JP4414654B2 - サンプル分子を単離および標識するための方法 - Google Patents

サンプル分子を単離および標識するための方法 Download PDF

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JP4414654B2
JP4414654B2 JP2002589762A JP2002589762A JP4414654B2 JP 4414654 B2 JP4414654 B2 JP 4414654B2 JP 2002589762 A JP2002589762 A JP 2002589762A JP 2002589762 A JP2002589762 A JP 2002589762A JP 4414654 B2 JP4414654 B2 JP 4414654B2
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composition
polypeptide
sample
molecule
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JP2005503540A (ja
JP2005503540A5 (enExample
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ルドルフ エイチ． アーバーソルド，
フイリン ゾウ，
ビート リスト，
ジョージ ジェイ． ヴェラ，
サブハシス パーカヤスサ，
サシ ピライ，
Original Assignee
ザ インスティチュート フォー システムズ バイオロジー
ユニヴァーシティ オブ ワシントン
アプライド バイオシステムズ， エルエルシー
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
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  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Peptides Or Proteins (AREA)
JP2002589762A 2001-05-14 2002-05-14 サンプル分子を単離および標識するための方法 Expired - Lifetime JP4414654B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/858,198 US7183116B2 (en) 2001-05-14 2001-05-14 Methods for isolation and labeling of sample molecules
PCT/US2002/015500 WO2002093131A2 (en) 2001-05-14 2002-05-14 Methods for isolating and labeling sample molecules

Related Child Applications (1)

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JP2009113092A Division JP2009175157A (ja) 2001-05-14 2009-05-07 サンプル分子を単離および標識するための方法

Publications (3)

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JP2005503540A JP2005503540A (ja) 2005-02-03
JP2005503540A5 JP2005503540A5 (enExample) 2008-11-06
JP4414654B2 true JP4414654B2 (ja) 2010-02-10

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JP2002589762A Expired - Lifetime JP4414654B2 (ja) 2001-05-14 2002-05-14 サンプル分子を単離および標識するための方法
JP2009113092A Withdrawn JP2009175157A (ja) 2001-05-14 2009-05-07 サンプル分子を単離および標識するための方法

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US (3) US7183116B2 (enExample)
EP (1) EP1456632B1 (enExample)
JP (2) JP4414654B2 (enExample)
CN (1) CN1602422B (enExample)
AT (1) ATE495436T1 (enExample)
AU (1) AU2002303760B2 (enExample)
CA (1) CA2447874C (enExample)
DE (1) DE60238940D1 (enExample)
WO (1) WO2002093131A2 (enExample)

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WO2017010381A1 (ja) * 2015-07-10 2017-01-19 ウシオ電機株式会社 Ｎ末端標識剤、これを用いた蛍光標識タンパク質及びその製造方法

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CA2652991A1 (en) 2001-07-16 2003-11-13 Caprotec Bioanalytics Gmbh Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
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DE60231845D1 (de) * 2001-12-11 2009-05-14 Univ New Jersey Med Diagnoseverfahren für proteinprofilierung
US8110351B2 (en) 2002-01-16 2012-02-07 Invitrogen Dynal As Method for isolating nucleic acids and protein from a single sample
WO2003078962A2 (en) * 2002-03-11 2003-09-25 President And Fellows Of Harvard College Detection and quantification of modified proteins
WO2003077851A2 (en) * 2002-03-11 2003-09-25 Hk Pharmaceuticals, Inc. Compounds and methods for analyzing the proteome
AU2003249692B2 (en) * 2002-06-03 2008-07-31 The Institute For Systems Biology Methods for quantitative proteome analysis of glycoproteins
US20070269895A1 (en) * 2002-06-03 2007-11-22 The Institute For Systems Biology Methods for quantitative proteome analysis of glycoproteins
JP2004170195A (ja) * 2002-11-19 2004-06-17 Reverse Proteomics Research Institute Co Ltd タンパク質の固定化方法
GB0229287D0 (en) * 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
WO2004064972A2 (en) * 2003-01-16 2004-08-05 Hk Pharmaceuticals, Inc. Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
US7794947B2 (en) * 2003-07-10 2010-09-14 Institute For Systems Biology Affinity capture of peptides by microarray and related methods
US20050113584A1 (en) * 2003-07-14 2005-05-26 Irm Llc Methods for the preparation of rhodamine
US20050153306A1 (en) * 2003-07-14 2005-07-14 Irm Llc Fluorogenic enzyme substrates and uses thereof
WO2005015239A2 (en) * 2003-08-07 2005-02-17 Cornell Research Foundation, Inc. Method for n-terminal labeling of proteins
JP4363935B2 (ja) * 2003-09-17 2009-11-11 株式会社豊田中央研究所 生体物質の光固定化・回収方法及び表面プラズモン共鳴センサー
WO2005030981A2 (en) * 2003-09-25 2005-04-07 Invitrogen Corporation Homogeneous populations of molecules
CA2572754A1 (en) * 2004-07-12 2006-02-16 Applera Corporation Mass tags for quantitative analyses
US20070048752A1 (en) * 2004-07-12 2007-03-01 Applera Corporation Mass tags for quantitative analyses
WO2006011673A1 (ja) * 2004-07-30 2006-02-02 Reverse Proteomics Research Institute Co., Ltd. 光切断型リンカーを利用したリガンド固定化固相担体
JP4635532B2 (ja) * 2004-09-14 2011-02-23 株式会社ニコン 生体分子の分析および回収方法
US20060134694A1 (en) * 2004-12-22 2006-06-22 Intel Corporation Methods of protein profiling by thiolation
CA2599731A1 (en) * 2005-03-03 2006-09-08 Dmi Biosciences, Inc. Quantification of proteins
EP2322920B1 (en) * 2005-06-07 2014-12-10 Centre National de la Recherche Scientifique (CNRS) MALDI tissue imaging using conjugates cleavable by fast fragmentation
GB0515323D0 (en) * 2005-07-26 2005-08-31 Electrophoretics Ltd Mass labels
US7906341B2 (en) * 2006-06-30 2011-03-15 Dh Technologies Development Pte, Ltd. Methods, mixtures, kits and compositions pertaining to analyte determination
JP2009544974A (ja) 2006-07-21 2009-12-17 ライフ テクノロジーズ コーポレーション 鮮明に分解する標識タンパク質分子量標準
CA2671859C (en) * 2006-12-07 2016-07-12 Applied Isotope Technologies, Inc. Solid phase and catalyzed enabled automated isotope dilution and speciated isotope dilution mass spectrometry
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US20180217156A1 (en) * 2015-07-29 2018-08-02 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Means and methods for a sample preparation, especially for mass spectrometry
CN110687297B (zh) * 2018-07-06 2023-08-22 复旦大学 基于稳定同位素半胱氨酸代谢标记的棕榈酰化修饰蛋白质定量分析方法
GB201913598D0 (en) * 2019-09-20 2019-11-06 Univ Birmingham Labelling of biomolecules
CN113075114B (zh) * 2019-12-17 2022-07-01 北京大学 一种用于单细胞分析的有机质谱流式分析方法
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Also Published As

Publication number Publication date
DE60238940D1 (de) 2011-02-24
CA2447874A1 (en) 2002-11-21
CA2447874C (en) 2010-08-31
JP2009175157A (ja) 2009-08-06
ATE495436T1 (de) 2011-01-15
CN1602422A (zh) 2005-03-30
EP1456632A2 (en) 2004-09-15
AU2002303760B2 (en) 2008-04-10
US20040110186A1 (en) 2004-06-10
WO2002093131A3 (en) 2004-05-27
US7364911B2 (en) 2008-04-29
JP2005503540A (ja) 2005-02-03
US20020168644A1 (en) 2002-11-14
WO2002093131A2 (en) 2002-11-21
EP1456632A4 (en) 2005-04-20
EP1456632B1 (en) 2011-01-12
CN1602422B (zh) 2011-06-08
US20040265810A1 (en) 2004-12-30
US7183116B2 (en) 2007-02-27

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