JP4328019B2 - トロポニンｉおよびトロポニンｃを含む一本鎖ポリペプチド - Google Patents

トロポニンｉおよびトロポニンｃを含む一本鎖ポリペプチド Download PDF

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Publication number
JP4328019B2
JP4328019B2 JP2000539135A JP2000539135A JP4328019B2 JP 4328019 B2 JP4328019 B2 JP 4328019B2 JP 2000539135 A JP2000539135 A JP 2000539135A JP 2000539135 A JP2000539135 A JP 2000539135A JP 4328019 B2 JP4328019 B2 JP 4328019B2
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Japan
Prior art keywords
troponin
chain
sequence
polypeptide
chain polypeptide
Prior art date
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Expired - Lifetime
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JP2000539135A
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English (en)
Japanese (ja)
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JP2002508181A5 (enExample
JP2002508181A (ja
Inventor
シー，クインウェイ
ソン，キアンーリイ
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Spectral Diagnostics inc
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Spectral Diagnostics inc
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Publication of JP2002508181A5 publication Critical patent/JP2002508181A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2000539135A 1997-12-18 1998-12-18 トロポニンｉおよびトロポニンｃを含む一本鎖ポリペプチド Expired - Lifetime JP4328019B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/993,380 1997-12-18
US08/993,380 US6077676A (en) 1997-12-18 1997-12-18 Single-chain polypeptides comprising troponin I and troponin C
PCT/IB1998/002095 WO1999031235A1 (en) 1997-12-18 1998-12-18 Single-chain polypeptides comprising troponin i and troponin c

Publications (3)

Publication Number Publication Date
JP2002508181A JP2002508181A (ja) 2002-03-19
JP2002508181A5 JP2002508181A5 (enExample) 2006-01-05
JP4328019B2 true JP4328019B2 (ja) 2009-09-09

Family

ID=25539476

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000539135A Expired - Lifetime JP4328019B2 (ja) 1997-12-18 1998-12-18 トロポニンｉおよびトロポニンｃを含む一本鎖ポリペプチド

Country Status (9)

Country Link
US (1) US6077676A (enExample)
EP (1) EP1037976B1 (enExample)
JP (1) JP4328019B2 (enExample)
AT (1) ATE309351T1 (enExample)
AU (1) AU1444699A (enExample)
CA (1) CA2315282C (enExample)
DE (1) DE69832299T2 (enExample)
ES (1) ES2253835T3 (enExample)
WO (1) WO1999031235A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2756827B1 (fr) * 1996-12-05 1999-01-29 Pasteur Sanofi Diagnostics Composes synthetiques biepitopiques utilisables comme etalons dans les dosages biologiques de la troponine i
US6475785B1 (en) * 1997-12-18 2002-11-05 Spectral Diagnostics, Inc. Single-chain polypeptides comprising troponin I N-terminal fragments and troponin C
AU6117099A (en) 1998-10-21 2000-05-08 Spectral Diagnostics Inc. Cardiac troponin i polypeptide fragments and uses in diagnostics
US7078486B2 (en) * 1999-12-10 2006-07-18 Spectral Diagnostics, Inc. Single-chain polypeptides comprising troponin I and troponin C
US20070141710A1 (en) * 2005-12-20 2007-06-21 Beckman Coulter, Inc. Stable calibrators for immunoassays
US20110306148A1 (en) 2010-06-14 2011-12-15 Siemens Healthcare Diagnostics Inc. Composition for use as an assay reagent
CN107245103A (zh) * 2016-12-30 2017-10-13 广西壮族自治区药用植物园 抗肿瘤重组蛋白ifti及其编码基因与应用
CN107245102A (zh) * 2016-12-30 2017-10-13 广西壮族自治区药用植物园 抗肿瘤重组蛋白gpti及其编码基因与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892827A (en) * 1986-09-24 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
CA2027434C (en) * 1990-10-12 1999-01-05 George Jackowski Diagnostic kit for diagnosing and distinguishing chest pain in early onset thereof
US5604105B1 (en) * 1990-10-12 1999-08-24 Spectral Diagnostics Inc Method and device for diagnosingand distinguishing chest pain in early onset thereof
EP0651805B1 (en) * 1992-07-17 2006-12-13 Dana Farber Cancer Institute Method of intracellular binding of target molecules
FR2701954B1 (fr) * 1993-02-23 1995-07-07 Pasteur Sanofi Diagnostics Composition stabilisée de troponine pour immunoessais et procédé de stabilisation de troponine pour immunoessais.
DE805821T1 (de) * 1995-11-29 1998-05-14 Dade Int Inc MENSCHLICHES HERZ-CNBr TROPONIN I-ISOFORM UND DESSEN VERWENDUNG
FI104857B (fi) * 1996-01-15 2000-04-14 Hytest Oy Sydänlihaksen soluvaurioiden asteen mittaus immunokemiallisella menetelmällä sisältäen menetelmään soveliaat vasta-aineet
AU2667197A (en) * 1996-04-16 1997-11-07 University Of Miami Stabilized preparations of human troponins and modifications thereof, diagnostic assay methods and assay kits
WO1998016255A2 (en) * 1996-10-15 1998-04-23 Navix, Inc. Stabilized conjugates of uncomplexed subunits of multimeric proteins
US5834210A (en) * 1997-05-23 1998-11-10 Spectral Diagnostics, Inc. Stable troponin subunits and complexes
WO1998054219A1 (en) * 1997-05-29 1998-12-03 Medical Analysis Systems Inc. Covalently coupled troponin complexes

Also Published As

Publication number Publication date
DE69832299T2 (de) 2006-08-10
CA2315282C (en) 2012-10-23
EP1037976B1 (en) 2005-11-09
DE69832299D1 (de) 2005-12-15
CA2315282A1 (en) 1999-06-24
AU1444699A (en) 1999-07-05
EP1037976A1 (en) 2000-09-27
ES2253835T3 (es) 2006-06-01
US6077676A (en) 2000-06-20
JP2002508181A (ja) 2002-03-19
ATE309351T1 (de) 2005-11-15
WO1999031235A1 (en) 1999-06-24

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