatic analyzer A quality management method, wherein the automatic analyzer has an information code recording unit that records an information code obtained by coding identification information for identifying a sample, and stores a quality control sample corresponding to the identification information And a vial holding unit that holds the sample vial at a constant temperature, and the information code recording unit of the sample vial held by the vial holding unit records An information code reading step for reading an information code, and when the information code read in the information code reading step is not stored in the storage unit of the automatic analyzer, the management system corresponds to the read information code A request step for requesting transmission of analysis information of the quality control sample to be performed, the quality control sample is reacted with a predetermined reagent using the analysis information received from the management system, and a result of this reaction is optically measured, An analysis step for performing an operation for analyzing a component of the quality control sample based on the measurement result, an analysis result transmission step for transmitting a result of the analysis operation performed in the analysis step to the management system, and the analysis result transmission step A summary result receiving unit for receiving a summary result obtained by the management system summarizing a plurality of analysis results including the analysis result sent in Tsu and up, characterized by at least run the.

  According to a seventh aspect of the invention, an accuracy management program causes the automatic analysis device to execute the accuracy management method of the automatic analysis device according to the sixth aspect.

  According to the present invention, the automatic analyzer accommodates a predetermined sample and has a sample vial having an information code recording unit that records an information code in which identification information for identifying the sample is encoded, and the sample vial is kept at a constant temperature. Connected to a plurality of automatic analyzers via a communication network, a vial holding unit held in a state, an information code reading unit that reads an information code recorded by an information code recording unit of a sample vial held by the vial holding unit, The analysis information necessary for analyzing the sample is stored, and the transmission / reception unit for transmitting / receiving information to / from the management system for collecting the analysis results transmitted from the respective automatic analyzers is received from the management system. The analysis information is used to control the reaction between the sample corresponding to the information code and a predetermined reagent, and based on the result of the reaction, the sample By a control unit for performing an operation for analyzing components, it requires less burden on the operator, while keeping costs it is possible to perform accurate and precise quality control.

  Embodiments of the present invention will be described below with reference to the accompanying drawings. FIG. 1 is an explanatory diagram showing the overall configuration of a network including an automatic analyzer according to an embodiment of the present invention. An automatic analyzer 1 shown in the figure analyzes a component of a sample such as a specimen biochemically or immunologically, and is connected to a management system 3 via a communication network N. A plurality of automatic analyzers 1 are connected to the management system 3 via a communication network N.

  The automatic analyzer 1 dispenses a sample and a reagent into a reaction vessel, optically measures a reaction occurring in the reaction vessel, performs drive control of the measurement mechanism 101, and performs measurement in the measurement mechanism 101. And a control analysis mechanism 102 for analyzing the results, and these two mechanisms cooperate to analyze the components of the sample.

  FIG. 2 is a plan view showing a configuration example of a main part of the measurement mechanism 101 of the automatic analyzer 1. The measurement mechanism 101 shown in FIG. 1 includes a sample transfer unit 11 having a function of storing and transferring a plurality of racks 112 on which sample containers 111 for storing samples such as blood and body fluid are mounted, and a sample vial 121 for storing samples. A sample table 12 that is a vial holding unit to be held, an information code reading unit 13 that reads an information code attached to a sample vial 121 held by the sample table 12, a reaction table 14 that holds a reaction container 141 for reacting a sample and a reagent, And a reagent table 15 for holding the reagent container 151.

  The measurement mechanism 101 also includes a stirring unit 16 that stirs the liquid contained in the reaction vessel 141, a photometric unit 17 that measures the intensity of light passing through the reaction vessel 141, and a cleaning of the reaction vessel 141. A cleaning unit 18 is provided. Furthermore, the measurement mechanism 101 includes a sample dispensing unit 19 that dispenses a sample and a reagent dispensing unit 20 that dispenses a reagent.

  The sample table 12 is rotatable about a vertical line passing through the center of the sample table 12 as a rotation axis by driving a stepping motor under the control of the control unit 25 of the control analysis mechanism 102. The sample vial 121 is transferred to the sample suction position by the sample dispensing unit 19. Since the sample table 12 has such a shape that the sample vial 121 having a predetermined shape can be held as it is, there is no need to perform an operation of transferring the sample in the sample vial 121 to another sample container.

  An openable / closable cover is provided above the sample table 12, while a thermostatic bath is provided below the sample table 12. As a result, the sample vial 121 can be kept at a constant temperature when the cover is closed, and evaporation and denaturation of the sample in the sample vial 121 can be suppressed.

  FIG. 3 is a diagram schematically showing the appearance of the sample vial 121. An information code recording unit 122 for recording an information code for identifying an internal sample is provided on the side surface of the sample vial 121 shown in FIG. The information code recorded by the information code recording unit 122 is obtained by coding the name and lot number of the sample and has a small amount of information. Therefore, a one-dimensional barcode is applied as the information code. In this case, the information code reading unit 13 is realized using a one-dimensional bar code reader.

  On the sample table 12, a sample vial 121 for storing a quality control sample (control) is installed. The sample table 12 can also store emergency specimens and the like. In this case, the specimen is accommodated in a specimen container (vial) having the same shape as the sample vial 121. Note that the sample table 12 may also hold the sample container 111.

  The reaction table 14 transfers the reaction container 141 to a predetermined position in order to dispense a sample or reagent into the reaction container 141, to stir, wash, or measure the light of the reaction container 141. The reaction table 14 is rotatable about a vertical line passing through the center of the reaction table 14 as a rotation axis when the stepping motor is driven under the control of the control unit 25. In addition, similarly to the sample table 12, an openable / closable cover and a thermostatic layer are provided above and below the reaction table 14, respectively (not shown).

  The reagent table 15 has a function of transferring a desired reagent container 151 to a reagent aspirating position by the reagent dispensing unit 20, and, like the above two tables, the stepping motor is driven under the control of the control unit 25. A vertical line passing through the center of the reagent table 15 is rotatable about a rotation axis.

  The stirring unit 16 stirs the sample and the reagent dispensed in the reaction container 141 to promote the reaction. In the case shown in FIG. 2, a stirring bar 162 directed in the vertical direction is attached to the tip of an arm 161 that is movable up and down in the vertical direction. At the time of stirring, the stirring bar 162 enters the reaction vessel 141 and stirs the mixed solution of the sample and the reagent.

  The photometry unit 17 includes a light source 171 that generates light of a predetermined wavelength, and a light receiving unit 172 that receives light emitted from the light source 171 and passed through the reaction vessel 141. Among these, the light receiving unit 172 is realized using a light receiving element that converts the intensity of received light into an electric signal.

  The cleaning unit 18 discharges the mixed solution in the reaction vessel 141 that has been measured by the photometry unit 17 and performs cleaning. Although the washed reaction container 141 is reused, the reaction container 141 may be discarded after completion of one measurement depending on the contents of inspection.

  The sample dispensing unit 19 has a narrow tubular probe 191 that sucks and discharges the sample, and a vertical line that passes through the base end of the probe 191 in order to move the probe 191 in the vertical direction. An arm 192 that freely rotates and an intake / exhaust mechanism using an intake / exhaust syringe or a piezoelectric element are provided (not shown). The sample dispensing unit 19 sucks the sample from the sample container 111 or the sample vial 121 at the sample suction position of the sample transfer unit 11 or the sample table 12, and the sucked sample is placed on the sample dispensing position on the reaction table 14. It discharges to the reaction container 141 in.

  The reagent dispensing unit 20 aspirates the reagent from the reagent container 151 at the reagent aspirating position on the reagent table 15 and discharges the aspirated reagent to the reaction container 141 at the reagent dispensing position on the reaction table 14. To do. The reagent dispensing unit 20 has the same configuration as the sample dispensing unit 19 and includes a thin tubular probe 201, an arm 202, and an intake / exhaust mechanism (not shown).

  The lower ends of the probes 191 and 201 are provided with a liquid level detection function for detecting the liquid level so that only a predetermined length of each probe tip enters from the liquid level even if the liquid level changes. Is set to Thereby, the dispensing accuracy of the sample or reagent in each probe can be maintained, and at the same time, contamination of the probe itself can be prevented.

  The stirring bar 162 and the probes 191 and 201 are cleaned by a cleaning unit (not shown) provided individually after one operation. Instead of performing this cleaning, the used stirring rod 162 and probes 191 and 201 may be discarded and replaced with a new one for each operation. Moreover, you may further provide the dilution dispensing part which hold | maintains and dispenses the dilution liquid which dilutes them to a suitable density | concentration after dispensing a sample and a reagent.

  Next, the configuration of the control analysis mechanism 102 will be described with reference to FIG. The control analysis mechanism 102 is realized by using one or a plurality of computers. The input unit 21 is realized by a pointing device such as a keyboard or a mouse for inputting various information necessary for analysis, and a CRT for outputting and displaying the analysis result and the like. An output unit 22 realized by a display such as a liquid crystal or an organic EL or a printer, and a transmission / reception unit 23 having a function as an interface for transmitting / receiving information according to a predetermined format via a communication network N

  In addition, the control analysis mechanism 102 displays the information code read by the information code reading unit 13, the analysis information related to the analysis of the sample received from the management system 3, the analysis result in the measurement mechanism 101, the total result that the management system 3 tabulates, and the like. And a control unit 25 that controls each function or means in the control analysis mechanism 102 and controls the driving of the measurement mechanism 101.

  The storage unit 24 uses a hard disk that magnetically stores various information, and a memory that loads various programs related to the processing from the hard disk and electrically records them when the automatic analyzer 1 executes the processing. Realized. The storage unit 24 may further include an auxiliary storage device that can read information recorded on a recording medium such as a flexible disk, a CD-ROM, a DVD-ROM, an MO disk, a PC card, and an xD picture card. .

 The control unit 25 includes an analysis calculation unit 251 that performs analysis calculation of the components of the sample based on the measurement result in the measurement mechanism 101, and is realized by a CPU (Central Processing Unit) having control and calculation functions. The control unit 25 reads out the program stored in the storage unit 24 from the memory, thereby executing control and calculation of various operations of the automatic analyzer 1 including the analysis calculation.

  The management system 3 connected to the automatic analyzer 1 having the above configuration via the communication network N will be described. This management system 3 is constructed using one or a plurality of computers, and includes a server 31 for controlling and calculating the management system 3 as a whole, an analysis information database (DB) 32 for storing sample analysis information, and each automatic It has the total information database (DB) 33 which memorize | stores the total information including the analysis result sent from the analyzer 1, and the result which the server 31 totaled the analysis result.

  The communication network N can transmit and receive electrical signals according to a predetermined format, such as the Internet, a telephone network, a packet network, a WAN (Wide Area Network), a wired or wireless LAN (Local Area Network), a dedicated line, and an intranet. It can be anything as long as possible.

  Next, an accuracy management method performed by the automatic analyzer 1 will be described. FIG. 4 is a sequence diagram illustrating an outline of the accuracy management method of the automatic analyzer 1. More specifically, it is a sequence diagram showing an outline of the operation of the automatic analyzer 1 after placing the sample vial 121 on the sample table 12 including communication with the management system 3. In the following description, it is assumed that the automatic analyzer 1 and the management system 3 are in a state in which communication is possible at all times. However, when the transmission source starts transmission of information, communication with the transmission destination is established. May be.

  When the sample vial 121 is installed on the sample table 12, the information code reading unit 13 reads the information code recorded in the information code recording unit 122 of the newly installed sample vial 121 (step S1). Prior to step S 1, the sample table 12 is transferred to the information code reading position A where the information code recording unit 122 of the sample vial 121 to be read faces the information code reading unit 13. In the case shown in FIG. 2, when installing the sample vial 121, the information code recording unit 122 must be installed so as to face the outer periphery of the sample table 12.

  The information code read by the information code reading unit 13 is transmitted to the control unit 25. In the control unit 25, the received information code is searched in the storage unit 24. If the read information code is not stored (No in step S2), the information code is stored in the storage unit 24 and stored. The information code is transmitted from the transmission / reception unit 23 to the management system 3 (step S3).

  When the management system 3 receives the information code from the automatic analyzer 1, the server 31 searches the analysis information database 32 for the analysis information necessary for the analysis using the sample corresponding to the information code, and the read analysis information Is transmitted to the automatic analyzer 1 (steps S4 and S5). This analysis information includes analysis parameters such as analysis items, sample concentrations and expiration dates, sample and reagent dispensing amounts, reference values and allowable values for each analysis item.

  The automatic analyzer 1 that has received the analysis information from the management system 3 displays and outputs the analysis information by the output unit 22 and stores the analysis information in the storage unit 24 (step). S6).

  In the above description, when the information code reading unit 13 reads an information code not stored in the storage unit 24, the automatic analyzer 1 automatically transmits the information code to the management system 3. The operator may select whether or not to transmit the information code each time.

  If the storage unit 24 has already stored the information code read in step S1 (Yes in step S2), the processing in steps S7 and later will be performed without performing the processing in steps S3 to S6 thereafter. move on. However, even if the information code is already stored, it is necessary to obtain the analysis information again when there is a possibility that the analysis information corresponding to the information code has been updated. In such a case, the analysis information stored in the storage unit 24 may be updated by performing the same processing as in steps S3 to S6 described above.

  As described so far, the identification information of the sample contained in the sample vial 121 is read as an information code, and the analysis information corresponding to the identification information included in the read information code is acquired from the management system 3, whereby the management system It becomes possible to acquire the latest analysis information managed by 3.

  Thereafter, the measurement mechanism 101 is in a standby state until the measurement of the sample is started (No in step S7). Information about when to start the measurement of the sample is input from the input unit 21 after the operator installs the sample vial 121. The information input by the operator may be a measurement start time, or a sample measurement cycle (for example, the number of samples to be measured in one cycle). Note that the standby state here means a state in which the measurement mechanism 101 waits for the measurement of the sample, and it is possible to measure a normal specimen during that time.

  When the control unit 25 transmits a control signal for starting measurement of the sample to the measurement mechanism 101, the measurement mechanism 101 starts measurement of the sample (Yes in step S7 and step S8). The measurement of the sample in step S8 may be performed during the measurement of the sample, or may be performed while temporarily interrupting the measurement of the sample.

  Hereinafter, the measurement of the sample in step S8 will be specifically described. First, the reagent dispensing unit 20 dispenses a reagent into the reaction container 141 at a predetermined reagent dispensing position E on the reaction table 14. At this time, under the control of the control unit 25, the reagent table 15 transfers the reagent container 151 containing the reagent to be dispensed to the reaction container 141 to the reagent suction position D. Thereafter, the reagent dispensing unit 20 drives the arm 202 to transfer the probe 201 to the reagent suction position D, and sucks a predetermined amount of the reagent in the reagent container 151. Thereafter, the arm 202 is driven again, and the aspirated reagent is discharged into the reaction container 141 at the reagent dispensing position E of the reaction table 14. Subsequently, the reaction table 14 transfers the reaction container 141 into which the reagent has been dispensed to a predetermined sample dispensing position C.

  Next, the sample dispensing unit 19 dispenses the sample. At this time, under the control of the control unit 25, the arm 192 is driven to suck the sample in the sample vial 121 at the sample suction position B from the probe 191 by a predetermined amount. Thereafter, the arm 192 is driven again, and the sucked sample is discharged into the reaction container 141 at the sample dispensing position C of the reaction table 14.

  Subsequently, the reaction table 14 transfers the reaction container 141 into which the sample and the reagent are dispensed to the stirring position F by the stirring unit 16. The stirrer 16 drives the arm 161 to insert the stirrer 162 into the reaction vessel 141 and stir the mixed solution of the sample and the reagent for a predetermined time.

  Thereafter, the reaction table 14 transfers the reaction vessel 141 that has been agitated to the photometric position G by the photometric unit 17. The light emitted from the light source 171 of the photometry unit 17 passes through the reaction solution (reaction mixture) in the reaction vessel 141 and is received by the light receiving unit 172. The light receiving unit 172 sends a measurement result (electric signal) such as the intensity of the measured light to the control analysis mechanism 102. Thereby, the measurement of the sample in the measurement mechanism 101 (step S8) is completed.

  The measurement method described so far is merely an example, and it goes without saying that the measurement method is appropriately changed according to the type of sample, the analysis item, the type of the automatic analyzer 1, and the like. For example, another reagent may be dispensed after the sample is dispensed.

  After the above-described step S8, the control analysis mechanism 102 that has received the measurement result from the photometry unit 17 reads the analysis information of the sample to be measured from the storage unit 24 by the analysis calculation unit 251 of the control unit 25, and analyzes the measurement result. Calculation is performed (step S9). In this analysis calculation, the absorbance of the reaction solution is calculated based on the measurement result sent from the photometry unit 17, and in addition to this calculation result, a calibration curve obtained from the standard sample and an analysis parameter included in the analysis information are used. To quantitatively determine the components and concentration of the reaction solution.

  The result (analysis result) of the analysis operation analyzed in step S9 is displayed on the output unit 22 or printed and output, and is transmitted to the management system 3 via the transmission / reception unit 23 (step S10).

  The management system 3 that has received the analysis result stores and stores it in the tabulation information database 33 in order to tabulate the received analysis result as new information (step S11).

  The server 31 performs a counting process at the time when analysis results of sample measurement performed under the same conditions gather to some extent. For this reason, in step S12, it waits without performing a totaling calculation until it reaches the period of the totaling process preset with respect to the server 31 (No in step S12). Here, the same condition means that the type of the automatic analyzer 1, the lot number of the sample and the reagent, the analysis parameter, and the like are the same. The period of the aggregation process may be defined by time, or may be defined by the total of analysis results received from each automatic analyzer 1.

  After that, when a predetermined period is reached and aggregation is started (Yes in step S12), the server 31 reads the analysis results to be aggregated from the aggregation information database 33 and executes statistical calculation (step S13). . In this calculation, the average value and standard deviation of the analysis results are calculated, and the deviation value of each analysis result is calculated.

  Thereafter, the server 31 stores and stores the result of the statistical calculation obtained in step S13 in the total information database 33 as the total result, and transmits the analysis result that is an element of the statistical data population in the total. The aggregation results are transmitted to the plurality of automatic analyzers 1 (step S15).

  On the other hand, if the counting process is not started (No in step S12), the analysis received by returning to step S11 when a new analysis result is received from another automatic analyzer 1 (Yes in step S14). Store the results. In other cases (No in step S14), the process returns to step S12 and waits until the counting starts.

  The automatic analyzer 1 that has received the counting results from the management system 3 outputs the received counting results by displaying or printing them on the output unit 22, while storing and storing the counting results in the storage unit 24 ( Step S16). In addition, when receiving a total result from the management system 3, you may set the period received on the automatic analyzer 1 side.

  As described above, after measuring the sample, the measurement result is analyzed, the analysis result is transmitted to the management system 3, and the management system 3 performs statistical analysis together with the analysis results of the other automatic analyzers 1. By receiving the totalized results, it is possible to perform external quality control. That is, according to this embodiment, since the aggregated results can be obtained much more frequently than in the case of normal external precision management (several times a year), there is a discrepancy between the measurement results and the population. However, it becomes possible to grasp the fact at a very early stage.

  According to the embodiment of the present invention described above, by providing the data table on which the sample vial can be installed as it is, the operation of transferring the sample from the vial to the sample container every time measurement is performed or the sample container is installed at a predetermined position. This eliminates the need to perform work, reduces the burden on the worker, further prevents work mistakes, and eliminates waste when transferring the sample vial to the sample container. Cost can be reduced.

  Also, according to this embodiment, analysis information can be obtained by reading the information code attached to the sample vial, so that even if the sample lot is changed, the operator can perform complicated parameter setting. Since there is no need to perform manual input, the burden on the operator can be reduced, and the work time can be shortened and the sample information can be accurately input.

  Furthermore, according to this embodiment, since the total results of analysis contents in each automatic analyzer can be obtained in a shorter period compared with the conventional external system management, there is a discrepancy between the measurement results and the population. Even if it occurs, the fact can always be recognized at an early stage.

  As mentioned above, although one form considered to be the best in practicing the present invention has been described in detail, the present invention is not limited only to this one embodiment. For example, the present invention can be applied not only to a quality control sample but also to a calibration curve creation sample (calibrator) used for creating a calibration curve.

  Thus, the present invention can include various embodiments and the like not described herein, and various design changes and the like can be made without departing from the technical idea specified by the claims. It is possible to apply.

It is explanatory drawing which shows the whole structure of the system containing the automatic analyzer which concerns on one embodiment of this invention. It is explanatory drawing which shows the structure of the automatic analyzer principal part which concerns on one embodiment of this invention. It is a top view which shows the structure of a sample vial. It is a sequence diagram which shows the outline | summary of a process of the quality control method of the automatic analyzer which concerns on one embodiment of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Automatic analyzer 3 Management system 11 Specimen transfer part 12 Sample table 13 Information code reading part 14 Reaction table 15 Reagent table 16 Stirring part 17 Photometric part 18 Washing part 19 Sample dispensing part 20 Reagent dispensing part 21 Input part 22 Output part DESCRIPTION OF SYMBOLS 23 Transmission / reception part 24 Storage part 25 Control part 31 Server 32 Analysis information database 33 Aggregation information database 101 Measurement mechanism 102 Control analysis mechanism 111 Sample container 112 Rack 121 Sample vial 122 Information code recording part 141 Reaction container 151 Reagent container 161,192,202 Arm 162 Stir bar 171 Light source 172 Light receiving unit 191, 201 Probe 251 Analysis operation unit N Communication network

Claims (7)

An automatic analyzer for analyzing the components of the sample by reacting the sample with a predetermined reagent,
A sample vial having an information code recording unit for storing a predetermined sample and recording an information code in which identification information for identifying the sample is encoded;
A vial holding unit for holding the sample vial at a constant temperature;
An information code reading unit for reading an information code recorded by an information code recording unit of a sample vial held by the vial holding unit;
Connected to multiple automatic analyzers via a communication network, stores analysis information necessary for sample analysis, and information with a management system that aggregates the analysis results sent from each automatic analyzer A transmission / reception unit for transmitting / receiving
Using the analysis information received by the transmission / reception unit from the management system, the reaction between the sample corresponding to the information code read by the information code reading unit and a predetermined reagent is controlled, and the sample based on the result of this reaction A control unit for performing an operation for analyzing the components of
An automatic analyzer characterized by comprising: A storage unit that stores at least one of the information code, the analysis information, the analysis result, and the aggregation result;
When the information code read by the information code reading unit is not stored in the storage unit, the management system is requested to transmit analysis information of a sample corresponding to the read information code. The automatic analyzer according to claim 1.   The transmission / reception unit transmits an analysis result of the sample to the management system, and receives a totaling result obtained by the management system totaling a plurality of analysis results including the analysis result from the management system. Item 3. The automatic analyzer according to item 1 or 2.   The automatic analyzer according to claim 1, wherein the identification information includes a name and a lot number of a sample corresponding to the identification information.   The automatic analyzer according to any one of claims 1 to 4, wherein the sample is one of a quality control sample and a calibration curve creation sample. Analysis information necessary for analyzing the quality control sample by connecting an automatic analyzer for analyzing the components of the sample by reacting the sample with a predetermined reagent to a plurality of automatic analyzers via a communication network And an accuracy management method for an automatic analyzer that manages the accuracy of the automatic analyzer by communicating with a management system that aggregates the analysis results transmitted from each automatic analyzer,
The automatic analyzer is
An information code recording unit that records an information code in which identification information for identifying a sample is encoded, and a sample vial for storing a quality control sample corresponding to the identification information, and a vial holding for holding the sample vial in a constant temperature state With
An information code reading step for reading an information code recorded by an information code recording unit of a sample vial held by the vial holding unit;
When the storage unit of the automatic analyzer does not store the information code read in the information code reading step, the analysis information of the quality control sample corresponding to the read information code is transmitted to the management system. Request steps to request; and
An operation for causing the quality control sample to react with a predetermined reagent using the analysis information received from the management system, optically measuring the result of the reaction, and analyzing the components of the quality control sample based on the measurement result Analysis steps to perform,
An analysis result transmission step of transmitting the result of the analysis operation performed in the analysis step to the management system;
A totaling result receiving step of receiving a totaling result obtained by the management system totaling a plurality of analysis results including the analysis result transmitted in the analysis result transmitting step;
An accuracy management method for an automatic analyzer characterized by executing at least   An accuracy management program for causing an automatic analyzer to execute the accuracy management method for an automatic analyzer according to claim 6.

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