JP4381820B2 - 生体組織検査用マイクロ抽出装置 - Google Patents

生体組織検査用マイクロ抽出装置 Download PDF

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Publication number
JP4381820B2
JP4381820B2 JP2003574050A JP2003574050A JP4381820B2 JP 4381820 B2 JP4381820 B2 JP 4381820B2 JP 2003574050 A JP2003574050 A JP 2003574050A JP 2003574050 A JP2003574050 A JP 2003574050A JP 4381820 B2 JP4381820 B2 JP 4381820B2
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fiber
extraction
sample
coated
animal
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JP2005519669A (ja
JP2005519669A5 (https=
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ポーリスツィン、ジャヌス・ビー
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/405Concentrating samples by adsorption or absorption
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045Devices for taking samples of body liquids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/34Trocars; Puncturing needles
    • A61B17/3403Needle locating or guiding means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N2030/009Extraction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • G01N2030/062Preparation extracting sample from raw material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biochemistry (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2003574050A 2002-03-11 2003-03-06 生体組織検査用マイクロ抽出装置 Expired - Fee Related JP4381820B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US36421402P 2002-03-11 2002-03-11
US39330902P 2002-07-03 2002-07-03
US42100102P 2002-10-25 2002-10-25
US42151002P 2002-10-28 2002-10-28
US42783302P 2002-11-21 2002-11-21
PCT/CA2003/000311 WO2003075772A2 (en) 2002-03-11 2003-03-06 Micro-devices and analytical procedures for investigation of biological systems

Publications (3)

Publication Number Publication Date
JP2005519669A JP2005519669A (ja) 2005-07-07
JP2005519669A5 JP2005519669A5 (https=) 2006-04-20
JP4381820B2 true JP4381820B2 (ja) 2009-12-09

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Country Link
US (2) US7384794B2 (https=)
EP (1) EP1482840B1 (https=)
JP (1) JP4381820B2 (https=)
AT (1) ATE416675T1 (https=)
AU (1) AU2003208226A1 (https=)
DE (1) DE60325180D1 (https=)
WO (1) WO2003075772A2 (https=)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017193213A1 (en) 2016-05-10 2017-11-16 Jp Scientific Limited System and method for desorbing and detecting an analyte sorbed on a solid phase microextraction device
US20090026122A1 (en) 2002-03-11 2009-01-29 Janusz Biocompatible solid-phase microextraction coatings and methods for their preparation
US20170241877A1 (en) * 2002-03-11 2017-08-24 Janusz B. Pawliszyn System and method for desorbing and detecting an analyte sorbed on a solid phase microextraction device
DE60325180D1 (de) * 2002-03-11 2009-01-22 Janusz B Pawliszyn Mikrovorrichtungen zur untersuchung von biologischen systemen
US8598325B2 (en) 2002-03-11 2013-12-03 Janusz B. Pawliszyn Solid-phase microextraction coatings and methods for their preparation
US9733234B2 (en) 2002-03-11 2017-08-15 Jp Scientific Limited Probe for extraction of molecules of interest from a sample
US7232689B2 (en) * 2002-03-11 2007-06-19 Pawliszyn Janusz B Calibration procedure for investigating biological systems
US9870907B2 (en) 2002-03-11 2018-01-16 Jp Scientific Limited Probe for extraction of molecules of interest from a sample
US20040195503A1 (en) * 2003-04-04 2004-10-07 Taeman Kim Ion guide for mass spectrometers
EG23584A (en) * 2003-11-11 2006-09-11 Ali Mokhtar Al-Hossary Amr Elimination of myoglobin from blood using an i v filter
JP4320342B2 (ja) * 2004-08-17 2009-08-26 独立行政法人科学技術振興機構 希土類蛍光錯体を用いた標識方法と分析検出法
GB0510171D0 (en) * 2005-05-18 2005-06-22 Mass Spec Analytical Ltd Mass spectrometer apparatus
US7645286B2 (en) 2005-05-20 2010-01-12 Neotract, Inc. Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures
US8668705B2 (en) 2005-05-20 2014-03-11 Neotract, Inc. Latching anchor device
US9504461B2 (en) 2005-05-20 2016-11-29 Neotract, Inc. Anchor delivery system
US10925587B2 (en) 2005-05-20 2021-02-23 Neotract, Inc. Anchor delivery system
US8603106B2 (en) 2005-05-20 2013-12-10 Neotract, Inc. Integrated handle assembly for anchor delivery system
US10195014B2 (en) 2005-05-20 2019-02-05 Neotract, Inc. Devices, systems and methods for treating benign prostatic hyperplasia and other conditions
US7758594B2 (en) 2005-05-20 2010-07-20 Neotract, Inc. Devices, systems and methods for treating benign prostatic hyperplasia and other conditions
US9549739B2 (en) 2005-05-20 2017-01-24 Neotract, Inc. Devices, systems and methods for treating benign prostatic hyperplasia and other conditions
US8628542B2 (en) 2005-05-20 2014-01-14 Neotract, Inc. Median lobe destruction apparatus and method
ITFI20050194A1 (it) * 2005-09-16 2007-03-17 Esposti Filippo Degli Apparecchiatura di campionamento automatico per microestrazione in fase solida (spme)
US20080023630A1 (en) * 2005-11-22 2008-01-31 Ciphergen Biosystems Inc. Polymer probe doped with conductive material for mass spectrometry
JP2007205867A (ja) * 2006-02-01 2007-08-16 Shinwa Kako Kk アルデヒド・ケトン類分析用繊維充填ニードル、分析装置及び分析方法
US20070259445A1 (en) * 2006-05-05 2007-11-08 Blas Cerda Quantitative analysis of surface-derived samples using mass spectrometry
US10434492B2 (en) * 2007-01-26 2019-10-08 Sigma-Aldrich Co. Llc Compositions and methods for solid phase extraction of lipids
US10928366B2 (en) * 2007-01-26 2021-02-23 Sigma-Aldrich Co. Llc Compositions and methods for combining protein precipitation and solid phase extraction
US8088097B2 (en) 2007-11-21 2012-01-03 Glumetrics, Inc. Use of an equilibrium intravascular sensor to achieve tight glycemic control
US7728287B2 (en) 2007-03-01 2010-06-01 Lawrence Livermore National Security, Llc Imaging mass spectrometer with mass tags
US20100168609A1 (en) * 2007-03-14 2010-07-01 Ogeno Gmbh Biopsy device for the enrichment of tissue, cells, or analytes
CA2686065A1 (en) 2007-05-10 2008-11-20 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
JP5395076B2 (ja) * 2008-07-22 2014-01-22 アークレイ株式会社 キャピラリー電気泳動法による分析装置および分析方法
US9500572B2 (en) 2009-04-30 2016-11-22 Purdue Research Foundation Sample dispenser including an internal standard and methods of use thereof
US20110077477A1 (en) 2009-09-30 2011-03-31 Glumetrics, Inc. Sensors with thromboresistant coating
DE112010004778A5 (de) * 2009-10-20 2013-03-14 Ogeno Gmbh Biopsie-instrument umfassend ein magnetisches element
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
WO2011137178A1 (en) * 2010-04-27 2011-11-03 Glumetrics, Inc. Deployment system and method for optical analyte sensor
US20120228490A1 (en) * 2011-03-13 2012-09-13 Excellims Corporation Apparatus and method for ion mobility spectrometry and sample introduction
US8895918B2 (en) * 2011-06-03 2014-11-25 Purdue Research Foundation Ion generation using modified wetted porous materials
WO2013036585A1 (en) * 2011-09-06 2013-03-14 The Trustees Of The University Of Pennsylvania Activation and expansion of t cell subsets using biocompatible solid substrates with tunable rigidity
US10292801B2 (en) 2012-03-29 2019-05-21 Neotract, Inc. System for delivering anchors for treating incontinence
CA2870439C (en) * 2012-04-19 2018-02-06 New Objective, Inc. Method and apparatus for combined sample preparation and nanoelectrospray ionization mass spectrometry
US10130353B2 (en) 2012-06-29 2018-11-20 Neotract, Inc. Flexible system for delivering an anchor
KR101393125B1 (ko) 2012-07-20 2014-05-08 김기수 진피추출기
US9733228B2 (en) 2013-01-31 2017-08-15 Purdue Research Foundation Methods of analyzing crude oil
WO2014120411A1 (en) 2013-01-31 2014-08-07 Purdue Research Foundation Systems and methods for analyzing an extracted sample
WO2014209474A1 (en) 2013-06-25 2014-12-31 Purdue Research Foundation Mass spectrometry analysis of microorganisms in samples
JP6061302B2 (ja) * 2013-06-26 2017-01-18 国立大学法人浜松医科大学 試料分析装置
EP3129464B1 (en) 2014-04-10 2019-08-28 The Trustees of Columbia University in the City of New York Methods, compositions, and systems for activation and expansion of cells
US9786478B2 (en) 2014-12-05 2017-10-10 Purdue Research Foundation Zero voltage mass spectrometry probes and systems
CN107960130A (zh) 2015-02-06 2018-04-24 普度研究基金会 探针、系统、盒及其使用方法
WO2016134324A1 (en) * 2015-02-20 2016-08-25 Neoteryx, Llc Method and apparatus for acquiring blood for testing
US10734216B2 (en) 2015-05-11 2020-08-04 The University Of North Carolina At Chapel Hill Pressure driven fluidic injection for chemical separations by electrophoresis
US9606082B2 (en) 2015-05-11 2017-03-28 The University Of North Carolina At Chapel Hill Pressure driven microfluidic injection for chemical separations
US10191061B2 (en) 2015-08-20 2019-01-29 King Fahd University Of Petroleum And Minerals Microwave-assisted headspace liquid-phase microextraction of an analyte
WO2017040359A1 (en) 2015-08-28 2017-03-09 Indiana University Research And Technology Corporation Atmospheric-pressure ionization and fragmentation of molecules for structural elucidation
US9728387B2 (en) 2015-10-20 2017-08-08 The University Of North Carolina At Chapel Hill Solid phase extraction with capillary electrophoresis
JP6930986B2 (ja) 2016-03-02 2021-09-01 ジェイ・ピィ・サイエンティフィック・リミテッドJp Scientific Limited サンプルから成分を抽出するための方法および装置
JP6930978B2 (ja) 2016-03-02 2021-09-01 ジェイ・ピィ・サイエンティフィック・リミテッドJp Scientific Limited 固相マイクロ抽出用コーティング
CN114544312A (zh) * 2016-06-03 2022-05-27 普度研究基金会 用于分析使用吸附材料从样品中提取的分析物的系统和方法
CN106093067B (zh) * 2016-07-27 2018-08-14 温州职业技术学院 一种采血针自动组装机的检测装置
US10345201B2 (en) 2016-08-28 2019-07-09 Alireza Ghiasvand Polypyrrole/graphene oxide nanocomposite-coated fiber located in a capillary tube reinforced by a vacuum system for assessment of oxidative stability of edible oils
US11092522B2 (en) 2017-03-01 2021-08-17 Janusz Pawliszyn Devices to facilitate sampling with thin film solid phase microextraction
CN106959349B (zh) 2017-04-17 2019-04-26 武汉大学 一种微柱富集进样方法
SG11202005766XA (en) 2017-12-23 2020-07-29 Neotract Inc Expandable tissue engagement apparatus and method
EP3578972A1 (en) * 2018-06-06 2019-12-11 Blink AG A device for fractionating a suspension sample
US12105062B2 (en) * 2018-09-05 2024-10-01 Bae Systems Information And Electronic Systems Integration Inc. Carbide-derived carbon for solid-phase micro extraction media
WO2020096827A1 (en) 2018-11-07 2020-05-14 Neotract, Inc. System for delivery of a fiducial marker
CN109223136A (zh) * 2018-11-20 2019-01-18 林平珍 一种新型妇产科用羊水穿刺定位装置
AU2020298543A1 (en) * 2019-07-01 2022-01-06 Perkinelmer U.S. Llc PDMS granular coated vial
JP7348626B2 (ja) * 2019-07-17 2023-09-21 国立大学法人山梨大学 生体試料の状態評価装置、システム、方法、およびプログラム
EP4018178B1 (en) * 2019-08-20 2025-07-30 Restek Corporation Solid phase microextraction system
JP7739288B2 (ja) 2019-11-27 2025-09-16 レステック・コーポレーション 固相マイクロ抽出装置および形成方法
CN111297451A (zh) * 2020-03-23 2020-06-19 钟琼 一种肿瘤科用穿刺定位器
FI3989844T3 (fi) 2020-08-03 2023-11-20 Teleflex Life Sciences Ltd Kahva ja patruunajärjestelmä lääketieteellisiin toimenpiteisiin

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476231A (en) 1981-07-22 1984-10-09 International Remote Imaging Systems, Inc. Method of analyzing the distribution of a reagent between particles and liquid in a suspension
US4616652A (en) * 1983-10-19 1986-10-14 Advanced Cardiovascular Systems, Inc. Dilatation catheter positioning apparatus
US5120510A (en) * 1986-10-10 1992-06-09 Minnesota Mining And Manufacturing Company Sensor and method for sensing the concentration of a component in a medium
US5047437A (en) 1988-11-23 1991-09-10 American Cyanamid Porous polyacrylonitrile beads and process for their production
US5691206A (en) * 1990-04-02 1997-11-25 Pawliszyn; Janusz B. Method and device for solid phase microextraction and desorption
GB9007356D0 (en) * 1990-04-02 1990-05-30 Pawliszyn Janusz B Micro solid phase extraction with fused silica optical fibres
US5424187A (en) * 1991-06-14 1995-06-13 Board Of Regents Of The University Of Washington Method of screening for arterial chlamydial granuloma
FI96379C (fi) * 1992-10-16 1996-06-25 Instrumentarium Oy Menetelmä ja laitteisto näytteen analysoimiseksi
US5460813A (en) 1993-04-05 1995-10-24 National Jewish Center For Immunology And Respiratory Medicine Method for treating Kawasaki syndrome by administration of an anti-TSST-1 agent which is not gamma globulin
US5464395A (en) * 1994-04-05 1995-11-07 Faxon; David P. Catheter for delivering therapeutic and/or diagnostic agents to the tissue surrounding a bodily passageway
US5640470A (en) * 1995-03-27 1997-06-17 Abbott Laboratories Fiber-optic detectors with terpolymeric analyte-permeable matrix coating
US5693228A (en) * 1995-09-28 1997-12-02 Varian Associates, Inc. Method and device for vibration during solid phase microextraction
US6750031B1 (en) * 1996-01-11 2004-06-15 The United States Of America As Represented By The Secretary Of The Navy Displacement assay on a porous membrane
US5830184A (en) * 1996-03-06 1998-11-03 Medical Components, Inc. Composite catheter stabilizing devices, methods of making the same and catheter extracting device
US6103535A (en) 1996-05-31 2000-08-15 University Of Maryland Optical fiber evanescent field excited fluorosensor and method of manufacture
US5798266A (en) * 1996-08-27 1998-08-25 K-Quay Enterprises, Llc Methods and kits for obtaining and assaying mammary fluid samples for breast diseases, including cancer
US6743180B1 (en) * 1997-08-15 2004-06-01 Rijksuniversiteit Leiden Pressure sensor for use in an artery
JP3481828B2 (ja) * 1997-08-26 2003-12-22 株式会社日立製作所 電気泳動分析装置,電気泳動分析方法及びそれに用いる試料容器
US6360588B1 (en) 1998-10-27 2002-03-26 Edward Allan Ross Materials and methods for the analysis of substances passing through a membrane
DE19905239B4 (de) * 1999-02-02 2006-08-24 Wendt, Oliver, Dipl.-Ing. Positioniereinrichtung zur Positionierung von medizinischen Werkzeugen zur MR-gestützten Untersuchung und Behandlung von Körperteilen
US6815216B2 (en) 1999-03-26 2004-11-09 Gerstel Systemtechnik Gmbh & Co. Kg Method for solid-phase microextraction and analysis, and a collector for this method
US6167297A (en) * 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
GB0006046D0 (en) * 2000-03-13 2000-05-03 Univ Warwick Time of flight mass spectrometry apparatus
AU2001246608A1 (en) * 2000-03-17 2001-09-24 Albert-Claude Benhamou Device for in situ analysis and/or treatment with flexible rod
US20020034827A1 (en) 2000-08-01 2002-03-21 Rajendra Singh Methods for solid phase nanoextraction and desorption
US20040005582A1 (en) 2000-08-10 2004-01-08 Nanobiodynamics, Incorporated Biospecific desorption microflow systems and methods for studying biospecific interactions and their modulators
JP2004535563A (ja) 2001-04-26 2004-11-25 ヴァリアン インコーポレーテッド 中空繊維膜のサンプル調製デバイス
US6871556B2 (en) * 2001-07-27 2005-03-29 The Regents Of The University Of California Porous protective solid phase micro-extractor sheath
US20030135195A1 (en) * 2002-01-16 2003-07-17 Oscar Jimenez Highly lubricious hydrophilic coating utilizing dendrimers
WO2003076927A1 (en) * 2002-03-05 2003-09-18 North Carolina State University Method and apparatus for determining a molecular descriptor of absorption for a candidate compound
US7232689B2 (en) * 2002-03-11 2007-06-19 Pawliszyn Janusz B Calibration procedure for investigating biological systems
DE60325180D1 (de) * 2002-03-11 2009-01-22 Janusz B Pawliszyn Mikrovorrichtungen zur untersuchung von biologischen systemen
US7259019B2 (en) * 2002-03-11 2007-08-21 Pawliszyn Janusz B Multiple sampling device and method for investigating biological systems
KR101107765B1 (ko) 2002-08-06 2012-01-25 싸이퍼젠 바이오시스템즈, 인코포레이티드 난소암의 검출을 위한 생물 마커의 용도
US7981362B2 (en) 2003-11-04 2011-07-19 Meso Scale Technologies, Llc Modular assay plates, reader systems and methods for test measurements

Also Published As

Publication number Publication date
JP2005519669A (ja) 2005-07-07
WO2003075772A3 (en) 2004-02-05
ATE416675T1 (de) 2008-12-15
DE60325180D1 (de) 2009-01-22
US8114660B2 (en) 2012-02-14
EP1482840B1 (en) 2008-12-10
US20050118599A1 (en) 2005-06-02
WO2003075772A2 (en) 2003-09-18
US20110104027A1 (en) 2011-05-05
EP1482840A2 (en) 2004-12-08
AU2003208226A1 (en) 2003-09-22
US7384794B2 (en) 2008-06-10

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